TAB2 Mouse Monoclonal Antibody [Clone ID: 3B5]

SKU AM06537SU-N

TAB2 mouse monoclonal antibody, clone 3B5, Ascites

Product Data

• Clone Name: 3B5
• Application: ELISA, FC, WB
• Recommended Dilution: ELISA: 1/10000.; Western Blot: 1/500 - 1/2000.; Flow Cytometry: 1/200 - 1/400.
• Reactivity: Human
• Antibody Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Purified recombinant fragment of Human TAB2 expressed in E. Coli.
• Specificity: Recognizes TAB2 / MAP3K7IP2
• Buffer: State: Ascites; State: Ascitic fluid containing 0.03% Sodium Azide.
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. ; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Predicted Protein Size: 80 kDa
• Gene Name: TGF-beta activated kinase 1/MAP3K7 binding protein 2
• Database Link:
  Q9NYJ8
• Background: The protein encoded by this gene is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, thus serves as an adaptor linking MAP3K7 and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts.
• Synonyms: TAK1-binding protein 2, Tab-2, Mitogen-activated protein kinase kinase kinase 7-interacting protein 2

Reference Data