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MPS1 (RPS27) Mouse Monoclonal Antibody [Clone ID: 4A12]

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SKU
AM06342SU-N
MPS1 (RPS27) mouse monoclonal antibody, clone 4A12, Ascites
Size:
100 ul
Conjugation:
Unconjugated
  $580.00
2 Weeks*
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View other "RPS27 or NP_001021.1" antibodies

Specifications
Specifications
Product Data
Clone Name 4A12
Application ELISA, IHC
Recommended Dilution ELISA: 1/10000.
Immunohistochemistry on Paraffin Sections: 1/200 - 1/1000.
Reactivity Human
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Purified recombinant fragment of MPS1 expressed in E. Coli.
Specificity Recognizes MPS1, also known as RPS27.
Buffer State: Ascites
State: Ascitic fluid containing 0.03% Sodium Azide.
Conjugation Unconjugated
Storage

Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Predicted Protein Size 95 kDa
Gene Name ribosomal protein S27
Database Link
Background MPS1, also known as RPS27. It is a ribosomal protein. Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. MPS1 is a component of the 40S subunit. The protein belongs to the S27E family of ribosomal proteins. It contains a C4-type zinc finger domain that can bind to zinc. The encoded protein has been shown to be able to bind to nucleic acid. It is located in the cytoplasm as a ribosomal component, but it has also been detected in the nucleus. Studies in rat indicate that ribosomal protein S27 is located near ribosomal protein S18 in the 40S subunit and is covalently linked to translation initiation factor eIF3. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
Synonyms MPS1, Metallopan-stimulin 1, MPS-1, 40S ribosomal protein S27
Reference Data
Protein Categories Cardiovascular diseases, Intracellular Proteins
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Documents
Resources

file-alt Citations

Ablation of the spindle assembly checkpoint by a compound targeting Mps1
Schmidt, Budirahardja, Klompmaker et al
EMBO Rep (2005) 6 (9), 866-72 DOI: 10.1038/sj.embor.7400483
Cited by 115
AI Summary: OriGene products contributed to this study by providing the human Mps1 cDNA (OriGene, SC119008) used for expression experiments investigating the role of Mps1 in spindle assembly checkpoint function.
Showing 1-1 of 1 papers.
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