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Factor VII (F7) Mouse Monoclonal Antibody [Clone ID: RFFVII/2]

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SKU
AM09326PU-N
Factor VII (F7) mouse monoclonal antibody, clone RFFVII/2, Aff - Purified
Size:
500 ug
Conjugation:
Unconjugated
  $815.00
5 Days*
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View other "Factor VII or NP_000122" antibodies

Specifications
Specifications
Product Data
Clone Name RFFVII/2
Application ELISA, R, WB
Recommended Dilution ELISA.
Clone RFFVII/2 may be used as a Capture antibody in Immunoassay for Factor VII in combination with clone RFFVII/1 as a Detection reagent.
Radioimmunoassays.
Western blotting: This Factor VII antibody binds to a conformational epitope and will not bind to reduced Factor VI.
Reactivity Human
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Purified Factor VII.
Specificity Recognizes Human Factor VII antigen. Other spcies not tested.
Buffer PBS, pH 7.4 containing 0.09% Sodium Azide as preservative
State: Aff - Purified
State: Liquid purified IgG fraction from Tissue Culture Supernatant
Concentration lot specific
Purification Affinity Chromatography on Protein G
Conjugation Unconjugated
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Gene Name coagulation factor VII
Database Link
Background Factor VII is a 50kDa multi-domain, single chain plasma glycoprotein synthesised in the liver and having anormal circulating concentration of between 400 and 600 µg/L. It is essential for blood coagulation. Factor VII is converted to the active, two chain, serine protease Factor VIIa through cleavage by thrombin, factor Xa, factor IXa or factor XIIa. Factor VIIa converts factor X to factor Xa, which in turn converts Prothrombin to Thrombin.
Synonyms Proconvertin, SPCA
Reference Data
Protein Categories Cardiovascular diseases, Enzyme: Peptidases, Growth Factors, Secreated Proteins
Protein Families Druggable Genome, Protease
Protein Pathways Complement and coagulation cascades
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Documents
Resources

file-alt Citations

A machine learning approach to integrate big data for precision medicine in acute myeloid leukemia
Lee, Celik, Logsdon et al
Nat Commun (2018) 9 (1), 42 DOI: 10.1038/s41467-017-02465-5
AI Summary: OriGene products, including the SMARCA4 cDNA plasmid, TurboFectin 8.0 transfection reagent, and a mouse monoclonal anti-SMARCA4 antibody, were used to generate and validate SMARCA4-overexpressing cell lines, enabling the study of SMARCA4’s role in drug sensitivity in acute myeloid leukemia.
Snippet: The plasmid containing the cDNA for SMARCA4 and the TurboFectin 8.0 reagent were obtained from Origene Technologies, Rockville, MD. …SMARCA4 protein expression was analyzed using a mouse monoclonal antibody (clone 6D7-F7-B6) against SMARCA4 (Origene Technologies, Rockville, MD) to stain western blots prepared by transfer from 4 to 20% sodium dodecyl sulfate polyacrylamide gels run on whole-cell lysates
FigureFigureFigure
WB
Showing 1-1 of 1 papers.
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