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HIF-1 alpha (HIF1A) Goat Polyclonal Antibody

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SKU
AB0070-100
Goat Polyclonal Anti-HIF1a Antibody
Size:
300 ug
Conjugation:
Unconjugated
  $485.00
In Stock*
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View other "HIF-1 alpha or NM_001530" antibodies

Specifications
Specifications
Product Data
Application WB
Recommended Dilution WB 1:500-1:2,000
Reactivity Canine, Human, Mouse
Antibody Host Goat
Isotype IgG
Clonality Polyclonal
Immunogen Purified recombinant peptide derived from within residues 470 to 590 aa of human HIF1a produced in E. coli.
Buffer Polyclonal antibody supplied as a 100 µl (3 mg/ml) aliquot in PBS, 20% glycerol and 0.05% sodium azide.
Concentration 3mg/ml
Purification epitope affinity purified
Conjugation Unconjugated
Shipping Blue Ice
Gene Name hypoxia inducible factor 1 alpha subunit
Database Link
Background Hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
Synonyms bHLHe78; HIF-1alpha; HIF1; HIF1-ALPHA; MOP1; PASD8
Note Detects HIF1a in transfected cells and a band of approximately 120 kDa by Western blot in cell lysates.
Reference Data
Protein Categories Cancer: Head and Neck, Chemokines, Cytokines, Growth Factors, Intracellular Proteins, Transciption Factors
Protein Families Transcription Factors
Protein Pathways mTOR signaling pathway, Pathways in cancer, Renal cell carcinoma
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Documents
Resources

file-alt Citations

Hyperglycemia-induced degradation of HIF-1α contributes to impaired response of cardiomyocytes to hypoxia
Ramalho, Toscano, Pereira et al
Rev Port Cardiol (2017) 36 (5), 367-373 DOI: 10.1016/j.repc.2016.09.018
Cited by 18
AI Summary: In this study, OriGene’s mouse HIF-1α antibody (Cat# TA500145) was used for western blot analysis to assess HIF-1α protein levels in cardiomyocytes under various conditions, helping to elucidate the role of hyperglycemia-induced degradation of HIF-1α in impaired hypoxic response.
Showing 1-1 of 1 papers.
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