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B Raf (BRAF) (NM_004333) Human Mass Spec Standard

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SKU
PH311013
BRAF MS Standard C13 and N15-labeled recombinant protein (NP_004324)
Size:
10 ug
  $3,360.00
3 Weeks*
Bulk/Customize

Frequently Bought Together (2)

TA500431 BRAF mouse monoclonal antibody, clone OTI5A9 (formerly 5A9) 100 ul
$447.00
LY401382 Transient overexpression lysate of v-raf murine sarcoma viral oncogene homolog B1 (BRAF) (as WB positive control) 100 ug
$436.00

Other products for "B Raf or NM_004333"

Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC211013
Predicted MW 84.4 kDa
Protein Sequence
Protein Sequence
>RC211013 protein sequence
Red=Cloning site Green=Tags(s)

MAALSGGGGGGAEPGQALFNGDMEPEAGAGAGAAASSAADPAIPEEVWNIKQMIKLTQEHIEALLDKFGG
EHNPPSIYLEAYEEYTSKLDALQQREQQLLESLGNGTDFSVSSSASMDTVTSSSSSSLSVLPSSLSVFQN
PTDVARSNPKSPQKPIVRVFLPNKQRTVVPARCGVTVRDSLKKALMMRGLIPECCAVYRIQDGEKKPIGW
DTDISWLTGEELHVEVLENVPLTTHNFVRKTFFTLAFCDFCRKLLFQGFRCQTCGYKFHQRCSTEVPLMC
VNYDQLDLLFVSKFFEHHPIPQEEASLAETALTSGSSPSAPASDSIGPQILTSPSPSKSIPIPQPFRPAD
EDHRNQFGQRDRSSSAPNVHINTIEPVNIDDLIRDQGFRGDGGSTTGLSATPPASLPGSLTNVKALQKSP
GPQRERKSSSSSEDRNRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVKMLNVTAP
TPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQT
AQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDK
NPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKK
RDERPLFPQILASIELLARSLPKIHRSASEPSLNRAGFQTEDFSLYACASPKTPIQAGGYGAFPVH

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_004324
RefSeq Size 2949
RefSeq ORF 2298
Synonyms B-raf; B-RAF1; BRAF1; NS7; RAFB1
Locus ID 673
UniProt ID P15056
Cytogenetics 7q34
Summary This gene encodes a protein belonging to the RAF family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERK signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene, most commonly the V600E mutation, are the most frequently identified cancer-causing mutations in melanoma, and have been identified in various other cancers as well, including non-Hodgkin lymphoma, colorectal cancer, thyroid carcinoma, non-small cell lung carcinoma, hairy cell leukemia and adenocarcinoma of lung. Mutations in this gene are also associated with cardiofaciocutaneous, Noonan, and Costello syndromes, which exhibit overlapping phenotypes. A pseudogene of this gene has been identified on the X chromosome. provided by RefSeq, Aug 2017
Protein Families Druggable Genome, Protein Kinase
Protein Pathways Acute myeloid leukemia, Bladder cancer, Chemokine signaling pathway, Chronic myeloid leukemia, Colorectal cancer, Endometrial cancer, ErbB signaling pathway, Focal adhesion, Glioma, Insulin signaling pathway, Long-term depression, Long-term potentiation, MAPK signaling pathway, Melanoma, mTOR signaling pathway, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Non-small cell lung cancer, Pancreatic cancer, Pathways in cancer, Progesterone-mediated oocyte maturation, Prostate cancer, Regulation of actin cytoskeleton, Renal cell carcinoma, Thyroid cancer, Vascular smooth muscle contraction
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Other "B Raf" proteins (13)
SKU Description Size Price
LC401382 Lyophilized BRAF HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY401382 Transient overexpression lysate of v-raf murine sarcoma viral oncogene homolog B1 (BRAF) (as WB positive control) 100 ug
$436.00
TP311013 Recombinant protein of human v-raf murine sarcoma viral oncogene homolog B1 (BRAF), 20 µg 20 ug
$867.00
TP700031 Recombinant protein of human v-raf murine sarcoma viral oncogene homolog B1 (BRAF) V600E mutant, expressed in human cells 20 ug
$900.00
TP700032 Recombinant protein of human v-raf murine sarcoma viral oncogene homolog B1 (BRAF) kinase domain, expressed in human cells 20 ug
$900.00
TP700033 Recombinant protein of human v-raf murine sarcoma viral oncogene homolog B1 (BRAF) kinase domain V600E mutant, expressed in human cells 20 ug
$900.00
TP700044 Recombinant protein of human v-raf murine sarcoma viral oncogene homolog B1 (BRAF) V600A mutant, expressed in human cells 20 ug
$900.00
TP700046 Recombinant protein of human v-raf murine sarcoma viral oncogene homolog B1 (BRAF) V600G mutant, expressed in human cells 20 ug
$900.00
TP700047 Recombinant protein of human v-raf murine sarcoma viral oncogene homolog B1 (BRAF) V600M mutant, expressed in human cells 20 ug
$900.00
TP700048 Recombinant protein of human v-raf murine sarcoma viral oncogene homolog B1 (BRAF) V600D mutant, expressed in human cells 20 ug
$900.00
TP700049 Recombinant protein of human v-raf murine sarcoma viral oncogene homolog B1 (BRAF) V600R mutant, expressed in human cells 20 ug
$900.00
TP700050 Recombinant protein of human v-raf murine sarcoma viral oncogene homolog B1 (BRAF) V600K mutant, expressed in human cells 20 ug
$900.00
TP700051 Recombinant protein of human v-raf murine sarcoma viral oncogene homolog B1 (BRAF) K601E mutant, expressed in human cells 20 ug
$900.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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