RTN3 Mouse Monoclonal Antibody [Clone ID: 1E11]

CAT#: AM06407SU-N

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RTN3 mouse monoclonal antibody, clone 1E11, Ascites

USD 486.00

2 Weeks

    • 100 ul

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Product Data
Clone Name 1E11
Applications IF
Recommended Dilution ELISA: 1/10000.
Immunofluorescence: 1/200 - 1/1000.
Reactivities Human
Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Purified recombinant fragment of RTN3 expressed in E. Coli.
Specificity Recognizes Reticulon 3 (RTN3).
Formulation State: Ascites
State: Ascitic fluid containing 0.03% Sodium Azide.
Conjugation Unconjugated

Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.

Stability Shelf life: one year from despatch.

Predicted Protein Size 113 kDa
Background The reticulons are a group of highly conserved genes with preferential expression in neuroendocrine tissues. RTN3 may be involved in membrane trafficking in the early secretory pathway. Inhibits BACE1 activity and amyloid precursor protein processing. May induce caspase-8 cascade and apoptosis. May favor BCL2 translocation to the mitochondria upon endoplasmic reticulum stress. In case of enteroviruses infection, RTN3 may be involved in the viral replication or pathogenesis. There are 5 isoforms.
Synonyms ASYIP, NSPL2, NSPLII, NSP-like protein 2
Reference Data
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