Osteocalcin (BGLAP) Mouse Monoclonal Antibody [Clone ID: 2H9F11F8]
Specifications
| Product Data | |
| Clone Name | 2H9F11F8 |
|---|---|
| Application | ELISA |
| Recommended Dilution | ELISA: Suitable for use in a Sandwich ELISA with AM01189PU-N, AM05457PU-N or AM05458PU-N. |
| Reactivity | Bovine, Human, Porcine, Rabbit, Rat |
| Antibody Host | Mouse |
| Isotype | IgG2a |
| Clonality | Monoclonal |
| Immunogen | Recombinant human osteocalcin GST fusion protein. |
| Specificity | This antibody recognizes intact human and bovine osteocalcin in a "2 site" assay and reacts with osteocalcin fragments corresponding to amino acids 15-31 and 20-43 of the native molecule. It does not recognize fragments representing amino acids 1-19 or 7-19. |
| Buffer | PBS containing 0.09% Sodium Azide State: Purified State: Liquid purified IgG fraction |
| Concentration | lot specific |
| Purification | Affinity Chromatography on Protein A |
| Conjugation | Unconjugated |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | bone gamma-carboxyglutamate protein |
| Database Link | |
| Background | Osteocalcin (Bone Gla Protein) is a 49 amino acid single chain vitamin K dependent protein (MW 5.8 kDa), made by osteoblasts that is a major component of the non-collagenous bone matrix. Serum osteocalcin is elevated in diseases characterized by increased bone turnover such as osteoporosis, hyperparathyroidism and Pagets disease, and low in conditions associated with low bone turnover such as hypoparathyroidism and growth hormone deficiency. |
| Synonyms | Bone Gla protein, BGLAP |
| Reference Data | |
| Protein Categories | Growth Factors, Secreated Proteins |
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