DNAJB4 (NM_007034) Human Tagged ORF Clone Lentiviral Particle
SKU
RC203743L1V
Lenti ORF particles, DNAJB4 (Myc-DDK tagged) - Human DnaJ (Hsp40) homolog, subfamily B, member 4 (DNAJB4), 200ul, >10^7 TU/mL
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
---|---|
Tag | Myc-DDK |
Target Symbol | DNAJB4 |
Synonyms | DjB4; DNAJW; HLJ1 |
Vector | pLenti-C-Myc-DDK |
Mammalian Cell Selection | None |
Sequence Data |
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC203743).
|
ACCN | NM_007034 |
ORF Size | 1011 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Shipping | Dry Ice |
Reference Data | |
RefSeq | NM_007034.3 |
RefSeq Size | 2250 bp |
RefSeq ORF | 1014 bp |
Locus ID | 11080 |
UniProt ID | Q9UDY4 |
Cytogenetics | 1p31.1 |
Domains | DnaJ, DnaJ_C |
MW | 37.8 kDa |
Summary | The protein encoded by this gene is a molecular chaperone, tumor suppressor, and member of the heat shock protein-40 family. The encoded protein binds the cell adhesion protein E-cadherin and targets it to the plasma membrane. This protein also binds incorrectly folded E-cadherin and targets it for endoplasmic reticulum-associated degradation. This gene is a strong tumor suppressor for colorectal carcinoma, and downregulation of it may serve as a good biomarker for predicting patient outcomes. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015] |
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