RAP1A Mouse Monoclonal Antibody [Clone ID: 5F8G2]
Specifications
| Product Data | |
| Clone Name | 5F8G2 |
|---|---|
| Application | ELISA, FC, WB |
| Recommended Dilution | ELISA: 1/10000. Western Blot: 1/500 - 1/2000. Flow Cytometry: 1/200 - 1/400. |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Purified recombinant fragment of Human RAP1A expressed in E. Coli. |
| Specificity | Recognizes RAP1A |
| Buffer | PBS State: Purified State: Liquid purified antibody Stabilizer: 0.5% protein stabilizer Preservative: 0.05% Sodium Azide |
| Concentration | lot specific |
| Conjugation | Unconjugated |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Predicted Protein Size | 43.2 kDa |
| Gene Name | RAP1A, member of RAS oncogene family |
| Database Link | |
| Background | The product of this gene belongs to the family of RAS-related proteins. These proteins share approximately 50% amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between RAP proteins and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins. The product of this gene counteracts the mitogenic function of RAS because it can interact with RAS GAPs and RAF in a competitive manner. Two transcript variants encoding the same protein have been identified for this gene. |
| Synonyms | RAP-1A, C21KG, KREV1, KREV-1 |
| Reference Data | |
| Protein Categories | Growth Factors, Intracellular Proteins |
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