CD1B Mouse Monoclonal Antibody [Clone ID: SN13]
Specifications
| Product Data | |
| Clone Name | SN13 |
|---|---|
| Application | IHC, IP |
| Recommended Dilution | Flow cytometry. Immunoprecipitation. Immunohistochemistry on frozen sections. Immunohistochemistry on paraffin sections. |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | A cell membrane antigen preparation that was isolated from normal human thymocytes |
| Specificity | This antibody recognizes CD1b, a 44 kDa type I glycoprotein associated with beta2-microglobulin. It is expressed on dendritic cells, Langerhans cells, thymocytes, and T acute lymphoblastic leukemia cells. |
| Buffer | Phosphate buffered saline (PBS) State: Purified State: Liquid Ig fraction Preservative: 15 mM sodium azide, approx. pH 7.4 |
| Concentration | lot specific |
| Purification | Protein-A affinity chromatography (> 95% pure by SDS-PAGE) |
| Conjugation | Unconjugated |
| Storage | Store undiluted at 2-8°C. DO NOT FREEZE! |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | CD1b molecule |
| Database Link | |
| Background | CD1b (also known as R1) together with CD1a and c, belongs to group 1 of CD1 antigens. These non-classical MHC-like glycoproteins serve as antigen-presenting molecules for a subset of T cells that responds to specific lipids and glycolipids found in the cell walls of bacterial pathogens or self-glycolipid antigens such as gangliosides, and they have also roles in antiviral immunity. The trafficking routes of the particular CD1 types differ and correspond to their ability to bind and present different groups of antigens. Besides non-peptide glycolipid antigen presentation to CD1-restricted T cells, CD1b has been implicated in thymocyte development. |
| Synonyms | CD1; CD1A; MGC125990; MGC125991; R1 |
| Reference Data | |
| Protein Categories | CD Markers, Membrane Proteins |
Reviews
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Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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