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AAV Antibodies
Product efficacy and quality are crucial factors in AAV gene therapy; OriGene AAV antibodies help ensure high quality and quantity of viral expression levels. We offer:
- AAV capsid protein antibodies- that react with denatured AAV capsid proteins VP1, VP2 and VP3
- AAV replicase antibodies- that react with four regulatory proteins: Rep78, Rep68, Rep 52, and Rep40
- AAV particle antibodies- that recognize conformational epitopes of the viral capsid proteins.
AAV Antibodies
| Serotype | Description | Antibody Type | Application |
|---|---|---|---|
| AAV | AAV Rabbit & Mouse Monoclonal Antibodies | Capsid Antibody | WB |
| AAV2 | AAV2 (Rep78, 68, 52, 40) Mouse Monoclonal Antibody | Replicase Antibody | WB |
| AAV2 | AAV2 Rabbit Monoclonal Antibody | Capsid Antibody | WB |
| AAV5 | AAV5 Rabbit Monoclonal Antibody | Capsid Antibody | WB |
| AAV8 | AAV8 Rabbit Monoclonal Antibody | Capsid Antibody | WB |
| AAV9 | AAV9 Rabbit Monoclonal Antibody | Capsid Antibody | WB |
Advantages of OriGene Antibodies
- High Specificity - in viral protein detection by WB
- High Sensitivity - to detect different serotypes
- Consistent Results- with recombinant AAV antibodies
- Synergy- with our AAV ORF and Packaging services
Capsid Protein & Replicase Antibodies
Capsid Protein Antibodies
OriGene's antibodies against AAV capsid proteins identify linear epitopes within the VP1, VP2, and VP3 viral capsid proteins. The notable sequence similarity among AAV capsid proteins facilitates straightforward protein detection across different serotypes.
Replicase Antibodies
Replicase antibodies selectively target regulatory proteins (Rep78, Rep68, Rep52, Rep40) encoded by the rep-gene, which is pivotal for AAV genome replication and packaging. These antibodies enable:
- Analysis: Monitoring AAV Rep gene expression.
- Monitoring: Assessing AAV infection status and DNA replication dynamics.
- Safety Assurance: Detecting viral protein contamination during AAV capsid purification, ensuring purity.
