FABP4 Mouse Monoclonal Antibody [Clone ID: 9B8D]
Specifications
| Product Data | |
| Clone Name | 9B8D |
|---|---|
| Application | ELISA, WB |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Purified recombinant fragment of FABP4 expressed in E. Coli. |
| Specificity | This antibody reacts to FABP4. |
| Buffer | State: Ascites State: Ascitic fluid containing 0.03% sodium azide. |
| Conjugation | Unconjugated |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Predicted Protein Size | 14 kDa |
| Gene Name | fatty acid binding protein 4 |
| Database Link | |
| Background | Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long chain fatty acids, their coenzymes and other hydrophobic ligands and small molecules in the cytoplasm. It is thought that the role of these proteins includes fatty acid uptake, intracellular lipid transport and metabolism. FABP4 encodes the fatty acid binding protein found in adipocytes. FABP4 knockout mice fed a high-fat and high-calorie diet become obese but develop neither insulin resistance nor diabetes, suggesting that this protein might be a link between obesity and insulin resistance and diabetes A related study in humans indicated a similar pattern, suggesting that FABP4 may be a potential therapeutic target in the treatment of these disorders. |
| Synonyms | A-FABP, Adipocyte lipid-binding protein, Fatty acid-binding protein 4 |
| Reference Data | |
| Protein Categories | Intracellular Proteins |
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