STEAP1 Mouse Monoclonal Antibody [Clone ID: J2D2]
Specifications
| Product Data | |
| Clone Name | J2D2 |
|---|---|
| Application | ELISA, ICC, IHC, WB |
| Recommended Dilution | ELISA. Western blot: 1/1000-1/2000. Immunofluorescence: 1/100-1/300. Immunohistochemsitry on Praffin Sections: 1/50-1/100. |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG2b, kappa |
| Clonality | Monoclonal |
| Immunogen | Recombinant human STEAP1 (1-70aa) purified from E. coli |
| Specificity | The antibody recognizes STEAP1. |
| Buffer | Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol |
| Concentration | 1mg/ml (determined by BCA assay) |
| Purification | By protein-G affinity chromatography |
| Conjugation | Unconjugated |
| Storage | Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | six transmembrane epithelial antigen of the prostate 1 |
| Database Link | |
| Background | Six-transmembrane epithelial antigen of the prostate (STEAP) is expressed predominantly in human prostate tissue and in other common malignancies including prostate, bladder, colon, and ovarian carcinomas, and in Ewings sarcoma, suggesting that it could function as an almost universal tumor antigen. Immunohistochemical analysis indicated STEAP-1 localization at cell-cell junctions of the secretory epithelium of prostate and prostate cancer cells. The favorable expression profiling of STEAP-1 in normal and cancer tissues suggested its potential use as a target for immunotherapy. |
| Synonyms | six transmembrane epithelial antigen of the prostate 1, six transmembrane epithelial antigen of the prostate, PRSS24 |
| Reference Data | |
| Protein Categories | ADC Targets, Membrane Proteins |
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