CD59 (NM_000611) Human Mass Spec Standard
$3,360.00
3 Weeks*
Specifications
| Product Data | |
| Tag | C-Myc/DDK |
|---|---|
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC218343 |
| Predicted MW | 14.2 kDa |
| Protein Sequence | |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
| Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_000602 |
| RefSeq Size | 7635 |
| RefSeq ORF | 384 |
| Synonyms | 1F5; 16.3A5; EJ16; EJ30; EL32; G344; HRF-20; HRF20; MAC-IP; MACIF; MEM43; MIC11; MIN1; MIN2; MIN3; MIRL; MSK21; p18-20 |
| Locus ID | 966 |
| UniProt ID | P13987 |
| Cytogenetics | 11p13 |
| Summary | This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. provided by RefSeq, Jul 2008 |
| Protein Families | Druggable Genome |
| Protein Pathways | Complement and coagulation cascades, Hematopoietic cell lineage |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "CD59" proteins (23)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| LC404397 | Lyophilized CD59 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC404398 | Lyophilized CD59 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC404399 | Lyophilized CD59 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC424608 | Lyophilized CD59 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC426723 | Lyophilized CD59 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC426724 | Lyophilized CD59 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC426725 | Lyophilized CD59 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC426726 | Lyophilized CD59 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC430908 | Lyophilized CD59 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC430909 | Lyophilized CD59 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC430910 | Lyophilized CD59 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY404397 | Transient overexpression lysate of CD59 molecule, complement regulatory protein (CD59), transcript variant 3 (as WB positive control) | 100 ug |
$436.00
|
|
| LY404398 | Transient overexpression lysate of CD59 molecule, complement regulatory protein (CD59), transcript variant 1 (as WB positive control) | 100 ug |
$436.00
|
|
| LY404399 | Transient overexpression lysate of CD59 molecule, complement regulatory protein (CD59), transcript variant 4 (as WB positive control) | 100 ug |
$436.00
|
|
| LY424608 | Transient overexpression lysate of CD59 molecule, complement regulatory protein (CD59), transcript variant 2 (as WB positive control) | 100 ug |
$436.00
|
|
| LY426723 | Transient overexpression lysate of CD59 molecule, complement regulatory protein (CD59), transcript variant 5 (as WB positive control) | 100 ug |
$436.00
|
|
| LY426724 | Transient overexpression lysate of CD59 molecule, complement regulatory protein (CD59), transcript variant 6 (as WB positive control) | 100 ug |
$436.00
|
|
| LY426725 | Transient overexpression lysate of CD59 molecule, complement regulatory protein (CD59), transcript variant 7 (as WB positive control) | 100 ug |
$436.00
|
|
| LY426726 | Transient overexpression lysate of CD59 molecule, complement regulatory protein (CD59), transcript variant 8 (as WB positive control) | 100 ug |
$436.00
|
|
| LY430908 | Transient overexpression lysate of CD59 molecule, complement regulatory protein (CD59), transcript variant 3 (as WB positive control) | 100 ug |
$436.00
|
|
| LY430909 | Transient overexpression lysate of CD59 molecule, complement regulatory protein (CD59), transcript variant 1 (as WB positive control) | 100 ug |
$436.00
|
|
| LY430910 | Transient overexpression lysate of CD59 molecule, complement regulatory protein (CD59), transcript variant 4 (as WB positive control) | 100 ug |
$436.00
|
|
| TP318343 | Recombinant protein of human CD59 molecule, complement regulatory protein (CD59), transcript variant 2, 20 µg | 20 ug |
$737.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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