LILRB1 Mouse Monoclonal Antibody [Clone ID: GHI/75]
$310.00
2 Weeks*
Specifications
| Product Data | |
| Clone Name | GHI/75 |
|---|---|
| Application | FC, FN, IP, WB |
| Recommended Dilution | Flow cytometry. Immunoprecipitation. Western blot. Functional application: blocking HLA-G induced TGF-beta1 production. |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG2b |
| Clonality | Monoclonal |
| Immunogen | Hairy cell leukaemia cells |
| Specificity | This antibody recognizes CD85j / ILT2, an 110-120 kDa membrane glycoprotein expressed strongly on plasma cells, moderately on circulating B cells, and weakly on monocytes. It is also expressed on T cell and NK cell subsets (variable, individual). |
| Buffer | Phosphate buffered saline (PBS) State: Purified State: Liquid Ig fraction Preservative: 15 mM sodium azide, approx. pH 7.4 |
| Concentration | lot specific |
| Purification | Protein-A affinity chromatography |
| Conjugation | Unconjugated |
| Storage | Store undiluted at 2-8°C. DO NOT FREEZE! |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | leukocyte immunoglobulin like receptor B1 |
| Database Link | |
| Background | CD85j, also known as ILT-2 (Ig-like transcript 2), LIR-1 (leukocyte Ig-like receptor 1), or LILRB1 (leukocyte Ig-like receptor B1), is a member of Ig superfamily transmembrane glycoproteins named CD85. The CD85j protein is expressed on several types of immune cells (plasma cells, B cells, monocytes, T and NK cell subsets) where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. |
| Synonyms | LILR-B1, ILT2, LIR1, MIR7, LIR-1, ILT-2, MIR-7 |
| Reference Data | |
| Protein Categories | Membrane Proteins |
Reviews
Documents
| Product Manuals |
| FAQs |
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Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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