Emilin1 Rat Monoclonal Antibody [Clone ID: C11A8]

SKU
AM31889PU-N
Emilin1 rat monoclonal antibody, clone C11A8, Purified
  $415.00
2 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Clone Name C11A8
Application IF, IHC, WB
Recommended Dilution Western Blot: 2-10 µg/ml.
Immunofluorescence.
Immunohistochemistry on Frozen Sections.
Reactivity Mouse
Antibody Host Rat
Isotype IgG2a
Clonality Monoclonal
Immunogen Recombinant Mouse Emilin-1
Specificity This antibody was selected for its ability to detect Murine Emilin-1.
Buffer PBS
State: Purified
State: Lyophilized (0.2 μm filtered) purified IgG fraction
Reconstitution Method Restore in sterile water to a concentration is 0.1-1.0 mg/ml. Centrifuge vial prior to opening.
Purification Affinity Chromatography on Protein G
Conjugation Unconjugated
Storage Prior to reconstitution store at 2-8°C for one month or at -20°C for longer.
Following reconstitution store undiluted at 2-8°C for one month
or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Shipping Ambient
Gene Name elastin microfibril interfacer 1
Database Link
Background Emilin-1 is an extracellular matrix glycoprotein localized at sites where elastin and microfibrils are in proximity. It may be responsible for anchoring smooth muscle cells to elastic fibers. It has cell adhesive capacity. Emilin-1 may have a role in the regulation of blood vessel assembly since it inhibits TGFB signaling by binding specifically to the pro-TGFB precursor and preventing its maturation by furin convertases in the extracellular space. TGFB proteins are the main regulators of blood vessel development and maintenance.
Synonyms EMILIN-1, EMI
Reference Data
Protein Categories Growth Factors, Intracellular Proteins, Nervous system: Neurodegenerative diseases, Secreated Proteins
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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