ARAP1 Mouse Monoclonal Antibody [Clone ID: ARAP1-2]

SKU
AM03037PU-N
ARAP1 mouse monoclonal antibody, clone ARAP1-2, Aff - Purified
  $380.00
2 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Clone Name ARAP1-2
Application IF, IP, WB
Recommended Dilution Suitable for Western Blotting (2 μg/ml).
Immunoprecipitation.
Immunocytochemistry.
Reactivity Human
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen His6-tagged protein corresponding to amino acids 1190-1450 of human ARAP1
Specificity The antibody ARAP1-2 reacts with C-terminal part of ARAP1, a 160 kDa adaptor protein.
Buffer PBS, pH 7.4 with 15 mM sodium azide as preservative.
State: Aff - Purified
State: Liquid purified Ig fraction (> 95% pure by SDS-PAGE)
Concentration lot specific
Purification Protein A affinity chromatography
Conjugation Unconjugated
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid freeze/thaw cycles.
Stability Shelf life: One year from despatch.
Shipping Blue Ice
Gene Name ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
Database Link
Background ARAP1 (angiotensin II type 1 receptor-associated protein) is an adaptor protein with ArfGAP and RhoGAP activities, containing five PH domains and ankyrin repeate. This adaptor seems to serve as a link between phosphoinositide- Arf-, and Rho-mediated cell signaling. ARAP1 supports the plasma membrane recycling of angiotensin II type 1 receptor (AT1) and is important also for cell-specific trafficking of pro-death receptor TRAIL-R1 (DR4) to the plasma membrane, thus promoting the TRAIL-induced apoptosis in certain cell types. ARAP1 also affects cell spreading.
Synonyms KIAA0782, Centaurin-delta-2
Reference Data
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.