Human Visfatin (NAMPT) activation kit by CRISPRa

SKU GA106878

NAMPT CRISPRa kit - CRISPR gene activation of human nicotinamide phosphoribosyltransferase

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: NAMPT
• Locus ID: 10135
• Components:

  GA106878G1, Visfatin gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA106878G2, Visfatin gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA106878G3, Visfatin gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_005746, NM_182790
• UniProt ID: P43490
• Synonyms: 1110035O14Rik; PBEF; PBEF1; VF; VISFATIN
• Summary: This gene encodes a protein that catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein belongs to the nicotinic acid phosphoribosyltransferase (NAPRTase) family and is thought to be involved in many important biological processes, including metabolism, stress response and aging. This gene has a pseudogene on chromosome 10. [provided by RefSeq, Feb 2011]