BRG1 (SMARCA4) (C-term) Mouse Monoclonal Antibody [Clone ID: BRG-01]
$385.00
2 Weeks*
Specifications
| Product Data | |
| Clone Name | BRG-01 |
|---|---|
| Application | IHC, WB |
| Recommended Dilution | Western blot: 10 μg/ml Positive control: HEK293 cells. This clone has been described to work in Immunohistochemistry on Paraffin Sections. |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG2a |
| Clonality | Monoclonal |
| Immunogen | Bacterially produced GST-fused protein representing 242 C-terminal amino acids of human Brg1 |
| Specificity | The antibody BRG-01 recognizes an epitope within C-terminal part of Human Brg1, a 205 kDa catalytic subunit of SWI2/SNF2-family chromatin-remodeling complexes. |
| Buffer | PBS, pH~7.4 State: Aff - Purified State: Liquid purified Ig fraction (> 95% pure by SDS-PAGE) Preservative: 15 mM Sodium Azide |
| Concentration | lot specific |
| Purification | Affinity Chromatography on Protein A |
| Conjugation | Unconjugated |
| Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 |
| Database Link | |
| Background | Brg1 (Brahma-related gene 1) is an ATPase subunit of SWI2/SNF2-like chromatin-remodeling complexes that enable access of regulatory and effector proteins in transcription, DNA repair and DNA replication. Although Brg1-containing complexes are not essential for general cell survival, they participate in transcriptional regulation of several hundred genes including those involved in interferon and stress response, immune cells differentiation, neurogenesis, cell cycle etc. and is absolutely necessary for mouse embryogenesis. Brg1 is also involved in cell growth arrest, senescence and tumour supression. |
| Synonyms | SNF2B, SNF2L4, SNF2-beta, BRG-1 protein, Brahma protein homolog 1 |
| Reference Data | |
| Protein Categories | ADC Targets, Growth Factors, Intracellular Proteins |
| Protein Families | Druggable Genome, Transcription Factors |
Reviews
Documents
| Product Manuals |
| FAQs |
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Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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