SRC Mouse Monoclonal Antibody [Clone ID: 17AT28]
Specifications
| Product Data | |
| Clone Name | 17AT28 |
|---|---|
| Application | IF, WB |
| Recommended Dilution | WB:1/500-1000, IF:1/10-50 |
| Reactivity | Human, Mouse |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | This antibody is generated from mouse immunized with a recombinant protein of full length human SRC. |
| Specificity | This Src antibody is generated from mouse immunized with a recombinant protein of full length human SRC. |
| Buffer | PBS containing 0.09% (W/V) Sodium Azide as preservative. State: Purified State: Liquid purified Ig fraction. |
| Concentration | lot specific |
| Purification | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS. |
| Conjugation | Unconjugated |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Predicted Protein Size | 59.8 kDa |
| Gene Name | SRC proto-oncogene, non-receptor tyrosine kinase |
| Database Link | |
| Background | This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. |
| Synonyms | c-Src, pp60c-src |
| Reference Data | |
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