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MHC Class II I-Ab Rat Monoclonal Antibody [Clone ID: NIMR-4]

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SKU
AM08075LE-N
MHC Class II I-Ab rat monoclonal antibody, clone NIMR-4, Low Endotoxin
Size:
500 ug
Conjugation:
Unconjugated
  $660.00
3 Days*
Bulk/Customize

View other "H2-Eb1" antibodies

Specifications
Specifications
Product Data
Clone Name NIMR-4
Application FC, FN
Recommended Dilution Flow Cytometry.
Complement-dependent Cytotoxicity Assays.
Reactivity Mouse
Antibody Host Rat
Isotype IgG2b
Clonality Monoclonal
Specificity Specific to MHC Class II molecules.
This antibody reacts specifically with a non-polymorphic I-A-encoded epitope on MHC Class II antigens. Class II antigens are predominantly expressed on antigen-presenting cells including B lymphocytes, macrophages, dendritic cells and certain epithelial cells.
Buffer PBS without preservatives.
State: Low Endotoxin
State: Liquid purified Ig fraction.
Concentration lot specific
Conjugation Unconjugated
Storage Store the antibody undiluted (in aliquots) at -20°C.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Database Link
Background MHC Class II antigens are heterodimers consisting of one alpha chain(31-34kD) and one beta chain (26-29kD). The family of monoclonal antibodies (ER-TR 3, ER-TR 2, ER-TR 1) detect MHC class II antigens encoded by the murine Ia region of the H-2 complex, corresponding to the human HLA-DR region. MHC Class II antigens are a valuable tool for studying T helper cell interaction with class II positive antigen presenting cells (dendritic cells, B cells, macrophages) and offer new possibilities for studying the development of T helper cells since these antibodies also stain stromal cells in the thymus. MHC Class II antigens are also inducible on a number of other cells (endothelium and epithelial cells) by interferon gamma.
Synonyms H2-Eb1, H-2 class II histocompatibility antigen I-A beta chain
Reference Data
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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