Human PKDREJ activation kit by CRISPRa

SKU GA107049

PKDREJ CRISPRa kit - CRISPR gene activation of human polycystin family receptor for egg jelly

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: PKDREJ
• Locus ID: 10343
• Components:

  GA107049G1, PKDREJ gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA107049G2, PKDREJ gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA107049G3, PKDREJ gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_006071
• UniProt ID: Q9NTG1
• Synonyms: OTTHUMP00000028714; polycystic kidney disease (polycystin) and REJ (sperm receptor for egg jelly, sea urchin homolog)-like; polycystic kidney disease (polycystin) and REJ (sperm receptor for egg jelly homolog, sea urchin)-like; receptor for egg jelly-like
• Summary: This intronless gene encodes a member of the polycystin protein family. The encoded protein contains 11 transmembrane domains, a receptor for egg jelly (REJ) domain, a G-protein-coupled receptor proteolytic site (GPS) domain, and a polycystin-1, lipoxygenase, alpha-toxin (PLAT) domain. This protein may play a role in human reproduction. Alternative splice variants have been described but their biological natures have not been determined. [provided by RefSeq, Jul 2008]