Human Neugrin (NGRN) activation kit by CRISPRa

SKU GA109750

NGRN CRISPRa kit - CRISPR gene activation of human neugrin, neurite outgrowth associated

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: NGRN
• Locus ID: 51335
• Components:

  GA109750G1, Neugrin gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA109750G2, Neugrin gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA109750G3, Neugrin gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001033088, NM_016645, NR_028052
• UniProt ID: Q9NPE2
• Synonyms: DSC92
• Summary: Plays an essential role in mitochondrial ribosome biogenesis. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation of core subunits of the oxidative phosphorylation system.[UniProtKB/Swiss-Prot Function]