Human C9orf21 (AAED1) activation kit by CRISPRa

SKU GA116259

PRXL2C CRISPRa kit - CRISPR gene activation of human peroxiredoxin like 2C

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: PRXL2C
• Locus ID: 195827
• Components:

  GA116259G1, C9orf21 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA116259G2, C9orf21 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA116259G3, C9orf21 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_153698
• UniProt ID: Q7RTV5
• Synonyms: C9orf21
• Summary: May regulate positively ERK1/2 signaling and AKT1 activation leading to HIF1A up-regulation with an increased expression of glycolysis genes and enhanced glycolysis.[UniProtKB/Swiss-Prot Function]