SRC Mouse Monoclonal Antibody [Clone ID: 1F11]
Specifications
| Product Data | |
| Clone Name | 1F11 |
|---|---|
| Application | ELISA, FC, IHC, WB |
| Recommended Dilution | ELISA: 1/10000. Flow Cytometry: 1/200-1/400. Western Blot: 1/500-1/2000. Immunohistochemistry on Paraffin Sections: 1/200-1/1000. |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Purified recombinant fragment of Human SRC expressed in E. Coli. |
| Specificity | This antibody recognizes Human SRC. Other species not tested. |
| Buffer | State: Ascites State: Liquid Ascitic fluid Preservative: 0.03% Sodium Azide |
| Conjugation | Unconjugated |
| Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Predicted Protein Size | 60 kDa |
| Gene Name | SRC proto-oncogene, non-receptor tyrosine kinase |
| Database Link | |
| Background | This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. |
| Synonyms | c-Src, pp60c-src |
| Reference Data | |
| Protein Categories | Cardiovascular diseases, Cytokines, Enzyme: Kinases, Growth Factors, Intracellular Proteins |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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