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CD41-CD61 Complex Mouse Monoclonal Antibody [Clone ID: 237]

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SKU
AM09275PU-N
CD41-CD61 Complex mouse monoclonal antibody, clone 237, Aff - Purified
Size:
500 ug
Conjugation:
Unconjugated
  $795.00
2 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Clone Name 237
Application ELISA, WB
Recommended Dilution This GPIIb/IIIa antibody is Suitable for use in ELISA and Western Blot.
Use of this Monoclonal antibody at a concentration of 10-20 µg/ml (culture supernatants) will allow visualization of NP 40 solubilized human normal platelets.
The titer of purified ascites was determined by ELISA coated with 100 µl of 1x108 washed platelets.
Reactivity Human
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen 10e9 Human platelets suspension.
The supernatant fluid from positive clones was screened by ELISA coated with washed platelets.
Specificity Human platelet membrane glycoproteins IIb/IIIa (GP IIb/IIIa).
Under reducing conditions, this antibody will bind against the Human platelet membrane glycoproteins IIb/IIIa complex, which have a molecular weights of ~130,000 (IIb) and 115,000 (IIIa).
Buffer 0.01M PBS, pH 7.2 without preservatives.
State: Aff - Purified
State: Lyophilized purified IgG fraction.
Reconstitution Method Restore with Double distillated water to adjust the final concentration to 1.0 mg/ml.
Purification Affinity Chromatography on Protein G.
Conjugation Unconjugated
Storage Store the antibody at -20°C.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Shipping Ambient
Background The integrins are a family of more than 23 heterodimeric transmembrane proteins that mediate cell-cell adhesions as well as cell-substratum adhesions and signal transduction processes. Integrins are heterodimers consisting of noncovalently associated alpha and beta subunits. CD61 non-covalently associates with CD41 (alpha Ilb integrin) and is expressed by megakaryocytes and platelets. The CD61/CD41 complex acts as a receptor for such adhesive ligands as fibronectin, fibrinogen and von Willebrand factor during platelet stimulation.
Synonyms GPIIb-IIIa, ITGA2B, GP2B, ITGAB, Platelet membrane glycoprotein IIb, GPalpha IIb, GPIIb, GP3A, CD41, CD61, Integrin alpha-IIb, Integrin beta-3, ITGB3
Reference Data
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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