NQO1 Mouse Monoclonal Antibody [Clone ID: 1A11]
Specifications
| Product Data | |
| Clone Name | 1A11 |
|---|---|
| Application | ELISA, FC, WB |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Flow cytometry: 1/200 - 1/400. ELISA: 1/10000. |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Purified recombinant fragment of human NQO1 expressed in E. Coli. |
| Specificity | This antibody reacts to NQO1. |
| Buffer | State: Ascites State: Ascitic fluid containing 0.03% sodium azide. |
| Conjugation | Unconjugated |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Predicted Protein Size | 31 kDa |
| Gene Name | NAD(P)H quinone dehydrogenase 1 |
| Database Link | |
| Background | This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. |
| Synonyms | DIA4, NMOR1 |
| Reference Data | |
| Protein Categories | Intracellular Proteins |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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