RTN3 Mouse Monoclonal Antibody [Clone ID: 10A8]

SKU AM06348SU-N

RTN3 mouse monoclonal antibody, clone 10A8, Ascites

Product Data

• Clone Name: 10A8
• Application: ELISA, IHC
• Recommended Dilution: ELISA: 1/10000.; Immunohistochemistry on Paraffin Sections: 1/200 - 1/1000.
• Reactivity: Human
• Antibody Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Purified recombinant fragment of RTN3 expressed in E. Coli.
• Specificity: Recognizes RTN3 (Reticulon 3)
• Buffer: State: Ascites; State: Ascitic fluid containing 0.03% Sodium Azide.
• Conjugation: Unconjugated
• Storage:

  Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Shipping: Blue Ice
• Predicted Protein Size: 113 kDa
• Gene Name: reticulon 3
• Database Link:
  O95197
• Background: The reticulons are a group of highly conserved genes with preferential expression in neuroendocrine tissues. RTN3 may be involved in membrane trafficking in the early secretory pathway. Inhibits BACE1 activity and amyloid precursor protein processing. May induce caspase-8 cascade and apoptosis. May favor BCL2 translocation to the mitochondria upon endoplasmic reticulum stress. In case of enteroviruses infection, RTN3 may be involved in the viral replication or pathogenesis. There are 5 isoforms.
• Synonyms: ASYIP, NSPL2, NSPLII, NSP-like protein 2

Reference Data