Vcam1 Rat Monoclonal Antibody [Clone ID: MVCAM A (429)]
Specifications
| Product Data | |
| Clone Name | MVCAM A (429) |
|---|---|
| Application | FC, IHC |
| Recommended Dilution | Flow Cytometry: Use 10 µl of 1/10-1/50 diluted antibody to label 106 cells in 100 µl. Immunohistochemistry on Frozen Sections. |
| Reactivity | Mouse |
| Antibody Host | Rat |
| Isotype | IgG2a |
| Clonality | Monoclonal |
| Immunogen | Stromal cell line PA6 |
| Specificity | This antibody recognizes vascular adhesion molecule 1 (VCAM-1), a cell surface glycoprotein that is also known as CD106. Clone MVCAM A (429) is reported to partially block VCAM-1 mediated functions (See Kinashi, T. and Springer, T.A. for details). |
| Buffer | PBS State: Purified State: Liquid purified IgG fraction Preservative: 0.09% Sodium Azide |
| Concentration | lot specific |
| Purification | Affinity Chromatography on Protein G |
| Conjugation | Unconjugated |
| Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | vascular cell adhesion molecule 1 |
| Database Link | |
| Background | CD106 is expressed predominantly on endothelial cells and expression is up-regulated during inflammation. The ligand for CD106 is the alpha 4 subunit (CD49d) of the integrin VLA-4 (CD49d/CD29). |
| Synonyms | V-CAM 1, INCAM-100, L1CAM, VCAM-1 |
| Reference Data | |
| Protein Categories | CD Markers, Cytokines, Growth Factors, Membrane Proteins |
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