Human G gamma12 (GNG12) activation kit by CRISPRa

SKU GA111077

GNG12 CRISPRa kit - CRISPR gene activation of human G protein subunit gamma 12

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: GNG12
• Locus ID: 55970
• Components:

  GA111077G1, G gamma12 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA111077G2, G gamma12 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA111077G3, G gamma12 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_018841
• UniProt ID: Q9UBI6
• Synonyms: FLJ31352; FLJ34695
• Summary: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.[UniProtKB/Swiss-Prot Function]