CRISPR Citations

OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.

Search citations by gene symbols or target names

Here are some of the recent papers making use of OriGene products by fellow researchers.

Target Research Paper Journal Product SKU
An Efficient Targeted Mutagenesis System Using CRISPR/Cas in Monocotyledons Current Protocols in Plant Biology Jun 2016 CRISPR GE100007
ABCB1 Carbonic anhydrase XII inhibitors overcome P-glycoprotein-mediated resistance to temozolomide in glioblastoma Mol. Cancer Ther. 2018 CRISPR KN216080
ABCB5 Wnt/IL-1β/IL-8 autocrine circuitries control chemoresistance in mesothelioma initiating cells by inducing ABCB5 Int. J. Cancer 2019 CRISPR KN415604
ACVR1B Loss of ACVRIB leads to increased squamous cell carcinoma aggressiveness through alterations in cell-cell and cell-matrix adhesion proteins Am J Cancer Res 2017 CRISPR KN206920
ADAM8 Degradome of soluble ADAM10 and ADAM17 metalloproteases Cell. Mol. Life Sci. 2019 CRISPR KN213386
APC APC Inhibits Ligand-Independent Wnt Signaling by the Clathrin Endocytic Pathway Dev. Cell 2018 CRISPR KN211629
ARRB1 In vitro impact of FSH glycosylation variants on FSH receptor-stimulated signal transduction and functional selectivity Journal of the Endocrine Society 2020 CRISPR KN201279
ARRB2 In vitro impact of FSH glycosylation variants on FSH receptor-stimulated signal transduction and functional selectivity Journal of the Endocrine Society 2020 CRISPR KN201168
CA12 P-glycoprotein-mediated chemoresistance is reversed by carbonic anhydrase XII inhibitors Oncotarget 2016 CRISPR KN204034
CCR5 CCL5-CCR5 interactions modulate metabolic events during tumor onset to promote tumorigenesis BMC Cancer 2017 CRISPR KN216008
CD28 Trispecific antibodies enhance the therapeutic efficacy of tumor-directed T cells through T cell receptor co-stimulation Nat Cancer 2019 CRISPR KN211318
CRISPR The Krüppel-like factor 9 cistrome in mouse hippocampal neurons reveals predominant transcriptional repression via proximal promoter binding BMC Genomics 2017 CRISPR GE100018
CRISPR MICU1 Serves as a Molecular Gatekeeper to Prevent In Vivo Mitochondrial Calcium Overload Cell Rep 2016 CRISPR GE100025
CRISPR Product Genome editing in rice and wheat using the CRISPR/Cas system Nat Protoc Oct 2014 CRISPR GE100007
CRISPR vector YB-1 regulates tiRNA-induced Stress Granule formation but not translational repression Nucleic Acids Res., May 2016; 10.1093/nar/gkw418. CRISPR GE100002
CRISPR Vector G3BP–Caprin1–USP10 complexes mediate stress granule condensation and associate with 40S subunits J. Cell Biol., Mar 2016; 212: 845 - 860. CRISPR GE100001
CRISPR Vector Hypertension Causing Mutations in Cullin3 Impair RhoA Ubiquitination and Augment Association with Substrate Adaptors J. Biol. Chem. Jun 2015 CRISPR GE100018
CRISPR Vector Regulation of vascular function: roles for Cullin-3 and RhoBTB1 In Ppar?-mediated blood pressure control Thesis May 2015 CRISPR GE100018
CSDE1 Cold Shock Domain Containing E1 (CSDE1) Protein is Overexpressed and can be Targeted to Inhibit Invasiveness in Pancreatic Cancer Cells Proteomics 2020 CRISPR KN207101
CTSB Cathepsin B inhibition blocks neurite outgrowth in cultured neurons by regulating lysosomal trafficking and remodeling J. Neurochem. 2020 CRISPR KN303984
CXCL8 Wnt/IL-1β/IL-8 autocrine circuitries control chemoresistance in mesothelioma initiating cells by inducing ABCB5 Int. J. Cancer 2019 CRISPR KN202075
CYR61 Cyr61/CCN1 regulates dCK and CTGF and Causes Gemcitabine Resistant Phenotype in Pancreatic Ductal Adenocarcinoma Mol. Cancer Ther. 2019 CRISPR KN203492
DPH1 Disruption of diphthamide synthesis genes and resulting toxin resistance as a robust technology for quantifying and optimizing CRISPR/Cas9-mediated gene editing Sci Rep 2017 CRISPR KN221955
DPH2 Disruption of diphthamide synthesis genes and resulting toxin resistance as a robust technology for quantifying and optimizing CRISPR/Cas9-mediated gene editing Sci Rep 2017 CRISPR KN201382
DROSHA DROSHA-Dependent AIM2 Inflammasome Activation Contributes to Lung Inflammation during Idiopathic Pulmonary Fibrosis Cells 2019 CRISPR KN304817
FOXA2 Transcriptomic and CRISPR/Cas9 technologies reveal FOXA2 as a tumor suppressor gene in pancreatic cancer Am J Physiol Gastrointest Liver Physiol. 2016 CRISPR KN204066
FRS2 Pharmacologically targeting the myristoylation of the scaffold protein FRS2α inhibits FGF/FGFR-mediated oncogenic signaling and tumor progression J. Biol. Chem. 2018 CRISPR KN306139
GPD2 Metformin targets Mitochondrial Glycerophosphate Dehydrogenase (mGPDH) to control Rate of Oxidative Phosphorylation and growth of thyroid cancer in vitro and in vivo Clin. Cancer Res. 2018 CRISPR KN213341
HHAT Hedgehog Acyltransferase Promotes Uptake of Palmitoyl-CoA across the Endoplasmic Reticulum Membrane Cell Rep 2019 CRISPR KN208447
HTT ATP and spontaneous calcium oscillations control neural stem cell fate determination in Huntington\'s disease: a novel approach for cell clock research Mol. Psychiatry 2020 CRISPR KN308042
IL1B Wnt/IL-1β/IL-8 autocrine circuitries control chemoresistance in mesothelioma initiating cells by inducing ABCB5 Int. J. Cancer 2019 CRISPR KN402079
IL6 Targeting Interleukin-6 (IL-6) Sensitizes Anti-PD-L1 Treatment in a Colorectal Cancer Preclinical Model Med. Sci. Monit. 2018 CRISPR KN308293
KIF26B Genome-wide association and functional analyses identify CASC20 and KIF26B as target loci in heterotopic ossification BioRxiv 2019 CRISPR KN308785
MAMDC4 The Endosomal Protein Endotubin Is Required for Enterocyte Differentiation Cell Mol Gastroenterol Hepatol 2018 CRISPR KN216843
MGME1 Replication fork rescue in mammalian mitochondria Sci Rep 2019 CRISPR KN203886
NAT1 Loss of human arylamine N-acetyltransferase I regulates mitochondrial function by inhibition of the pyruvate dehydrogenase complex Int. J. Biochem. Cell Biol. 2019 CRISPR KN221042
NAT1 Arylamine N-acetyltransferase 1 protects against reactive oxygen species during glucose starvation: Role in the regulation of p53 stability PLoS ONE 2018 CRISPR KN221042
OGT O-GlcNAc modification of Sox2 regulates self-renewal in pancreatic cancer by promoting its stability Theranostics 2019 CRISPR KN206822
OGT O-GlcNAc modification of oncogenic transcription factor Sox2 promotes protein stability and regulates self-renewal in pancreatic cancer bioRxiv 2018 CRISPR KN206822
ORAI1 Genetic Manipulation of Calcium Release-Activated Calcium Channel 1 Modulates the Multipotency of Human Cartilage-Derived Mesenchymal Stem Cells Journal of Immunology Research 2019 CRISPR KN210034
pCas-Guide Proteomic Analysis of eIF5B Silencing-Modulated Proteostasis PLoS ONE 2016 CRISPR GE100002
pCas-Guide Cloning Mesenchymal Stem Cell Engineering Methods Mol. Biol. 2018 CRISPR GE100001
pCas-Guide Cloning Kit L1 retrotransposon antisense RNA within ASAR lncRNAs controls chromosome-wide replication timing J. Cell Biol. 2017 CRISPR GE100001
pCas-Guide-EF1a-GFP CTCF facilitates DNA double-strand break repair by enhancing homologous recombination repair Sci Adv 2017 CRISPR GE100018
pCas-Guide-GFP Eradication of Tumors through Simultaneous Ablation of CD276/B7-H3-Positive Tumor Cells and Tumor Vasculature Cancer Cell 2017 CRISPR GE100018
pCAS-Scramble A Safe Harbor-Targeted CRISPR/Cas9 Homology Independent Targeted Integration (HITI) System for Multi-Modality Reporter Gene-Based Cell Tracking bioRxiv 2020 CRISPR GE100003
pCAS-Scramble MAFG-driven astrocytes promote CNS inflammation Nature 2020 CRISPR GE100003
pCas-Scramble Temporal dynamics of protein complex formation and dissociation during human cytomegalovirus infection Nat Commun 2020 CRISPR GE100003
pCAS-Scramble Collagen IV (COL4A1, COL4A2), a Component of the Viral Biofilm, Is Induced by the HTLV-1 Oncoprotein Tax and Impacts Virus Transmission Front Microbiol 2019 CRISPR GE100003
PGP Insights into P-Glycoprotein Inhibitors: New Inducers of Immunogenic Cell Death Cells 2020 CRISPR KN414470
PLAUR The Urokinase Receptor Induces a Mesenchymal Gene Expression Signature in Glioblastoma Cells and Promotes Tumor Cell Survival in Neurospheres Sci Rep 2018 CRISPR KN201222
pLenti-Cas-Guide Impact of fatty acid binding protein 5-deficiency on COPD exacerbations and cigarette smoke-induced inflammatory response to bacterial infection Clin Transl Med 2019 CRISPR GE100010
PML PML plays both inimical and beneficial roles in HSV-1 replication Proc. Natl. Acad. Sci. U.S.A. May 2016 CRISPR KN200700
PPIA Coronaviruses and arteriviruses display striking differences in their cyclophilin A-dependence during replication in cell culture Virology 2017 CRISPR KN203307
PRNP Changes in cellular prion protein expression, Processing and localization during differentiation of the neuronal cell line CAD 5 Biol. Cell 2019 CRISPR KN313942
PTEN BRCA1-Associated Protein-1 Suppresses Osteosarcoma Cell Proliferation and Migration Through Regulation PI3K/Akt Pathway DNA Cell Biol 2017 CRISPR KN202627
PTGES The COX2 effector microsomal PGE2 synthase-1 is a regulator of immunosuppression in cutaneous melanoma Clin. Cancer Res. 2018 CRISPR KN314172
PTGS2 Knockdown of PTGS2 by CRISPR/CAS9 System Designates a New Potential Gene Target for Melanoma Treatment Front Pharmacol 2019 CRISPR KN314183
RHOB The critical role of dysregulated RhoB signaling pathway in radioresistance of colorectal cancer Int. J. Radiat. Oncol. Biol. Phys. 2019 CRISPR KN209837
SLC20A2 Vitamin-D receptor agonist calcitriol reduces calcification in vitro through selective upregulation of SLC20A2 but not SLC20A1 or XPR1 Sci Rep May 2016 CRISPR KN206029
SMURF2 SMURF2 prevents detrimental changes to chromatin, protecting human dermal fibroblasts from chromosomal instability and tumorigenesis Oncogene 2020 CRISPR KN210866
SMURF2 Generation of SMURF2 knockout human cells using the CRISPR/Cas9 system Anal. Biochem. 2017 CRISPR KN210866
STAG2 A requirement for STAG2 in replication fork progression creates a targetable synthetic lethality in cohesin-mutant cancers Nat Commun 2019 CRISPR KN400261
STAT3 Autologous reconstitution of human cancer and immune system in vivo Oncotarget 2017 CRISPR KN204922
STAT3 Integrin-FAK signaling rapidly and potently promotes mitochondrial function through STAT3 Cell Commun. Signal 2016 CRISPR KN316845
TFAM Mitochondrial DNA Copy Number (mtDNA-CN) Can Influence Mortality and Cardiovascular Disease via Methylation of Nuclear DNA CpGs bioRxiv 2019 CRISPR KN215488
TIFA Helicobacter pylori modulates host cell responses by CagT4SS-dependent translocation of an intermediate metabolite of LPS inner core heptose biosynthesis PLoS Pathog. 2017 CRISPR KN204357
TMX1 TMX1 determines cancer cell metabolism as a thiol-based modulator of ER-mitochondria Ca2+ flux J. Cell Biol. 2016 CRISPR KN206187
TNFRSF10B Targeting of dermal myofibroblasts through death receptor 5 arrests fibrosis in mouse models of scleroderma Nat Commun 2019 CRISPR KN517973
TP53 mir-660-p53-mir-486 Network: A New Key Regulatory Pathway in Lung Tumorigenesis Int J Mol Sci 2017 CRISPR KN200003
TRPM2 Depletion of the Human Ion Channel TRPM2 in Neuroblastoma Demonstrates its Key Role in Cell Survival through Modulation of Mitochondrial ROS and Bioenergetics J. Biol. Chem. 2016 CRISPR KN216220
UNC5B Repulsive Guidance Molecule a Inhibits Angiogenesis by Downregulating VEGF and Phosphorylated Focal Adhesion Kinase In Vitro Front Neurol 2017 CRISPR KN218267
VEGFA Cancer-derived small extracellular vesicles promote angiogenesis by heparin-bound, bevacizumab-insensitive VEGF, independent of vesicle uptake Commun Biol 2019 CRISPR KN217312