BPV-1 Protein E2 (310-410) Mouse Monoclonal Antibody [Clone ID: 3H5]
Specifications
| Product Data | |
| Clone Name | 3H5 |
|---|---|
| Application | ELISA, IF |
| Recommended Dilution | Immunoflourescence. ELISA. This is a conformational antibody and does not work in Western blot analysis or in other denaturative conditions. |
| Reactivity | Bovine |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Specificity | This antibody detects Bovine Papillomavirus E2- protein, mapped to amino acids 310-410. |
| Buffer | PBS with 50% glycerol State: Aff - Purified State: Liquid Ig fraction |
| Concentration | lot specific |
| Purification | Protein A affinity chromatography |
| Conjugation | Unconjugated |
| Storage | Upon receipt, store (in aliquots) at -20 to -70 °C. Avoid repeated freezing and thawing. |
| Stability | Shelf life: One year from despatch. |
| Shipping | Blue Ice |
| Database Link | |
| Background | The bovine papilloma virus E2 protein is the master regulator of papillomavirus replication and transcription. Binds to the E2RE response element (5'-ACCNNNNNNGGT-3') present in multiple copies in the regulatory region. Can either activate or repress transcription depending on E2RE's position with regards to proximal promoter elements. Repression occurs by sterically hindering the assembly of the transcription initiation complex. The E1-E2 complex binds to the origin of DNA replication. |
| Synonyms | BPV1 Regulatory protein E2 |
| Reference Data | |
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