Human TXNL6 (NXNL1) activation kit by CRISPRa

SKU GA114551

NXNL1 CRISPRa kit - CRISPR gene activation of human nucleoredoxin like 1

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: NXNL1
• Locus ID: 115861
• Components:

  GA114551G1, TXNL6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA114551G2, TXNL6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA114551G3, TXNL6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_138454
• UniProt ID: Q96CM4
• Synonyms: RDCVF; TXNL6
• Summary: Retinitis pigmentosa (RP) is a disease that leads to blindness by degeneration of cone photoreceptors. Rods produce factors required for cone viability. The protein encoded by this gene is one of those factors and is similar to a truncated form of thioredoxin. This gene has been proposed to have therapeutic value against RP. [provided by RefSeq, Dec 2015]