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Lenti Citations
OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.
Search citations by gene symbols or target names
Here are some of the recent papers making use of OriGene products by fellow researchers.
| Target | Research Paper | Journal | Product | SKU |
|---|---|---|---|---|
| A1CF | The RNA-Binding Protein A1CF Regulates Hepatic Fructose and Glycerol Metabolism via Alternative RNA Splicing | Cell Rep 2019 | Lenti | MR224176L1 |
| A230097K15RIK | Glycerol-3-phosphate is a FGF23 regulator derived from the injured kidney | J. Clin. Invest. 2020 | Lenti | TL506938V |
| A530057A03RIK | Glycerol-3-phosphate is a FGF23 regulator derived from the injured kidney | J. Clin. Invest. 2020 | Lenti | TL517838V |
| ABAT | Dnmt3b ablation impairs fracture repair through upregulation of Notch pathway | JCI Insight 2020 | Lenti | TL508059V |
| ABCA1 | ABCA1/ABCB1 Ratio Determines Chemo- and Immune-Sensitivity in Human Osteosarcoma | Cells 2020 | Lenti | TL315036V |
| ABCA1 | Monitoring the itinerary of lysosomal cholesterol in Niemann-Pick Type C1-deficient cells after cyclodextrin treatment | J. Lipid Res. 2020 | Lenti | TL315036 |
| ABCC5 | Human drug efflux transporter ABCC5 confers acquired resistance to pemetrexed in breast cancer | Cancer cell international 2021 | Lenti | TL315024 |
| ABCG1 | Monitoring the itinerary of lysosomal cholesterol in Niemann-Pick Type C1-deficient cells after cyclodextrin treatment | J. Lipid Res. 2020 | Lenti | TL306915 |
| ACE2 | Cross-sectional evaluation of humoral responses against SARS-CoV-2 Spike | bioRxiv : the preprint server for biology 2020 | Lenti | RC208442L4 |
| ACKR3 | Modulation of CXC-motif chemokine receptor 7, but not 4, expression is related to migration of the human prostate cancer cell LNCaP: regulation by androgen and inflammatory stimuli | Inflamm. Res. 2019 | Lenti | TL515747 |
| ACSL1 | Acyl-CoA synthetase 1 deficiency alters cardiolipin species and impairs mitochondrial function | J. Lipid Res. Aug 2015 | Lenti | TL709438 |
| ACSL4 | The positive feedback between ACSL4 expression and O-GlcNAcylation contributes to the growth and survival of hepatocellular carcinoma | Aging (Albany NY) 2020 | Lenti | RC221413L4 |
| ACTR3 | Arp2/3 nucleates F-actin coating of fusing insulin granules in pancreatic β cells to control insulin secretion | J. Cell. Sci. 2020 | Lenti | MR217895L2 |
| ADAM12 | A Disintegrin and Metalloprotease 12 Promotes Tumor Progression by Inhibiting Apoptosis in Human Colorectal Cancer | Cancers 2021 | Lenti | TL306850 |
| ADAM9 | Analysis of ADAM9 Regulation and Function in Vestibular Schwannoma Primary Cells | Research Square 2020 | Lenti | TL314947V |
| ADAMTS8 | Differential expression of secreted factors SOSTDC1 and ADAMTS8 cause pro-fibrotic changes in linear morphoea fibroblasts | Br. J. Dermatol. 2018 | Lenti | RC212446L4V |
| ADAR | Adenosine-to-inosine RNA editing controls cathepsin S expression in atherosclerosis by enabling HuR-mediated post-transcriptional regulation | Nat. Med. 2016 | Lenti | RC207522L1 |
| ADGRG1 | GPR56/ADGRG1 is associated with response to antidepressant treatment | Nat Commun 2020 | Lenti | MR210044L2V |
| ADH1A | Further evidence supporting a potential role for ADH1B in obesity | Scientific reports 2021 | Lenti | RC205391L3 |
| AEG-1 | AEG-1 promotes mesenchymal transition through the activation of Rho GTPases in human glioblastoma cells | Oncol. Rep. 2016 | Lenti | RC207238L1 |
| AGBL2 | AGBL2 promotes cancer cell growth through IRGM-regulated autophagy and enhanced Aurora A activity in hepatocellular carcinoma | Cancer Lett.2017 | Lenti | TL306802 |
| AGER | Effect of AGER on the biological behavior of non‑small cell lung cancer H1299 cells | Mol Med Rep 2020 | Lenti | RC204664L2 |
| AGER | AGER promotes proliferation and migration in cervical cancer | Biosci. Rep. 2018 | Lenti | RC204664L2 |
| AGO2 | AGO2 mediates MYC mRNA stability in hepatocellular carcinoma | Mol. Cancer Res. 2020 | Lenti | TL313261 |
| AGO2 | AGO2 mediates MYC mRNA stability in hepatocellular carcinoma | Mol. Cancer Res. 2020 | Lenti | RC218078L2 |
| AGPAT2 | Terapia génica y celular para la corrección de la Lipodistrofia Congénita Generalizada | Thesis Jul 2014 | Lenti | TL314894 |
| AHR | Sustained activation of the Aryl hydrocarbon Receptor transcription factor promotes resistance to BRAF-inhibitors in melanoma | Nat Commun 2018 | Lenti | TL320259 |
| AHR | Blockade of IDO-kynurenine-AhR metabolic circuitry abrogates IFN-γ-induced immunologic dormancy of tumor-repopulating cells | Nat Commun 2017 | Lenti | TL320259 |
| AIF1 | AIF-regulated oxidative phosphorylation supports lung cancer development | Cell Res. 2019 | Lenti | TL314878 |
| AIFM1 | Overexpression of apoptosis-inducing factor mitochondrion-associated 1 (AIFM1) induces apoptosis by promoting the transcription of caspase3 and DRAM in hepatoma cells | Biochem. Biophys. Res. Commun. 2018 | Lenti | TL302572 |
| AIRE | The Role of AIRE in the Immunity Against Candida Albicans in a Model of Human Macrophages | Front. Immunol. 2018 | Lenti | RC213497L2 |
| AKT1 | MAT1 facilitates the lung metastasis of osteosarcoma through upregulation of AKT1 expression | Life Sci. 2019 | Lenti | TL320260 |
| AKT3 | Restoring miR122 in human stem-like hepatocarcinoma cells, prompts tumor dormancy through Smad-independent TGF-β pathway | Oncotarget 2016 | Lenti | TL320629 |
| ALDH18A1 | Global metabolic profiling identifies a pivotal role of proline and hydroxyproline metabolism in supporting hypoxic response in hepatocellular carcinoma | Clin. Cancer Res.2017 | Lenti | TL314847 |
| ALDH1A1 | Stemness marker ALDH1A1 promotes tumor angiogenesis via retinoic acid/HIF-1α/VEGF signalling in MCF-7 breast cancer cells | J. Exp. Clin. Cancer Res. 2018 | Lenti | RC200723L1V |
| ALDH3A1 | ALDH3A1 Overexpression in Melanoma and Lung Tumors Drives Cancer Stem Cell Expansion, Impairing Immune Surveillance through Enhanced PD-L1 Output | Cancers (Basel) 2019 | Lenti | RC202440L1 |
| ALDH3A1 | Mutation of the gene encoding the circadian clock component PERIOD2 in oncogenic cells confers chemoresistance by up-regulating the Aldh3a1 gene | J. Biol. Chem. 2018 | Lenti | TL510377 |
| ALDH3A1 | Optimized dosing schedule based on circadian dynamics of mouse breast cancer stem cells improves the anti-tumor effects of aldehyde dehydrogenase | Cancer Res. 2018 | Lenti | TL510377 |
| ALKBH1 | The stress specific impact of ALKBH1 on tRNA cleavage and tiRNA generation | bioRxiv 2020 | Lenti | RR214755L2V |
| ALOX15 | PDn-3 DPA Pathway Regulates Human Monocyte Differentiation and Macrophage Function | Cell Chem Biol 2018 | Lenti | TL314822 |
| AMD | Increased polyamines as protective disease modifiers in Congenital Muscular Dystrophy | Hum. Mol. Genet. 2018 | Lenti | RR205647L2 |
| AMELX | Effects of full-length human amelogenin on the differentiation of dental epithelial cells and osteoblastic cells | Arch. Oral Biol. 2019 | Lenti | RC215582L1 |
| AMFR | Aberrant corticosteroid metabolism in tumor cells enables GR takeover in enzalutamide resistant prostate cancer | Elife 2017 | Lenti | TL316441 |
| ANGPTL4 | Interaction of tumor cells and astrocytes promotes breast cancer brain metastases through TGF-β2/ANGPTL4 axes | NPJ Precis Oncol 2019 | Lenti | TL317168 |
| ANO1 | Suppression of CaMKIIβ Inhibits ANO1-Mediated Glioblastoma Progression | Cells 2020 | Lenti | TL300993 |
| ANXA2 | Clinical Significance of Annexin A2 Expression in Breast Cancer Patients | Cancers 2020 | Lenti | RC205081L4 |
| ANXA2 | Intracellular targeting of annexin A2 inhibits tumor cell adhesion, migration, and in vivo grafting | Sci Rep 2017 | Lenti | TL314772 |
| AP2S1 | Murine leukemia virus glycosylated Gag reduces murine SERINC5 protein expression at steady-state levels via endosome/lysosome pathway to counteract the SERINC5 antiretroviral activity | J. Virol. 2018 | Lenti | TL306655 |
| AP2S1 | HIV-1 Nef antagonizes SERINC5 restriction by downregulation of SERINC5 via the endosome/lysosome system | J. Virol. 2018 | Lenti | TL306655 |
| APOE | C/EBPβ is a key transcription factor for APOE and preferentially mediates ApoE4 expression in Alzheimer\'s disease | Molecular psychiatry 2020 | Lenti | TL314721 |
| AQP4 | Targeting Aquaporin-4 Subcellular Localization to Treat Central Nervous System Edema | Cell 2020 | Lenti | TL709442 |
| AQP4 | Analysis of chromatin accessibility uncovers TEAD1 as a regulator of migration in human glioblastoma | Nat Commun 2018 | Lenti | RC204693L1 |
| ARHGEF7 | ARHGEF7 promotes metastasis of colorectal adenocarcinoma by regulating the motility of cancer cells | Int. J. Oncol. 2018 | Lenti | TL306604 |
| ARHGEF7 | ARHGEF7 promotes metastasis of colorectal adenocarcinoma by regulating the motility of cancer cells | Int. J. Oncol. 2018 | Lenti | RC218946L1 |
| ARID3B | ARID3B Directly Regulates Ovarian Cancer Promoting Genes | PLoS ONE Jun 2015 | Lenti | RC206328L2 |
| ATF4 | A Novel Dual Kinase Function of the RET Proto-oncogene Negatively Regulates Activating Transcription Factor 4-Mediated Apoptosis | J. Biol. Chem. Mar 2015 | Lenti | RC222709L1 |
| ATG5 | Autophagy regulates trophoblast invasion by targeting NF-κB activity | Sci Rep 2020 | Lenti | TL314610 |
| ATG5 | Basal autophagy is pivotal for Hodgkin and Reed-Sternberg cells' survival and growth revealing a new strategy for Hodgkin lymphoma treatment | Oncotarget 2016 | Lenti | TL500113 |
| ATG7 | Altered mitochondrial quality control in Atg7-deficient VSMCs promotes enhanced apoptosis and is linked to unstable atherosclerotic plaque phenotype | Cell Death Dis 2019 | Lenti | TL504956V |
| ATM | SIRT3, a metabolic target linked to ataxia-telangiectasia mutated (ATM) gene deficiency in diffuse large B-cell lymphoma | Scientific reports 2020 | Lenti | TL320267V |
| ATM | ATM and ATR play complementary roles in the behavior of excitatory and inhibitory vesicle populations | Proc. Natl. Acad. Sci. U.S.A. 2017 | Lenti | TL320267 |
| ATP1A1 | ATP1A1 Integrates AKT and ERK Signaling via Potential Interaction With Src to Promote Growth and Survival in Glioma Stem Cells | Front Oncol 2019 | Lenti | TL314602 |
| ATP1B2 | An Immunoaffinity-Based Method for Isolating Ultrapure Adult Astrocytes Based on ATP1B2 Targetting by the ACSA-2 Antibody | J. Biol. Chem. 2017 | Lenti | TL500159 |
| Atp7a | Knockdown of copper-transporting ATPase 1 (Atp7a) impairs iron flux in fully-differentiated rat (IEC-6) and human (Caco-2) intestinal epithelial cells | Metallomics 2016 | Lenti | TL711714 |
| Atr | ATM and ATR play complementary roles in the behavior of excitatory and inhibitory vesicle populations | Proc. Natl. Acad. Sci. U.S.A. 2017 | Lenti | TL519184 |
| AURKA | Aurora-A kinase oncogenic signaling mediates TGF-β-induced triple-negative breast cancer plasticity and chemoresistance | Oncogene 2021 | Lenti | TL320538 |
| AVPR2 | Sensory primary cilium is a responsive cAMP microdomain in renal epithelia | Sci Rep 2019 | Lenti | TL513450 |
| AXL | Modelling ponatinib resistance in tyrosine kinase inhibitor-naïve and dasatinib resistant BCR-ABL1+ cell lines | Oncotarget 2018 | Lenti | TL320269 |
| AXL | Implication of the Receptor Tyrosine Kinase AXL in Head and Neck Cancer Progression | Int J Mol Sci 2016 | Lenti | RC206431L2 |
| B2M | Interferon-γ signaling in human iPSC-derived neurons recapitulates neurodevelopmental disorder phenotypes | Sci Adv 2020 | Lenti | TL314543V |
| B2M | Mapping effector genes at lupus GWAS loci using promoter Capture-C in follicular helper T cells | Nat Commun 2020 | Lenti | TL314543 |
| B2M | Human follicular helper T cell promoter connectomes reveal novel genes and regulatory elements at SLE GWAS loci | bioRxiv 2019 | Lenti | TL314543 |
| B2M | Antiviral signalling in human IPSC-derived neurons recapitulates neurodevelopmental disorder phenotypes | BioRxiv 2019 | Lenti | TL314543V |
| BAP1 | Sensitivity of mesothelioma cells to PARP inhibitors is not dependent on BAP1 but is enhanced by temozolomide in cells with high-Schlafen 11and low-MGMT expression | J Thorac Oncol 2020 | Lenti | RC200378L4 |
| BCL2 | Nuclear factor erythroid 2-related factor 2 enhances carcinogenesis by suppressing apoptosis and promoting autophagy in nickel-transformed cells | J. Biol. Chem 2017 | Lenti | TL316461 |
| BCL2 | Inhibition of Bcl-2 potentiates AZD-2014-induced anti-head and neck squamous cell carcinoma cell activity | Biochem. Biophys. Res. Commun. Jun 2016 | Lenti | TL316461 |
| BCLN1 | Autophagy Induction Results in Enhanced Anoikis-resistance in Models of Peritoneal Disease | Mol. Cancer Res. 2016 | Lenti | TL314484 |
| BHLHE40 | BHLHE40, a third transcription factor required for insulin induction of SREBP-1c mRNA in rodent liver | Elife 2018 | Lenti | RR206868LV |
| BIRC5 | HAb18G/CD147 Promotes pSTAT3-Mediated Pancreatic Cancer Development via CD44s | Clin Cancer Res. 2013 Nov 22 | Lenti | TL315477 |
| BMI1 | Lens regeneration using endogenous stem cells with gain of visual function | Nature Mar 2016 | Lenti | TL314462 |
| BNIP3 | Phosphorylation dependent mitochondrial translocation of Nr4a3 provokes cardiomyocyte death | Research Square 2021 | Lenti | TL711845V |
| Brd4 | Inhibition of BRD4 Attenuates Cardiomyocyte Apoptosis via NF-κB pathway in a Rat Model of Myocardial Infarction | Cardiovasc Ther 2018 | Lenti | TL704216 |
| C13ORF34 | Bora downregulation results in radioresistance by promoting repair of double strand breaks | PLoS ONE Mar 2015 | Lenti | TL307294 |
| C1ORF115 | Systematic functional identification of cancer multi-drug resistance genes | Genome Biol. 2020 | Lenti | RC206246L2 |
| CAB39L | CAB39L elicited an anti-Warburg effect via a LKB1-AMPK-PGC1α axis to inhibit gastric tumorigenesis | Oncogene 2018 | Lenti | TL314249 |
| CACNA1B | Reduced N-Type Ca2+Channels in Atrioventricular Ganglion Neurons Are Involved in Ventricular Arrhythmogenesis | J Am Heart Assoc 2018 | Lenti | TL713159 |
| CACNA1C | Primary cilium regulates CaV1.2 expression through Wnt signaling | J. Cell. Physiol. April 2014 | Lenti | TL500242 |
| CACNA1G | Tumour-specific amplitude-modulated radiofrequency electromagnetic fields induce differentiation of hepatocellular carcinoma via targeting Cav3.2 T-type voltage-gated calcium channels and Ca2+ influx | EBioMedicine 2019 | Lenti | TL305680 |
| CACNA1G | Ca2+ and CACNA1H mediate targeted suppression of breast cancer brain metastasis by AM RF EMF | EBioMedicine 2019 | Lenti | TL305680 |
| CACNA1H | Tumour-specific amplitude-modulated radiofrequency electromagnetic fields induce differentiation of hepatocellular carcinoma via targeting Cav3.2 T-type voltage-gated calcium channels and Ca2+ influx | EBioMedicine 2019 | Lenti | TL314243 |
| CACNA1H | Ca2+ and CACNA1H mediate targeted suppression of breast cancer brain metastasis by AM RF EMF | EBioMedicine 2019 | Lenti | TL314243 |
| CACNA1I | Tumour-specific amplitude-modulated radiofrequency electromagnetic fields induce differentiation of hepatocellular carcinoma via targeting Cav3.2 T-type voltage-gated calcium channels and Ca2+ influx | EBioMedicine 2019 | Lenti | TL314242 |
| CACNA1I | Ca2+ and CACNA1H mediate targeted suppression of breast cancer brain metastasis by AM RF EMF | EBioMedicine 2019 | Lenti | TL314242 |
| CACNA2D1 | α2δ1 may be a potential marker for cancer stem cell in laryngeal squamous cell carcinoma | Cancer Biomark 2019 | Lenti | TL314240 |
| CACNA2D3 | Auxiliary α2δ1 and α2δ3 Subunits of Calcium Channels Drive Excitatory and Inhibitory Neuronal Network Development | J. Neurosci. 2020 | Lenti | TL713428 |
| CACNG4 | Amplification of a calcium channel subunit CACNG4 increases breast cancer metastasis | EBioMedicine 2020 | Lenti | RC205154L3 |
| CACNG4 | The calcium channel subunit gamma-4 is regulated by MafA and necessary for pancreatic beta-cell specification | Commun Biol 2019 | Lenti | RC205154L2 |
| CADM1 | MicroRNA-155-3p promotes breast cancer progression through down-regulating CADM1 | Onco Targets Ther 2019 | Lenti | TL312210 |
| CADM1 | Human T-Cell Leukemia Virus Type 1 (HTLV-1) Tax Requires CADM1/TSLC1 for Inactivation of the NF-?B Inhibitor A20 and Constitutive NF-?B Signaling | PLoS Pathog. Mar 2015 | Lenti | TL312210 |
| CAMKK2 | Neuronal Inactivity Co-opts LTP Machinery to Drive Potassium Channel Splicing and Homeostatic Spike Widening | Cell 2020 | Lenti | TL711303 |
| CAPN10 | Clinical significance of sHER2‑ECD and calpain‑10 expression in tumor tissues of patients with breast cancer | Oncol Rep 2020 | Lenti | TL305662 |
| CAR3 | Expression of Carbonic Anhydrase III, a Nucleus Pulposus Phenotypic Marker, is Hypoxia-responsive and Confers Protection from Oxidative Stress-induced Cell Death | Sci Rep 2018 | Lenti | TL710299 |
| CASP3 | Overexpression of apoptosis-inducing factor mitochondrion-associated 1 (AIFM1) induces apoptosis by promoting the transcription of caspase3 and DRAM in hepatoma cells | Biochem. Biophys. Res. Commun. 2018 | Lenti | TL305638 |
| CASR | Effects of pharmacological calcimimetics on colorectal cancer cells over-expressing the human calcium-sensing receptor | bioRxiv 2020 | Lenti | RC211229L4V |
| CASR | Hypoxia-Induced Mitogenic Factor Acts as a Nonclassical Ligand of Calcium-Sensing Receptor, Therapeutically Exploitable for Intermittent Hypoxia-Induced Pulmonary Hypertension | Hypertension 2017 | Lenti | TL709816 |
| CASR | Monocrotaline Induces Endothelial Injury and Pulmonary Hypertension by Targeting the Extracellular Calcium-Sensing Receptor | J Am Heart Assoc 2017 | Lenti | TL709816 |
| CBARA1 | miR-181c Activates Mitochondrial Calcium Uptake by Regulating MICU1 in the Heart | J Am Heart Assoc 2019 | Lenti | TL512307 |
| CBX8 | Upregulated CBX8 promotes cancer metastasis via the WNK2/MMP2 pathway | Molecular Therapy - Oncolytics 2020 | Lenti | RC203417L1 |
| CCDC85B | CCDC85B promotes non-small cell lung cancer cell proliferation and invasion | Mol. Carcinog. 2018 | Lenti | RC201086L1 |
| CCL2 | Improved insulin sensitivity in obese-diabetic mice viachitosan Nanomicelles mediated silencing of pro-inflammatory Adipocytokines | Nanomedicine : nanotechnology, biology, and medicine 2021 | Lenti | TL501987 |
| CCL2 | MCP-1 is overexpressed in triple-negative breast cancers and drives cancer invasiveness and metastasis | Breast Cancer Res. Treat. 2018 | Lenti | TL316716 |
| CCL2 | Chemokine Signaling Facilitates Early-stage Breast Cancer Survival and Invasion through Fibroblast-dependent Mechanisms | Mol. Cancer Res.2017 | Lenti | TL316716 |
| CCL2 | Regulatory T cells ameliorate tissue plasminogen activator-induced brain haemorrhage after stroke | Brain 2017 | Lenti | TL501987 |
| CCR2 | Chemokine Signaling Facilitates Early-stage Breast Cancer Survival and Invasion through Fibroblast-dependent Mechanisms | Mol. Cancer Res.2017 | Lenti | TL321181 |
| CD180 | A multi-omic analysis reveals the regulatory role of CD180 during the response of macrophages to Borrelia burgdorferi | Emerg Microbes Infect 2018 | Lenti | TL314107 |
| CD274 | Leukemic Extracellular Vesicles Induce Chimeric Antigen Receptor T Cell Dysfunction in Chronic Lymphocytic Leukemia | Molecular Therapy 2021 | Lenti | RC213071L4 |
| CD274 | Proteolytic processing of PD-L1 by ADAM proteases in breast cancer cells | Cancer Immunol. Immunother. 2019 | Lenti | RC213071L2V |
| CD274 | Salmonella Typhimurium increases functional PD-L1 synergistically with IFNγ in intestinal epithelial cells viaSalmonellaPathogenicity Island-2 | Infect. Immun. 2018 | Lenti | TL314098 |
| Cd274 | Host expression of PD-L1 determines efficacy of PD-L1 pathway blockade-mediated tumor regression | J. Clin. Invest. 2018 | Lenti | MR203953L2 |
| CD274 | PD-L1 up-regulation in melanoma increases disease aggressiveness and is mediated through miR-17-5p | Oncotarget 2017 | Lenti | TL314098V |
| CD28 | CTLA4-Ig prolongs graft survival specifically in young but not old mice | Am. J. Transplant. 2020 | Lenti | MR202454L4V |
| CD40 | A PPARγ-dependent miR-424/503-CD40 axis regulates inflammation mediated angiogenesis | Sci Rep 2017 | Lenti | RC201977L1 |
| CD44 | Gold-nanofève surface-enhanced Raman spectroscopy visualizes hypotaurine as a robust anti-oxidant consumed in cancer survival | Nat Commun 2018 | Lenti | TL314080 |
| CD47 | Targeting cluster of differentiation 47 improves the efficacy of anti-cytotoxic T-lymphocyte associated protein 4 treatment via antigen presentation enhancement in pancreatic ductal adenocarcinoma | Exp Ther Med 2020 | Lenti | MR204706L1 |
| CD47 | Targeting cluster of differentiation 47 improves the efficacy of anti-cytotoxic T-lymphocyte associated protein 4 treatment via antigen presentation enhancement in pancreatic ductal adenocarcinoma | Exp Ther Med 2020 | Lenti | TL501123 |
| CD70 | Breast cancer stem cells characterized by CD70 expression preferentially metastasize to the lungs | Breast Cancer 2018 | Lenti | TL308721 |
| CDC2 | Adenylyl cyclase activating polypeptide reduces phosphorylation and toxicity of the polyglutamine-expanded androgen receptor in spinobulbar muscular atrophy | Sci Transl Med 2016 | Lenti | TL320288 |
| CDC42 | shRNA mediated inhibition of Cdc42 gene expression in Calu-6 lung cancer cells | bioRxiv 2017 | Lenti | TL305497 |
| CDC7 | CDC7-dependent transcriptional regulation of RAD54L is essential for tumorigenicity and radio-resistance of glioblastoma | Transl Oncol 2018 | Lenti | TL320578 |
| CDH11 | Analysis of chromatin accessibility uncovers TEAD1 as a regulator of migration in human glioblastoma | Nat Commun 2018 | Lenti | RC203810L1 |
| CDH11 | Cadherin-11 involves in synovitis and increases the migratory and invasive capacity of fibroblast-like synoviocytes of osteoarthritis | Int. Immunopharmacol. Mar 2015 | Lenti | RC203810L2 |
| CDH3 | DSCAM promotes self-avoidance in the developing mouse retina by masking the functions of cadherin superfamily members | Proc. Natl. Acad. Sci. U.S.A. 2018 | Lenti | MR227582L1 |
| CDK2 | Cyclin-Dependent Kinase 2 Promotes Tumor Proliferation and Induces Radio Resistance in Glioblastoma | Transl Oncol 2016 | Lenti | TL320291 |
| CDKN1A | TERT and DNMT1 expression predict sensitivity to decitabine in gliomas | Neuro-oncology 2020 | Lenti | TL305469 |
| CDKN1A | Adenylyl cyclase activating polypeptide reduces phosphorylation and toxicity of the polyglutamine-expanded androgen receptor in spinobulbar muscular atrophy | Sci Transl Med 2016 | Lenti | TL305469 |
| CDKN1B | Chronic p27Kip1 Induction by Dexamethasone Causes Senescence Phenotype and Permanent Cell Cycle Blockade in Lung Adenocarcinoma Cells Over-expressing Glucocorticoid Receptor | Sci Rep 2018 | Lenti | RC201661L1 |
| CDKN2A | p16(INK4A) induces senescence and inhibits EMT through microRNA-141/microRNA-146b-5p-dependent repression of AUF1 | Mol. Carcinog. 2016 | Lenti | RC220937L2 |
| CDKN2A | TALE-mediated epigenetic suppression of CDKN2A increases replication in human fibroblasts | J. Clin. Invest. May 2015 | Lenti | RC220937L1 |
| CDKN2A | The Cytokine IL-6 Reactivates Breast Stromal Fibroblasts through Transcription Factor STAT3-dependent Up-regulation of the RNA Binding Protein AUF1 | J. Biol. Chem. Sep 2014 | Lenti | RC220937L1 |
| CEACAM6 | Biological Functions and Identification of Novel Biomarker Expressed on the Surface of Breast Cancer-Derived Cancer Stem Cells via Proteomic Analysis | Mol. Cells 2020 | Lenti | TL314003 |
| CEBPA | C/EBPβ is a key transcription factor for APOE and preferentially mediates ApoE4 expression in Alzheimer\'s disease | Molecular psychiatry 2020 | Lenti | TL316491 |
| CEBPA | C/EBPβ regulates delta-secretase expression and mediates pathogenesis in mouse models of Alzheimer's disease | Nat Commun 2018 | Lenti | TL316491 |
| CEBPB | C/EBPβ is a key transcription factor for APOE and preferentially mediates ApoE4 expression in Alzheimer\'s disease | Molecular psychiatry 2020 | Lenti | TL320301 |
| CEBPB | C/EBPβ regulates delta-secretase expression and mediates pathogenesis in mouse models of Alzheimer's disease | Nat Commun 2018 | Lenti | TL320301 |
| CES1 | Impaired cholesterol efflux in retinal pigment epithelium of individuals with juvenile macular degeneration | American journal of human genetics 2021 | Lenti | TL313972V |
| CGAS | The cytosolic DNA sensor cGAS recognizes neutrophil extracellular traps | Science signaling 2021 | Lenti | RC212386L4 |
| CGGBP1 | CGGBP1 regulates CTCF occupancy at repeats | Epigenetics Chromatin 2019 | Lenti | TL313955 |
| CGGBP1 | CGGBP1 regulates chromatin barrier activity and CTCF occupancy at repeats | bioRxiv 2019 | Lenti | TL313955 |
| CGGBP1 | CGGBP1 regulates chromatin barrier activity and CTCF occupancy at repeats | bioRxiv 2019 | Lenti | RC208653L1 |
| CHCHD2 | FTO Plays an Oncogenic Role in Acute Myeloid Leukemia as a N(6)-Methyladenosine RNA Demethylase | Cancer Cell 2016 | Lenti | TL317169 |
| CHCHD4 | Light-Driven Regeneration of Cone Visual Pigments through a Mechanism Involving RGR Opsin in Müller Glial Cells | Neuron 2019 | Lenti | TL305417 |
| CHD5 | miRNA-24-3p promotes cell proliferation and regulates chemosensitivity in head and neck squamous cell carcinoma by targeting CHD5 | Future Oncol 2016 | Lenti | RC221815L1 |
| CHEK1 | Ubiquitination of the DNA-damage checkpoint kinase CHK1 by TRAF4 is required for CHK1 activation | J Hematol Oncol 2020 | Lenti | RC225807L4 |
| CHEK2 | CHEK2 represses breast stromal fibroblasts and their paracrine tumor-promoting effects through suppressing SDF-1 and IL-6 | BMC Cancer 2016 | Lenti | RC212127L1 |
| CIC | Inactivation of Capicua drives cancer metastasis | Nat. Genet. 2016 | Lenti | RC215209L2 |
| CLDN18 | Claudin-18-mediated YAP activity regulates lung stem and progenitor cell homeostasis and tumorigenesis | J. Clin. Invest. 2018 | Lenti | RC212135L2 |
| CLDN4 | Ovarian Tumor Cell Expression of Claudin-4 Reduces Apoptotic Response to Paclitaxel | Mol. Cancer Res. 2019 | Lenti | RC200490L2 |
| CLTC | Dynamin and endocytosis are required for the fusion of osteoclasts and myoblasts | J. Cell Biol. Oct 2014 | Lenti | TL516542 |
| CLTRN | CLTRN, regulated by NRF1/RAN/DLD protein complex, enhances radiation sensitivity of hepatocellular carcinoma cells through ferroptosis pathway | International journal of radiation oncology, biology, physics 2021 | Lenti | RC204775L2 |
| Control Particle | The small G-protein RalA promotes progression and metastasis of triple-negative breast cancer | Breast cancer research : BCR 2021 | Lenti | TR30021V |
| Control Particle | A Potent and Selective Small-Molecule Degrader of STAT3 Achieves Complete Tumor Regression In Vivo | Cancer Cell 2019 | Lenti | PS100092V |
| Control Particles | Activation of the eIF2α/ATF4 axis drives triple-negative breast cancer radioresistance by promoting glutathione biosynthesis | Redox Biology 2021 | Lenti | PS100092V |
| Control Particles | Analysis of HOX gene expression and the effects of HOXA9 overexpression in fibroblasts derived from keloid lesions and normal skin | Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2021 | Lenti | PS100071V |
| Control Particles | Epigenetic reprogramming of tumor cell-intrinsic STING function sculpts antigenicity and T cell recognition of melanoma | Proceedings of the National Academy of Sciences of the United States of America 2021 | Lenti | TR30021V |
| Control Particles | The Small G-Protein RalA Promotes Progression and Metastasis of Triple Negative Breast Cancer | Research Square 2021 | Lenti | TR30021V |
| Control Particles | Using zebrafish to elucidate glial-vascular interactions during CNS development | bioRxiv 2021 | Lenti | PS100093V |
| Control Particles | CLTRN, regulated by NRF1/RAN/DLD protein complex, enhances radiation sensitivity of hepatocellular carcinoma cells through ferroptosis pathway | International journal of radiation oncology, biology, physics 2021 | Lenti | PS100071V |
| Control Particles | Cathelicidin Suppresses Colon Cancer Metastasis via a P2RX7-Dependent Mechanism | Molecular Therapy - Oncolytics 2019 | Lenti | PS100064V |
| CORO1B | Coronin 1B serine 2 phosphorylation by p38a is critical for vascular endothelial growth factor-induced migration of human umbilical vein endothelial cells | Cell. Signal. 2016 | Lenti | RC203023L2 |
| Cpne7 | Dentin sialophosphoprotein expression in enamel is regulated by Copine-7, a preameloblast-derived factor | Arch. Oral Biol. 2017 | Lenti | TL513948 |
| CPSF1 | Aberrant expression of CPSF1 promotes head and neck squamous cell carcinoma via regulating alternative splicing | PLoS ONE 2020 | Lenti | RC203519L4 |
| CRADD | RAIDD Mediates TLR3 and IRF7 Driven Type I Interferon Production | Cell. Physiol. Biochem. 2016 | Lenti | TL319843 |
| Creb3l1 | CREB3L1-mediated functional and structural adaptation of the secretory pathway in hormone-stimulated thyroid cells | J. Cell. Sci.2017 | Lenti | TL700673 |
| CREBBP | Histone Acetyltransferase p300 Induces De Novo Super-Enhancers to Drive Cellular Senescence | Mol. Cell 2019 | Lenti | RC219036L1 |
| CRHR1 | Frontline Science: Corticotropin-releasing factor receptor subtype 1 is a critical modulator of mast cell degranulation and stress-induced pathophysiology | J. Leukoc. Biol. 2017 | Lenti | RC226816L2 |
| CSPG5 | Chondroitin sulfate proteoglycan-5 forms perisynaptic matrix assemblies in the adult rat cortex | Cell. Signal. 2020 | Lenti | RR200364L2 |
| CT45A1 | Multi-level Proteomics Identifies CT45 as a Chemosensitivity Mediator and Immunotherapy Target in Ovarian Cancer | Cell 2018 | Lenti | TL315298 |
| CTNNB1 | MDMX acts as a pervasive preleukemic-to-acute myeloid leukemia transition mechanism | Cancer cell 2021 | Lenti | TL500280 |
| CTNNB1 | Overexpression of G3BP1 facilitates the progression of colon cancer by activating β‑catenin signaling | Molecular medicine reports 2020 | Lenti | TL313664V |
| CTNNB1 | Activation of β-catenin signaling and its cross talk with estrogen and histone deacetylases in human uterine fibroids | J. Clin. Endocrinol. Metab. 2019 | Lenti | TL313664V |
| CTNNBL1 | Spliceosome-associated factor CTNNBL1 promotes proliferation and invasion in ovarian cancer | Exp. Cell Res. 2017 | Lenti | RC224836L1 |
| CTSB | Cathepsin-B-mediated cleavage of Disabled-2 regulates TGF-ß-induced autophagy | Nat. Cell Biol. 2016 | Lenti | TL305176 |
| CUX2 | MYCN amplification and ATRX mutations are incompatible in neuroblastoma | Nat Commun 2020 | Lenti | RC222063L4 |
| CXCL1 | Plac1 Is a Key Regulator of the Inflammatory Response and Immune Tolerance In Mammary Tumorigenesis | Sci Rep 2018 | Lenti | MR220966L1 |
| CXCL8 | IL-8 Activates Breast Cancer-Associated Adipocytes and Promotes Their Angiogenic and Tumorigenic Promoting Effects | Mol. Cell. Biol. 2018 | Lenti | TL319476 |
| CXCL8 | IL-8 Activates Breast Cancer-Associated Adipocytes and Promotes Their Angiogenic and Tumorigenic Promoting Effects | Mol. Cell. Biol. 2018 | Lenti | RC202075L1 |
| CXCR3 | Divergent roles of CXCR3 isoforms in promoting cancer stem-like cell survival and metastasis | Breast Cancer Res. Treat. Dec 2014 | Lenti | TL316563 |
| CXCR4 | CXCR4 uses STAT3-mediated slug expression to maintain radioresistance of non-small cell lung cancer cells: emerges as a potential prognostic biomarker for lung cancer | Cell death & disease 2021 | Lenti | TL313630 |
| CXCR4 | PECAM1 Combines With CXCR4 to Trigger Inflammatory Cell Infiltration and Pulpitis Progression Through Activating the NF-κB Signaling Pathway | Frontiers in Cell and Developmental Biology 2020 | Lenti | TL710583V |
| CXCR4 | m6A mRNA demethylase FTO regulates melanoma tumorigenicity and response to anti-PD-1 blockade | Nat Commun 2019 | Lenti | RC214548L2 |
| CXCR4 | Randomly distributed K14+ breast tumor cells polarize to the leading edge to direct collective migration in response to chemical and mechanical environmental cues | Cancer Res. 2019 | Lenti | TL500383 |
| CXCR4 | Epigenetic regulation of CXCL12 plays a critical role in mediating tumor progression and the immune response in osteosarcoma | Cancer Res. 2018 | Lenti | TL500383 |
| CXCR4 | Epigenetic regulation of CXCL12 plays a critical role in mediating tumor progression and the immune response in osteosarcoma | Cancer Res. 2018 | Lenti | TL313630 |
| CXCR4 | Proinflammatory CXCL12-CXCR4/CXCR7 signaling axis drives Myc-induced prostate cancer in obese mice | Cancer Res. 2017 | Lenti | TL500383 |
| CXCR7 | Proinflammatory CXCL12-CXCR4/CXCR7 signaling axis drives Myc-induced prostate cancer in obese mice | Cancer Res. 2017 | Lenti | TL515747 |
| CXCR7 | ShRNA knock-down of CXCR7 inhibits tumour invasion and metastasis in hepatocellular carcinoma after transcatheter arterial chemoembolization | J. Cell. Mol. Med. 2017 | Lenti | TL305345 |
| CXCR7 | Platelet-derived SDF-1 primes the pulmonary capillary vascular niche to drive lung alveolar regeneration | Nat. Cell Biol. Feb 2015 | Lenti | TL305345 |
| CXCR7 | Platelet-derived SDF-1 primes the pulmonary capillary vascular niche to drive lung alveolar regeneration | Nat. Cell Biol. Feb 2015 | Lenti | TL515747 |
| CYP1B1 | Cytochrome P450 1B1 inhibition suppresses tumorigenicity of prostate cancer via caspase-1 activation | Oncotarget 2017 | Lenti | TL313605 |
| DAB2 | Cathepsin-B-mediated cleavage of Disabled-2 regulates TGF-ß-induced autophagy | Nat. Cell Biol. 2016 | Lenti | TL313573 |
| DACH1 | Suppression of DACH1 promotes migration and invasion of colorectal cancer via activating TGF-ß-mediated epithelial-mesenchymal transition | Biochem. Biophys. Res. Commun. Mar 2015 | Lenti | TL313572 |
| DCLK1 | Saffron Crudes and Compounds Restrict MACC1-Dependent Cell Proliferation and Migration of Colorectal Cancer Cells | Cells 2020 | Lenti | RC217050L2 |
| DCN | Decorin knockdown affects the gene expression profile of adhesion, growth and extracellular matrix metabolism in C-28/I2 chondrocytes | PLoS ONE 2020 | Lenti | TL313548 |
| DDR2 | Targeting DDR2 in head and neck squamous cell carcinoma with dasatinib | Int. J. Cancer 2016 | Lenti | TL320440 |
| DDX41 | R-loop proximity proteomics identifies a role of DDX41 in transcription-associated genomic instability | Research Square 2021 | Lenti | TL305064 |
| DDX58 | RIG-I Promotes Cell Death in Hepatocellular Carcinoma by Inducing M1 Polarization of Perineal Macrophages Through the RIG-I/MAVS/NF-κB Pathway | OncoTargets and therapy 2020 | Lenti | MR226477L4V |
| DEPDC5 | Acute knockdown of Depdc5 leads to synaptic defects in mTOR-related epileptogenesis | Neurobiol. Dis. 2020 | Lenti | TL508165 |
| DHX32 | DEAH-box polypeptide 32 promotes hepatocellular carcinoma progression via activating the β-catenin pathway | Research Square 2020 | Lenti | RC209736L3V |
| DKK1 | Wnt signaling modulator DKK1 as an immunotherapeutic target in ovarian cancer | Gynecol. Oncol. 2020 | Lenti | MR203629L3 |
| DKK3 | DKK3 knockdown confers negative effects on the malignant potency of head and neck squamous cell carcinoma cells via the PI3K/Akt and MAPK signaling pathways | Int. J. Oncol. 2018 | Lenti | TL313463 |
| DLG2 | 11q Deletion or ALK Activity Curbs DLG2 Expression to Maintain an Undifferentiated State in Neuroblastoma | Cell Rep 2020 | Lenti | RC227175L4 |
| DLG2 | 11q Deletion or ALK Activity Curbs DLG2 Expression to Maintain an Undifferentiated State in Neuroblastoma | Cell Rep 2020 | Lenti | RC227175L4V |
| DLL3 | Near infrared photoimmunotherapy targeting DLL3 for small cell lung cancer | EBioMedicine 2020 | Lenti | RC200005L2V |
| DNAJB1 | FOXE3 contributes to Peters anomaly through transcriptional regulation of an autophagy-associated protein termed DNAJB1 | Nature Communications Apr 2016 | Lenti | TL313427 |
| DNM2 | Arp2/3 nucleates F-actin coating of fusing insulin granules in pancreatic β cells to control insulin secretion | J. Cell. Sci. 2020 | Lenti | RC223585L2 |
| DNMT1 | Targeted phosphoproteomics of the Ras signaling network reveal regulatory mechanisms mediated by oncogenic KRAS | bioRxiv 2019 | Lenti | RC226414L1 |
| DNMT1 | Epigenetic regulation of CXCL12 plays a critical role in mediating tumor progression and the immune response in osteosarcoma | Cancer Res. 2018 | Lenti | TL514641 |
| DNMT1 | Epigenetic regulation of CXCL12 plays a critical role in mediating tumor progression and the immune response in osteosarcoma | Cancer Res. 2018 | Lenti | TL313404 |
| DNMT1 | Cancer associated fibroblasts in pancreatic cancer are reprogrammed by tumor-induced alterations in genomic DNA methylation | Cancer Res. 2016 | Lenti | TL313404 |
| DNMT3A | Epigenetic regulation of CXCL12 plays a critical role in mediating tumor progression and the immune response in osteosarcoma | Cancer Res. 2018 | Lenti | TL500549 |
| DNMT3A | Epigenetic regulation of CXCL12 plays a critical role in mediating tumor progression and the immune response in osteosarcoma | Cancer Res. 2018 | Lenti | TL304938 |
| DOT1L | Targeting histone methyltransferase DOT1L by a novel psammaplin A analog inhibits growth and metastasis of triple-negative breast cancer | Molecular Therapy - Oncolytics 2019 | Lenti | RC218547L2 |
| DPYSL3 | Collapsin response mediator protein 4 enhances the radiosensitivity of colon cancer cells through calcium‑mediated cell signaling | Oncology Reports 2021 | Lenti | TL313373V |
| DPYSL3 | Collapsin response mediator protein 4 enhances radio-sensitivity through calcium-mediated cell signaling | Research Square 2020 | Lenti | TL313373V |
| DRAM1 | Overexpression of apoptosis-inducing factor mitochondrion-associated 1 (AIFM1) induces apoptosis by promoting the transcription of caspase3 and DRAM in hepatoma cells | Biochem. Biophys. Res. Commun. 2018 | Lenti | TL307117 |
| DRD2 | Antipsychotic drugs elicit cytotoxicity in glioblastoma multiforme in a calcium-dependent, non-D2 receptor-dependent, manner | Pharmacology research & perspectives 2021 | Lenti | RC202476L3V |
| DRD2 | The Dopamine D2 Receptor Contributes to the Spheroid Formation Behavior of U87 Glioblastoma Cells | Pharmacology 2019 | Lenti | RC213065L3V |
| DRD2 | Role of Dopamine Receptors in the Anticancer Activity of ONC201 | Neoplasia 2017 | Lenti | TL304907 |
| DSCAM | Origins and Proliferative States of Human Oligodendrocyte Precursor Cells | Cell 2020 | Lenti | TL304905V |
| DSP | Changes in mRNA/protein expression and signaling pathways in in vivo passaged mouse ovarian cancer cells | PLoS ONE 2018 | Lenti | TL519230 |
| DUSP23 | Profiling analysis of protein tyrosine phosphatases during neuronal differentiation | Neurosci. Lett. Dec 2015 | Lenti | TL317251 |
| DUSP5 | Dual specificity phosphatase 5 regulates perfusion recovery in experimental peripheral artery disease | Vasc Med 2019 | Lenti | TL518256 |
| E2F1 | Non-overlapping Control of Transcriptome by Promoter- and Super-Enhancer-Associated Dependencies in Multiple Myeloma | Cell Rep 2018 | Lenti | RC208247L2 |
| EBF2 | Heterogeneity in old fibroblasts is linked to variability in reprogramming and wound healing | Nature 2019 | Lenti | MR224591L3 |
| EDEM2 | Innate sensing of influenza A virus hemagglutinin glycoproteins by the host endoplasmic reticulum (ER) stress pathway triggers a potent antiviral response via ER-associated protein degradation | J. Virol. 2017 | Lenti | TL304849 |
| EFEMP1 | The matrix protein Fibulin-3 promotes KISS1R induced triple negative breast cancer cell invasion | Oncotarget 2018 | Lenti | TL313284 |
| EGFL7 | Attenuation of EGFL7 expression inhibits growth hormone-producing pituitary adenomas growth and invasion | Hum. Gene Ther. 2018 | Lenti | TL508528 |
| EGFL7 | EGFL7 participates in regulating biological behavior of growth hormone-secreting pituitary adenomas via Notch2/DLL3 signaling pathway | Tumour Biol. 2017 | Lenti | TL713010 |
| EGFR | EGFR signaling confers resistance to BET inhibition in hepatocellular carcinoma through stabilizing oncogenic MYC | J. Exp. Clin. Cancer Res. 2019 | Lenti | TL320326 |
| EGFR | Activation of EGFR/p38/HIF-1a is pivotal for angiogenesis and tumorigenesis of malignantly transformed cells induced by hexavalent chromium | J. Biol. Chem. May 2016 | Lenti | TL320326 |
| EGR1 | Early growth response 1 regulates hematopoietic support and proliferation in human primary bone marrow stromal cells | Haematologica 2019 | Lenti | TL313277 |
| EIF2S1 | Activation of the eIF2α/ATF4 axis drives triple-negative breast cancer radioresistance by promoting glutathione biosynthesis | Redox Biology 2021 | Lenti | RC200368L3V |
| EIF3F | Nuclear control of lung cancer cells migration, invasion and bioenergetics by eukaryotic translation initiation factor 3F | Oncogene 2019 | Lenti | RC201740L3 |
| EIF4E | Activation of Tyrosine Metabolism in CD13+ Cancer Stem Cells Drives Relapse in Hepatocellular Carcinoma | Cancer Res Treat 2019 | Lenti | TL313244 |
| EMSY | EMSY expression affects multiple components of skin barrier with relevance to atopic dermatitis | Journal of Allergy and Clinical Immunology 2019 | Lenti | RC216916L4 |
| ENG | Inhibition of endoglin exerts anti-tumor effects through the regulation of non-Smad TGF-β signaling in angiosarcoma | J. Invest. Dermatol. 2020 | Lenti | RC221699L1V |
| ENO1 | Dominant role of CDKN2B/p15INK4B of 9p21.3 tumor suppressor hub in inhibition of cell-cycle and glycolysis | Nature communications 2021 | Lenti | TL313211 |
| EP300 | Histone Acetyltransferase p300 Induces De Novo Super-Enhancers to Drive Cellular Senescence | Mol. Cell 2019 | Lenti | RC223265L1 |
| EPAS1 | miR-147b-mediated TCA cycle dysfunction and pseudohypoxia initiate drug tolerance to EGFR inhibitors in lung adenocarcinoma | Nat Metab 2019 | Lenti | TL315484 |
| EPGN | Regulation of Collective Metastasis by Nanolumenal Signaling | Cell 2020 | Lenti | RC214501L4 |
| EPGN | Regulation of Collective Metastasis by Nanolumenal Signaling | Cell 2020 | Lenti | MR219218L4 |
| ERA | Modulation effects of black-vinegar based supplement against a high-fat dietary habit: antiobesity/hypolipidemic, antioxidative, and energy-metabolism effects | J. Sci. Food Agric. 2020 | Lenti | TL510613 |
| ERBB2 | Tuning the Antigen Density Requirement for CAR T Cell Activity | Cancer Discov 2020 | Lenti | RC212583L1 |
| ERBB2 | The S100A4 Protein Signals through the ErbB4 Receptor to Promote Neuronal Survival | Theranostics 2018 | Lenti | TL709823 |
| ERBB2 | Directed Evolution of Scanning Unnatural-Protease-Resistant (SUPR) Peptides for in Vivo Applications | Chembiochem 2016 | Lenti | TL320342 |
| ERBB2 | Transmembrane Domain Targeting Peptide Antagonizing ErbB2/Neu Inhibits Breast Tumor Growth and Metastasis | Cell Rep Sep 2014 | Lenti | TL320342 |
| ERCC2 | ERCC2 Helicase Domain Mutations Confer Nucleotide Excision Repair Deficiency and Drive Cisplatin Sensitivity in Muscle-Invasive Bladder Cancer | Clin. Cancer Res. 2018 | Lenti | RC215058L1 |
| ERCC2 | XPD localizes in mitochondria and protects the mitochondrial genome from oxidative DNA damage | Nucleic Acids Res. May 2015 | Lenti | TL313180 |
| ERCC4 | A Unique Subset of Epithelial Ovarian Cancers with Platinum Sensitivity and PARP Inhibitor Resistance | Cancer Res. Feb 2015 | Lenti | RC223300L1 |
| ERCC6 | Elevated Expression of ERCC6 Confers Resistance to 5-Fluorouracil and Is Associated with Poor Patient Survival in Colorectal Cancer | DNA Cell Biol. 2017 | Lenti | TL313176 |
| ESR1 | 17β-estradiol binding to ERα promotes the progression of prolactinoma through estrogen-response element-induced CaBP-9k up-regulation | Biosci. Rep. 2020 | Lenti | TL510613 |
| ESR1 | Estrogen receptors orchestrate cell growth and differentiation to facilitate liver regeneration | Theranostics 2018 | Lenti | RC213277L2 |
| ESR1 | PAC down-regulates estrogen receptor alpha and suppresses epithelial-to-mesenchymal transition in breast cancer cells | BMC Cancer 2016 | Lenti | TL320346 |
| ESR2 | Estrogen receptors orchestrate cell growth and differentiation to facilitate liver regeneration | Theranostics 2018 | Lenti | RC218519L2 |
| ESRRA | NURR1 and ERR1 Modulate the Expression of Genes of a DRD2 Coexpression Network Enriched for Schizophrenia Risk | J. Neurosci. 2020 | Lenti | MR225753L1 |
| ESRRA | NURR1 and ERR1 Modulate the Expression of Genes of a DRD2 Coexpression Network Enriched for Schizophrenia Risk | J. Neurosci. 2020 | Lenti | TL502583 |
| ETS1 | ETS1 Suppresses Tumorigenesis of Human Breast Cancer via Trans-Activation of Canonical Tumor Suppressor Genes | Front Oncol 2020 | Lenti | RC215203L2 |
| ETS1 | ETS1 Suppresses Tumorigenesis of Human Breast Cancer via Trans-Activation of Canonical Tumor Suppressor Genes | Front Oncol 2020 | Lenti | TL313153 |
| EZH2 | A non-canonical function of Ezh2 preserves immune homeostasis | EMBO Rep 2017 | Lenti | RC202054L1 |
| EZH2 | Long noncoding RNA H19 regulates EZH2 expression by interacting with miR-630 and promotes cell invasion in nasopharyngeal carcinoma | Biochem. Biophys. Res. Commun. May 2016 | Lenti | TL304713 |
| EZH2 | Sunitinib dose-escalation overcomes transient resistance in clear cell renal cell carcinoma and is associated with epigenetic modifications | Mol. Cancer Ther. Dec 2014 | Lenti | TL304713 |
| FAM50B | Combinatorial CRISPR screen identifies fitness effects of gene paralogues | Nature communications 2021 | Lenti | RC201531L3 |
| FANCI | CTDP1 regulates breast cancer survival and DNA repair through BRCT-specific interactions with FANCI | Cell Death Discov 2019 | Lenti | RC226384L4 |
| FBL | Inhibition of Dopamine Receptor D4 Impedes Autophagic Flux, Proliferation, and Survival of Glioblastoma Stem Cells | Cancer Cell Jun 2016 | Lenti | TL313054 |
| FBLN2 | Correlation of Fibulin‑2 expression with proliferation, migration and invasion of breast cancer cells | Oncol Lett 2020 | Lenti | RC218622L3 |
| FBXW7 | F-Box/WD Repeat Domain-Containing 7 Induces Chemotherapy Resistance in Colorectal Cancer Stem Cells | Cancers (Basel) 2019 | Lenti | TL304541 |
| FERMT2 | The focal adhesion protein kindlin-2 controls mitotic spindle assembly by inhibiting histone deacetylase 6 and maintaining α-tubulin acetylation | J. Biol. Chem. 2020 | Lenti | TL310359 |
| Fgf15 | A Genetic Screen Identifies Hypothalamic Fgf15 as a Regulator of Glucagon Secretion | Cell Rep 2016 | Lenti | TL514099 |
| FGFR3 | Modulation of HCV reinfection after orthotopic liver transplantation by fibroblast growth factor-2 and other non-interferon mediators | Gut Mar 2015 | Lenti | RC215533L2 |
| FLT1 | Injured Axons Instruct Schwann Cells to Build Constricting Actin Spheres to Accelerate Axonal Disintegration | Cell Rep 2019 | Lenti | RC224406L2 |
| FLT3 | Human Cytomegalovirus UL7, miR-US5-1, and miR-UL112-3p Inactivation of FOXO3a Protects CD34+ Hematopoietic Progenitor Cells from Apoptosis | mSphere 2021 | Lenti | RC211459L4V |
| FMR1 | Fragile X mental retardation protein in intrahepatic cholangiocarcinoma: regulating the cancer cell behavior plasticity at the leading edge | Oncogene 2021 | Lenti | TL312955 |
| FN1 | Fibronectin 1 promotes migration and invasion of papillary thyroid cancer and predicts papillary thyroid cancer lymph node metastasis | Onco Targets Ther 2017 | Lenti | TL304489 |
| FOLR1 | Anti-Folate Receptor alpha-directed Antibody Therapies Restrict the Growth of Triple Negative Breast Cancer | Clin. Cancer Res. 2018 | Lenti | TL304479 |
| FOLR1 | Modification of cytokine-induced killer cells with folate receptor alpha (FRα)-specific chimeric antigen receptors enhances their antitumor immunity toward FRα-positive ovarian cancers | Mol. Immunol. 2017 | Lenti | RC221050L1 |
| FOLR2 | Targeting of folate receptor-beta on acute myeloid leukemia blasts with chimeric antigen receptor expressing T cells | Blood Apr 2015 | Lenti | RC212993L1 |
| FOS | Nkx6.1-mediated insulin secretion and ß-cell proliferation is dependent on upregulation of c-Fos | FEBS Lett. May 2016 | Lenti | TL710577 |
| FOSL1 | The histone deacetylase inhibitor LBH589 inhibits undifferentiated pleomorphic sarcoma growth via downregulation of FOS-like antigen 1 | Mol. Carcinog. 2018 | Lenti | RC202104L2 |
| FOXA3 | Estrogen receptors orchestrate cell growth and differentiation to facilitate liver regeneration | Theranostics 2018 | Lenti | RC202363L2 |
| FOXC1 | Oct4-dependent FoxC1 Activation Improves the Survival and Neovascularization of Mesenchymal Stem Cells under Myocardial Ischemia | Research Square 2021 | Lenti | TL513221V |
| FOXD3 | Activation of Tyrosine Metabolism in CD13+ Cancer Stem Cells Drives Relapse in Hepatocellular Carcinoma | Cancer Res Treat 2019 | Lenti | TL312939 |
| FOXF1 | Forkhead box F1 induces columnar phenotype and epithelial-to-mesenchymal transition in esophageal squamous cells to initiate Barrett\'s like metaplasia | Laboratory investigation; a journal of technical methods and pathology 2021 | Lenti | RC218259L2V |
| FOXO3 | Mitochondrial FOXO3a is involved in amyloid ß peptide-induced mitochondrial dysfunction | J. Bioenerg. Biomembr. Jan 2016 | Lenti | TL704976 |
| FSCN1 | Fascin is Critical for the Maintenance of Breast Cancer Stem Cell Pool Predominantly via the Activation of the Notch Self-Renewal Pathway | Stem Cells 2016 | Lenti | TL312916 |
| FTO | FTO-Dependent N6-Methyladenosine Modifications Inhibit Ovarian Cancer Stem Cell Self-Renewal by Blocking cAMP Signaling | Cancer Res. 2020 | Lenti | TL308064 |
| FTO | FTO-mediated cytoplasmic m6Am demethylation adjusts stem-like properties in colorectal cancer cell | bioRxiv 2020 | Lenti | TL308064 |
| FTO | The m6A eraser FTO facilitates proliferation and migration of human cervical cancer cells | Cancer Cell Int. 2019 | Lenti | TL308064 |
| FTO | R-2HG Exhibits Anti-tumor Activity by Targeting FTO/m6A/MYC/CEBPA Signaling | Cell 2018 | Lenti | TL308064 |
| FTO | Kaposi's Sarcoma-Associated Herpesvirus Utilizes and Manipulates RNA N6-Adenosine Methylation To Promote Lytic Replication | J. Virol. 2017 | Lenti | TL308064 |
| FTO | FTO Plays an Oncogenic Role in Acute Myeloid Leukemia as a N(6)-Methyladenosine RNA Demethylase | Cancer Cell 2016 | Lenti | TL308064 |
| FUS | Senataxin mutations elicit motor neuron degeneration phenotypes and yield TDP-43 mislocalization in ALS4 mice and human patients | Acta Neuropathol. 2018 | Lenti | RC201808L2 |
| FZD4 | Norrin mediates tumor-promoting and -suppressive effects in glioblastoma via Notch and WNT | J. Clin. Invest. 2020 | Lenti | RC217286L1 |
| FZD4 | Norrin mediates tumor-promoting and -suppressive effects in glioblastoma via Notch and WNT | J. Clin. Invest. 2020 | Lenti | TL312883 |
| FZD4 | Wnt5a/FZD4 Mediates the Mechanical Stretch-Induced Osteogenic Differentiation of Bone Mesenchymal Stem Cells | Cell. Physiol. Biochem. 2018 | Lenti | TL500740 |
| FZD5 | ARID3B Directly Regulates Ovarian Cancer Promoting Genes | PLoS ONE Jun 2015 | Lenti | RC213960L2 |
| GAB2 | Gab2 Ablation Reverses the Stemness of HER2-Overexpressing Breast Cancer Cells | Cell. Physiol. Biochem. 2018 | Lenti | TL312875 |
| GABRG2 | Shifting hippocampal excitation/inhibition balance modifies despair-like behavior in mice | bioRxiv 2020 | Lenti | TL515175 |
| GABRG2 | Hippocampal GABA-inhibitory circuitry regulates despair-like behavior in mice | bioRxiv 2020 | Lenti | TL515175 |
| GAPDH | Glucose Response by Stem Cell-Derived β Cells In Vitro Is Inhibited by a Bottleneck in Glycolysis | Cell Rep 2020 | Lenti | RC202309L1 |
| GATA1 | The Il9 CNS-25 Regulatory Element Controls Mast Cell and Basophil IL-9 Production | J. Immunol. 2019 | Lenti | TL500772 |
| GATA4 | Myocyte-specific enhancer factor 2c triggers transdifferentiation of adipose tissue-derived stromal cells into spontaneously beating cardiomyocyte-like cells | Scientific reports 2021 | Lenti | MR227022L4V |
| GATA4 | Meox1 accelerates myocardial hypertrophic decompensation through Gata4 | Cardiovasc. Res.2017 | Lenti | TL500773 |
| GBP5 | Guanylate Binding Protein 5 (GBP5) regulates synovial fibroblast mediated inflammation and tissue destruction in rheumatoid arthritis | Arthritis & Rheumatology 2020 | Lenti | RC225986L2V |
| GCC2 | Evaluation of TAK-264, an Antibody-Drug Conjugate in Pancreatic Cancer Cell Lines and Patient-Derived Xenograft Models | Clin Cancer Drugs 2018 | Lenti | TL312820 |
| GCK | Glucose-dependent partitioning of arginine to the urea cycle protects β-cells from inflammation | Nat Metab 2020 | Lenti | RC200472L1 |
| GDF15 | Subregional differences in astrocytes underlie selective neurodegeneration or protection in Parkinson's disease models in culture | Glia 2019 | Lenti | TL710232 |
| GFAT1 | Enhanced hexosamine metabolism drives metabolic and signaling networks involving hyaluronan production and O-GlcNAcylation to exacerbate breast cancer | Cell Death Dis 2019 | Lenti | TL511601V |
| GFPT1 | Hyperglycemia exacerbates colon cancer malignancy through hexosamine biosynthetic pathway | Oncogenesis 2017 | Lenti | TL511601 |
| GLUL | Glutamine synthetase activity fuels nucleotide biosynthesis and supports growth of glutamine-restricted glioblastoma | Nat. Cell Biol. Dec 2015 | Lenti | TL312740 |
| GMNN | Geminin deletion increases the number of fetal hematopoietic stem cells by affecting the expression of key transcription factors | Development Jan 2015 | Lenti | TL304304 |
| GOLPH3 | Lentivirus Mediated GOLPH3 shRNA Inhibits Growth and Metastasis of Esophageal Squamous Cancer | Asian Pac. J. Cancer Prev. 5391-6 Nov 2013 | Lenti | TL317415 |
| GORASP2 | Grasp55-/- mice display impaired fat absorption and resistance to high-fat diet-induced obesity | Nat Commun 2020 | Lenti | RC202946L3 |
| GORASP2 | Alternative splicing switches STIM1 targeting to specialized membrane contact sites and modifies SOCE | bioRxiv 2020 | Lenti | RC202946L3 |
| GPAM | Glycerol-3-phosphate is a FGF23 regulator derived from the injured kidney | J. Clin. Invest. 2020 | Lenti | TL500848V |
| GPAT4 | Glycerol-3-phosphate is a FGF23 regulator derived from the injured kidney | J. Clin. Invest. 2020 | Lenti | TL512820V |
| GPR158 | Gpr158 mediates osteocalcin's regulation of cognition | J. Exp. Med. 2017 | Lenti | TL509693 |
| GPRC5A | Orphan G protein-coupled receptor GPRC5A modulates integrin ß1-mediated epithelial cell adhesion | Cell Adh Migr 2016 | Lenti | RC200118L1 |
| GRHL2 | Porphyromonas gingivalis Impairs Oral Epithelial Barrier through Targeting GRHL2 | J. Dent. Res. 2019 | Lenti | TL304206 |
| GRHL2 | Grainyhead-like 2 (GRHL2) knockout abolishes oral cancer development through reciprocal regulation of the MAP kinase and TGF-β signaling pathways | Oncogenesis 2018 | Lenti | TL304206 |
| GRIN2B | Synaptic proximity enables NMDAR signalling to promote brain metastasis | Nature 2019 | Lenti | RC223623L2 |
| GRK5 | GRK5 is an Essential Co-repressor for Cardiac Mineralocorticoid Receptor Antagonism induced by Finerenone but not Eplerenone | preprints 2020 | Lenti | RC209137L4V |
| GRSF1 | Loss of RNA-binding protein GRSF1 activates mTOR to elicit a proinflammatory transcriptional program | Nucleic Acids Res. 2019 | Lenti | TL312593 |
| GRSF1 | GRSF1 suppresses cell senescence | Aging (Albany NY) 2018 | Lenti | TL312593V |
| GSTA2 | Glutathione S-transferase A2 (GSTA2) Promotes Hepatocellular Carcinoma Recurrence After Liver Transplantation Through Modulating Reactive Oxygen Species Metabolism | Research Square 2020 | Lenti | RC202479L2 |
| Gucy1a3 | Reciprocal regulation between O-GlcNAcylation and tribbles pseudokinase 2 (TRIB2) maintains transformative phenotypes in liver cancer cells | Cell. Signal. 2016 | Lenti | MR210068L1 |
| GUCY2C | A Novel GUCY2C-CD3 T cell Engaging Bispecific construct (PF-07062119) for the Treatment of Gastrointestinal Cancers | Clin. Cancer Res. 2020 | Lenti | RC213901L3 |
| GULP1 | GULP1 regulates the NRF2-KEAP1 signaling axis in urothelial carcinoma | Sci Signal 2020 | Lenti | TL304167 |
| GULP1 | Integrated transcriptomic and epigenomic analysis of ovarian cancer reveals epigenetically silenced GULP1 | Cancer Lett. 2018 | Lenti | TL304167 |
| GYS1 | Restoring metabolism of myeloid cells reverses cognitive decline in ageing | Nature 2021 | Lenti | TL312546 |
| H19 | LncRNA H19 downregulation confers erlotinib resistance through upregulation of PKM2 and phosphorylation of AKT in EGFR-mutant lung cancers | Cancer Lett. 2020 | Lenti | TL318197 |
| H19 | Long noncoding RNA H19 regulates EZH2 expression by interacting with miR-630 and promotes cell invasion in nasopharyngeal carcinoma | Biochem. Biophys. Res. Commun. May 2016 | Lenti | TL318197 |
| HADHA | Targeting the mitochondrial trifunctional protein restrains tumor growth in oxidative lung carcinomas | The Journal of clinical investigation 2021 | Lenti | TL312528V |
| HAT1 | HAT1 Coordinates Histone Production and Acetylation via H4 Promoter Binding | Molecular Cell 2019 | Lenti | RC209571L1 |
| HAT1 | HAT1 Coordinates Histone Production and Acetylation via H4 Promoter Binding | Molecular Cell 2019 | Lenti | TL312517 |
| HAVCR1 | Kidney injury molecule-1 inhibits metastasis of renal cell carcinoma | Scientific reports 2021 | Lenti | MR203831L3V |
| HAVCR1 | Recombinant apoptosis inhibitor of macrophage protein reduces delayed graft function in a murine model of kidney transplantation | PloS one 2021 | Lenti | MR203831L3 |
| HBP1 | UHRF1 regulates the transcriptional repressor HBP1 through MIF in T acute lymphoblastic leukemia | Oncology reports 2021 | Lenti | TL312507 |
| HBP1 | ICBP90 Regulates MIF Expression, Glucocorticoid Sensitivity, and Apoptosis at the , MIF Immune Susceptibility Locus | Arthritis & rheumatology (Hoboken, N.J.) 2021 | Lenti | TL312507 |
| HBP1 | Transcription factor ICBP90 regulates the MIF promoter and immune susceptibility locus | J. Clin. Invest. Feb 2016 | Lenti | TL312507 |
| HC | MK801 regulates the expression of key osteoarthritis factors in osteoarthritis synovial fibroblasts through complement C5 | Research in Veterinary Science 2021 | Lenti | TL511576 |
| HDAC2 | Ethanol exposure regulates Gabra1 expression via histone deacetylation at the promoter in cultured cortical neurons | J. Pharmacol. Exp. Ther. 2017 | Lenti | TL711866 |
| HDAC4 | HDAC4: a key factor underlying brain developmental alterations in CDKL5 disorder | Hum. Mol. Genet. 2016 | Lenti | TL510852 |
| HDAC6 | Rational cotargeting of HDAC6 and BET proteins yields synergistic antimyeloma activity | Blood Adv 2019 | Lenti | RC209649L4V |
| HDGF | A novel SNP in the 5' regulatory region of organic anion transporter 1 is associated with chronic kidney disease | Sci Rep 2018 | Lenti | RC204148L1 |
| HEY1 | Reciprocal activation of HEY1 and NOTCH4 under SOX2 control promotes EMT in head and neck squamous cell carcinoma | International Journal of Oncology 2020 | Lenti | RC200257L3 |
| HEY2 | Defining human cardiac transcription factor hierarchies using integrated single-cell heterogeneity analysis | Nat Commun 2018 | Lenti | RC202544L2 |
| HGF | New Paradigms to Assess Consequences of Long-Term, Low-Dose Curcumin Exposure in Lung Cancer Cells | Molecules 2020 | Lenti | TL312467 |
| HIF1A | Sulforaphane Inhibits Nonmuscle Invasive Bladder Cancer Cells Proliferation through Suppression of HIF-1α-Mediated Glycolysis in Hypoxia | J. Agric. Food Chem. 2019 | Lenti | TL320380 |
| HIF1A | miR-147b-mediated TCA cycle dysfunction and pseudohypoxia initiate drug tolerance to EGFR inhibitors in lung adenocarcinoma | Nat Metab 2019 | Lenti | TL320380 |
| HIF1A | A facile in vitro platform to study cancer cell dormancy under hypoxic microenvironments using CoCl2 | J Biol Eng 2018 | Lenti | TL320380 |
| HIF1A | Activation of EGFR/p38/HIF-1a is pivotal for angiogenesis and tumorigenesis of malignantly transformed cells induced by hexavalent chromium | J. Biol. Chem. May 2016 | Lenti | TL320380 |
| HIF1A | Cell type-dependent modulation of the gene encoding heat shock protein HSPA2 by hypoxia-inducible factor HIF-1: Down-regulation in keratinocytes and up-regulation in HeLa cells | Biochim. Biophys. Acta Jul 2015 | Lenti | TL320380 |
| HIPK1 | Mapping effector genes at lupus GWAS loci using promoter Capture-C in follicular helper T cells | Nat Commun 2020 | Lenti | TL320769 |
| HIPK1 | Human follicular helper T cell promoter connectomes reveal novel genes and regulatory elements at SLE GWAS loci | bioRxiv 2019 | Lenti | TL320769 |
| HMGB1 | High mobility group box 1 promotes sorafenib resistance in HepG2 cells and in vivo | BMC Cancer 2017 | Lenti | RC205918L2 |
| HMGCR | Inhibition of cholesterol biosynthesis overcomes enzalutamide resistance in castration-resistant prostate cancer (CRPC) | J. Biol. Chem. 2018 | Lenti | TL312393 |
| HMOX1 | Synthetically Lethal Interactions of Heme Oxygenase-1 and Fumarate Hydratase Genes | Biomolecules 2020 | Lenti | TL312388 |
| HMOX1 | Atorvastatin and Conditioned Media from Atorvastatin-Treated Human Hematopoietic Stem/Progenitor-Derived Cells Show Proangiogenic Activity In Vitro but Not In Vivo | Mediators of Inflammation 2019 | Lenti | TL500966 |
| Hmox1 | Bacteroides fragilis Enterotoxin Upregulates Heme Oxygenase-1 in Intestinal Epithelial Cells via a Mitogen-Activated Protein Kinases- and NF-?B-Dependent Pathway, Leading to Modulation of Apoptosis | Infect. Immun. Jun 2016 | Lenti | MR203944L1 |
| HNF1A | Decreased GLUT2 and glucose uptake contribute to insulin secretion defects in MODY3/HNF1A hiPSC-derived mutant β cells | Nature communications 2021 | Lenti | RC211201L2 |
| HNF1A | Estrogen receptors orchestrate cell growth and differentiation to facilitate liver regeneration | Theranostics 2018 | Lenti | RC211201L2 |
| HNF1A | Aberrant Activation of a Gastrointestinal Transcriptional Circuit in Prostate Cancer Mediates Castration Resistance | Cancer Cell 2017 | Lenti | RC211201L1 |
| HNF4A | Estrogen receptors orchestrate cell growth and differentiation to facilitate liver regeneration | Theranostics 2018 | Lenti | RC217863L2 |
| Hnf4a | Hepatocyte Nuclear Factor-4 alpha in Noise-Induced Cochlear Neuropathy | Dev Neurobiol Apr 2016 | Lenti | TL500970 |
| HNF4G | miR-34a Inhibits Proliferation and Invasion of Bladder Cancer Cells by Targeting Orphan Nuclear Receptor HNF4G | Disease Markers Mar 2015 | Lenti | RC219703L2 |
| HNRNPA1 | Genome-wide analysis of pseudogenes reveals HBBP1\'s human-specific essentiality in erythropoiesis and implication in β-thalassemia | Developmental cell 2021 | Lenti | TL312381 |
| HNRNPD | The inflammatory/cancer-related IL-6/STAT3/NF-?B positive feedback loop includes AUF1 and maintains the active state of breast myofibroblasts | Oncotarget 2016 | Lenti | RC201796L2 |
| HNRNPD | The Cytokine IL-6 Reactivates Breast Stromal Fibroblasts through Transcription Factor STAT3-dependent Up-regulation of the RNA Binding Protein AUF1 | J. Biol. Chem. Sep 2014 | Lenti | RC201796L1 |
| HOXA13 | CDH17 is a downstream effector of HOXA13 in modulating the Wnt/β-catenin signaling pathway in gastric cancer | Eur Rev Med Pharmacol Sci 2017 | Lenti | RC209698L1 |
| HOXA9 | Analysis of HOX gene expression and the effects of HOXA9 overexpression in fibroblasts derived from keloid lesions and normal skin | Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2021 | Lenti | RC200559L2V |
| HOXB9 | A miR-192-EGR1-HOXB9 regulatory network controls the angiogenic switch in cancer | Nat Commun Apr 2016 | Lenti | RC213735L2 |
| HOXC13 | Transcriptional regulation of the proto-oncogene Zfp521 by SPI1 (PU.1) and HOXC13 | Genesis 2016 | Lenti | TL304059 |
| HOXD10 | Homeobox D10, a tumor suppressor, inhibits the proliferation and migration of esophageal squamous cell carcinoma | J. Cell. Biochem. 2019 | Lenti | RC210208L3 |
| HPSE | Sphingosine-1-phosphate induced epithelial-mesenchymal transition of hepatocellular carcinoma via an MMP-7/ syndecan-1/TGF-ß autocrine loop | Oncotarget 2016 | Lenti | TL307138 |
| HSF1 | C/EBPβ is a key transcription factor for APOE and preferentially mediates ApoE4 expression in Alzheimer\'s disease | Molecular psychiatry 2020 | Lenti | TL312318 |
| HSF1 | C/EBPβ regulates delta-secretase expression and mediates pathogenesis in mouse models of Alzheimer's disease | Nat Commun 2018 | Lenti | TL312318 |
| HSPA5 | ER stress sensor, glucose regulatory protein 78 (GRP78) regulates redox status in pancreatic cancer thereby maintaining "stemness" | Cell Death Dis 2019 | Lenti | TL312303 |
| HSPA5 | ER translocation of the MAPK pathway drives therapy resistance in BRAF mutant melanoma | Cancer Discov 2018 | Lenti | TL500881 |
| HSPA5 | Mahanine drives pancreatic adenocarcinoma cells into endoplasmic reticular stress-mediated apoptosis through modulating sialylation process and Ca2+-signaling | Sci Rep 2018 | Lenti | TL312303 |
| HSPA9 | HSPA9/Mortalin Mediates Axo-Protection by Modulating Mitochondrial Dynamics in Neurons | Research Square 2020 | Lenti | TL704140 |
| HSPB2 | Schisandrin B ameliorates high glucose-induced vascular endothelial cells injury by regulating Noxa/Hsp27/NF-κB signaling pathway | Biochem. Cell Biol. 2019 | Lenti | TL312300 |
| HYAL4 | A Novel Splice Variant of HYAL-4 Drives Malignant Transformation and Predicts Outcome in Bladder Cancer Patients | Clin. Cancer Res. 2020 | Lenti | TL312276 |
| ICAM-5 | ICAM-5/Telencephalin Is a Functional Entry Receptor for Enterovirus D68 | Cell Host & Microbe 2016 | Lenti | TL312266 |
| ICAM1 | CD31 (PECAM-1) Serves as the Endothelial Cell-Specific Receptor of Clostridium perfringens β-Toxin | Cell Host & Microbe 2020 | Lenti | MR227081L4 |
| ICAM1 | Cell-specific targeting by Clostridium perfringens β-toxin unraveled: the role of CD31 as the toxin receptor | bioRxiv 2019 | Lenti | RC200714L3 |
| ICOSLG | Non-immune cell-derived ICOS ligand functions as a renoprotective αvβ3 integrin-selective antagonist | J. Clin. Invest. 2019 | Lenti | RC208975L2 |
| ICOSLG | Non-immune cell-derived ICOS ligand functions as a renoprotective αvβ3 integrin-selective antagonist | J. Clin. Invest. 2019 | Lenti | TL303997 |
| IDO1 | Targeting the kynurenine pathway for the treatment of cisplatin resistant lung cancer | Mol. Cancer Res. 2019 | Lenti | TL312147 |
| IDO1 | Tumor-Repopulating Cells Induce PD-1 Expression in CD8+T Cells by Transferring Kynurenine and AhR Activation | Cancer Cell 2018 | Lenti | TL511273 |
| IDO1 | Blockade of IDO-kynurenine-AhR metabolic circuitry abrogates IFN-γ-induced immunologic dormancy of tumor-repopulating cells | Nat Commun 2017 | Lenti | RC206592L1 |
| IDO1 | Blockade of IDO-kynurenine-AhR metabolic circuitry abrogates IFN-γ-induced immunologic dormancy of tumor-repopulating cells | Nat Commun 2017 | Lenti | TL312147 |
| IFIH1 | ISG15-dependent activation of the sensor MDA5 is antagonized by the SARS-CoV-2 papain-like protease to evade host innate immunity | Nature microbiology 2021 | Lenti | TL303992V |
| IGF1R | Pharmacological Inhibition of Insulin Growth Factor-1 Receptor (IGF-1R) Alone or in Combination With Ruxolitinib Shows Therapeutic Efficacy in Preclinical Myeloproliferative Neoplasm Models | HemaSphere 2021 | Lenti | TL320384 |
| IGFBP2 | IGFBP2 protects against pulmonary fibrosis through inhibiting P21-mediated senescence | bioRxiv 2021 | Lenti | MR204287L3V |
| IGFIR | The insulin-like growth factor I receptor regulates glucose transport by astrocytes | Glia 2016 | Lenti | TL501056 |
| IKZF1 | Transcriptional Regulation of PIK3CD and PIKFYVE in T-Cell Acute Lymphoblastic Leukemia by IKAROS and Protein Kinase CK2 | International journal of molecular sciences 2021 | Lenti | TL308127 |
| IL-37 | Interleukin-37 suppresses the osteogenic responses of human aortic valve interstitial cells in vitro and alleviates valve lesions in mice | Proc. Natl. Acad. Sci. U.S.A 2017 | Lenti | TL303957 |
| Il27 | Targeting Interleukin(IL)-30/IL-27p28 signaling in cancer stem-like cells and host environment synergistically inhibits prostate cancer growth and improves survival | J Immunother Cancer 2019 | Lenti | TL507534 |
| IL6 | Antitumor and Anti-Invasive Effect of Apigenin on Human Breast Carcinoma through Suppression of IL-6 Expression | Int J Mol Sci 2019 | Lenti | TL312162 |
| IL6 | Targeting Interleukin-6 (IL-6) Sensitizes Anti-PD-L1 Treatment in a Colorectal Cancer Preclinical Model | Med. Sci. Monit. 2018 | Lenti | MR227281L2 |
| IL6R | Metformin inhibits IL-6 signaling by decreasing IL-6R expression on multiple myeloma cells | Leukemia 2019 | Lenti | TL312161 |
| INA | a-Internexin and Peripherin: Expression, Assembly, Functions, and Roles in Disease | Methods in Enzymology Nov 2015 | Lenti | RC202877L2 |
| INA | a-Internexin and Peripherin: Expression, Assembly, Functions, and Roles in Disease | Methods in Enzymology Nov 2015 | Lenti | MR208054L2 |
| INA | a-Internexin and Peripherin: Expression, Assembly, Functions, and Roles in Disease | Methods in Enzymology Nov 2015 | Lenti | RR215311L2 |
| INPP4B | INPP4B exerts a dual function in the stemness of colorectal cancer stem-like cells through regulating Sox2 and Nanog expression | Carcinogenesis 2019 | Lenti | TL312138 |
| IRS4 | Pan-cancer analysis of somatic copy-number alterations implicates IRS4 and IGF2 in enhancer hijacking | Nat. Genet. 2016 | Lenti | RC218385L1 |
| ISG15 | ISG15-dependent activation of the sensor MDA5 is antagonized by the SARS-CoV-2 papain-like protease to evade host innate immunity | Nature microbiology 2021 | Lenti | TL319471V |
| ITGA2 | CD49b inhibits osteogenic differentiation and plays an important role in osteosarcoma progression | Oncotarget 2017 | Lenti | RC212617L1 |
| ITGA5 | O-GlcNAcylation of ITGA5 facilitates the occurrence and development of colorectal cancer | Exp. Cell Res. 2019 | Lenti | TL312094 |
| ITGAM | Microglial complement receptor 3 regulates brain Aß levels through secreted proteolytic activity | J. Exp. Med 2017 | Lenti | TL501116 |
| ITGB5 | αvβ5 integrin mediates the effect of vitronectin on the initial stage of differentiation in mouse cerebellar granule cell precursors | Brain Res. 2018 | Lenti | TL516440 |
| ITGB5 | αvβ5 integrin mediates the effect of vitronectin on the initial stage of differentiation in mouse cerebellar granule cell precursors | Brain Res. 2018 | Lenti | MR222893L1 |
| JAK1 | IGHG1 functions as an oncogene in tongue squamous cell carcinoma via JAK1/STAT5 signaling | European Review for Medical and Pharmacological Sciences 2020 | Lenti | TL320394 |
| JARID2 | Jarid2 enhances the progression of bladder cancer through regulating PTEN/AKT signaling | Life Sci. 2019 | Lenti | TL312055 |
| JMJD6 | Elevated expression of JMJD6 is associated with oral carcinogenesis and maintains cancer stemness properties | Carcinogenesis Dec 2015 | Lenti | TL310083 |
| JPH3 | Junctophilin Proteins Tether a Cav1-RyR2-KCa3.1 Tripartite Complex to Regulate Neuronal Excitability | Cell Rep 2019 | Lenti | TL705996 |
| JPH4 | Junctophilin Proteins Tether a Cav1-RyR2-KCa3.1 Tripartite Complex to Regulate Neuronal Excitability | Cell Rep 2019 | Lenti | TL700489 |
| KAT8 | Chromatin regulation by Histone H4 acetylation at Lysine 16 during cell death and differentiation in the myeloid compartment | Nucleic Acids Res. 2019 | Lenti | TL303060 |
| KCNK2 | Trabecular Meshwork TREK-1 Channels Function as Polymodal Integrators of Pressure and pH | Invest. Ophthalmol. Vis. Sci. 2019 | Lenti | TL312003 |
| KCNQ1 | Suppression-Replacement KCNQ1 Gene Therapy for Type 1 Long QT Syndrome | Circulation 2021 | Lenti | TL303806 |
| KCTD5 | K+ Channel Tetramerization Domain 5 (KCTD5) Protein Regulates Cell Migration, Focal Adhesion Dynamics and Spreading through Modulation of Ca2+ Signaling and Rac1 Activity | Cells 2020 | Lenti | TL303786 |
| KDM3A | Hypoxia-inducible KDM3A addiction in multiple myeloma | Blood Adv 2018 | Lenti | TL303857 |
| KDM4B | Ascorbate and Iron Are Required for the Specification and Long-Term Self-Renewal of Human Skeletal Mesenchymal Stromal Cells | Stem Cell Reports 2020 | Lenti | RC223401L3 |
| KDM4B | Ascorbate and Iron Are Required for the Specification and Long-Term Self-Renewal of Human Skeletal Mesenchymal Stromal Cells | Stem Cell Reports 2020 | Lenti | TL312052 |
| KDM5A | Vitamin C promotes pluripotency of human induced pluripotent stem cells via the histone demethylase JARID1A | Biol. Chem. 2016 | Lenti | TL312057 |
| KDM6A | Contingencies of UTX/KDM6A Action in Urothelial Carcinoma | Cancers (Basel) 2019 | Lenti | RC210861L2 |
| KDM6A | MBD3/NuRD loss participates with KDM6A program to promote DOCK5/8 expression and Rac GTPase activation in human acute myeloid leukemia | FASEB J. 2019 | Lenti | RC210861L4 |
| KDM6A | THE ROLE OF KDM6A/UTX IN BLADDER CANCER: FROM MUTATIONS TO THERAPEUTIC INTERVENTION | thesis Oct 2015 | Lenti | RC210861L2 |
| KDM6B | Epigenetic regulation of TGF-β-induced EMT by JMJD3/KDM6B histone H3K27 demethylase | Oncogenesis 2021 | Lenti | TL320873 |
| KDM6B | Notch-effector CSL promotes squamous cell carcinoma by repressing histone demethylase KDM6B | J. Clin. Invest. 2018 | Lenti | HC141378 |
| KDSR | Sphingolipid dysregulation due to lack of functional KDSR impairs proplatelet formation causing thrombocytopenia | Haematologica 2018 | Lenti | RC201153L3 |
| KEAP1 | Nrf2 and HIF1α converge to arsenic-induced metabolic reprogramming and the formation of the cancer stem-like cells | Theranostics 2020 | Lenti | RC202189L4 |
| KHSRP | KSRP specifies monocytic and granulocytic differentiation through regulating miR-129 biogenesis and RUNX1 expression | Nat Commun 2017 | Lenti | TL311984 |
| KIAA0101 | PCNA-associated factor P15PAF , targeted by FOXM1, predicts poor prognosis in high-grade serous ovarian cancer patients | Int. J. Cancer 2018 | Lenti | RC216104L3 |
| KIF13A | KIF13A mediates the activity-dependent transport of ESCRT-0 proteins in axons | bioRxiv 2020 | Lenti | TL706020 |
| KIF18A | Expression of KIF18A Is Associated with Increased Tumor Stage and Cell Proliferation in Prostate Cancer | Med. Sci. Monit. 2019 | Lenti | TL303697 |
| KIF26B | Upregulation of KIF26B, Cell Migration and Proliferation of Human Ovarian Cancer Cell Lines In Vitro, and Patient Outcomes from Human Bioinformatic Analysis | Med. Sci. Monit. 2018 | Lenti | TL508079 |
| KIF3B | Identification of kinesin family member 3B (KIF3B) as a molecular target for gastric cancer | Kaohsiung J. Med. Sci. 2020 | Lenti | TL311910 |
| KIR2DL5A | KIR2DL5 mutation and loss underlies sporadic dermal neurofibroma pathogenesis and growth | Oncotarget 2017 | Lenti | RC213765L2 |
| KITLG | A juxtacrine/paracrine loop between C-Kit and stem cell factor promotes cancer stem cell survival in epithelial ovarian cancer | Cell Death Dis 2019 | Lenti | RC213540L4 |
| KL | FGF23 ameliorates ischemia-reperfusion induced acute kidney injury via modulation of endothelial progenitor cells: targeting SDF-1/CXCR4 signaling | Cell death & disease 2021 | Lenti | TL303679 |
| KL | Klotho overexpression improves amyloid-β clearance and cognition in the APP/PS1 mouse model of Alzheimer\'s disease | Aging Cell 2020 | Lenti | MR227101L2 |
| KL | Klotho overexpression improves amyloid-β clearance and cognition in the APP/PS1 mouse model of Alzheimer\'s disease | Aging Cell 2020 | Lenti | TL303679 |
| KL | Lentiviral vector–mediated overexpression of Klotho in the brain improves Alzheimer's disease–like pathology and cognitive deficits in mice | Neurobiology of Aging 2019 | Lenti | MR227101L2 |
| KL | Ginsenoside-Rg1 Protects against Renal Fibrosis by Regulating the Klotho/TGF-β1/Smad Signaling Pathway in Rats with Obstructive Nephropathy | Biol. Pharm. Bull. 2018 | Lenti | TL711301 |
| KL | Lentiviral-mediated klotho up-regulation improves aging-related memory deficits and oxidative stress in senescence-accelerated mouse prone-8 mice | Life Sci. 2018 | Lenti | MR227101L2 |
| Kl | Protective Effect of Klotho against Ischemic Brain Injury Is Associated with Inhibition of RIG-I/NF-κB Signaling | Front Pharmacol 2017 | Lenti | MR227101L2 |
| Kl | Protective Effect of Klotho against Ischemic Brain Injury Is Associated with Inhibition of RIG-I/NF-κB Signaling | Front Pharmacol 2017 | Lenti | TL711301 |
| KLB | Klotho Exerts an Emerging Role in Cytokinesis | Genes (Basel) 2020 | Lenti | TL303678 |
| KLF2 | Flow-dependent expression of ectonucleotide tri(di)phosphohydrolase-1 and suppression of atherosclerosis | J. Clin. Invest. Jun 2015 | Lenti | RC210042L1 |
| KLF3 | Epigenetic silencing of Kruppel like factor-3 increases expression of pro-metastatic miR-182 | Cancer Lett. Aug 2015 | Lenti | TL303669 |
| KLF4 | JAK2 inhibition in JAK2V617F-bearing leukemia cells enriches CD34+ leukemic stem cells that are abolished by the telomerase inhibitor GRN163L | Biochem. Biophys. Res. Commun. 2020 | Lenti | TL316853 |
| KLF4 | TFAP2C- and p63-Dependent Networks Sequentially Rearrange Chromatin Landscapes to Drive Human Epidermal Lineage Commitment | Cell Stem Cell 2019 | Lenti | TL316853 |
| KLF4 | Kruppel-like factor4 regulates PRDM1 expression through binding to an autoimmune risk allele | JCI Insight 2017 | Lenti | TL316853 |
| KMT2A | Targeting the MLL complex in castration-resistant prostate cancer | Nat. Med. Apr 2015 | Lenti | TL311462 |
| KMT2B | Targeting the MLL complex in castration-resistant prostate cancer | Nat. Med. Apr 2015 | Lenti | TL315696 |
| KNSTRN | Characterization of SKAP/Kinastrin isoforms - The N-terminus defines tissue specificity and Pontin binding | Hum. Mol. Genet. May 2016 | Lenti | TL306156 |
| KTI12 | Same but different - Molecular comparison of human KTI12 and PSTK | Biochimica et biophysica acta. Molecular cell research 2021 | Lenti | RC204261L3 |
| LAMC2 | Exosomal microRNA‑146a derived from mesenchymal stem cells increases the sensitivity of ovarian cancer cells to docetaxel and taxane via a LAMC2‑mediated PI3K/Akt axis | Int J Mol Med 2020 | Lenti | RC222076L4 |
| LAMC2 | LAMC2 regulated by microRNA-125a-5p accelerates the progression of ovarian cancer via activating p38 MAPK signalling | Life Sci. 2019 | Lenti | RC222076L4 |
| LAMP1 | Hydroxypropyl-beta and -gamma cyclodextrins rescue cholesterol accumulation in Niemann-Pick C1 mutant cell via lysosome-associated membrane protein 1 | Cell Death Dis 2018 | Lenti | TL311795 |
| LARS | PHD1 controls muscle mTORC1 in a hydroxylation-independent manner by stabilizing leucyl tRNA synthetase | Nat Commun 2020 | Lenti | RC221682L3 |
| LDHA | Sirtuin 6 suppresses hypoxia-induced inflammatory response in human osteoblasts via inhibition of reactive oxygen species production and glycolysis-A therapeutic implication in inflammatory bone resorption | Biofactors 2016 | Lenti | TL311769 |
| LDLR | Targeting lipid droplet lysophosphatidylcholine for cisplatin chemotherapy | J. Cell. Mol. Med. 2020 | Lenti | RC200006L2 |
| LDLR | Low-Density Lipoprotein Receptor-Mediated Lipidome-Transcriptome Reprogramming Impulses to Cisplatin Insensitivity | bioRxiv 2018 | Lenti | RC200006L2 |
| LEF1 | Single-cell Analysis Reveals a Preexisting Drug-Resistant Subpopulation in the Luminal Breast Cancer Subtype | Cancer Res. 2019 | Lenti | RC208663L1 |
| LEF1 | BMP and WNT signalling cooperate through LEF1 in the neuronal specification of adult hippocampal neural stem and progenitor cells | Sci Rep 2018 | Lenti | RC225565L2 |
| Lenti Concentrator | Multi-omics analyses reveal that HIV-1 alters CD4+ T cell immunometabolism to fuel virus replication | Nature immunology 2021 | Lenti | TR30026 |
| Lenti Concentrator | EDC3 phosphorylation regulates growth and invasion through controlling P-body formation and dynamics | EMBO reports 2021 | Lenti | TR30025 |
| Lenti Concentrator | Pan-cancer multi-omics analysis and orthogonal experimental assessment of epigenetic driver genes | Genome Res. 2020 | Lenti | TR30025 |
| Lenti Concentrator | Establishment of an induced pluripotent cell line from Taiwan black silkie chick embryonic fibroblasts for replication-incompetent virus production | Sci Rep 2019 | Lenti | TR30025 |
| Lenti Concentrator | Insulin Induces Microtubule Stabilization and Regulates the Microtubule Plus-End Tracking Protein Network in Adipocytes | Mol. Cell Proteomics 2019 | Lenti | TR30025 |
| Lenti Concentrator | The mitochondrial metabolic function of DJ-1 is modulated by 14-3-3β | FASEB J. 2019 | Lenti | TR30025 |
| Lenti Titer Kit | RNA Binding Antagonizes Neurotoxic Phase Transitions of TDP-43 | Neuron 2019 | Lenti | TR30038 |
| Lenti-vpak Lentiviral Packaging Kit | The role of TNFRSF11B in development of osteoarthritic cartilage | Rheumatology (Oxford, England) 2021 | Lenti | TR30037 |
| Lenti-vpak packaging | Genome-wide RNAi Screen identifies PMPCB as a therapeutic vulnerability in EpCAM+ hepatocellular carcinoma | Cancer Res. 2019 | Lenti | TR30037 |
| Lenti-vpak packaging | Oncogenic and osteolytic functions of histone demethylase NO66 in castration-resistant prostate cancer | Oncogene 2019 | Lenti | TR30037 |
| Lenti-vpak packaging | The impact of hepatic HSP72 on insulin signaling | Am. J. Physiol. Endocrinol. Metab. 2018 | Lenti | TR30037 |
| Lenti-vpak packaging | Drug-induced aneuploidy and polyploidy is a mechanism of disease relapse in MYC/BCL2-addicted diffuse large B-cell lymphoma | Oncotarget 2018 | Lenti | TR30037P5 |
| Lenti-vpak packaging | Infants Uniquely Express High Levels of RBM3 and Other Cold-Adaptive Neuroprotectant Proteins in the Human Brain | Dev. Neurosci. 2018 | Lenti | TR30037 |
| Lenti-vpak packaging | Targeting LRH‑1 in hepatoblastoma cell lines causes decreased proliferation | Oncol. Rep. 2018 | Lenti | TR30037 |
| Lenti-vpak packaging | Targeting Interleukin-6 (IL-6) Sensitizes Anti-PD-L1 Treatment in a Colorectal Cancer Preclinical Model | Med. Sci. Monit. 2018 | Lenti | TR30037 |
| Lenti-vpak packaging | Wnt5a/FZD4 Mediates the Mechanical Stretch-Induced Osteogenic Differentiation of Bone Mesenchymal Stem Cells | Cell. Physiol. Biochem. 2018 | Lenti | TR30037 |
| Lenti-vpak packaging | Engineering PD-1-Presenting Platelets for Cancer Immunotherapy | Nano Lett. 2018 | Lenti | TR300037 |
| Lenti-vpak packaging | CADM1 is essential for KSHV-encoded vGPCR-and vFLIP-mediated chronic NF-κB activation | PLoS Pathog. 2018 | Lenti | TR30037 |
| Lenti-vpak packaging | Interleukin-23 promotes the migration and invasion of gastric cancer cells by inducing epithelial-to-mesenchymal transition via the STAT3 pathway | Biochem. Biophys. Res. Commun. 2018 | Lenti | TR30037 |
| Lenti-vpak packaging | The role ofcalgranulin Bgene on the biological behavior of squamous cervical cancer in vitro and in vivo | Cancer Manag Res 2018 | Lenti | TR30037 |
| Lenti-vpak packaging | AGBL2 promotes cancer cell growth through IRGM-regulated autophagy and enhanced Aurora A activity in hepatocellular carcinoma | Cancer Lett.2017 | Lenti | TR30037 |
| Lenti-vpak packaging | Interferon-γ is a master checkpoint regulator of cytokine-induced differentiation | Proc. Natl. Acad. Sci. U.S.A. 2017 | Lenti | TR30037 |
| Lenti-vpak packaging | Whole-transcriptome microarray analysis reveals regulation of Rab4 by RBM5 in neurons | Neuroscience 2017 | Lenti | TR30037P5 |
| Lenti-vpak packaging | MARK4 regulates NLRP3 positioning and inflammasome activation through a microtubule-dependent mechanism | Nat Commun 2017 | Lenti | TR30037 |
| Lenti-vpak packaging | Curcumin inhibits prostate cancer by targeting PGK1 in the FOXD3/miR-143 axis | Cancer Chemother. Pharmacol. 2017 | Lenti | TR30037 |
| Lenti-vpak packaging | A stemness-related ZEB1-MSRB3 axis governs cellular pliancy and breast cancer genome stability | Nat. Med. 2017 | Lenti | TR30037 |
| Lenti-vpak packaging | β-Carotene suppresses osteoclastogenesis and bone resorption by suppressing NF-κB signaling pathway | Life Sci 2017 | Lenti | TR30037 |
| Lenti-vpak packaging | Metabolic Adaptation to Nutritional Stress in Human Colorectal Cancer | Sci Rep 2016 | Lenti | TR30037 |
| Lenti-vpak packaging | Targeting tissue inhibitor of metalloproteinase 1/2 using a shRNA lentiviral system offers a novel treatment strategy against hepatic fibrosis | Int J Clin Exp Med 2016 | Lenti | TR30037 |
| Lenti-vpak packaging | TFAP2C-mediated upregulation of TGFBR1 promotes lung tumorigenesis and epithelial-mesenchymal transition | Exp. Mol. Med. 2016 | Lenti | TR30037 |
| Lenti-vpak packaging | Sphingomyelin-induced inhibition of the plasma membrane calcium ATPase causes neurodegeneration in type A Niemann-Pick disease | Mol. Psychiatry 2016 | Lenti | TR30037 |
| Lenti-vpak packaging | TFAP2C promotes lung tumorigenesis and aggressiveness through miR-183- and miR-33a-mediated cell cycle regulation | Oncogene 2016 | Lenti | TR30037 |
| Lenti-vpak packaging | MiR-122 targets VEGFC in bladder cancer to inhibit tumor growth and angiogenesis | Am J Transl Res 2016 | Lenti | TR30037 |
| Lenti-vpak packaging | Coronin 1B serine 2 phosphorylation by p38a is critical for vascular endothelial growth factor-induced migration of human umbilical vein endothelial cells | Cell. Signal. 2016 | Lenti | TR30037 |
| Lenti-vpak packaging | Expression of RXFP1 is Decreased in Idiopathic Pulmonary Fibrosis: Implications for Relaxin-Based Therapies | Am. J. Respir. Crit. Care Med. Jun 2016 | Lenti | TR30037 |
| Lenti-vpak packaging | Bacteroides fragilis Enterotoxin Upregulates Heme Oxygenase-1 in Intestinal Epithelial Cells via a Mitogen-Activated Protein Kinases- and NF-?B-Dependent Pathway, Leading to Modulation of Apoptosis | Infect. Immun. Jun 2016 | Lenti | TR30037 |
| Lenti-vpak packaging | Targeting carbonic anhydrase IX improves the anti-cancer efficacy of mTOR inhibitors | Oncotarget 2016 | Lenti | TR30037 |
| Lenti-vpak packaging | ß-cell deletion of Nr4a1 and Nr4a3 nuclear receptors impedes mitochondrial respiration and insulin secretion | Am. J. Physiol. Endocrinol. Metab. May 2016 | Lenti | TR30037 |
| Lenti-vpak packaging | Lens regeneration using endogenous stem cells with gain of visual function | Nature Mar 2016 | Lenti | TR30037 |
| Lenti-vpak packaging | Serum Amyloid A3 Secreted by Preosteoclasts Inhibits Parathyroid Hormone-Stimulated cAMP Signaling in Murine Osteoblasts | J. Biol. Chem. Dec 2015 | Lenti | TR30037 |
| Lenti-vpak packaging | Improvement of mTORC1-driven overproduction of apoB-containing triacylglyceride-rich lipoproteins by short-chain fatty acids, 4-phenylbutyric acid and (R)-a-lipoic acid, in human hepatocellular carcinoma cells | Biochim. Biophys. Acta Dec2015 | Lenti | TR30037 |
| Lenti-vpak packaging | Disease-Causing SDHAF1 Mutations Impair Transfer of Fe-S Clusters to SDHB | Cell Metab. Dec 2015 | Lenti | TR30037 |
| Lenti-vpak packaging | THE ROLE OF KDM6A/UTX IN BLADDER CANCER: FROM MUTATIONS TO THERAPEUTIC INTERVENTION | thesis Oct 2015 | Lenti | TR30037 |
| Lenti-vpak packaging | Insulin enhances RANKL-induced osteoclastogenesis via ERK1/2 activation and induction of NFATc1 and Atp6v0d2 | Cell. Signal. Sep 2015 | Lenti | TR30037 |
| Lenti-vpak packaging | SLC9A3R1 stimulates autophagy via BECN1 stabilization in breast cancer cells | Autophagy Jul 2015 | Lenti | TR30037 |
| Lenti-vpak packaging | Tumour-suppressive function of SIRT4 in human colorectal cancer | Br. J. Cancer Jun 2015 | Lenti | TR30037 |
| Lenti-vpak packaging | Flow-dependent expression of ectonucleotide tri(di)phosphohydrolase-1 and suppression of atherosclerosis | J. Clin. Invest. Jun 2015 | Lenti | TR30037 |
| Lenti-vpak packaging | ATTENUATION OF mTORC1-DRIVEN SECRETION OF LIPOPROTEINS ANDTRIACYLGLYCERIDES BY SHORT CHAIN FATTY ACIDS: MECHANISTICINSIGHT INTO THE PATHOGENESIS OF HYPERTRIGLYCERIDEMIA | Thesis Apr 2015 | Lenti | TR30037 |
| Lenti-vpak packaging | Phosphorylation and Inactivation of GSK3ß by Dual-Specificity Tyrosine(Y)-Phosphorylation-Regulated Kinase 1A (Dyrk1A) | J. Biol. Chem. Dec 2014 | Lenti | TR30037 |
| Lenti-vpak packaging kit | Carbonic-anhydrase IX expression is increased in thyroid cancer tissue and represents a potential therapeutic target to eradicate thyroid tumor-initiating cells | Molecular and Cellular Endocrinology 2021 | Lenti | TR30037 |
| Lenti-vpak packaging kit | Phosphorylation dependent mitochondrial translocation of Nr4a3 provokes cardiomyocyte death | Research Square 2021 | Lenti | TR30037 |
| Lenti-vpak packaging kit | FoxA2 and RNA Pol II mediate human islet amyloid polypeptide turnover in ER-stressed pancreatic β-cells | The Biochemical journal 2021 | Lenti | TR30037 |
| Lenti-vpak packaging kit | Ectopic CD137 expression by rhabdomyosarcoma provides selection advantages but allows immunotherapeutic targeting | OncoImmunology 2021 | Lenti | TR30037 |
| Lenti-vpak packaging kit | SP1-induced long non-coding RNA SNHG6 facilitates the carcinogenesis of chondrosarcoma through inhibiting KLF6 by recruiting EZH2 | Cell death & disease 2021 | Lenti | TR30037 |
| Lenti-vpak packaging kit | Development of Cell-based High Throughput Luminescence Assay for Drug Discovery in Inhibiting OCT4 and DNA-PKcs Interaction | Authorea 2020 | Lenti | TR30037 |
| Lenti-vpak packaging kit | The Transcription Factor p63 is a Direct Effector of IL-4/IL-13 Mediated Repression of Keratinocyte Differentiation | J Invest Dermatol 2020 | Lenti | TR30037 |
| Lenti-vpak packaging kit | Sirt2 Inhibition Enhances Metabolic Fitness and Effector Functions of Tumor-Reactive T Cells | Cell Metab. 2020 | Lenti | TR30037 |
| Lenti-vpak packaging kit | GULP1 regulates the NRF2-KEAP1 signaling axis in urothelial carcinoma | Sci Signal 2020 | Lenti | TR30037 |
| Lenti-vpak packaging kit | Ovarian Cancer Cells Direct Monocyte Differentiation Through a Non-canonical Pathway | Research Square 2020 | Lenti | TR30037 |
| Lenti-vpak packaging kit | Clinical significance and functional role of transmembrane protein 47 (TMEM47) in chemoresistance of hepatocellular carcinoma | Int J Oncol 2020 | Lenti | TR30037 |
| Lenti-vpak packaging kit | Ovarian Cells Have Increased Proliferation in Response to Heparin-Binding Epidermal Growth Factor as Collagen Density Increases | Tissue Eng Part A 2020 | Lenti | TR300037 |
| Lenti-vpak packaging kit | Formononetin inhibits tumor growth by suppression of EGFR-Akt-Mcl-1 axis in non-small cell lung cancer | J. Exp. Clin. Cancer Res. 2020 | Lenti | TR30037 |
| Lenti-vpak packaging kit | Development of a laboratory scalable process for enhancing lentivirus production by transient transfection of HEK293 adherent cultures | Gene Ther. 2020 | Lenti | TR30037 |
| Lenti-vpak packaging kit | Decorin knockdown affects the gene expression profile of adhesion, growth and extracellular matrix metabolism in C-28/I2 chondrocytes | PLoS ONE 2020 | Lenti | TR30037 |
| Lenti-vpak packaging kit | Alpha-Catulin, a New Player in a Rho Dependent Apical Constriction That Contributes to the Mouse Neural Tube Closure | Front. Cell Dev. Biol. 2020 | Lenti | TR30037 |
| Lenti-vpak packaging kit | Deguelin suppresses non-small cell lung cancer by inhibiting EGFR signaling and promoting GSK3β/FBW7-mediated Mcl-1 destabilization | Cell Death Dis 2020 | Lenti | TR30037 |
| Lenti-vpak packaging kit | A rare codon-based translational program of cell proliferation | Genome Biol. 2020 | Lenti | TR30037 |
| Lenti-vpak packaging kit | The deubiquitinase OTUB1 augments NF-κB-dependent immune responses in dendritic cells in infection and inflammation by stabilizing UBC13 | Cell. Mol. Immunol. 2020 | Lenti | TR30037 |
| Lenti-vpak packaging kit | Knockdown of P3H4 inhibits proliferation and invasion of bladder cancer | Aging (Albany NY) 2020 | Lenti | TR30037 |
| Lenti-vpak packaging kit | Endocytosis of very low-density lipoproteins: an unexpected mechanism for lipid acquisition by breast cancer cells | J. Lipid Res. 2019 | Lenti | TR30037 |
| Lenti-vpak packaging kit | Enhanced hexosamine metabolism drives metabolic and signaling networks involving hyaluronan production and O-GlcNAcylation to exacerbate breast cancer | Cell Death Dis 2019 | Lenti | TR30037 |
| Lenti-vpak packaging kit | DCLK1 INTEGRATES INDUCTION OF TRIB3, EMT, DRUG RESISTANCE, and POOR PROGNOSIS IN COLORECTAL CANCER | Carcinogenesis 2019 | Lenti | TR30037 |
| Lenti-vpak packaging kit | Fenretinide via NOXA induction, enhanced activity of the BCL-2 inhibitor venetoclax in high BCL-2-expressing neuroblastoma preclinical models | Mol. Cancer Ther. 2019 | Lenti | TR30037 |
| Lenti-vpak packaging kit | The chromatin remodeler SMARCD3 regulates cell cycle progression and its expression predicts survival outcome in ER+ breast cancer | bioRxiv 2019 | Lenti | TR30037 |
| Lenti-vpak packaging kit | Endocytosis of very low-density lipoprotein particles: an unexpected mechanism for lipid acquisition by breast cancer cells | bioRxiv 2019 | Lenti | TR30037 |
| Lenti-vpak packaging kit | TGFβ-induced degradation of TRAF3 in mesenchymal progenitor cells causes age-related osteoporosis | Nat Commun 2019 | Lenti | TR30037 |
| Lenti-vpak packaging kit | Subregional differences in astrocytes underlie selective neurodegeneration or protection in Parkinson's disease models in culture | Glia 2019 | Lenti | TR30037 |
| Lenti-vpak packaging kit | Network approach identifies Pacer as an autophagy protein involved in ALS pathogenesis | Mol Neurodegener 2019 | Lenti | TR30037 |
| Lenti-vpak packaging kit | Thioredoxin system as a gatekeeper in caspase-6 activation and nuclear lamina integrity: Implications for Alzheimer's disease | Free Radic. Biol. Med. 2019 | Lenti | TR30037 |
| Lenti-vpak packaging kit | EGFR signaling confers resistance to BET inhibition in hepatocellular carcinoma through stabilizing oncogenic MYC | J. Exp. Clin. Cancer Res. 2019 | Lenti | TR30037 |
| Lenti-vpak packaging kit | Overexpression of CD59 inhibits apoptosis of T-acute lymphoblastic leukemia via AKT/Notch1 signaling pathway | Cancer Cell Int. 2019 | Lenti | TR30037 |
| Lenti-vpak packaging kit | Activating transcription factor 3 enhances chemosensitivity of dichloroacetic acid via p53 pathway in cervical squamous epithelial cancer cells | Tropical Journal of Pharmaceutical Research 2018 | Lenti | TR30037 |
| LGALS1 | Galectin-1 suppression delineates a new strategy to inhibit myeloma-induced angiogenesis and tumoral growth in vivo | Leukemia 2016 | Lenti | TL311756 |
| LGR5 | Lgr5 maintains stemness and regulates cell property in nasopharyngeal carcinoma through Wnt/β-catenin signaling pathway | Stem Cell Res 2020 | Lenti | TL311747 |
| LIX1 | LIX1 regulates YAP activity and controls gastrointestinal cancer cell plasticity | J. Cell. Mol. Med. 2020 | Lenti | TL303518 |
| LMBRD1 | LMBD1 protein participates in cell mitosis by regulating microtubule assembly | The Biochemical journal 2021 | Lenti | TL303512 |
| LPA | Effects of LPA1 and LPA6 on the regulation of colony formation activity in colon cancer cells treated with anticancer drugs | J. Recept. Signal Transduct. Res. 2018 | Lenti | TL311698 |
| LPA | Involvement of LPA receptor-5 in the enhancement of cell motile activity by phorbol ester and anticancer drug treatments in melanoma A375 cells | Biochem. Biophys. Res. Commun. 2018 | Lenti | TL311698 |
| LPCAT3 | Caspase-independent hepatocyte death: A result of the decrease of lysophosphatidylcholine acyltransferase 3 in non-alcoholic steatohepatitis | J. Gastroenterol. Hepatol. 2018 | Lenti | RC209485L2 |
| LPL | Endocytosis of very low-density lipoprotein particles: an unexpected mechanism for lipid acquisition by breast cancer cells | bioRxiv 2019 | Lenti | TL311692 |
| Lrp6 | Oncogenic KRAS signalling promotes the Wnt/ß-catenin pathway through LRP6 in colorectal cancer | Oncogene Dec 2014 | Lenti | TL706439 |
| LY6C | Ly6C+ Inflammatory Monocyte Differentiation Partially Mediates Hyperhomocysteinemia-Induced Vascular Dysfunction in Type 2 Diabetic db/db Mice | Arterioscler. Thromb. Vasc. Biol. 2019 | Lenti | TL513893 |
| MACC1 | MACC1 regulates clathrin-mediated endocytosis and receptor recycling of transferrin receptor and EGFR in colorectal cancer | Cellular and molecular life sciences : CMLS 2021 | Lenti | RC224774L2 |
| MACC1 | Saffron Crudes and Compounds Restrict MACC1-Dependent Cell Proliferation and Migration of Colorectal Cancer Cells | Cells 2020 | Lenti | RC224774L2 |
| MAF | Unraveling the transcriptional determinants of Liver Sinusoidal Endothelial Cell specialization | Am. J. Physiol. Gastrointest. Liver Physiol. 2020 | Lenti | RC209247L2 |
| MAGEA12 | Overexpression and Implications of Melanoma-associated Antigen A12 in Pathogenesis of Human Cutaneous Squamous Cell Carcinoma | Anticancer Res. 2019 | Lenti | TL311615V |
| MAGI2 | Disruption of MAGI2-RapGEF2-Rap1 signaling contributes to podocyte dysfunction in congenital nephrotic syndrome caused by mutations in MAGI2 | Kidney International 2019 | Lenti | TL311600 |
| MAMLD1 | Attenuation of MAMLD1 Expression Suppresses the Growth and Migratory Properties of Gonadotroph Pituitary Adenomas | Pathol. Oncol. Res. 2019 | Lenti | TL313623 |
| MAN1A1 | Reduced mannosidase MAN1A1 expression leads to aberrant N-glycosylation and impaired survival in breast cancer | Br. J. Cancer 2018 | Lenti | TL311595 |
| MAP1LC3B | Curcumin induces apoptotic cell death and protective autophagy by inhibiting AKT/mTOR/p70S6K pathway in human ovarian cancer cells | Arch. Gynecol. Obstet. 2019 | Lenti | RC207356L3 |
| MAP2K1 | MiR-16 regulates the pro-tumorigenic potential of lung fibroblasts through the inhibition of HGF production in an FGFR-1- and MEK1-dependent manner | J Hematol Oncol 2018 | Lenti | RC218460L1 |
| MAP3K12 | Intrathecal Injection of Dual Zipper Kinase shRNA Alleviating the Neuropathic Pain in a Chronic Constrictive Nerve Injury Model | Int J Mol Sci 2018 | Lenti | TL709656 |
| MAPRE1 | EB1- and EB2-dependent anterograde trafficking of TRPM4 regulates focal adhesion turnover and cell invasion | FASEB J. 2019 | Lenti | TL316980 |
| MAPT | Increased Tau Expression Correlates With IDH Mutation in Infiltrating Gliomas and Impairs Cell Migration | J. Neuropathol. Exp. Neurol. 2020 | Lenti | RC217773L2V |
| MAPT | miR-186 regulates chemo-sensitivity to paclitaxel via targeting MAPT in non-small cell lung cancer (NSCLC) | Molecular BioSystems 2016 | Lenti | RC216166L1 |
| MARK4 | MARK4 regulates NLRP3 positioning and inflammasome activation through a microtubule-dependent mechanism | Nat Commun 2017 | Lenti | TL303343 |
| MAVS | Pervasive H3K27 Acetylation Leads to ERV Expression and a Therapeutic Vulnerability in H3K27M Gliomas | Cancer Cell 2019 | Lenti | TL307181 |
| MBNL1 | Muscleblind acts as a modifier of FUS toxicity by modulating stress granule dynamics and SMN localization | Nat Commun 2019 | Lenti | TL303325 |
| MCAM | CD146 interacts with galectin-3 to mediate endothelial cell migration | FEBS Lett. 2018 | Lenti | TL311550 |
| MCL1 | MicroRNA-451 sensitizes lung cancer cells to cisplatin through regulation of Mcl-1 | Mol. Cell. Biochem. 2016 | Lenti | RC231044L2 |
| Mcm4 | Replication stress is a potent driver of functional decline in ageing haematopoietic stem cells | Nature July 2014 | Lenti | TL514127 |
| Mcm6 | Replication stress is a potent driver of functional decline in ageing haematopoietic stem cells | Nature July 2014 | Lenti | TL510769 |
| MDC1 | BRCT-domain protein BRIT1 influences class switch recombination | Proc. Natl. Acad. Sci. U.S.A. 2017 | Lenti | TL517490 |
| MDM2 | MDM2 derived from dedifferentiated liposarcoma extracellular vesicles induces MMP2 production from preadipocytes | Cancer Res. 2019 | Lenti | TL311529 |
| MDM2 | p16 Controls p53 Protein Expression through miR-dependent Destabilization of MDM2 | Mol. Cancer Res. 2018 | Lenti | TL311529 |
| MDM2 | p53 participates in the protective effects of ischemic post-conditioning against OGD-reperfusion injury in primary cultured spinal cord neurons | Neurosci. Lett 2016 | Lenti | TL311529 |
| MECP2 | MECP2 Increases the Pro-Inflammatory Response of Microglial Cells and Phosphorylation at Serine 423 Regulates Neuronal Gene Expression upon Neuroinflammation | Cells 2021 | Lenti | RC202382L1 |
| MED19 | MED19 alters AR occupancy and gene expression in prostate cancer cells, driving MAOA expression and growth under low androgen | bioRxiv 2019 | Lenti | RC206806L1 |
| MEF2C | Myocyte-specific enhancer factor 2c triggers transdifferentiation of adipose tissue-derived stromal cells into spontaneously beating cardiomyocyte-like cells | Scientific reports 2021 | Lenti | MR226865L4V |
| MEG3 | Long Noncoding RNA (lncRNA) Maternally Expressed Gene 3 (MEG3) Participates in Chronic Obstructive Pulmonary Disease through Regulating Human Pulmonary Microvascular Endothelial Cell Apoptosis | Med Sci Monit 2020 | Lenti | TL320132 |
| MEG3 | Mechanism associated with aberrant lncRNA MEG3 expression in gestational diabetes mellitus | Exp Ther Med 2019 | Lenti | TL320132 |
| MEG3 | Skp2 regulates non-small cell lung cancer cell growth by Meg3 and miR-3163 | Tumour Biol. Oct 2015 | Lenti | TL320132 |
| MEIS2 | Unraveling the transcriptional determinants of Liver Sinusoidal Endothelial Cell specialization | Am. J. Physiol. Gastrointest. Liver Physiol. 2020 | Lenti | RC222807L2 |
| MET | Role of HGF/c-Met in the treatment of colorectal cancer with liver metastasis | J. Biochem. Mol. Toxicol. 2019 | Lenti | TL320418 |
| METTL3 | Kaposi's Sarcoma-Associated Herpesvirus Utilizes and Manipulates RNA N6-Adenosine Methylation To Promote Lytic Replication | J. Virol. 2017 | Lenti | TL303281 |
| MEX3A | The RNA-Binding Ubiquitin Ligase MEX3A Affects Glioblastoma Tumorigenesis by Inducing Ubiquitylation and Degradation of RIG-I | Cancers (Basel) 2020 | Lenti | TL308061 |
| MFN2 | Mul1 restrains Parkin-mediated mitophagy in mature neurons by maintaining ER-mitochondrial contacts | Nat Commun 2019 | Lenti | TL506067 |
| MGA | Genomic and Transcriptomic Characterization of Natural Killer T Cell Lymphoma | Cancer Cell 2020 | Lenti | TL317004 |
| MGEA5 | O-GlcNAcase targets pyruvate kinase M2 to regulate tumor growth | Oncogene 2019 | Lenti | TL315637 |
| MGRN1 | E3 ligase mahogunin (MGRN1) influences amyloid precursor protein maturation and secretion | Oncotarget 2017 | Lenti | TL303267 |
| MGRN1 | Aging Triggers Cytoplasmic Depletion and Nuclear Translocation of the E3 Ligase Mahogunin: A Function for Ubiquitin in Neuronal Survival | Mol. Cell 2017 | Lenti | TL702100 |
| MLH1 | MicroRNA-148b regulates radioresistance in non-small lung cancer cells via regulation of MutL homolog 1 | Biosci. Rep. Jan 2016 | Lenti | TL320419 |
| MLH1 | MicroRNA-148b regulates radioresistance in non-small lung cancer cells via regulation of MutL homolog 1 | Biosci. Rep. Jan 2016 | Lenti | RC201607L1 |
| MLLT4 | Concomitant binding of Afadin to LGN and F-actin directs planar spindle orientation | Nat. Struct. Mol. Biol. Feb 2016 | Lenti | TL311457 |
| MLX | The glucose-sensing transcription factor MLX promotes myogenesis via myokine signaling | Genes Dev. Dec 2015 | Lenti | TL513600 |
| MMP-7 | Sphingosine-1-phosphate induced epithelial-mesenchymal transition of hepatocellular carcinoma via an MMP-7/ syndecan-1/TGF-ß autocrine loop | Oncotarget 2016 | Lenti | TL311438 |
| MMP9 | MicroRNA-3713 regulates bladder cell invasion via MMP9 | Sci Rep 2016 | Lenti | TL311436 |
| MNAT1 | MAT1 facilitates the lung metastasis of osteosarcoma through upregulation of AKT1 expression | Life Sci. 2019 | Lenti | TL311433 |
| MNX1 | MNX1 is oncogenically upregulated in African-American prostate cancer | Cancer Res. 2016 | Lenti | TL319509 |
| MPV17 | The mitochondrial inner membrane protein MPV17 prevents uracil accumulation in mitochondrial DNA | J. Biol. Chem. 2018 | Lenti | TL316619 |
| MSLN | Mesothelin promotes epithelial-to-mesenchymal transition and tumorigenicity of human lung cancer and mesothelioma cells | Mol. Cancer 2017 | Lenti | TL311377 |
| MSLN | Role of mesothelin in carbon nanotube-induced carcinogenic transformation of human bronchial epithelial cells | Am. J. Physiol. Lung Cell Mol. Physiol. 2016 | Lenti | TL311377 |
| MSRB3 | A stemness-related ZEB1-MSRB3 axis governs cellular pliancy and breast cancer genome stability | Nat. Med. 2017 | Lenti | TL315359 |
| MTFP1 | Mitochondrial protein 18 is a positive apoptotic regulator in cardiomyocytes under oxidative stress | Clin. Sci. 2019 | Lenti | TL307024 |
| MUCL1 | HER2 drives Mucin-like 1 to control proliferation in breast cancer cells | Oncogene Jan 2016 | Lenti | RC213754L1 |
| MX2 | MX2 is an interferon-induced inhibitor of HIV-1 infection | Nature. 2013 Oct 24;502(7472):563-6. | Lenti | TL311334 |
| MYB | Regulation of the Flt3 Gene in Haematopoietic Stem and Early Progenitor Cells | PLoS ONE Sep 2015 | Lenti | TL311329 |
| MYC | PD-L1 is overexpressed on breast cancer stem cells through notch3/mTOR axis | OncoImmunology 2020 | Lenti | TL311323V |
| MYC | A Potent and Selective Small-Molecule Degrader of STAT3 Achieves Complete Tumor Regression In Vivo | Cancer Cell 2019 | Lenti | RC201611L1V |
| MYC | A Potent and Selective Small-Molecule Degrader of STAT3 Achieves Complete Tumor Regression In Vivo | Cancer Cell 2019 | Lenti | RC201611L3V |
| MYC | MYC Amplification as a Potential Mechanism of Primary Resistance to Crizotinib in ALK-Rearranged Non-Small Cell Lung Cancer: A Brief Report | Transl Oncol 2018 | Lenti | RC201611L4 |
| MYCN | A conserved HH-Gli1-Mycn network regulates heart regeneration from newt to human | Nat Commun 2018 | Lenti | MR207382L2 |
| MYH10 | Cytoplasmic mislocalization of RNA splicing factors and aberrant neuronal gene splicing in TDP-43 transgenic pig brain | Mol Neurodegener Sep 2015 | Lenti | TL711338 |
| MYO1F | MYO1F Regulates IgE and MRGPRX2-Dependent Mast Cell Exocytosis | Journal of immunology (Baltimore, Md. : 1950) 2021 | Lenti | TL311296 |
| MYO5A | Actin and Myosin-dependent localization of mRNA to dendrites | PLoS ONE Mar 2014 | Lenti | TL311295 |
| NANOG | Low-Level Nanog Expression in the Regulation of Quiescent Endothelium | Arterioscler. Thromb. Vasc. Biol. 2020 | Lenti | TL303039 |
| NAV3 | MiR-21 promoted proliferation and migration in hepatocellular carcinoma through negative regulation of Navigator-3 | Biochem. Biophys. Res. Commun. Jul 2015 | Lenti | TL311261 |
| NDP | Norrin mediates tumor-promoting and -suppressive effects in glioblastoma via Notch and WNT | J. Clin. Invest. 2020 | Lenti | RC206555L2 |
| NDP | Norrin mediates tumor-promoting and -suppressive effects in glioblastoma via Notch and WNT | J. Clin. Invest. 2020 | Lenti | TL316631 |
| NEBL | LIM-Nebulette Reinforces Podocyte Structural Integrity by Linking Actin and Vimentin Filaments | J. Am. Soc. Nephrol. 2020 | Lenti | TL302993 |
| NEFH | A pan-cancer transcriptome analysis of exitron splicing identifies novel cancer driver genes and neoepitopes | Molecular cell 2021 | Lenti | RC213487L3 |
| Negative Control | Breast cancer-associated skeletal muscle mitochondrial dysfunction and lipid accumulation is reversed by PPARG | BioRxiv 2020 | Lenti | PS100093V |
| Negative Control | TRIM37 is highly expressed during mitosis in CHON-002 chondrocytes cell line and is regulated by miR-223 | Bone 2020 | Lenti | TR30021V |
| Negative Control | ABCA1/ABCB1 Ratio Determines Chemo- and Immune-Sensitivity in Human Osteosarcoma | Cells 2020 | Lenti | TR30021V |
| Negative Control | Alpha-Catulin, a New Player in a Rho Dependent Apical Constriction That Contributes to the Mouse Neural Tube Closure | Front. Cell Dev. Biol. 2020 | Lenti | TR30021 |
| Negative Control | Rational cotargeting of HDAC6 and BET proteins yields synergistic antimyeloma activity | Blood Adv 2019 | Lenti | PS100093V |
| Negative Control | Mouse genome-wide association studies and systems genetics uncover the genetic architecture associated with hepatic pharmacokinetic and pharmacodynamic properties of a constrained ethyl antisense oligonucleotide targeting Malat1 | PLoS Genet. 2018 | Lenti | TR30021V |
| Negative Control | Differential expression of secreted factors SOSTDC1 and ADAMTS8 cause pro-fibrotic changes in linear morphoea fibroblasts | Br. J. Dermatol. 2018 | Lenti | PS100093V |
| Negative Control | Multi-level Proteomics Identifies CT45 as a Chemosensitivity Mediator and Immunotherapy Target in Ovarian Cancer | Cell 2018 | Lenti | TR30021 |
| Negative Control | Down-regulation of 14-3-3 zeta sensitizes human glioblastoma cells to apoptosis induction | Apoptosis 2018 | Lenti | TR30021V |
| NEK7 | EK7 Regulates NLRP3 Inflammasome Activation and Neuroinflammation Post-traumatic Brain Injury | Front Mol Neurosci 2019 | Lenti | TL515241 |
| NELF | RNAP II processivity is a limiting step for HIV-1 transcription independent of orientation to and activity of endogenous neighboring promoters | Virology Sep 2015 | Lenti | TL317072 |
| NELFE | Oncogenic Activation of the RNA Binding Protein NELFE and MYC Signaling in Hepatocellular Carcinoma | Cancer Cell 2017 | Lenti | RC208658L2 |
| NEUROD1 | Developmental alterations in Huntington's disease neural cells and pharmacological rescue in cells and mice | Nat. Neurosci 2017 | Lenti | TL311201 |
| NEUROD1 | Rapid neurogenesis through transcriptional activation in human stem cells | Mol. Syst. Biol. Nov 2014 | Lenti | TL311201 |
| NF1 | Pathogenic mutations in neurofibromin identifies a leucine-rich domain regulating glioma cell invasiveness | Oncogene 2019 | Lenti | TL509076 |
| NFATC2 | NFATC2 Modulates Radiation Sensitivity in Dermal Fibroblasts From Patients With Severe Side Effects of Radiotherapy | Frontiers in oncology 2020 | Lenti | TL311198 |
| NFE2L2 | c-MYC-directed NRF2 drives malignant progression of head and neck cancer via glucose-6-phosphate dehydrogenase and transketolase activation | Theranostics 2021 | Lenti | TL311194 |
| NFE2L2 | NRF2 regulates core and stabilizing circadian clock loops, coupling redox and timekeeping inMus musculus | Elife 2018 | Lenti | MR226717L1 |
| NFE2L2 | Nrf2 deficiency exacerbates ochratoxin A-induced toxicity in vitro and in vivo | Toxicology 2017 | Lenti | TL311194 |
| NGB | Prodromal Alzheimer\'s Disease: Constitutive Upregulation of Neuroglobin Prevents the Initiation of Alzheimer\'s Pathology | Frontiers in neuroscience 2020 | Lenti | TL503454 |
| NGFR | Polarized cells display asymmetric release of extracellular vesicles | Traffic (Copenhagen, Denmark) 2020 | Lenti | RC207966L2 |
| NGFR | Effects of p75 neurotrophin receptor on regulating hypoxia-induced angiogenic factors in retinal pigment epithelial cells | Mol. Cell. Biochem. Sep 2014 | Lenti | TL311178 |
| NLGN2 | Synaptic deficits in iPSC-derived cortical interneurons in schizophrenia are mediated by NLGN2 and rescued by N-acetylcysteine | Transl Psychiatry 2019 | Lenti | TL302944V |
| NMU | The YAP1-NMU Axis Is Associated with Pancreatic Cancer Progression and Poor Outcome: Identification of a Novel Diagnostic Biomarker and Therapeutic Target | Cancers (Basel) 2019 | Lenti | TL311154 |
| NNAT | Neuronatin is a modifier of estrogen receptor-positive breast cancer incidence and outcome | Breast Cancer Res. Treat. 2019 | Lenti | RC200328L3 |
| NOG | Noggin rescues age-related stem cell loss in the brain of senescent mice with neurodegenerative pathology | Proc. Natl. Acad. Sci. U.S.A. 2018 | Lenti | MR225276L2V |
| NOP2 | A novel AHI-1-BCR-ABL-DNM2 complex regulates leukemic properties of primitive CML cells through enhanced cellular endocytosis and ROS-mediated autophagy | Leukemia 2017 | Lenti | TL311150 |
| NOS2 | TNF-α/IL-1β-licensed mesenchymal stromal cells promote corneal allograft survival via myeloid cell-mediated induction of Foxp3+ regulatory T cells in the lung | FASEB J. 2019 | Lenti | TL709254 |
| NOS2 | Linking of mPGES-1 and iNOS activates stem-like phenotype in EGFR-driven epithelial tumor cells | Nitric Oxide 2017 | Lenti | RC211819L1 |
| NOVA2 | Neuronal Inactivity Co-opts LTP Machinery to Drive Potassium Channel Splicing and Homeostatic Spike Widening | Cell 2020 | Lenti | RC216200L1 |
| NOVA2 | Neuronal Inactivity Co-opts LTP Machinery to Drive Potassium Channel Splicing and Homeostatic Spike Widening | Cell 2020 | Lenti | RC216200L2 |
| NOVA2 | Neuronal Inactivity Co-opts LTP Machinery to Drive Potassium Channel Splicing and Homeostatic Spike Widening | Cell 2020 | Lenti | TL508674 |
| NOX4 | Cooperative Blockade of CK2 and ATM Kinases Drives Apoptosis in VHL-Deficient Renal Carcinoma Cells through ROS Overproduction | Cancers 2021 | Lenti | TL302911 |
| NOX4 | Nox4 regulates InsP 3 receptor‐dependent Ca 2+ release into mitochondria to promote cell survival | EMBO J 2020 | Lenti | TL302911V |
| NOXO1 | NADPH oxidase subunit NOXO1 is a target for emphysema treatment in COPD | Nat Metab 2020 | Lenti | MR205276L1 |
| NPC1 | NPC1 enables cholesterol mobilization during long-term potentiation that can be restored in Niemann-Pick disease type C by CYP46A1 activation | EMBO Rep. 2019 | Lenti | TL311127 |
| NR2F2 | Defining human cardiac transcription factor hierarchies using integrated single-cell heterogeneity analysis | Nat Commun 2018 | Lenti | RC206753L2 |
| NR3C1 | ICBP90 Regulates MIF Expression, Glucocorticoid Sensitivity, and Apoptosis at the , MIF Immune Susceptibility Locus | Arthritis & rheumatology (Hoboken, N.J.) 2021 | Lenti | TL320374 |
| nr3c1 | Glucocorticoid receptor beta increases migration of human bladder cancer cells | Oncotarget 2016 | Lenti | TL320374 |
| NR4A1 | RARβ acts as both an upstream regulator and downstream effector of miR-22, which epigenetically regulates NUR77 to induce apoptosis of colon cancer cells | FASEB J. 2018 | Lenti | TL320381 |
| Nr4a1 | ß-cell deletion of Nr4a1 and Nr4a3 nuclear receptors impedes mitochondrial respiration and insulin secretion | Am. J. Physiol. Endocrinol. Metab. May 2016 | Lenti | TL711049 |
| NR4A2 | NURR1 and ERR1 Modulate the Expression of Genes of a DRD2 Coexpression Network Enriched for Schizophrenia Risk | J. Neurosci. 2020 | Lenti | MR226280L1 |
| NR4A2 | NURR1 and ERR1 Modulate the Expression of Genes of a DRD2 Coexpression Network Enriched for Schizophrenia Risk | J. Neurosci. 2020 | Lenti | TL501521 |
| Nrf2 | Role of KEAP1/NRF2 and TP53 Mutations in Lung Squamous Cell Carcinoma Development and Radiation Resistance | Cancer Discov 2016 | Lenti | TL515053 |
| NTRK2 | Ovarian BDNF promotes survival, migration, and attachment of tumor precursors originated from p53 mutant fallopian tube epithelial cells | Oncogenesis 2020 | Lenti | TL320436V |
| NUMA1 | Concomitant binding of Afadin to LGN and F-actin directs planar spindle orientation | Nat. Struct. Mol. Biol. Feb 2016 | Lenti | TL311065 |
| Nur77 | Bile Acids Regulate Nuclear Receptor (Nur77) Expression and Intracellular Location to Control Proliferation and Apoptosis | Mol. Cancer Res. Sep 2014 | Lenti | TL711049 |
| OCIAD2 | OCIAD2 suppressed tumor growth and invasion via AKT pathway in Hepatocelluar carcinoma | Carcinogenesis 2017 | Lenti | TL311040 |
| OCLN | Occludin deficiency promotes ethanol-induced disruption of colonic epithelial junctions, gut barrier dysfunction and liver damage in mice | Biochim. Biophys. Acta Dec 2015 | Lenti | TL311039 |
| OGT | O-GlcNAcylation Enhances NUSAP1 Stability and Promotes Bladder Cancer Aggressiveness | OncoTargets and therapy 2021 | Lenti | TL302811 |
| OGT | The essential role of YAP O-GlcNAcylation in high-glucose-stimulated liver tumorigenesis | Nat Commun 2017 | Lenti | RC224481L1 |
| Ogt | Reciprocal regulation between O-GlcNAcylation and tribbles pseudokinase 2 (TRIB2) maintains transformative phenotypes in liver cancer cells | Cell. Signal. 2016 | Lenti | MR211521L1 |
| One-Wash Lentivirus Titer Kit | LncRNA Ctcflos orchestrates transcription and alternative splicing in thermogenic adipogenesis | EMBO reports 2021 | Lenti | TR30038 |
| One-Wash Lentivirus Titer Kit | Glutamate receptor ionotropic, kainate 1 serves as a novel tumor suppressor of colorectal carcinoma and predicts clinical prognosis | Exp Ther Med 2020 | Lenti | TR30038 |
| ONECUT2 | ONECUT2 is a driver of neuroendocrine prostate cancer | Nat Commun 2019 | Lenti | RC211951L3 |
| ONECUT2 | ONECUT2 Is a Targetable Master Regulator of Lethal Prostate Cancer That Suppresses the Androgen Axis | SSRN 2018 | Lenti | RC211951L1 |
| OPN1LW | Opsin 3-Gαs Promotes Airway Smooth Muscle Relaxation Modulated by G Protein Receptor Kinase 2 | Am J Respir Cell Mol Biol 2020 | Lenti | RC224868L4V |
| ORAI3 | Arachidonic acid-regulated calcium signaling in T cells from patients with rheumatoid arthritis promotes synovial inflammation | Nature communications 2021 | Lenti | RC202325L1 |
| ORAI3 | Arachidonic acid-regulated calcium signaling in T cells from patients with rheumatoid arthritis promotes synovial inflammation | Nature communications 2021 | Lenti | TL307587 |
| P2RY14 | UDP-glucose, a cellular danger signal, and nucleotide receptor P2Y14 enhance the invasion of human extravillous trophoblast cells | Placenta 2020 | Lenti | TL310644V |
| P2RY2 | P2Y2 Nucleotide Receptor Prompts Human Cardiac Progenitor Cell Activation by Modulating Hippo Signaling | Circ. Res. 2017 | Lenti | RC223931L2 |
| P2RY2 | P2Y2 Nucleotide Receptor Prompts Human Cardiac Progenitor Cell Activation by Modulating Hippo Signaling | Circ. Res. 2017 | Lenti | TL302717 |
| PA2G4 | ErbB3-binding protein 1 (EBP1) represses HNF4α-mediated transcription and insulin secretion in pancreatic β-cells | Journal of Biological Chemistry 2019 | Lenti | TL310638 |
| PADI4 | Colorectal cancer liver metastatic growth depends on PAD4-driven citrullination of the extracellular matrix | Nat Commun 2018 | Lenti | TL310630 |
| PARP1 | Transcriptional Regulation of CCL2 by PARP1 Is a Driver for Invasiveness in Breast Cancer | Cancers (Basel) 2020 | Lenti | TL315488V |
| PARP1 | Epstein-Barr Virus Oncoprotein LMP1 Mediates Epigenetic Changes in Host Gene Expression through PARP1 | J. Virol. 2016 | Lenti | TL709663 |
| PBK | PDZ-Binding Kinase-Dependent Transcriptional Regulation of CCNB2 Promotes Tumorigenesis and Radio-Resistance in Glioblastoma | Transl Oncol 2019 | Lenti | RC203295L2V |
| PBRM1 | Pbrm1 Steers Mesenchymal Stromal Cell Osteolineage Differentiation by Integrating PBAF-Dependent Chromatin Remodeling and BMP/TGF-β Signaling | Cell Rep 2020 | Lenti | TL517996 |
| pCas-Guide | Gut-licensed IFNγ+ NK cells drive LAMP1+TRAIL+ anti-inflammatory astrocytes | Nature 2021 | Lenti | GE100003 |
| PCDH15 | Origins and Proliferative States of Human Oligodendrocyte Precursor Cells | Cell 2020 | Lenti | TL302649V |
| PCDH17 | Loss of protocadherin-17 (PCDH-17) promotes metastasis and invasion through hyperactivation of EGFR/MEK/ERK signaling pathway in hepatocellular carcinoma | Tumour Biol. Sep 2015 | Lenti | TL310584V |
| PCDH17 | Loss of protocadherin-17 (PCDH-17) promotes metastasis and invasion through hyperactivation of EGFR/MEK/ERK signaling pathway in hepatocellular carcinoma | Tumour Biol. Sep 2015 | Lenti | RC206968L1 |
| PDCD1 | m6A mRNA demethylase FTO regulates melanoma tumorigenicity and response to anti-PD-1 blockade | Nat Commun 2019 | Lenti | RC210364L2 |
| PDCD1 | Engineering PD-1-Presenting Platelets for Cancer Immunotherapy | Nano Lett. 2018 | Lenti | MR227347L4 |
| Pdcd1 | Blockade of Tumor-Expressed PD-1 Promotes Lung Cancer Growth | OncoImmunology 2017 | Lenti | MR227347L2V |
| PDCD10 | Endothelial cell clonal expansion in the development of cerebral cavernous malformations | Nat Commun 2019 | Lenti | RC205095L2 |
| PDCD10 | Loss of programmed cell death 10 activates tumor cells and leads to temozolomide-resistance in glioblastoma | J. Neurooncol. 2018 | Lenti | TL302576 |
| PDCD10 | MicroRNA-425-5p regulates chemoresistance in colorectal cancer cells via regulation of Programmed Cell Death 10 | J. Cell. Mol. Med. Dec 2015 | Lenti | RC221815L1 |
| PDE4B | Smurf2, an E3 ubiquitin ligase, interacts with PDE4B and attenuates liver fibrosis through miR-132 mediated CTGF inhibition | Biochim. Biophys. Acta 2017 | Lenti | RC218324L3 |
| PDE5A | Sildenafil prevents HDACi-induced Epstein-Barr virus reactivation through the PKG pathway in NK/T cell lymphoma; potential implications for HDACi-mediated fatal complications | Antiviral research 2021 | Lenti | TL316826 |
| PDE5A | Expression and Function of Phosphodiesterase Type 5 in Human Breast Cancer Cell Lines and Tissues: Implications for Targeted Therapy | Clin. Cancer Res. Dec 2015 | Lenti | TL316826 |
| PDGFB | Stromal platelet-derived growth factor receptor-β signaling promotes breast cancer metastasis in the brain | Cancer Research 2020 | Lenti | TL501604 |
| PDX1 | Development of new preclinical models to advance adrenocortical carcinoma research | Endocr. Relat. Cancer 2018 | Lenti | RC222354L2 |
| PECAM1 | PECAM1 Combines With CXCR4 to Trigger Inflammatory Cell Infiltration and Pulpitis Progression Through Activating the NF-κB Signaling Pathway | Frontiers in Cell and Developmental Biology 2020 | Lenti | TL711400V |
| PECAM1 | CD31 (PECAM-1) Serves as the Endothelial Cell-Specific Receptor of Clostridium perfringens β-Toxin | Cell Host & Microbe 2020 | Lenti | RC208654L3 |
| PECAM1 | CD31 (PECAM-1) Serves as the Endothelial Cell-Specific Receptor of Clostridium perfringens β-Toxin | Cell Host & Microbe 2020 | Lenti | MR227044L4 |
| PECAM1 | Cell-specific targeting by Clostridium perfringens β-toxin unraveled: the role of CD31 as the toxin receptor | bioRxiv 2019 | Lenti | RC208654L3 |
| PEG10 | PEG10 counteracts signaling pathways of TGF-β and BMP to regulate growth, motility and invasion of SW1353 chondrosarcoma cells | J. Bone Miner. Metab. 2018 | Lenti | RC229935L1 |
| PER1 | Light affects behavioral despair involving the clock gene Period 1 | bioRxiv 2020 | Lenti | TL501619 |
| PGK1 | Glucose Response by Stem Cell-Derived β Cells In Vitro Is Inhibited by a Bottleneck in Glycolysis | Cell Rep 2020 | Lenti | RC211172L1 |
| PGR | A mouse model engineered to conditionally express the progesterone receptor-B isoform | Genesis 2018 | Lenti | MR227418L1 |
| PGRMC1 | PGRMC1 Inhibits Progesterone-Evoked Proliferation and Ca2+ Entry Via STIM2 in MDA-MB-231 Cells | Int J Mol Sci 2020 | Lenti | TL316942 |
| PHGDH | Serine Biosynthesis Pathway Supports MYC-miR-494-EZH2 Feed-Forward Circuit Necessary to Maintain Metabolic and Epigenetic Reprogramming of Burkitt Lymphoma Cells | Cancers (Basel) 2020 | Lenti | TL507159 |
| PI3 | Elafin inhibits obesity, hyperglycemia, and liver steatosis in high-fat diet-treated male mice | Sci Rep 2020 | Lenti | RC203136L1V |
| PI4KA | A Forward Genetic Screen Targeting the Endothelium Reveals a Regulatory Role for the Lipid Kinase Pi4ka in Myelo- and Erythropoiesis | Cell Rep 2018 | Lenti | TL510615 |
| PIK3CA | Patient-Derived Xenografts and Matched Cell Lines Identify Pharmacogenomic Vulnerabilities in Colorectal Cancer | Clin. Cancer Res. 2019 | Lenti | RC213112L1 |
| PIM2 | PIM-2 protein kinase negatively regulates T cell responses in transplantation and tumor immunity | J. Clin. Invest. 2018 | Lenti | MR222342L2 |
| PIP5K1A | Clinical significance and functional role of transmembrane protein 47 (TMEM47) in chemoresistance of hepatocellular carcinoma | Int J Oncol 2020 | Lenti | RC227689L2V |
| PKM2 | PKM2 inhibition may reverse therapeutic resistance to transarterial chemoembolization in hepatocellular carcinoma | J. Exp. Clin. Cancer Res. 2020 | Lenti | TL302462 |
| PLCB4 | Functional screening implicates miR-371-3p and peroxiredoxin 6 in reversible tolerance to cancer drugs | Nat Commun 2016 | Lenti | TL310374 |
| PLCG2 | The Alzheimer\'s disease-associated protective Plcγ2-P522R variant promotes immune functions | Molecular neurodegeneration 2020 | Lenti | RC200442L1 |
| PLCG2 | The Alzheimer′ s disease-associated protective Plcγ2-P522R variant promotes beneficial microglial functions | bioRxiv 2020 | Lenti | RC200442L1 |
| pLenti-C-mGFP | Guanylate Binding Protein 5 (GBP5) regulates synovial fibroblast mediated inflammation and tissue destruction in rheumatoid arthritis | Arthritis & Rheumatology 2020 | Lenti | PS100071V |
| pLenti-C-mGFP | Clinical significance and functional role of transmembrane protein 47 (TMEM47) in chemoresistance of hepatocellular carcinoma | Int J Oncol 2020 | Lenti | PS100071V |
| pLenti-C-mGFP | Increased Tau Expression Correlates With IDH Mutation in Infiltrating Gliomas and Impairs Cell Migration | J. Neuropathol. Exp. Neurol. 2020 | Lenti | PS100071V |
| pLenti-C-mGFP-P2A-Pur | RIG-I Promotes Cell Death in Hepatocellular Carcinoma by Inducing M1 Polarization of Perineal Macrophages Through the RIG-I/MAVS/NF-κB Pathway | OncoTargets and therapy 2020 | Lenti | PS100093V |
| pLenti-C-mGFP-P2A-Puro | 11q Deletion or ALK Activity Curbs DLG2 Expression to Maintain an Undifferentiated State in Neuroblastoma | Cell Rep 2020 | Lenti | PS100093V |
| pLenti-C-mGFP-P2A-Puro | GRK5 is an Essential Co-repressor for Cardiac Mineralocorticoid Receptor Antagonism induced by Finerenone but not Eplerenone | preprints 2020 | Lenti | PS100093V |
| pLenti-C-Myc-DDK | Elafin inhibits obesity, hyperglycemia, and liver steatosis in high-fat diet-treated male mice | Sci Rep 2020 | Lenti | PS100064V |
| pLenti-C-Myc-DDK | Inhibition of endoglin exerts anti-tumor effects through the regulation of non-Smad TGF-β signaling in angiosarcoma | J. Invest. Dermatol. 2020 | Lenti | PS100064V |
| pLenti-C-Myc-DDK-P2A- Puro | DEAH-box polypeptide 32 promotes hepatocellular carcinoma progression via activating the β-catenin pathway | Research Square 2020 | Lenti | PS100092V |
| PLK4 | Polo‑like kinase 4 promotes tumorigenesis and induces resistance to radiotherapy in glioblastoma | Oncol. Rep. 2019 | Lenti | TL320644V |
| PMCA2 | Sphingomyelin-induced inhibition of the plasma membrane calcium ATPase causes neurodegeneration in type A Niemann-Pick disease | Mol. Psychiatry 2016 | Lenti | TL509635 |
| PNPLA2 | Adipose triglyceride lipase activity regulates cancer cell proliferation via AMP-kinase and mTOR signaling | Biochim Biophys Acta Mol Cell Biol Lipids 2020 | Lenti | TL302393 |
| PNPLA2 | Grasp55-/- mice display impaired fat absorption and resistance to high-fat diet-induced obesity | Nat Commun 2020 | Lenti | RC205708L3 |
| PNPLA2 | Alternative splicing switches STIM1 targeting to specialized membrane contact sites and modifies SOCE | bioRxiv 2020 | Lenti | RC205708L3 |
| Positive Control | Defining human cardiac transcription factor hierarchies using integrated single-cell heterogeneity analysis | Nat Commun 2018 | Lenti | PS100071V5 |
| POU3F1 | Delaying histone deacetylase response to injury accelerates conversion into repair Schwann cells and nerve regeneration | Nat Commun 2017 | Lenti | TL712899 |
| POU3F2 | Transcription factor POU3F2 regulates TRIM8 expression contributing to cellular functions implicated in schizophrenia | Mol. Psychiatry 2020 | Lenti | TL310273V |
| POU5F1 | OCT4 accelerates tumorigenesis through activating JAK/STAT signaling in ovarian cancer side population cells | Cancer Manag Res 2019 | Lenti | RC211998L1 |
| POU5F1 | OCT-4: a novel estrogen receptor-a collaborator that promotes tamoxifen resistance in breast cancer cells | Oncogene Apr 2016 | Lenti | TL310267 |
| PPARD | Pleotropic effects of PPARD accelerate colorectal tumor progression and invasion | bioRxiv 2018 | Lenti | RC214735L3 |
| PPARD | Pleotropic effects of PPARD accelerate colorectal tumor progression and invasion | bioRxiv 2018 | Lenti | MR207001L3 |
| PPARG | Abscisic acid regulates dormancy of prostate cancer disseminated tumor cells in the bone marrow | Neoplasia (New York, N.Y.) 2021 | Lenti | TL320459V |
| PPARG2 | Breast cancer-associated skeletal muscle mitochondrial dysfunction and lipid accumulation is reversed by PPARG | BioRxiv 2020 | Lenti | MR208132L4V |
| PPARGC1A | AMPK Maintains Cellular Metabolic Homeostasis through Regulation of Mitochondrial Reactive Oxygen Species | Cell Rep 2017 | Lenti | MR210710L2 |
| PPARGC1A | Skeletal muscle increases FGF21 expression in mitochondrial disorders to compensate for energy metabolic insufficiency by activating the mTOR-YY1-PGC1a pathway | Free Radic. Biol. Med. Apr 2015 | Lenti | TL509292 |
| PPM1G | Phosphatidylinositol-3 kinase-dependent translational regulation of Id1 involves the PPM1G phosphatase | Oncogene 2016 | Lenti | RC213685L1 |
| PPP2CA | AIM2 in regulatory T cells restrains autoimmune diseases | Nature 2021 | Lenti | MR204384L4 |
| PPP2CA | PP2A inhibition sensitizes cancer stem cells to ABL tyrosine kinase inhibitors in BCR-ABL+human leukemia | Sci Transl Med 2018 | Lenti | TL310229 |
| PRDM1 | NonO Is a Novel Co-factor of PRDM1 and Regulates Inflammatory Response in Monocyte Derived-Dendritic Cells | Front. Immunol. 2020 | Lenti | RC217363L1V |
| PRDM1 | Blimp-1 prolongs allograft survival without regimen via influencing T cell development in favor of regulatory T cells while suppressing Th1 | Mol. Immunol. 2018 | Lenti | TL510199 |
| PRDX4 | A reference map of the human proinsulin biosynthetic interaction network | bioRxiv 2019 | Lenti | TL510004 |
| PRDX5 | Peroxiredoxin 5 Silencing Sensitizes Dopaminergic Neuronal Cells to Rotenone via DNA Damage-Triggered ATM/p53/PUMA Signaling-Mediated Apoptosis | Cells 2019 | Lenti | RC210709L3 |
| PRKAB1 | AMP kinase promotes glioblastoma bioenergetics and tumour growth | Nat. Cell Biol. 2018 | Lenti | TL501734 |
| PRKDC | PRKDC regulates chemosensitivity and is a potential prognostic and predictive marker of response to adjuvant chemotherapy in breast cancer patients | Oncol. Rep. 2017 | Lenti | TL320478 |
| PRLR | Prolactin promotes fibrosis and pancreatic cancer progression | Cancer Res. 2019 | Lenti | TL310169 |
| PRMT2 | Huntingtin-mediated axonal transport requires arginine methylation by PRMT6 | Cell reports 2021 | Lenti | TL500997 |
| PRMT7 | PRMT7 methylates eukaryotic translation initiation factor 2α and regulates its role in stress granule formation | Mol. Biol. Cell 2019 | Lenti | RC201672L2 |
| PRMT7 | PRMT7 methylates eukaryotic translation initiation factor 2α and regulates its role in stress granule formation | Mol. Biol. Cell 2019 | Lenti | RC201672L1 |
| PRNP | Melatonin and 5-fluorouracil co-suppress colon cancer stem cells by regulating cellular prion protein-Oct4 axis | J. Pineal Res. 2018 | Lenti | TL302273 |
| PRNP | Hypoxia-induced expression of cellular prion protein improves the therapeutic potential of mesenchymal stem cells | Cell Death Dis 2016 | Lenti | TL302273 |
| PROM1 | CD133 Promotes Adhesion to the Ovarian Cancer Metastatic Niche | Cancer Growth Metastasis 2018 | Lenti | TL501745 |
| PRSS21 | Proteolytic activation of the protease-activated receptor (PAR)-2 by the GPI-anchored serine protease testisin | J. Biol. Chem. Dec 2014 | Lenti | TL310139 |
| PSMB5 | A conserved SUMO-Ubiquitin pathway directed by RNF4/SLX5-SLX8 and PIAS4/SIZ1 drives proteasomal degradation of topoisomerase DNA-protein crosslinks | bioRxiv 2019 | Lenti | RC209326L3 |
| PSMB5 | Inhibition of store-operated calcium entry by sub-lethal levels of proteasome inhibition is associated with STIM1/STIM2 degradation | Cell Calcium Mar 2016 | Lenti | TL310110 |
| PSMC5 | Hypoxia-induced increase in Sug1 leads to poor post-transplantation survival of allogeneic mesenchymal stem cells | FASEB J. 2020 | Lenti | TL711271V |
| PTEN | PTEN is a Predictive Biomarker of Trastuzumab Resistance and Prognostic Factor in HER2-overexpressing Gastroesophageal Adenocarcinoma | Research Square 2021 | Lenti | TL320498 |
| PTEN | Clinical and functional characterization of CXCR1/CXCR2 biology in the relapse and radiotherapy resistance of primary PTEN-deficient prostate carcinoma | NAR Cancer 2020 | Lenti | TL320498 |
| PTEN | PPARgamma agonists sensitize PTEN-deficient resistant lung cancer cells to EGFR tyrosine kinase inhibitors by inducing autophagy | Eur. J. Pharmacol. 2018 | Lenti | TL320498 |
| PTGES | Linking of mPGES-1 and iNOS activates stem-like phenotype in EGFR-driven epithelial tumor cells | Nitric Oxide 2017 | Lenti | RC202405L1 |
| PTGES | mPGES-1 in prostate cancer controls stemness and amplifies EGFR-driven oncogenicity | Endocr. Relat. Cancer Jun 2015 | Lenti | RC202405L1 |
| PTGS2 | Construction of COX-2 short hairpin RNA expression vector and its inhibitory effect on hepatic fibrosis | Biotechnology & Biotechnological Equipment 2018 | Lenti | TL710033 |
| PTP4A3 | Targeting ovarian cancer and endothelium with an allosteric PTP4A3 phosphatase inhibitor | Oncotarget 2018 | Lenti | TL320652 |
| PTPN1 | Targeting pancreatic islet PTP1B improves islet graft revascularization and transplant outcomes | Sci Transl Med 2019 | Lenti | TL310067V |
| PUF60 | PUF60 accelerates the progression of breast cancer through downregulation of PTEN expression | Cancer Manag Res 2019 | Lenti | TL307443 |
| PURA | Pur-alpha regulates cytoplasmic stress granule dynamics and ameliorates FUS toxicity | Acta Neuropathol. Jan 2016 | Lenti | TL310036V |
| RAB11A | Murine leukemia virus glycosylated Gag reduces murine SERINC5 protein expression at steady-state levels via endosome/lysosome pathway to counteract the SERINC5 antiretroviral activity | J. Virol. 2018 | Lenti | TL310015 |
| RAB11A | HIV-1 Nef antagonizes SERINC5 restriction by downregulation of SERINC5 via the endosome/lysosome system | J. Virol. 2018 | Lenti | TL310015 |
| RAB5A | Murine leukemia virus glycosylated Gag reduces murine SERINC5 protein expression at steady-state levels via endosome/lysosome pathway to counteract the SERINC5 antiretroviral activity | J. Virol. 2018 | Lenti | TL309987 |
| RAB5A | HIV-1 Nef antagonizes SERINC5 restriction by downregulation of SERINC5 via the endosome/lysosome system | J. Virol. 2018 | Lenti | TL309987 |
| RAB7A | Murine leukemia virus glycosylated Gag reduces murine SERINC5 protein expression at steady-state levels via endosome/lysosome pathway to counteract the SERINC5 antiretroviral activity | J. Virol. 2018 | Lenti | TL309983 |
| RAB7A | HIV-1 Nef antagonizes SERINC5 restriction by downregulation of SERINC5 via the endosome/lysosome system | J. Virol. 2018 | Lenti | TL309983 |
| RAB7A | Mevastatin blockade of autolysosome maturation stimulates LBH589-induced cell death in triple-negative breast cancer cells | Oncotarget 2017 | Lenti | RC201776L1 |
| RAC1 | CXCL12-induced rescue of cortical dendritic spines and cognitive flexibility | Elife 2020 | Lenti | TL320503 |
| RACK1 | AIM2 in regulatory T cells restrains autoimmune diseases | Nature 2021 | Lenti | MR204575L3 |
| RAD18 | AKT inhibition impairs PCNA ubiquitylation and triggers synthetic lethality in homologous recombination-deficient cells submitted to replication stress | Oncogene 2019 | Lenti | TL302132 |
| RAD18 | High expression of RAD18 in glioma induces radiotherapy resistance via down-regulating P53 expression | Biomed. Pharmacother. 2019 | Lenti | TL302132 |
| RAD18 | High expression of RAD18 in glioma induces radiotherapy resistance via down-regulating P53 expression | Biomed. Pharmacother. 2019 | Lenti | RC201700L1 |
| RAD21 | ASXL1 interacts with the cohesin complex to maintain chromatid separation and gene expression for normal hematopoiesis | Sci Adv 2017 | Lenti | TL501846 |
| RALA | The small G-protein RalA promotes progression and metastasis of triple-negative breast cancer | Breast cancer research : BCR 2021 | Lenti | TL309957V |
| RALA | The Small G-Protein RalA Promotes Progression and Metastasis of Triple Negative Breast Cancer | Research Square 2021 | Lenti | TL309957V |
| RALB | The small G-protein RalA promotes progression and metastasis of triple-negative breast cancer | Breast cancer research : BCR 2021 | Lenti | TL309956V |
| RALB | The Small G-Protein RalA Promotes Progression and Metastasis of Triple Negative Breast Cancer | Research Square 2021 | Lenti | TL309956V |
| RANBP2 | Ankyrin-G induces nucleoporin RanBP2/Nup358 to associate with the axon initial segment of neurons | J. Cell. Sci. 2019 | Lenti | TL501860 |
| RANGAP1 | The C9orf72 repeat expansion disrupts nucleocytoplasmic transport | Nature Sep 2015 | Lenti | RC204223L2 |
| RAPGEF2 | Disruption of MAGI2-RapGEF2-Rap1 signaling contributes to podocyte dysfunction in congenital nephrotic syndrome caused by mutations in MAGI2 | Kidney International 2019 | Lenti | TL316875 |
| RAPGEF4 | Regulation of Glucose-Dependent Golgi-Derived Microtubules by cAMP/EPAC2 Promotes Secretory Vesicle Biogenesis in Pancreatic β Cells | Curr. Biol. 2019 | Lenti | TL509420 |
| RARA | Retinoid receptor turnover mediated by sumoylation, ubiquitination and the valosin-containing protein is disrupted in glioblastoma | Sci Rep 2019 | Lenti | RC200430L1 |
| RARRES3 | RARRES3 suppressed metastasis through suppression of MTDH to regulate epithelial-mesenchymal transition in colorectal cancer | Am J Cancer Res Aug 2015 | Lenti | TL320510 |
| RASA2 | Hyperactivation of TORC1 Drives Resistance to the Pan-HER Tyrosine Kinase Inhibitor Neratinib in HER2-Mutant Cancers | Cancer Cell 2020 | Lenti | RC224076L3 |
| RASIP1 | Rasip1 controls lymphatic vessel lumen maintenance by regulating endothelial cell junctions | Development 2018 | Lenti | TL302100 |
| RBL1 | Association between copy-number alteration of +20q, -14q and -18p and cross-sensitivity to tyrosine kinase inhibitors in clear-cell renal cell carcinoma | Cancer Cell Int 2020 | Lenti | RC207017L3 |
| RBL1 | Intra-cisterna magna delivery of an AAV vector with the GLUT1 promoter in a pig recapitulates the physiological expression of SLC2A1 | Gene Ther 2020 | Lenti | RC207017L3V |
| RBM3 | Infants Uniquely Express High Levels of RBM3 and Other Cold-Adaptive Neuroprotectant Proteins in the Human Brain | Dev. Neurosci. 2018 | Lenti | TL309915 |
| RBM38 | RBM38 induces SIRT1 expression during hypoxia in non-small cell lung cancer cells by suppressing MIR34A expression | Biotechnol. Lett. 2019 | Lenti | TL317301V |
| RBM5 | Whole-transcriptome microarray analysis reveals regulation of Rab4 by RBM5 in neurons | Neuroscience 2017 | Lenti | TL704115 |
| RBPJ | Dnmt3b ablation impairs fracture repair through upregulation of Notch pathway | JCI Insight 2020 | Lenti | TL512813V |
| RBPJ | Direct reprogramming of fibroblasts into neural stem cells by single non-neural progenitor transcription factor Ptf1a | Nat Commun 2018 | Lenti | TL512813 |
| RD3 | HIV-1 viral protein R (Vpr) induces fatty liver in mice via LXRα and PPARα dysregulation: implications for HIV-specific pathogenesis of NAFLD | Sci Rep 2017 | Lenti | TL320630 |
| RETNLA | Hypoxia-Induced Mitogenic Factor Acts as a Nonclassical Ligand of Calcium-Sensing Receptor, Therapeutically Exploitable for Intermittent Hypoxia-Induced Pulmonary Hypertension | Hypertension 2017 | Lenti | TL711770 |
| RFX7 | The transcription factor Rfx7 limits metabolism of NK cells and promotes their maintenance and immunity | Nat. Immunol. 2018 | Lenti | RC211086L1 |
| RIOK1 | Targeting posttranslational modifications of RioK1 inhibits the progression of colorectal and gastric cancers | bioRxiv 2017 | Lenti | TL320739 |
| RIPK3 | A novel neurodegenerative spectrum disorder in patients with MLKL deficiency | Cell Death Dis 2020 | Lenti | RC209549L3 |
| RNF144A | RNF144A functions as a tumor suppressor in breast cancer through ubiquitin ligase activity-dependent regulation of stability and oncogenic functions of HSPA2 | Cell Death Differ. 2019 | Lenti | TL309788 |
| RNF144A | RBR-type E3 ubiquitin ligase RNF144A targets PARP1 for ubiquitin-dependent degradation and regulates PARP inhibitor sensitivity in breast cancer cells | Oncotarget 2017 | Lenti | TL309788 |
| RORA | Sertoli cell specific knockdown of RAR-related orphan receptor (ROR) alpha at puberty reduces sperm count in rats | Gene 2017 | Lenti | TL705407 |
| RPA3 | Elevated Expression of RPA3 Is Involved in Gastric Cancer Tumorigenesis and Associated with Poor Patient Survival | Dig. Dis. Sci. 2017 | Lenti | TL316699 |
| RPS27A | RPS27a enhances EBV-encoded LMP1-mediated proliferation and invasion by stabilizing of LMP1 | Biochem. Biophys. Res. Commun. 2017 | Lenti | TL309716 |
| RRM2 | RRM2 protects against ferroptosis and is a tumor biomarker for liver cancer | Cancer cell international 2020 | Lenti | TL309700 |
| RSF1 | RSF1 regulates the proliferation and paclitaxel resistance via modulating NF-κB signaling pathway in nasopharyngeal carcinoma | J Cancer 2017 | Lenti | RC218432L2 |
| RTEL1 | RTEL1 Influences the Abundance and Localization of TERRA RNA | bioRxiv 2020 | Lenti | RC214507L3 |
| RUNX1 | rs11671784 G/A variation in miR-27a decreases chemo-sensitivity of bladder cancer by decreasing miR-27a and increasing the target RUNX-1 expression | Biochem. Biophys. Res. Commun. Mar 2015 | Lenti | RC223809L1 |
| RUNX3 | Ecto-NTPDase CD39 is a negative checkpoint that inhibits follicular helper cell generation | J. Clin. Invest. 2020 | Lenti | TL309682 |
| RXFP1 | Serelaxin alleviates cardiac fibrosis through inhibiting endothelial-to-mesenchymal transition via RXFP1 | Theranostics 2020 | Lenti | TL301865 |
| RXFP1 | Expression of RXFP1 is Decreased in Idiopathic Pulmonary Fibrosis: Implications for Relaxin-Based Therapies | Am. J. Respir. Crit. Care Med. Jun 2016 | Lenti | RC211338L1 |
| RXRB | Prominent role of RAB39A-RXRB axis in cancer development and stemness | Oncotarget 2018 | Lenti | RC200516L3 |
| S100A14 | Increased S100A15 expression and decreased DNA methylation of its gene promoter are involved in high metastasis potential and poor outcome of lung adenocarcinoma | Oncotarget 2017 | Lenti | TL318900 |
| S100A8 | Hypoxia-Induced S100A8 Expression Activates Microglial Inflammation and Promotes Neuronal Apoptosis | International Journal of Molecular Sciences 2021 | Lenti | TL519129 |
| S100A9 | S100A9 regulates cisplatin chemosensitivity of squamous cervical cancer cells and related mechanism | Cancer Manag Res 2018 | Lenti | TL316713 |
| S100A9 | The role ofcalgranulin Bgene on the biological behavior of squamous cervical cancer in vitro and in vivo | Cancer Manag Res 2018 | Lenti | TL316713 |
| S100G | 17β-estradiol binding to ERα promotes the progression of prolactinoma through estrogen-response element-induced CaBP-9k up-regulation | Biosci. Rep. 2020 | Lenti | TL709169 |
| S100G | Modulation effects of black-vinegar based supplement against a high-fat dietary habit: antiobesity/hypolipidemic, antioxidative, and energy-metabolism effects | J. Sci. Food Agric. 2020 | Lenti | TL709169 |
| SAA3 | Serum Amyloid A3 Secreted by Preosteoclasts Inhibits Parathyroid Hormone-Stimulated cAMP Signaling in Murine Osteoblasts | J. Biol. Chem. Dec 2015 | Lenti | TL501964 |
| SALL1 | SALL1 expression in acute myeloid leukemia | Oncotarget 2018 | Lenti | TL309658 |
| SALL4 | Inflammatory Micro-environment Contributes to Stemness Properties and Metastatic Potential of HCC via the NF-κB/miR-497/SALL4 Axis | Mol Ther Oncolytics 2019 | Lenti | TL301854 |
| SALL4 | Inflammatory microenvironment contributes to stemness properties and metastatic potential of hepatocellular carcinoma via NF-κB/miR-497/SALL4 axis | Molecular Therapy - Oncolytics 2019 | Lenti | TL301854 |
| SAV1 | Dysregulation of PI3K and hippo signaling pathways synergistically induces chronic pancreatitis via Ctgf upregulation | The Journal of clinical investigation 2021 | Lenti | MR206033L4 |
| SCG3 | Carboxypeptidase E and Secretogranin III Coordinately Facilitate Efficient Sorting of Proopiomelanocortin to the Regulated Secretory Pathway in AtT20 Cells | Mol. Endocrinol 2016 | Lenti | TL516044 |
| Scrambled Control | Gene Amplification-Associated Overexpression of the Selenoprotein tRNA Enzyme TRIT1 Confers Sensitivity to Arsenic Trioxide in Small-Cell Lung Cancer | Cancers 2021 | Lenti | TR30021 |
| Scrambled Control | MDMX acts as a pervasive preleukemic-to-acute myeloid leukemia transition mechanism | Cancer cell 2021 | Lenti | TR30021 |
| Scrambled Control | Integrative network analysis reveals USP7 haploinsufficiency inhibits E-protein activity in pediatric T-lineage acute lymphoblastic leukemia (T-ALL) | Scientific reports 2021 | Lenti | TR30021 |
| Scrambled Control | Mesenchymal stem cell-derived interleukin-28 drives the selection of apoptosis resistant bone metastatic prostate cancer | Nature communications 2021 | Lenti | TR30033 |
| Scrambled Control | Prodromal Alzheimer\'s Disease: Constitutive Upregulation of Neuroglobin Prevents the Initiation of Alzheimer\'s Pathology | Frontiers in neuroscience 2020 | Lenti | TR30021 |
| Scrambled Control | Alzheimer\'s-associated PU.1 expression levels regulate microglial inflammatory response | Neurobiology of disease 2020 | Lenti | TR30013 |
| Scrambled Control | Analysis of ADAM9 Regulation and Function in Vestibular Schwannoma Primary Cells | Research Square 2020 | Lenti | TR30021V |
| Scrambled Control | UDP-glucose, a cellular danger signal, and nucleotide receptor P2Y14 enhance the invasion of human extravillous trophoblast cells | Placenta 2020 | Lenti | TR30021V |
| Scrambled Control | GULP1 regulates the NRF2-KEAP1 signaling axis in urothelial carcinoma | Sci Signal 2020 | Lenti | TR30021 |
| Scrambled Control | Norrin mediates tumor-promoting and -suppressive effects in glioblastoma via Notch and WNT | J. Clin. Invest. 2020 | Lenti | TR30021 |
| Scrambled Control | Heat Shock Protein 47 Maintains Cancer Cell Growth by Inhibiting the Unfolded Protein Response Transducer IRE1α | Mol. Cancer Res. 2020 | Lenti | TR30021 |
| Scrambled Control | GRSF1 suppresses cell senescence | Aging (Albany NY) 2018 | Lenti | TR30021V |
| SDC1 | Sphingosine 1-phosphate regulates proliferation, cell cycle and apoptosis of hepatocellular carcinoma cells via syndecan-1 | Prog. Biophys. Mol. Biol.2017 | Lenti | TL309598 |
| SDC1 | Sphingosine-1-phosphate induced epithelial-mesenchymal transition of hepatocellular carcinoma via an MMP-7/ syndecan-1/TGF-ß autocrine loop | Oncotarget 2016 | Lenti | TL309598 |
| SDCBP | Epigenetic regulation of TGF-β-induced EMT by JMJD3/KDM6B histone H3K27 demethylase | Oncogenesis 2021 | Lenti | TL309594 |
| SDCBP | Lung Adenocarcinoma Syndecan-2 Potentiates Cell Invasiveness | Am. J. Respir. Cell Mol. Biol. 2018 | Lenti | RC215390L1 |
| SDCBP | Syntenin promotes VEGF-induced VEGFR2 endocytosis and angiogenesis by increasing ephrin-B2 function in endothelial cells | Oncotarget 2017 | Lenti | TL309594 |
| SDCBP | Syntenin regulates TGF-ß1-induced Smad activation and the epithelial-to-mesenchymal transition by inhibiting caveolin-mediated TGF-ß type I receptor internalization | Oncogene Apr 2015 | Lenti | TL309594 |
| SDCBP2 | Lung Adenocarcinoma Syndecan-2 Potentiates Cell Invasiveness | Am. J. Respir. Cell Mol. Biol. 2018 | Lenti | RC218898L2 |
| SEMA3C | Regulation of Sema3c and the Interaction between Cardiac Neural Crest and Second Heart Field during Outflow Tract Development | Sci Rep 2017 | Lenti | RC205269L1 |
| SEMA6A | Nrf2 in ischemic neurons promotes retinal vascular regeneration through regulation of semaphorin 6A | Proc. Natl. Acad. Sci. U.S.A. Dec 2015 | Lenti | TL510568 |
| SENP2 | SUMOylation determines the voltage required to activate cardiac IKs channels | Proc. Natl. Acad. Sci. U.S.A. 2017 | Lenti | TL517117 |
| SENP2 | Accumulation of histone variant H3. 3 with age is associated with profound changes in the histone methylation landscape | Nucleic Acids Research 2017 | Lenti | TL517117 |
| SERPINH1 | Heat shock protein 47 promotes tumor survival and therapy resistance by modulating AKT signaling via PHLPP1 in colorectal cancer | Cancer Biol Med 2020 | Lenti | TL316478 |
| SH2D3C | Up-regulation of NSP3 by Oligomeric Aβ Accelerates Neuronal Death Through Cas-independent Rap1A Activation | Neuroscience 2018 | Lenti | TL502696 |
| SH3BP2 | Myo1f, an Unconventional Long-Tailed Myosin, Is a New Partner for the Adaptor 3BP2 Involved in Mast Cell Migration | Front Immunol 2019 | Lenti | RC205759L2 |
| SIRT6 | Deacetylation of Ku70 by SIRT6 attenuates Bax-mediated apoptosis in hepatocellular carcinoma | Biochem. Biophys. Res. Commun 2017 | Lenti | RC202833L1 |
| SKA2 | Upregulation of microRNA‑520a‑3p inhibits the proliferation, migration and invasion via spindle and kinetochore associated 2 in gastric cancer | Oncology Letters 2019 | Lenti | RC222296L3 |
| SKP2 | OCT-4: a novel estrogen receptor-a collaborator that promotes tamoxifen resistance in breast cancer cells | Oncogene Apr 2016 | Lenti | TL301684 |
| SLC10A1 | Apical Sodium-Dependent Bile Acid Cotransporter, A Novel Transporter of Indocyanine Green, and Its Application in Drug Screening | Int J Mol Sci 2020 | Lenti | RC210241L2 |
| SLC10A1 | Role of Sodium Taurocholate Cotransporting Polypeptide as a New Reporter and Drug-Screening Platform: Implications for Preventing Hepatitis B Virus Infections | Mol Imaging Biol 2019 | Lenti | RC210241L2 |
| SLC10A1 | N-linked glycosylation is not essential for sodium taurocholate cotransporting polypeptide to mediate hepatitis B virus infection in vitro | J. Virol. 2018 | Lenti | TL309420 |
| SLC10A2 | Apical Sodium-Dependent Bile Acid Cotransporter, A Novel Transporter of Indocyanine Green, and Its Application in Drug Screening | Int J Mol Sci 2020 | Lenti | RC221202L2 |
| SLC15A2 | Dipeptide species regulate p38MAPK-Smad3 signalling to maintain chronic myelogenous leukaemia stem cells | Nat Commun Aug 2015 | Lenti | TL503323 |
| SLC16A1 | Metabolic heterogeneity confers differences in melanoma metastatic potential | Nature 2020 | Lenti | TL309405 |
| SLC17A5 | Nitrate uptake and metabolism in human skeletal muscle cell cultures | Nitric Oxide 2019 | Lenti | TL309394 |
| SLC1A5 | Tumor-Repopulating Cells Induce PD-1 Expression in CD8+T Cells by Transferring Kynurenine and AhR Activation | Cancer Cell 2018 | Lenti | TL516694 |
| Slc2a1 | The insulin-like growth factor I receptor regulates glucose transport by astrocytes | Glia 2016 | Lenti | TL511086 |
| Slc2a1 | The insulin-like growth factor I receptor regulates glucose transport by astrocytes | Glia 2016 | Lenti | TL501102 |
| SLC2A1 | A DERL3-associated defect in the degradation of SLC2A1 mediates the Warburg effect | Nat Commun 3608 5 . April 2014 | Lenti | TL309344 |
| SLC5A1 | Dual-Target Compounds against Type 2 Diabetes Mellitus: Proof of Concept for Sodium Dependent Glucose Transporter (SGLT) and Glycogen Phosphorylase (GP) Inhibitors | Pharmaceuticals (Basel, Switzerland) 2021 | Lenti | RC221312L1V |
| SLC5A2 | Dual-Target Compounds against Type 2 Diabetes Mellitus: Proof of Concept for Sodium Dependent Glucose Transporter (SGLT) and Glycogen Phosphorylase (GP) Inhibitors | Pharmaceuticals (Basel, Switzerland) 2021 | Lenti | RC224822L1V |
| SLC7A11 | System χc- overexpression prevents 2-deoxy-d-ribose-induced β-cell damage | Free Radic. Biol. Med. 2020 | Lenti | RR208495L4 |
| SLIT1 | Suppression of Slit3 induces tumor proliferation and chemoresistance in hepatocellular carcinoma through activation of GSK3β/β-catenin pathway | BMC Cancer 2018 | Lenti | TL502069 |
| SLITRK2 | Opposite Control of Excitatory and Inhibitory Synapse Formation by Slitrk2 and Slitrk5 on Dopamine Neurons Modulates Hyperactivity Behavior | Cell Rep 2020 | Lenti | TL514163 |
| SLITRK5 | Opposite Control of Excitatory and Inhibitory Synapse Formation by Slitrk2 and Slitrk5 on Dopamine Neurons Modulates Hyperactivity Behavior | Cell Rep 2020 | Lenti | TL505056 |
| SMAD2 | Adult cardiac stem cells are multipotent and robustly myogenic: c-kit expression is necessary but not sufficient for their identification | Cell Death Differ. 2017 | Lenti | RR212493L2 |
| SMAD3 | Aurora-A kinase oncogenic signaling mediates TGF-β-induced triple-negative breast cancer plasticity and chemoresistance | Oncogene 2021 | Lenti | TL309254 |
| SMC1A | ASXL1 interacts with the cohesin complex to maintain chromatid separation and gene expression for normal hematopoiesis | Sci Adv 2017 | Lenti | TL513033 |
| SMO | Interference with SMO increases chemotherapy drug sensitivity of A2780/DDP cells by inhibiting the Hh/Gli signaling pathway | J. Cell. Biochem. 2020 | Lenti | TL309234 |
| SMO | Targeting Smoothened Sensitizes Gastric Cancer to Chemotherapy in Experimental Models | Med. Sci. Monit 2017 | Lenti | MR210692L2 |
| SMO | Targeting Smoothened Sensitizes Gastric Cancer to Chemotherapy in Experimental Models | Med. Sci. Monit 2017 | Lenti | TL510788 |
| SMOX | Increased polyamines as protective disease modifiers in Congenital Muscular Dystrophy | Hum. Mol. Genet. 2018 | Lenti | RC214652L2 |
| SMPD3 | The cationic small molecule GW4869 is cytotoxic to high phosphatidylserine-expressing myeloma cells | Br. J. Haematol 2017 | Lenti | TL301492 |
| SNAI1 | Aurora-A kinase oncogenic signaling mediates TGF-β-induced triple-negative breast cancer plasticity and chemoresistance | Oncogene 2021 | Lenti | TL309226 |
| SNAI1 | FBXO22 possesses both pro-tumorigenic and anti-metastatic roles in breast cancer progression | Cancer Res. 2018 | Lenti | TL309226 |
| SNAI1 | Lysyl Oxidase-like Protein LOXL2 Promotes Lung Metastasis of Breast Cancer | Cancer Res. 2017 | Lenti | MR203505L2V |
| SNAI1 | Endothelial Snail Regulates Capillary Branching Morphogenesis via Vascular Endothelial Growth Factor Receptor 3 Expression | PLoS Genet. Jul 2015 | Lenti | TL502087 |
| SNAI2 | SLUG Directs the Precursor State of Human Brain Tumor Stem Cells | Cancers (Basel) 2019 | Lenti | RC202365L1 |
| SNCA | a-Synuclein, a chemoattractant, directs microglial migration via H2O2-dependent Lyn phosphorylation | Proc. Natl. Acad. Sci. U.S.A. Apr 2015 | Lenti | TL710189 |
| SNX27 | STXBP6, reciprocally regulated with autophagy, reduces triple negative breast cancer aggressiveness | Clinical and Translational Medicine 2020 | Lenti | RC218477L4V |
| SORL1 | SORLA regulates endosomal trafficking and oncogenic fitness of HER2 | Nat Commun 2019 | Lenti | TL309181 |
| SORL1 | SORLA-driven endosomal trafficking regulates the oncogenic fitness of HER2 | bioRxiv 2018 | Lenti | TL309181 |
| SOX10 | m6A mRNA demethylase FTO regulates melanoma tumorigenicity and response to anti-PD-1 blockade | Nat Commun 2019 | Lenti | RC203545L2 |
| SOX2 | Reciprocal activation of HEY1 and NOTCH4 under SOX2 control promotes EMT in head and neck squamous cell carcinoma | International Journal of Oncology 2020 | Lenti | RC200757L3 |
| SOX2 | Arsenic promotes the COX2/PGE2-SOX2 axis to increase the malignant stemness properties of urothelial cells | Int. J. Cancer 2018 | Lenti | TL309173 |
| Sox2 | YAP1 and COX2 coordinately regulate urothelial cancer stem-like cells | Cancer Res.2017 | Lenti | TL515613 |
| SOX7 | Sox7 is involved in antibody-dependent endothelial cell activation and renal allograft injury via the Jagged1-Notch1 pathway | Exp. Cell Res. 2019 | Lenti | TL301454 |
| SOX9 | Sox9 regulates the luminal stem/progenitor cell properties of salivary glands | Experimental Cell Research 2019 | Lenti | TL511411 |
| SOX9 | Incomplete radiofrequency ablation promotes the development of CD133+ cancer stem cells in hepatocellular carcinoma cell line HepG2 via inducing SOX9 expression | HBPD INT 2018 | Lenti | TL309170 |
| SOX9 | SOX9 Transcriptionally Regulates mTOR-Induced Proliferation of Basal Cell Carcinomas | J. Invest. Dermatol. 2018 | Lenti | TL309170 |
| SP1 | Resveratrol Represses Pokemon Expression in Human Glioma Cells | Molecular Neurobiology Jan 2015 | Lenti | TL301453 |
| SP7 | Synergistic Effects of Controlled-Released BMP-2 and VEGF from nHAC/PLGAs Scaffold on Osteogenesis | BioMed Research International 2018 | Lenti | TL514041 |
| SPANXD | The multifunctional role of SPANX-A/D protein subfamily in the promotion of pro-tumoural processes in human melanoma | Scientific reports 2021 | Lenti | TL318845 |
| SPAST | Spastin Contributes to Neural Development through the Regulation of Microtubule Dynamics in the Primary Cilia of Neural Stem Cells | Neuroscience 2019 | Lenti | TL511715 |
| SPI1 | Transcriptional regulation of the proto-oncogene Zfp521 by SPI1 (PU.1) and HOXC13 | Genesis 2016 | Lenti | TL316738 |
| SPP1 | Secreted phosphoprotein-1 accelerates the progression of human colorectal cancer through activating β-catenin signaling | Oncology letters 2021 | Lenti | TL313664 |
| Spry4 | Novel Function of Sprouty4 as a Regulator of Stemness and Differentiation of Embryonic Stem Cells | Development & Reproduciton 2016 | Lenti | TL509780 |
| SQLE | Squalene epoxidase drives NAFLD-induced hepatocellular carcinoma and is a pharmaceutical target | Sci Transl Med 2018 | Lenti | TL309122 |
| SQSTM1 | Contribution of p62/SQSTM1 to PDGF-BB-induced myofibroblast-like phenotypic transition in vascular smooth muscle cells lacking Smpd1 gene | Cell Death Dis 2018 | Lenti | TL515047 |
| SREBF2 | miR-33a Mediates the Anti-Tumor Effect of Lovastatin in Osteosarcoma by Targeting CYR61 | Cell. Physiol. Biochem. 2018 | Lenti | TL309116 |
| SRF | Pseudotemporal Ordering of Single Cells Reveals Metabolic Control of Postnatal β Cell Proliferation | Cell Metab. 2017 | Lenti | MR208120L2 |
| SRSF5 | The evolution of alternative splicing in glioblastoma under therapy | Genome biology 2021 | Lenti | RC218652L2 |
| ST8SIA3 | Glycolipids Recognized by A2B5 Antibody Promote Proliferation, Migration, and Clonogenicity in Glioblastoma Cells | Cancers (Basel) 2019 | Lenti | TL301359 |
| STAT1 | Resistance to histone deacetylase inhibitors confers hypersensitivity to oncolytic reovirus therapy | Blood Adv 2020 | Lenti | TL301349V |
| STAT1 | Blockade of IDO-kynurenine-AhR metabolic circuitry abrogates IFN-γ-induced immunologic dormancy of tumor-repopulating cells | Nat Commun 2017 | Lenti | TL301349 |
| STAT3 | PD-L1 is overexpressed on breast cancer stem cells through notch3/mTOR axis | OncoImmunology 2020 | Lenti | TL301348V |
| STAT3 | Interleukin-23 promotes the migration and invasion of gastric cancer cells by inducing epithelial-to-mesenchymal transition via the STAT3 pathway | Biochem. Biophys. Res. Commun. 2018 | Lenti | TL301348 |
| STAT3 | Microenvironmental interleukin-6 suppresses toll-like receptor signaling in human leukemia cells through miR-17/19A | Blood Jun 2015 | Lenti | TL301348 |
| STC1 | Stanniocalcin 1 is a phagocytosis checkpoint driving tumor immune resistance | Cancer cell 2021 | Lenti | MR203105L1 |
| STIM1 | STIM Protein-NMDA2 Receptor Interaction Decreases NMDA-Dependent Calcium Levels in Cortical Neurons | Cells 2020 | Lenti | TL309049 |
| STIM2 | STIM Protein-NMDA2 Receptor Interaction Decreases NMDA-Dependent Calcium Levels in Cortical Neurons | Cells 2020 | Lenti | TL301342 |
| STIP1 | Stress-induced phosphoprotein 1 promotes pancreatic cancer progression through activation of the FAK/AKT/MMP signaling axis | Pathology - Research and Practice 2019 | Lenti | TL309048 |
| STK19 | Pharmacological Targeting of STK19 Inhibits Oncogenic NRAS-Driven Melanomagenesis | Cell 2019 | Lenti | RC219373L3 |
| STMN1 | The microRNA-210-Stathmin1 Axis Decreases Cell Stiffness to Facilitate the Invasiveness of Colorectal Cancer Stem Cells | Cancers 2021 | Lenti | RC205073L3 |
| STX12 | Functional screening implicates miR-371-3p and peroxiredoxin 6 in reversible tolerance to cancer drugs | Nat Commun 2016 | Lenti | TL301328 |
| STXBP6 | STXBP6, reciprocally regulated with autophagy, reduces triple negative breast cancer aggressiveness | Clinical and Translational Medicine 2020 | Lenti | RC209598L3V |
| SULT1A1 | Identification and targeting of selective vulnerability rendered by tamoxifen resistance | Breast Cancer Res. 2020 | Lenti | RC201601L1 |
| SYK | Distinct Signaling Pathways Regulate TREM2 Phagocytic and NFκB Antagonistic Activities | Front Cell Neurosci 2019 | Lenti | TL320543 |
| SYK | SYK-targeted dendritic cell-mediated cytotoxic T lymphocytes enhance the effect of immunotherapy on retinoblastoma | J. Cancer Res. Clin. Oncol. 2018 | Lenti | RC200413L3 |
| Syvn1 | The ubiquitin-proteasome system functionally links neuronal Tomosyn-1 to dendritic morphology | J. Biol. Chem. 2017 | Lenti | TL704173 |
| TARDBP | Senataxin mutations elicit motor neuron degeneration phenotypes and yield TDP-43 mislocalization in ALS4 mice and human patients | Acta Neuropathol. 2018 | Lenti | RC210639L2 |
| TBL1X | Transducin β-like protein 1 controls multiple oncogenic networks in diffuse large B-cell lymphoma | haematol 2020 | Lenti | TL316751 |
| TBX20 | Tbx20 controls the expression of the KCNH2 gene and of hERG channels | Proc. Natl. Acad. Sci. U.S.A 2017 | Lenti | RC212412L2 |
| TBX20 | Tbx20 controls the expression of the KCNH2 gene and of hERG channels | Proc. Natl. Acad. Sci. U.S.A 2017 | Lenti | TL503288 |
| TBX21 | Transcription Factor T-bet in B Cells Modulates Germinal Center Polarization and Antibody Affinity Maturation in Response to Malaria | Cell Rep 2019 | Lenti | RC207902L4V |
| TBX5 | Myocyte-specific enhancer factor 2c triggers transdifferentiation of adipose tissue-derived stromal cells into spontaneously beating cardiomyocyte-like cells | Scientific reports 2021 | Lenti | MR227369L4V |
| TBX5 | Defining human cardiac transcription factor hierarchies using integrated single-cell heterogeneity analysis | Nat Commun 2018 | Lenti | RC216520L2 |
| Tcf7l2 | Macrophage TCF-4 Coactivates p65 to Potentiate Chronic Inflammation and Insulin Resistance in Mice | Clin. Sci. Apr 2016 | Lenti | MR207325L1 |
| TCOF1 | Stable Acinar Progenitor Cell Model Identifies Treacle-Dependent Radioresistance | Radiat. Res. 2019 | Lenti | TL704731V |
| TDP2 | TOP2β-Dependent Nuclear DNA Damage Shapes Extracellular Growth Factor Responses via Dynamic AKT Phosphorylation to Control Virus Latency | Mol. Cell 2019 | Lenti | RC202015L1 |
| TDP2 | Topoisomerase 2 [beta]-dependent nuclear DNA damage shapes extracellular growth factor responses through AKT phosphorylation dynamics to control virus latency | bioRxiv 2019 | Lenti | RC202015L1 |
| TEAD1 | YAP1 plays a key role of the conversion of normal fibroblasts into cancer-associated fibroblasts that contribute to prostate cancer progression | J. Exp. Clin. Cancer Res. 2020 | Lenti | TL513813 |
| TEAD1 | Analysis of chromatin accessibility uncovers TEAD1 as a regulator of migration in human glioblastoma | Nat Commun 2018 | Lenti | RC215492L1 |
| TERF2 | Telomere damage promotes vascular smooth muscle cell senescence and immune cell recruitment after vessel injury | Communications biology 2021 | Lenti | RC223601L1 |
| TET1 | Vitamin C Promotes Astrocyte Differentiation Through DNA Hydroxymethylation | Stem Cells 2018 | Lenti | TL706196 |
| TET2 | Reprogramming of DNA methylation at NEUROD2-bound sequences during cortical neuron differentiation | Sci Adv 2019 | Lenti | TL513547 |
| TET2 | Tet methylcytosine dioxygenase 2 inhibits atherosclerosis via upregulation of autophagy in ApoE-/- mice | Oncotarget 2016 | Lenti | RC215770L1 |
| TET2 | Tet methylcytosine dioxygenase 2 inhibits atherosclerosis via upregulation of autophagy in ApoE-/- mice | Oncotarget 2016 | Lenti | TL303734 |
| TFAM | HO-1/CO system and embryonic stem cell differentiation and maturation into cardiomyocytes | Antioxid. Redox Signal. Jan 2016 | Lenti | MR203015L2 |
| TGFBR1 | miR-140-5p alleviates the aggressive progression of Wilms' tumor through directly targeting TGFBR1 gene | Cancer Manag Res 2019 | Lenti | TL320549 |
| TIMD4 | Autophagy-related protein Vps34 controls the homeostasis and function of antigen cross-presenting CD8α(+) dendritic cells | Proc. Natl. Acad. Sci. U.S.A. 2017 | Lenti | MR222206L1 |
| TIMP-1 | Targeting tissue inhibitor of metalloproteinase 1/2 using a shRNA lentiviral system offers a novel treatment strategy against hepatic fibrosis | Int J Clin Exp Med 2016 | Lenti | TL712176 |
| TIMP-2 | Targeting tissue inhibitor of metalloproteinase 1/2 using a shRNA lentiviral system offers a novel treatment strategy against hepatic fibrosis | Int J Clin Exp Med 2016 | Lenti | TL710553 |
| TJP1 | BMP signaling is required for postnatal murine hematopoietic stem cell self-renewal | Haematologica 2020 | Lenti | TL516754 |
| TLR2 | Inflammasome Priming Mediated via Toll-Like Receptors 2 and 4, Induces Th1-Like Regulatory T Cells in De Novo Autoimmune Hepatitis | Front Immunol 2018 | Lenti | TL320553 |
| TLR2 | Selective disruption of TLR2/MyD88 interaction inhibits inflammation and attenuates Alzheimer's pathology | J. Clin. Invest. 2018 | Lenti | RC207597L1 |
| TLR4 | Inflammasome Priming Mediated via Toll-Like Receptors 2 and 4, Induces Th1-Like Regulatory T Cells in De Novo Autoimmune Hepatitis | Front Immunol 2018 | Lenti | TL320555 |
| TLR9 | Inflammasome Priming Mediated via Toll-Like Receptors 2 and 4, Induces Th1-Like Regulatory T Cells in De Novo Autoimmune Hepatitis | Front Immunol 2018 | Lenti | TL301076 |
| TMEM163 | Transmembrane 163 (TMEM163) protein effluxes zinc | bioRxiv 2019 | Lenti | TL307341 |
| TMEM173 | Epigenetic reprogramming of tumor cell-intrinsic STING function sculpts antigenicity and T cell recognition of melanoma | Proceedings of the National Academy of Sciences of the United States of America 2021 | Lenti | TL307876V |
| TMPRSS5 | Potential differences in cleavage of the S protein and type-1 interferon together control human coronavirus infection, propagation, and neuropathology within the central nervous system | Journal of virology 2021 | Lenti | RC223774L3V |
| TNF | Improved insulin sensitivity in obese-diabetic mice viachitosan Nanomicelles mediated silencing of pro-inflammatory Adipocytokines | Nanomedicine : nanotechnology, biology, and medicine 2021 | Lenti | TL515379 |
| TNF | Local TNF causes NFATc1-dependent cholesterol-mediated podocyte injury | J. Clin. Invest. 2016 | Lenti | RC206983L1 |
| TNFRSF1A | Quantitative analysis of competitive cytokine signaling predicts tissue thresholds for the propagation of macrophage activation | Sci Signal 2018 | Lenti | TL308734 |
| TNFRSF1A | TNF-α receptor 1 knockdown in subfornical organ ameliorates sympathetic excitation and cardiac hemodynamics in heart failure rats | Am. J. Physiol. Heart Circ. Physiol. 2017 | Lenti | TL709687 |
| Tnfrsf21 | Induction of microRNA-17-5p by p53 protects against renal ischemia-reperfusion injury by targeting death receptor 6 | Kidney Int. 2017 | Lenti | TL706747 |
| TNS4 | CTEN Induces Tumour Cell Invasion and Survival and Is Prognostic in Radiotherapy-Treated Head and Neck Cancer | Cancers (Basel) 2020 | Lenti | TL300896 |
| Tomo1 | Dynamic Partitioning of Synaptic Vesicle Pools by the SNARE-Binding Protein Tomosyn | J. Neurosci. 2016 | Lenti | TL518079 |
| TOP2A | Spatial Chromosome Folding and Active Transcription Drive DNA Fragility and Formation of Oncogenic MLL Translocations | Mol. Cell 2019 | Lenti | TL308699 |
| TOP2B | Spatial Chromosome Folding and Active Transcription Drive DNA Fragility and Formation of Oncogenic MLL Translocations | Mol. Cell 2019 | Lenti | TL308698 |
| TOX | TOX is a critical regulator of tumour-specific T cell differentiation | Nature 2019 | Lenti | MR208435L2 |
| TP53 | High expression of RAD18 in glioma induces radiotherapy resistance via down-regulating P53 expression | Biomed. Pharmacother. 2019 | Lenti | RC225604L1 |
| TP53 | ATR suppresses the pro-tumorigenic functions of breast stromal fibroblasts | Oncotarget 2018 | Lenti | RC225604L1 |
| TP53 | Endothelial p53 Deletion Improves Angiogenesis and Prevents Cardiac Fibrosis and Heart Failure Induced by Pressure Overload in Mice | J Am Heart Assoc Feb 2015 | Lenti | TL320558 |
| TPP1 | A High-Content Screen Identifies TPP1 and Aurora B as Regulators of Axonal Mitochondrial Transport | Cell Rep 2019 | Lenti | TL711322 |
| TRAF4 | Ubiquitination of the DNA-damage checkpoint kinase CHK1 by TRAF4 is required for CHK1 activation | J Hematol Oncol 2020 | Lenti | RC200345L4 |
| TREX1 | Accumulation of cytoplasmic DNA due to ATM deficiency activates the microglial viral response system with neurotoxic consequences | J. Neurosci. 2019 | Lenti | TL511298 |
| TRIM3 | Potential role of TRIM3 as a novel tumour suppressor in colorectal cancer (CRC) development | Scand. J. Gastroenterol. Dec 2015 | Lenti | RC211739L1 |
| TRIM32 | Trim32 suppresses cerebellar development and tumorigenesis by degrading Gli1/sonic hedgehog signaling | Cell Death Differ. 2019 | Lenti | RC201289L2 |
| TRIM32 | Trim32 suppresses cerebellar development and tumorigenesis by degrading Gli1/sonic hedgehog signaling | Cell Death Differ. 2019 | Lenti | TL308646 |
| TRIM33 | Hepatic stellate cell-specific knockout of transcriptional intermediary factor 1γ aggravates liver fibrosis | J. Exp. Med. 2020 | Lenti | TL300849 |
| TRIM8 | Transcription factor POU3F2 regulates TRIM8 expression contributing to cellular functions implicated in schizophrenia | Mol. Psychiatry 2020 | Lenti | TL300821V |
| TRIM8 | TRIM8 regulates stemness in glioblastoma through PIAS3-STAT3 | Mol Oncol 2017 | Lenti | RC205812L2 |
| TRIML2 | Eutherian-specific gene TRIML2 attenuates inflammation in the evolution of placentation | Mol. Biol. Evol. 2019 | Lenti | RC211281L1 |
| TRIP10 | Paxillin facilitates timely neurite initiation on soft-substrate environments by interacting with the endocytic machinery | Elife 2017 | Lenti | RC201200L1 |
| TRIT1 | Gene Amplification-Associated Overexpression of the Selenoprotein tRNA Enzyme TRIT1 Confers Sensitivity to Arsenic Trioxide in Small-Cell Lung Cancer | Cancers 2021 | Lenti | TL300819 |
| TRP53 | Trp53 and Rb1 regulate autophagy and ligand-dependent Hedgehog signaling | J. Clin. Invest. 2020 | Lenti | MR206086L4 |
| TRPM2 | Transient receptor potential ion channel TRPM2 promotes AML proliferation and survival through modulation of mitochondrial function, ROS, and autophagy | Cell Death Dis 2020 | Lenti | TL308624 |
| TRPM7 | Isoproterenol-Dependent Activation of TRPM7 Protects Against Neurotoxin-Induced Loss of Neuroblastoma Cells | Front Physiol 2020 | Lenti | TL320704 |
| TRPM7 | TGFβ-induced epithelial-to-mesenchymal transition in prostate cancer cells is mediated via TRPM7 expression | Mol. Carcinog. 2018 | Lenti | TL320704 |
| Trps1 | Transcription Factor Trps1 Promotes Tubular Cell Proliferation after Ischemia-Reperfusion Injury through cAMP-Specific 3',5'-Cyclic Phosphodiesterase 4D and AKT | J. Am. Soc. Nephrol 2017 | Lenti | TL708847 |
| TRPV1 | Capsaicin-induced Ca2+ Signaling is Enhanced via Upregulated TRPV1 Channels in Pulmonary Artery Smooth Muscle Cells from Patients with Idiopathic PAH | Am. J. Physiol. Lung Cell Mol. Physiol 2016 | Lenti | TL300807 |
| TRPV5 | Transient receptor potential vanilloid 5 (TRPV5), a highly Ca(2+) -selective TRP channel in the rat brain: relevance to neuroendocrine regulation | J. Neuroendocrinol 2017 | Lenti | RR208885L4 |
| TRPV6 | Transient receptor potential vanilloid 5 (TRPV5), a highly Ca(2+) -selective TRP channel in the rat brain: relevance to neuroendocrine regulation | J. Neuroendocrinol 2017 | Lenti | MR210315L4 |
| TUBB3 | Cathelicidin Suppresses Colon Cancer Metastasis via a P2RX7-Dependent Mechanism | Molecular Therapy - Oncolytics 2019 | Lenti | RC200755L1V |
| Twist1 | Vaccine-Mediated Immunotherapy Directed Against a Transcription Factor Driving the Metastatic Process | Cancer Res., Feb 2014. | Lenti | TL308556 |
| TXNIP | Loss of TXNIP enhances peritoneal metastasis and can be abrogated by dual TORC1/2 inhibition | Oncotarget 2018 | Lenti | TL308550 |
| TXNRD1 | Thioredoxin system as a gatekeeper in caspase-6 activation and nuclear lamina integrity: Implications for Alzheimer's disease | Free Radic. Biol. Med. 2019 | Lenti | TL300712 |
| TYRO3 | Oncogenic role of TYRO3 receptor tyrosine kinase in the progression of pancreatic cancer | Cancer Lett. 2019 | Lenti | TL316973 |
| UAP1 | Reciprocal Regulation Between O-GlcNAcylation and β-Catenin Facilitates Cell Viability and Inhibits Apoptosis in Liver Cancer | DNA Cell Biol. 2019 | Lenti | TL308538 |
| UBA2 | Allosteric Inhibition of Ubiquitin-like Modifications by a Class of Inhibitor of SUMO-Activating Enzyme | Cell Chem Biol 2019 | Lenti | RC201288L4 |
| UBE2N | The deubiquitinase OTUB1 augments NF-κB-dependent immune responses in dendritic cells in infection and inflammation by stabilizing UBC13 | Cell. Mol. Immunol. 2020 | Lenti | MR201092L1 |
| Ubqln1 | Enhanced Proteostasis in Post-ischemic Stroke Mouse Brains by Ubiquilin-1 Promotes Functional Recovery | Cell. Mol. Neurobiol 2016 | Lenti | TL515928 |
| UHRF1 | UHRF1 promotes human osteosarcoma cell invasion by downregulating the expression of E-cadherin in an Rb1-dependent manner | Mol Med Rep Nov 2015 | Lenti | RC214251L1 |
| USP26 | Targeting deubiquitinating enzyme USP26 by microRNA-203 regulates Snail1\'s pro-metastatic functions in esophageal cancer | Cancer Cell Int. 2020 | Lenti | RC223359L1V |
| USP7 | Integrative network analysis reveals USP7 haploinsufficiency inhibits E-protein activity in pediatric T-lineage acute lymphoblastic leukemia (T-ALL) | Scientific reports 2021 | Lenti | TL30845 |
| VAMP3 | Mouse genome-wide association studies and systems genetics uncover the genetic architecture associated with hepatic pharmacokinetic and pharmacodynamic properties of a constrained ethyl antisense oligonucleotide targeting Malat1 | PLoS Genet. 2018 | Lenti | TL515358V |
| VD | Hypovitaminosis D exacerbates the DNA damage load in human uterine fibroids, which is ameliorated by vitamin D3 treatment | Acta Pharmacol Sin 2018 | Lenti | TL320568 |
| VGLL3 | Intracellular Role for the Matrix-Modifying Enzyme Lox in Regulating Transcription Factor Subcellular Localization and Activity in Muscle Regeneration | Dev. Cell 2020 | Lenti | MR217588L1 |
| VHL | Ubiquitination of PPAR-gamma by pVHL inhibits ACLY expression and lipid metabolism, is implicated in tumor progression | Metab. Clin. Exp. 2020 | Lenti | TL300577 |
| VIM | The Group B Streptococcal surface antigen I/II protein, BspC, interacts with host vimentin to promote adherence to brain endothelium and inflammation during the pathogenesis of meningitis | PLoS Pathog. 2019 | Lenti | RC201546L1 |
| VPS35 | Stabilizing the Retromer Complex in a Human Stem Cell Model of Alzheimer’s Disease Reduces TAU Phosphorylation Independently of Amyloid Precursor Protein | Stem Cell Repor ts 2018 | Lenti | TL300553 |
| VRK2 | Deletion of the Vaccinia B1 Kinase Reveals Essential Functions of this Enzyme Complemented Partly by the Homologous Cellular Kinase VRK2 | J. Virol. 2017 | Lenti | RC206522L1 |
| WIF1 | Wnt Signaling Drives Prostate Cancer Bone Metastatic Tropism and Invasion | Transl Oncol 2020 | Lenti | RC205256L1 |
| WNK1 | WNK1-TAK1 signaling suppresses lipopolysaccharide-induced cytokine production and classical activation in macrophages | Biochem Biophys Res Commun 2020 | Lenti | TL506981 |
| WNT10A | Optimized dosing schedule based on circadian dynamics of mouse breast cancer stem cells improves the anti-tumor effects of aldehyde dehydrogenase | Cancer Res. 2018 | Lenti | TL502422 |
| WNT5A | Role of Wnt5a in suppressing invasiveness of hepatocellular carcinoma via epithelial-mesenchymal transition | Oncology letters 2020 | Lenti | TL320572 |
| WNT5A | Host Wnt5a Potentiates Microenvironmental Regulation of Ovarian Cancer Metastasis | Cancer Res. 2020 | Lenti | TL320572V |
| XRCC5 | Rad52 competes with Ku70/Ku86 for binding to S-region DSB ends to modulate antibody class-switch DNA recombination | Nat Commun 2017 | Lenti | TL502435 |
| XRN2 | XRN2 promotes EMT and metastasis through regulating maturation of miR-10a | Oncogene 2017 | Lenti | TL308334 |
| YAP | Corosolic acid inhibits cancer progress through inactivating YAP in hepatocellular carcinoma | Oncol. Res. 2020 | Lenti | RC225864L3 |
| YAP1 | Concurrent Targeting of Potential Cancer Stem Cells Regulating Pathways Sensitizes Lung Adenocarcinoma to Standard Chemotherapy | Mol. Cancer Ther. 2020 | Lenti | TL308332 |
| YAP1 | YAP inhibition enhances the differentiation of functional stem cell-derived insulin-producing β cells | Nat Commun 2019 | Lenti | TL308332 |
| Yap1 | YAP1 and COX2 coordinately regulate urothelial cancer stem-like cells | Cancer Res.2017 | Lenti | TL502437 |
| YWHAZ | Down-regulation of 14-3-3 zeta sensitizes human glioblastoma cells to apoptosis induction | Apoptosis 2018 | Lenti | TL308321V |
| ZBP1 | Mitochondrial DNA damage and subsequent activation of Z-DNA binding protein 1 links oxidative stress to inflammation in epithelial cells | Sci Rep 2018 | Lenti | TL300389 |
| ZBTB10 | The BTB Transcription Factors ZBTB11 and ZFP131 Maintain Pluripotency by Repressing Pro-Differentiation Genes | SSRN Electronic Journal 2021 | Lenti | MR214195L4 |
| ZBTB17 | Miz1, a Novel Target of ING4, Can Drive Prostate Luminal Epithelial Cell Differentiation | Prostate 2016 | Lenti | RC216143L1 |
| ZBTB7A | The miR-372-ZBTB7A Oncogenic Axis Suppresses TRAIL-R2 Associated Drug Sensitivity in Oral Carcinoma | Front Oncol 2020 | Lenti | RC222759L2 |
| ZDHHC15 | Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation | Research Square 2020 | Lenti | TL300350V |
| ZDHHC18 | DHHC protein family targets different subsets of glioma stem cells in specific niches | J. Exp. Clin. Cancer Res. 2019 | Lenti | RC209313L3 |
| ZDHHC23 | DHHC protein family targets different subsets of glioma stem cells in specific niches | J. Exp. Clin. Cancer Res. 2019 | Lenti | RC207272L3 |
| ZDHHC23 | DHHC protein family targets different subsets of glioma stem cells in specific niches | J. Exp. Clin. Cancer Res. 2019 | Lenti | TL300344 |
| ZDHHC8 | The palmitoyl acyltransferases ZDHHC5 and ZDHHC8 are uniquely present in DRG axons and control retrograde signaling via the Gp130/JAK/STAT3 pathway | J. Biol. Chem. 2020 | Lenti | TL703608 |
| ZEB1 | Zeb1-Hdac2-eNOS circuitry identifies early cardiovascular precursors in naive mouse embryonic stem cells | Nat Commun 2018 | Lenti | MR223095L2V |
| ZEB1 | Knockdown of ZEB1 suppressed the formation of vasculogenic mimicry and epithelial-mesenchymal transition in the human breast cancer cell line MDA-MB-231 | Mol Med Rep 2018 | Lenti | TL301174 |
| ZEB1 | MicroRNA-141 and MicroRNA-146b-5p Inhibit the pro-Metastatic Mesenchymal Characteristics through the RNA Binding Protein AUF1 Targeting the Transcription Factor ZEB1 and the Protein Kinase AKT | J. Biol. Chem. Sep 2014 | Lenti | TL301174 |
| ZEB2 | DEP-induced ZEB2 promotes nasal polyp formation via epithelial-to-mesenchymal transition | Journal of Allergy and Clinical Immunology 2021 | Lenti | TL308288 |
| ZEB2 | A pre-existing population of ZEB2+ quiescent cells with stemness and mesenchymal features dictate chemoresistance in colorectal cancer | J. Exp. Clin. Cancer Res. 2020 | Lenti | RC215227L2 |
| Zfp143 | The methyltransferase SETDB1 regulates a large neuron-specific topological chromatin domain | Nat. Genet. 2017 | Lenti | TL502149 |
| ZG16B | PAUF/ZG16B promotes colorectal cancer progression through alterations of the mitotic functions and the Wnt/β-catenin pathway | Carcinogenesis 2019 | Lenti | TL307561 |
| ZIC2 | ZIC2 is Essential for Maintenance of Latency and is a Target of an Immediate-Early Protein during KSHV Lytic Reactivation | J. Virol. 2017 | Lenti | RC220798L1 |
