Angiotensinogen (AGT) Mouse Monoclonal Antibody [Clone ID: BGN/KA/4H]
Specifications
| Product Data | |
| Clone Name | BGN/KA/4H |
|---|---|
| Application | ELISA |
| Recommended Dilution | ELISA Does not react with angiotensin II, III or angiotensinogen in ELISA. |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG2a |
| Clonality | Monoclonal |
| Immunogen | HMW conjugate Synthetic peptide corresponding to amino acids 40-49 of the angiotensinogen precursor conjugated to HMW carrier protein. |
| Specificity | Reacts to Angiotensin I. |
| Buffer | PBS buffer, pH 7.2, 0.1% Sodium Azide State: Purified State: Liquid purified Ig |
| Concentration | lot specific |
| Purification | Protein A chromatography |
| Conjugation | Unconjugated |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | angiotensinogen |
| Database Link | |
| Background | Angiotensin-I is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. |
| Synonyms | Angiotensin-1, Angiotensin-I, AGT-1, AGT1 |
| Reference Data | |
| Protein Categories | Cytokines, Growth Factors, Membrane Proteins, Secreated Proteins |
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