IL32 (1-131) Mouse Monoclonal Antibody [Clone ID: AT2F9]
Specifications
| Product Data | |
| Clone Name | AT2F9 |
|---|---|
| Application | ELISA, ICC, WB |
| Recommended Dilution | ELISA. Western blot (1:500 - 1:1000). Immnocytochemistry / Immunoflourescence. |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1, kappa |
| Clonality | Monoclonal |
| Immunogen | Recombinant human IL32 (1-131aa) purified from E. coli |
| Specificity | The antibody recognizes human IL-32 at aa1-131. Other species not tested. |
| Buffer | Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol |
| Concentration | 1mg/ml (determined by BCA assay) |
| Purification | By protein-A affinity chromatography |
| Conjugation | Unconjugated |
| Storage | Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | interleukin 32 |
| Database Link | |
| Background | The gene encoding IL32 is located on human chromosome 16p13. 3 and is organized into eight exons. IL32 is mainly expressed in natural killer cells, T cells, epithelial cells, and blood monocytes. It can induce the proinflammatory cytokines TNFalpha and IL1beta in murine peritoneal macrophages as well as in phorbol ester-differentiated human THP1 cells. In the inflamed lesions of chronic pancreas, the ductal expression of IL32 was markedly increased. Pancreatic duct cells are the local source of IL32, and IL32 may play an important role in inflammatory responses and pancreatic cancer growth. Recently, a synergism between IL32 and other well characterized players in innate immunity has been documented. |
| Synonyms | Interleukin 32, Natural killer cells protein 4, Natural killer cell transcript 4, NK4, Tumor necrosis factor alpha-inducing factor, TAIF, TAIFb, TAIFd |
| Reference Data | |
| Protein Categories | Cytokines, Intracellular Proteins, Secreated Proteins |
| Protein Families | Secreted Protein |
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