CD51 / ITGAV Rat Monoclonal Antibody [Clone ID: RMV-7]
$645.00
5 Days*
Specifications
| Product Data | |
| Clone Name | RMV-7 |
|---|---|
| Application | FC, IHC, IP |
| Recommended Dilution | Flow Cytometry: 1/25 - 1/100. Immunohistochemistry on frozen sections: 1/25 - 1/100. Immunoprecipitation. |
| Reactivity | Mouse |
| Antibody Host | Rat |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | cultured LAK cells from Balb/c mice. |
| Specificity | This antibody recognises CD51. The RMV-7 antibody has been reported to block binding of CD51 to vitronectin, fibronectin, and CD31 in some cell types, as well as blocking LAK cell cytotoxicity. |
| Buffer | Phosphate buffered saline pH7.4 containing 0,09% sodium azide State: Purified State: Liquid purified IgG |
| Concentration | lot specific |
| Purification | Affinity chromatography on Protein G |
| Conjugation | Unconjugated |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | integrin alpha V |
| Database Link | |
| Background | CD51 is a 140 kD alpha subunit of the vitronectin receptor, which is otherwise known as the intergrin alpha v chain. CD51 can form heterodimers at the cell surface with a variety of beta integrins including CD29 and CD61. Heterodimers of CD51/CD61 functions as a receptor for vitronectin, and a wide array of RGD-containing proteins including fibronectin, fibrinogen, von Willebrand factor, laminin, thrombospondin and osteopontin. CD51/CD61 is primarily expressed on myeloid cells and activated T-cells. Alpha-V integrins may play a role in embryo implantation, angiogenesis and wound healing. |
| Synonyms | Integrin alpha-V, MSK8, VNRA, Vitronectin receptor subunit alpha |
| Reference Data | |
| Protein Categories | ADC Targets, CD Markers, Chemokines, Growth Factors, Intracellular Proteins, Membrane Proteins |
Reviews
Documents
| Product Manuals |
| FAQs |
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Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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