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FGFR4 Mouse Monoclonal Antibody [Clone ID: 4H2B10B2]

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SKU
AM06181SU-N
FGFR4 mouse monoclonal antibody, clone 4H2B10B2, Ascites
Size:
100 ul
Conjugation:
Unconjugated
  $580.00
2 Weeks*
Bulk/Customize

View other "FGFR4 or NP_002002.3" antibodies

Specifications
Specifications
Product Data
Clone Name 4H2B10B2
Application IHC, WB
Recommended Dilution ELISA: 1/10000.
Western Bloting: 1/500 - 1/2000.
Immunohistochemistry on Paraffin Sections: 1/200 - 1/1000.
Reactivity Human
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Purified recombinant fragment of FGFR4 expressed in E. Coli.
Specificity Recognizes CD334 / FGFR4
Buffer State: Ascites
State: Ascitic fluid containing 0.03% Sodium Azide.
Conjugation Unconjugated
Storage

Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Predicted Protein Size 88 kDa
Gene Name fibroblast growth factor receptor 4
Database Link
Background FGFR4 (fibroblast growth factor receptor 4) is part of a family of fibroblast growth factor receptors that mediate the biological functions of specific growth factors. There are four members of the FGF receptor family: FGFR-1 (flg), FGFR-2 (bek, KGFR), FGFR-3 and FGFR-4. Each receptor contains an extracellular ligand binding domain, a transmembrane domain and a cytoplasmic kinase domain. Following ligand binding and dimerization, the receptors are phosphorylated at specific tyrosine residues. These receptor proteins play a role in important processes such as cell division, regulating cell growth and maturation, formation of blood vessels, wound healing, and embryo development. Although specific functions of FGFR4 remain unclear, studies indicate that the gene is involved in muscle development and the maturation of bone cells in the skull. FGFR4 may also play a role in the development and maintenance of specialized cells (called foveal cones) in the light-sensitive layer (the retina) at the back of the eye.
Synonyms FGFR-4, JTK2, TKF
Reference Data
Protein Categories CD Markers, Enzyme: Kinases, Growth Factors, Intracellular Proteins, Membrane Proteins
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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