Human Paxillin (PXN) activation kit by CRISPRa

SKU GA103964

PXN CRISPRa kit - CRISPR gene activation of human paxillin

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: PXN
• Locus ID: 5829
• Components:

  GA103964G1, Paxillin gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103964G2, Paxillin gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103964G3, Paxillin gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001080855, NM_001243756, NM_002859, NM_025157
• UniProt ID: P49023
• Synonyms: FLJ16691
• Summary: This gene encodes a cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. These isoforms exhibit different expression pattern, and have different biochemical, as well as physiological properties (PMID:9054445). [provided by RefSeq, Aug 2011]