Human PDE6 gamma (PDE6G) activation kit by CRISPRa

SKU GA103445

PDE6G CRISPRa kit - CRISPR gene activation of human phosphodiesterase 6G

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: PDE6G
• Locus ID: 5148
• Components:

  GA103445G1, PDE6 gamma gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103445G2, PDE6 gamma gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103445G3, PDE6 gamma gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_002602, NR_026872, NM_001365724, NM_001365725, NR_158591
• UniProt ID: P18545
• Synonyms: PDEG; RP57
• Summary: This gene encodes the gamma subunit of cyclic GMP-phosphodiesterase, which is composed of alpha- and beta- catalytic subunits and two identical, inhibitory gamma subunits. This gene is expressed in rod photoreceptors and functions in the phototransduction signaling cascade. It is also expressed in a variety of other tissues, and has been shown to regulate the c-Src protein kinase and G-protein-coupled receptor kinase 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2009]