GM CSF (CSF2) Mouse Monoclonal Antibody [Clone ID: 120]
Specifications
| Product Data | |
| Clone Name | 120 |
|---|---|
| Application | ELISA, WB |
| Recommended Dilution | ELISA. Western Blot. |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Purified recombinant human GM-CSF. |
| Specificity | This monoclonal antibody reacts with natural and recombinant human GM-CSF. Does not show any cross reaction with other human Cytokines or Growth Factors tested such as M-CSF, G-CSFR, IL-8, IL-16, IL1-beta, TGFbeta-1 and TNF-alpha. |
| Buffer | 0.01M PBS, pH 7.2 without preservatives. State: Purified State: Lyophilized purified IgG fraction. |
| Reconstitution Method | Restore with double distillated water to adjust the final concentration to 1.00 mg/ml |
| Concentration | lot specific |
| Purification | Affinity Chromatography on Protein G. |
| Conjugation | Unconjugated |
| Storage | Store the antibody at -20°C. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Ambient |
| Gene Name | colony stimulating factor 2 |
| Database Link | |
| Background | The cytokine GM-CSF stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. Used in myeloid reconstitution following bone marrow transplant, bone marrow transplant engraftment failure or delay, mobilization and following transplantation of autologous peripheral blood progenitor cells, and following induction chemotherapy in older adults with acute myelogenous leukemia. |
| Synonyms | CSF2, GMCSF, Sargramostim, Molgramostin |
| Reference Data | |
| Protein Categories | Cytokines, Growth Factors, Secreated Proteins |
| Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein |
| Protein Pathways | Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, Hematopoietic cell lineage, Jak-STAT signaling pathway, Natural killer cell mediated cytotoxicity, T cell receptor signaling pathway |
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