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liver FABP (FABP1) Mouse Monoclonal Antibody [Clone ID: L2B10]

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SKU
AM26273PU-N
liver FABP (FABP1) mouse monoclonal antibody, clone L2B10, Purified
Size:
100 ug
Conjugation:
Unconjugated
  $665.00
2 Weeks*
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View other "FABP1" antibodies

Specifications
Specifications
Product Data
Clone Name L2B10
Application ELISA, IHC, WB
Recommended Dilution Immunoassay.
Western blot.
Immunohistochemistry on Fozen Sections.
Immunohistochemistry on Paraffin Sections.
Recommended Dilutions: Use 1/50 as a starting working dilution for immunohistochemistry and Western blotting.
Reactivity Baboon, Canine, Human, Porcine, Rat
Antibody Host Mouse
Isotype IgG2b
Clonality Monoclonal
Specificity The monoclonal antibody L2B10 recognizes Human Liver Fatty Acid Binding Protein (L-FABP) of both natural and recombinant origin.
The monoclonal antibody L2B10 is useful to detect ischemic areas of Human liver. Furthermore, the antibody can be used for the purification of Human L-FABP.
Weak reactivity with Human H-FABP.
Buffer PBS
State: Purified
State: Liquid 0.2 µm filtered Ig fraction
Stabilizer: 0.1% BSA
Preservative: 0.02% Sodium Azide
Concentration lot specific
Purification Protein G Chromatography
Conjugation Unconjugated
Storage Store undiluted at 2-8°C.
DO NOT FREEZE!
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Gene Name fatty acid binding protein 1
Database Link
Background The L-FABP protein is derived from the human FABP1 gene. FABPs are small intracellular proteins (~13-14 kDa) with a high degree of tissue specificity that bind long chain fatty acids. They are abundantly present in various cell types and play an important role in the intracellular utilization of fatty acids, transport and metabolism. There are at least nine distinct types of FABP, each showing a specific pattern of tissue expression. Due to its small size, FABP leaks rapidly out of ischemically damaged necrotic cells leading to a rise in serum levels. Ischemically damaged tissues are characterized histologically by absence (or low presence) of FABP facilitating recognition of such areas. L-FABP is localized in the liver, kidney and intestinal epithelium.
Synonyms FABPL, L-FABP, Liver-type fatty acid-binding protein
Reference Data
Protein Categories Intracellular Proteins
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Documents
Resources

file-alt Citations

Re-Recognizing the Cellular Origin of the Primary Epithelial Tumors of the Liver
Feng, Zhu, Yin et al
J Hepatocell Carcinoma (2021) 8, 1537-1563 DOI: 10.2147/JHC.S334935
AI Summary: In this study, OriGene products Mouse anti-human LFABP (L2B10, AM26273PU-N) and Rabbit anti-human CD133 (EMK08, TA350943) were used as key antibodies to identify cellular markers, aiding in the reassessment of the cellular origins of primary epithelial tumors of the liver.
Snippet: … Rockville, MA, USA AM26273PU-N Rabbit anti-human CD133 1:100 EMK08 OriGene Tech. Rockville, MA, USA TA350943 Main Lineage Relationship and Molecular Phenotypes of Pare;Mouse anti-human LFABP 1:100 L2B10 OriGene Tech. Rockville, MA, USA AM26273PU-N
FigureFigureFigure
IHC
Showing 1-1 of 1 papers.
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