CD18 (ITGB2) Mouse Monoclonal Antibody [Clone ID: 10E12]
$580.00
2 Weeks*
Specifications
| Product Data | |
| Clone Name | 10E12 |
|---|---|
| Application | ELISA, IF |
| Recommended Dilution | ELISA: 1/10000. Immunofluorescence: 1/200 - 1/1000. |
| Reactivity | Human, Mouse |
| Antibody Host | Mouse |
| Isotype | IgG2b |
| Clonality | Monoclonal |
| Immunogen | Purified recombinant fragment of CD18 expressed in E. Coli. |
| Specificity | Recognizes CD18 also known as ITGB2 (integrin beta chain beta 2). |
| Buffer | State: Ascites State: Ascitic fluid containing 0.03% Sodium Azide. |
| Conjugation | Unconjugated |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Predicted Protein Size | 85 kDa |
| Gene Name | integrin subunit beta 2 |
| Database Link | |
| Background | CD18, also known as ITGB2 (integrin beta chain beta 2). Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. CD18 is expressed by most leucocytes. Defects in this gene are the cause of leukocyte adhesion deficiency type I (LAD1). Two transcript variants encoding the same protein have been identified for this gene. |
| Synonyms | Integrin beta-2, MFI7 |
| Reference Data | |
| Protein Categories | CD Markers, Immune system diseases, Intracellular Proteins, Membrane Proteins |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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