Human GXYLT1 activation kit by CRISPRa

SKU GA117031

GXYLT1 CRISPRa kit - CRISPR gene activation of human glucoside xylosyltransferase 1

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: GXYLT1
• Locus ID: 283464
• Components:

  GA117031G1, GXYLT1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA117031G2, GXYLT1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA117031G3, GXYLT1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001099650, NM_173601
• UniProt ID: Q4G148
• Synonyms: GLT8D3
• Summary: GXYLT1 is a xylosyltransferase (EC 2.4.2.-) that adds the first xylose to O-glucose-modified residues in the epidermal growth factor (EGF; MIM 131530) repeats of proteins such as NOTCH1 (MIM 190198) (Sethi et al., 2010 [PubMed 19940119]).[supplied by OMIM, Mar 2010]