Protein Citations

OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.

Search citations by gene symbols or target names

Here are some of the recent papers making use of OriGene products by fellow researchers.

Target Research Paper Journal Product SKU
Coexposure to mercury increases immunotoxicity of trichloroethylene Toxicol. Sci. 2018 Protein AR03017PU-L
Coexposure to mercury increases immunotoxicity of trichloroethylene Toxicol. Sci. 2018 Protein AR03017PU-N
Coexposure to mercury increases immunotoxicity of trichloroethylene Toxicol. Sci. 2018 Protein AR03017PU-S
Adiponectin and its receptors are expressed in bone-forming cells Bone 2018 Protein PA502X
γ-Interferon-inducible lysosomal thiol reductase (GILT) maintains phagosomal proteolysis in alternatively activated macrophages J. Biol. Chem. 2018 Protein AR50577PU-N
γ-Interferon-inducible lysosomal thiol reductase (GILT) maintains phagosomal proteolysis in alternatively activated macrophages J. Biol. Chem. 2018 Protein AR50577PU-S
Adiponectin deficiency promotes endothelial activation and profoundly exacerbates sepsis-related mortality Am. J. Physiol. Endocrinol. Metab. 2018 Protein PA502X
Enabling low cost biopharmaceuticals: high level interferon alpha-2b production in Trichoderma reesei Microb. Cell Fact. 2018 Protein AR09043PU-L
Enabling low cost biopharmaceuticals: high level interferon alpha-2b production in Trichoderma reesei Microb. Cell Fact. 2018 Protein AR09043PU-N
Targeting the Hsp90 C-terminal domain to induce allosteric inhibition and selective client downregulation Biochim. Biophys. Acta 2017 Protein AR03017PU-L
Targeting the Hsp90 C-terminal domain to induce allosteric inhibition and selective client downregulation Biochim. Biophys. Acta 2017 Protein AR03017PU-N
Targeting the Hsp90 C-terminal domain to induce allosteric inhibition and selective client downregulation Biochim. Biophys. Acta 2017 Protein AR03017PU-S
Adiponectin modulates the glycogen synthase kinase-3beta/beta-catenin signaling pathway and attenuates mammary tumorigenesis of MDA-MB-231 cells in nude mice Cancer Res. 2016 Protein PA502X
Isolation of All CD44 Transcripts in Human Epidermis and Regulation of Their Expression by Various Agents PLoS ONE 2016 Protein BA1079
Oxidation and interaction of DJ-1 with 20S proteasome in the erythrocytes of early stage Parkinson's disease patients Sci Rep 2016 Protein AR03017PU-L
Oxidation and interaction of DJ-1 with 20S proteasome in the erythrocytes of early stage Parkinson's disease patients Sci Rep 2016 Protein AR03017PU-N
Oxidation and interaction of DJ-1 with 20S proteasome in the erythrocytes of early stage Parkinson's disease patients Sci Rep 2016 Protein AR03017PU-S
ARID4B is a good biomarker to predict tumour behaviour and decide WHO grades in gliomas and meningiomas J. Clin. Pathol. 2016 Protein LY500001
Experimental Anti-Inflammatory Drug Semapimod Inhibits TLR Signaling by Targeting the TLR Chaperone gp96 J. Immunol. 2016 Protein AR03017PU-L
Experimental Anti-Inflammatory Drug Semapimod Inhibits TLR Signaling by Targeting the TLR Chaperone gp96 J. Immunol. 2016 Protein AR03017PU-N
Experimental Anti-Inflammatory Drug Semapimod Inhibits TLR Signaling by Targeting the TLR Chaperone gp96 J. Immunol. 2016 Protein AR03017PU-S
Identification of novel aldose reductase inhibitors based on carboxymethylated mercaptotriazinoindole scaffold J. Med. Chem. 2016 Protein AR09195PU-L
Identification of novel aldose reductase inhibitors based on carboxymethylated mercaptotriazinoindole scaffold J. Med. Chem. 2016 Protein AR09195PU-N
Identification of new FGF1 binding partners-Implications for its intracellular function IUBMB Life 2016 Protein AR03017PU-L
Identification of new FGF1 binding partners-Implications for its intracellular function IUBMB Life 2016 Protein AR03017PU-N
Identification of new FGF1 binding partners-Implications for its intracellular function IUBMB Life 2016 Protein AR03017PU-S
Expanding the adipokine network in cartilage: identification and regulation of novel factors in human and murine chondrocytes Ann. Rheum. Dis. 2016 Protein PA502X
Tryptophan dendrimers that inhibit HIV replication, prevent virus entry and bind to the HIV envelope glycoproteins gp120 and gp41 Eur J Med Chem 2015 Protein BIN020
Molecular Interactions and Implications of Aldose Reductase Inhibition by PGA1 and Clinically Used Prostaglandins Mol. Pharmacol. 2015 Protein AR09146PU-L
Molecular Interactions and Implications of Aldose Reductase Inhibition by PGA1 and Clinically Used Prostaglandins Mol. Pharmacol. 2015 Protein AR09146PU-N
NICTABA and UDA, two GlcNAc-binding lectins with unique antiviral activity profiles J. Antimicrob. Chemother. 2015 Protein BIN020
Phosphorylation enhances recombinant HSP27 neuroprotection against focal cerebral ischemia in mice Neuroscience 2014 Protein SA6031
Phosphorylation enhances recombinant HSP27 neuroprotection against focal cerebral ischemia in mice Neuroscience 2014 Protein SA6031X
Adiponectin ameliorates dyslipidemia induced by the human immunodeficiency virus protease inhibitor ritonavir in mice Endocrinology 2013 Protein PA502X
Adiponectin attenuates allergen-induced airway inflammation and hyperresponsiveness in mice J. Allergy Clin. Immunol. 2012 Protein PA502X
Chaxamycins A-D, bioactive ansamycins from a hyper-arid desert Streptomyces sp J. Nat. Prod. 2011 Protein AR03017PU-L
Chaxamycins A-D, bioactive ansamycins from a hyper-arid desert Streptomyces sp J. Nat. Prod. 2011 Protein AR03017PU-N
Chaxamycins A-D, bioactive ansamycins from a hyper-arid desert Streptomyces sp J. Nat. Prod. 2011 Protein AR03017PU-S
Involvement of endothelial apoptosis underlying chronic obstructive pulmonary disease-like phenotype in adiponectin-null mice: implications for therapy Am. J. Respir. Crit. Care Med. 2011 Protein PA502X
Adiponectin deficiency increases allergic airway inflammation and pulmonary vascular remodeling Am. J. Respir. Cell Mol. Biol. 2009 Protein PA502X
Adiponectin inhibits cell proliferation by interacting with several growth factors in an oligomerization-dependent manner J. Biol. Chem. 2006 Protein PA502X
AADAC Influence of N-acetyltransferase 2 gene polymorphisms on the in vitro metabolism of the epidermal growth factor receptor inhibitor rociletinib British journal of clinical pharmacology 2021 Protein TP307111
ABI1 Abl interactor 1: A novel biomarker for osteoporosis in Chinese elderly men J Proteomics 2019 Protein TP317707
ABI1 An autism-linked missense mutation in SHANK3 reveals the modularity of Shank3 function Mol. Psychiatry 2019 Protein TP301264
ACO1 An Investigation of the Effect of MN2+ on the FTH1 IRE-IRP Complex Thesis May 2015 Protein TP301857
ACRBP Detection of sperm-reactive antibodies in wild sika deer and identification of the sperm antigens J. Vet. Med. Sci. 2018 Protein TP760494
ACTA2 Phosphoglycerate mutase 1 promotes cancer cell migration independent of its metabolic activity Oncogene 2016 Protein TP327802
ACTB The Huntingtin-interacting protein SETD2/HYPB is an actin lysine methyltransferase Sci Adv 2020 Protein TP303643
ACTB The Huntingtin-interacting protein SETD2/HYPB is an actin lysine methyltransferase Sci Adv 2020 Protein TP720518
ACTB SETD2 is an actin lysine methyltransferase bioRxiv 2020 Protein TP303643
ACTB SETD2 is an actin lysine methyltransferase bioRxiv 2020 Protein TP720518
ACTB Myeloid-Derived Lymphatic Endothelial Cell Progenitors Significantly Contribute to Lymphatic Metastasis in Clinical Breast Cancer Am. J. Pathol. 2019 Protein TP303643
ACTG1 Knockout of ACTB and ACTG1 with CRISPR/Cas9(D10A) Technique Shows that Non-Muscle β and γ Actin Are Not Equal in Relation to Human Melanoma Cells' Motility and Focal Adhesion Formation Int J Mol Sci 2020 Protein TP301730
ACTN4 Alpha-Actinin-4 is a Possible Target Protein for Aristolochic Acid I in Human Kidney Cells In Vitro Am. J. Chin. Med. Apr 2016 Protein TP302873
ADAR AKT-dependent phosphorylation of the adenosine deaminases ADAR-1 and -2 inhibits deaminase activity FASEB J. 2019 Protein TP319761
AGO2 An alternative microRNA-mediated post-transcriptional regulation of GADD45A by p53 in human non-small-cell lung cancer cells Sci Rep 2017 Protein TP328592
AGTR1 Dopamine D2 and angiotensin II type 1 receptors form functional heteromers in rat striatum Biochem. Pharmacol. May 2015 Protein LY429794
AGTR1 Critical period for dopaminergic neuroprotection by hormonal replacement in menopausal rats Neurobiol. Aging Nov 2014 Protein LY429794
AGTR2 Critical period for dopaminergic neuroprotection by hormonal replacement in menopausal rats Neurobiol. Aging Nov 2014 Protein LY400227
AKT1 Endogenous Cyclin D1 Promotes the Rate of Onset and Magnitude of Mitogenic Signaling via Akt1 Ser473 Phosphorylation Cell reports 2020 Protein TP320257
ALDH2 Mitochondrial ALDH2 protects against lipopolysaccharide-induced myocardial contractile dysfunction by suppression of ER stress and autophagy Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 2019 Protein TP300505
ALDOA Upregulation of the ALDOA/DNA-PK/p53 pathway by dietary restriction suppresses tumor growth Oncogene 2017 Protein TP720179
ALKBH1 N6-methyladenine DNA Modification in Glioblastoma Cell 2018 Protein TP306529
ALPI Multiplexed single-molecule enzyme activity analysis for counting disease-related proteins in biological samples Sci Adv 2020 Protein TP324178
ALPL Multiplexed single-molecule enzyme activity analysis for counting disease-related proteins in biological samples Sci Adv 2020 Protein TP305692
ALPPL2 ALPPL2 Is a Potential Diagnostic Biomarker for Pancreatic Cancer-Derived Extracellular Vesicles Molecular Therapy - Methods & Clinical Development 2019 Protein TP304330
ALT1 Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity Theranostics, Jan 2014. Protein TP303756
ALT2 Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity Theranostics, Jan 2014. Protein TP309119
AMACR Autoantibodies against oncogenic ERG protein in prostate cancer: potential use in diagnosis and prognosis in a panel with C-MYC, AMACR and HERV-K Gag Genes & Cancer 2016 Protein TP313437
AMBP Identification of a novel natriuretic protein in patients with cerebral-renal salt wasting - implications for enhanced diagnosis The American Journal of the Medical Sciences 2020 Protein TP308342
AMBRA1 Ambra1 spatially regulates Src activity and Src/FAK-mediated cancer cell invasion via trafficking networks Elife 2017 Protein TP306255
AMFR Affinity proteomics discovers decreased levels of AMFR in plasma from Osteoporosis patients Proteomics Clin Appl 2016 Protein LY420107
AMH Elevated prenatal anti-Müllerian hormone reprograms the fetus and induces polycystic ovary syndrome in adulthood Nat. Med. 2018 Protein TP308397
AMH Anti-mullerian hormone is expressed by endometriosis tissues and induces cell cycle arrest and apoptosis in endometriosis cells J. Exp. Clin. Cancer Res. Jun 2014 Protein TP308397
AMY1A Determination of Molar Mass and Its Relationship with Free Energy of Activation: A Case Study on Human Salivary Alpha Amylase Journal of Scientific Research & Reports 2016 Protein TP317403
ANAPC5 System Biology-Guided Chemical Proteomics to Discover Protein Targets of Monoethylhexyl Phthalate in Regulating Cell Cycle Environmental science & technology 2021 Protein TP303030
ANKRD1 Epitope-directed monoclonal antibody production using a mixed antigen cocktail facilitates antibody characterization and validation Communications biology 2021 Protein TP760289
ANXA2 Peripheral Blood Monocyte-expressed ANXA2 Gene is Involved in Pathogenesis of Osteoporosis in Humans Mol. Cell. Proteomics, Nov 2011; 10: M111.011700. Protein TP305081
ANXA6 Cytosolic dynamics of annexin A6 triggers feedback regulation of hypertrophy via atrial natriuretic peptide in cardiomyocytes J. Biol. Chem., Jan 2014. Protein LY400463
AOX1 In Vitro and In Silico Analyses of the Inhibition of Human Aldehyde Oxidase by Bazedoxifene, Lasofoxifene, and Structural Analogues J. Pharmacol. Exp. Ther. 2019 Protein TP319221
AOX1 Evaluation of Carbazeran 4-Oxidation and O6-Benzylguanine 8-Oxidation as Catalytic Markers of Human Aldehyde Oxidase: Impact of Cytosolic Contamination of Liver Microsomes Drug Metab. Dispos. 2018 Protein TP319221
APEX1 Inhibition of hydrogen sulfide biosynthesis sensitizes lung adenocarcinoma to chemotherapeutic drugs by inhibiting mitochondrial DNA repair and suppressing cellular bioenergetics Sci Rep 2016 Protein TP720082
APOA2 PI(4,5)P2 Is Translocated by ABCA1 to the Cell Surface Where It Mediates Apolipoprotein A1 Binding and Nascent HDL Assembly Circ. Res. 2016 Protein TP721104
APOBEC3A Apobec3A maintains HIV-1 latency through recruitment of epigenetic silencing machinery to the long terminal repeat Proc. Natl. Acad. Sci. U.S.A. 2019 Protein TP320995
APOBEC3G The double-domain cytidine deaminase APOBEC3G is a cellular site-specific RNA editing enzyme Sci Rep 2016 Protein LY411904
APOC2 Static and turnover kinetic measurement of protein biomarkers involved in triglyceride metabolism including apoB48 and apoA5 by LC-MS/MS J. Lipid Res. April 2014 Protein TP302771
APOC3 Apolipoprotein C-III in the high-density lipoprotein proteome of cerebral lacunar infarction patients impairs its anti-inflammatory function International Journal of Molecular Medicine 2017 Protein TP306566
APOC3 Static and turnover kinetic measurement of protein biomarkers involved in triglyceride metabolism including apoB48 and apoA5 by LC-MS/MS J. Lipid Res. April 2014 Protein TP306566
APOE The MT-CO1 V83I Polymorphism is a Risk Factor for Primary Open-Angle Glaucoma in African American Men Invest. Ophthalmol. Vis. Sci. 2018 Protein TP300395
APOE PI(4,5)P2 Is Translocated by ABCA1 to the Cell Surface Where It Mediates Apolipoprotein A1 Binding and Nascent HDL Assembly Circ. Res. 2016 Protein TP723016
APOE Static and turnover kinetic measurement of protein biomarkers involved in triglyceride metabolism including apoB48 and apoA5 by LC-MS/MS J. Lipid Res. April 2014 Protein TP300395
APP Chemoproteomic Profiling of Acetanilide Herbicides Reveals Their Role in Inhibiting Fatty Acid Oxidation ACS Chem. Biol 2017 Protein TP309575
APP Specific Amyloid ß Clearance by a Catalytic Antibody Construct J. Biol. Chem. Feb 2015 Protein TP309575
AQP3 Effects of Recombinant Aquaporin 3 and Seawater Acclimation on the Expression of Aquaporin 3 and 8 mRNAs in the Parr and Smolt Stages of Rainbow Trout, Oncorhynchus mykiss Ocean and Polar Research 2016 Protein TP301856
AQP3 Profiles of hypothalamus-pituitary-interrenal axis gene expression in the parr and smolt stages of rainbow trout, Oncorhynchus mykiss: Effects of recombinant aquaporin 3 and seawater acclimation Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. Dec 2014 Protein TP301856
AR Christmas disease in a Hovawart family resembling human hemophilia B Leyden is caused by a single nucleotide deletion in a highly conserved transcription factor binding site of the F9 gene promoter bioRxiv 2018 Protein TP761906
ARAF New level of regulation of MITF activity by direct interaction with RAF proteins Research Square 2021 Protein TP300737
ARPC2 Tumor-associated autoantibodies from mouse breast cancer models are found in serum of breast cancer patients npj Breast Cancer 2021 Protein TP300319
ARRB1 Methods to Determine Interaction Interfaces Between β-Arrestins and Their Protein Partners Methods Mol. Biol. 2019 Protein TP321737
ASAP1 Antibodies Directed against a Peptide Epitope of a Klebsiella pneumoniae-Derived Protein Are Present in Ankylosing Spondylitis PLoS ONE 2017 Protein LY413020
ASRGL1 Loss of ASRGL1 expression is an independent biomarker for disease-specific survival in endometrioid endometrial carcinoma Gynecol. Oncol. Apr 2015 Protein LY421255
ATF2 Novel Noncatalytic Substrate-Selective p38α-Specific MAPK Inhibitors with Endothelial-Stabilizing and Anti-Inflammatory Activity J. Immunol 2017 Protein TP710017
ATF3 Activating transcription factor 3 inhibits endometrial carcinoma aggressiveness via JunB suppression Int. J. Oncol. 2020 Protein TP760366
ATP1A1 The acaricidal mechanism and active compounds against Psoroptes cuniculi of the methanol extract of Adonis coerulea Maxim II: Integrated proteomics and SPR analysis Vet Parasitol 2020 Protein TP301009
ATP5A1 Tissue-specific expression and post-transcriptional regulation of the ATPase inhibitory factor 1 (IF1) in human and mouse tissues FASEB J. 2018 Protein TP314840
AVP Soluble ACE2-mediated cell entry of SARS-CoV-2 via interaction with proteins related to the renin-angiotensin system Cell 2021 Protein TP316816
AXIN1 Small-molecule binding of the axin RGS domain promotes ß-catenin and Ras degradation Nat. Chem. Biol. Jun 2016 Protein TP308349
BBC3 Using CETSA assay and a mathematical model to reveal dual Bcl-2/Mcl-1 inhibition and on-target mechanism for ABT-199 and S1 Eur J Pharm Sci 2019 Protein TP325345
BCCIP Efficient embryonic homozygous gene conversion via RAD51-enhanced interhomolog repair Cell 2021 Protein TP303061
BCKDK Phosphorylation of BCKDK of BCAA catabolism at Y246 by Src promotes metastasis of colorectal cancer Oncogene 2020 Protein TP303601
BCL2L1 Pan-Cancer Analysis Links PARK2 to BCL-XL-Dependent Control of Apoptosis Neoplasia 2016 Protein TP301314
BCL2L11 Using CETSA assay and a mathematical model to reveal dual Bcl-2/Mcl-1 inhibition and on-target mechanism for ABT-199 and S1 Eur J Pharm Sci 2019 Protein LY416580
BCL6 PRMT5 interacts with the BCL6 oncoprotein and is required for germinal center formation and lymphoma cell survival Blood 2018 Protein TP319007
BDNF U6 snRNA is a Suitable Endogenous Control for microRNA-124 and-134 in Cultured Rat Hippocampal Neurons Sains Malaysiana Jul 2015 Protein TP723035
BECN1 Cytosolic HMGB1 controls the cellular autophagy/apoptosis checkpoint during inflammation J. Clin. Invest. Mar 2015 Protein TP301629
Beta-catenin Phosphorylation of E-cadherin at threonine 790 by protein kinase Cd reduces ß-catenin binding and suppresses the function of E-cadherin Oncotarget 2016 Protein TP308947
BFGF Generation of periodontal ligament stem cells from human iPSCs with a chemically defined condition BIOLOGIA FUTURA 2020 Protein TP750002
BMI1 BMI1 regulates androgen receptor in prostate cancer independently of the polycomb repressive complex 1 Nat Commun 2018 Protein TP760041
BMI1 BMI1, a new target of CK2α Mol. Cancer 2017 Protein TP760041
BMP2 Overexpression of colorectal cancer oncogene CHRDL2 predicts a poor prognosis Oncotarget 2017 Protein TP750012
BPIFA1 Anti-BPIFA1/SPLUNC1: A new autoantibody prevalent in patients with endstage cystic fibrosis Journal of Cystic Fibrosis 23 October 2013 Protein TP313322
BRAF Newly Identified BRAF Mutation in Rheumatoid Arthritis Arthritis & rheumatology (Hoboken, N.J.) 2016 Protein TP700031
BTN3A2 Structural and functional diversity of metalloproteinases encoded by the Bacteroides fragilis pathogenicity island FEBS J. April 2014 Protein TP301183
BTN3A2 Butyrophilin 3A1 Plays an Essential Role in Prenyl Pyrophosphate Stimulation of Human V{gamma}2V{delta}2 T Cells J. Immunol., Aug 2013; 191: 1029 - 1042. Protein TP301183
C1QTNF6 C1q/TNF-Related Protein 6 Is a Pattern Recognition Molecule That Recruits Collectin-11 from the Complement System to Ligands J. Immunol. 2020 Protein TP304524
C21orf56 Antibody-based Protein Profiling of the Human Chromosome 21 Mol. Cell. Proteomics, Mar 2012; 11: M111.013458. Protein TP324562
C21orf59 Antibody-based Protein Profiling of the Human Chromosome 21 Mol. Cell. Proteomics, Mar 2012; 11: M111.013458. Protein TP300169
C4BPA Fucosylated C4b‑binding protein α‑chain, a novel serum biomarker that predicts lymph node metastasis in pancreatic ductal adenocarcinoma Oncology Letters 2020 Protein TP304738
C5AR1 Aptamers that bind to the human complement component receptor hC5aR1 interfere with hC5aR1 interaction to its hC5a ligand Mol. Biol. Rep. 2018 Protein TP303784
CA3 Cyclosporine A binding to COX-2 reveals a novel signaling pathway that activates the IRE1α unfolded protein response sensor Sci Rep 2018 Protein TP301066
CABS1 A method to study protein biomarkers in saliva using an automated capillary nano-immunoassay platform (Wes™) J. Immunol. Methods 2020 Protein LY409727
calgranulin B Antitumor effects of calgranulin B internalized in human colon cancer cells Oncotarget 2016 Protein TP308250
CALR A novel autoantibody targeting calreticulin is associated with cancer in patients with idiopathic inflammatory myopathies Clin Transl Immunology 2020 Protein TP303222
CALR Calnexin/Calreticulin and Assays Related to N-Glycoprotein Folding In Vitro Methods Mol. Biol. 2020 Protein TP303222
CALR Anti-Peptide Monoclonal Antibodies Generated for Immuno-Multiple Reaction Monitoring-Mass Spectrometry Assays Have a High Probability of Supporting Western blot and ELISA Mol. Cell Proteomics Feb 2015 Protein LY401384
CAMK2A Critical roles of Carbon Monoxide and Nitric Oxide in Ca2+ Signaling for Insulin Secretion in Pancreatic Islets Antioxid. Redox Signal. 2018 Protein TP318186
CAMK2G Ischemic heart injury leads to HIF1-dependent differential splicing of CaMK2γ Scientific reports 2021 Protein TP317059
CAPN1 Early to Intermediate Steps of Tumor Embolic Formation Involve Specific Proteolytic Processing of E-Cadherin Regulated by Rab7 Mol. Cancer Res., Jun 2012; 10: 713 - 726. Protein LY400662
CAPN2 Distinct Roles forµ-Calpain and m-Calpain in Synaptic NMDAR-Mediated Neuroprotection and Extrasynaptic NMDAR-Mediated Neurodegeneration J. Neurosci. 18880-92 Nov 2013 Protein TP305642
CAPN2 Calpain-2-Mediated PTEN Degradation Contributes to BDNF-Induced Stimulation of Dendritic Protein Synthesis J. Neurosci., Mar 2013; 33: 4317 - 4328. Protein TP305642
CAPN2 Early to Intermediate Steps of Tumor Embolic Formation Involve Specific Proteolytic Processing of E-Cadherin Regulated by Rab7 Mol. Cancer Res., Jun 2012; 10: 713 - 726. Protein TP305642
CAPRIN1 Stress Granules Regulate Double-Stranded RNA-Dependent Protein Kinase Activation through a Complex Containing G3BP1 and Caprin1 MBio Mar 2015 Protein TP300300
CAS9 Reciprocal monoallelic expression of ASAR lncRNA genes controls replication timing of human chromosome 6 bioRxiv 2019 Protein TP790148
CAV1 Deficiency of cold-inducible RNA-binding protein exacerbated monocrotaline-induced pulmonary artery hypertension through Caveolin1 and CAVIN1 Journal of cellular and molecular medicine 2021 Protein LY400664
CAVIN1 Deficiency of cold-inducible RNA-binding protein exacerbated monocrotaline-induced pulmonary artery hypertension through Caveolin1 and CAVIN1 Journal of cellular and molecular medicine 2021 Protein TP309277
CCL16 Gene expression of CCL8 and CXCL10 in peripheral blood leukocytes during early pregnancy in cows J Anim Sci Biotechnol 2018 Protein TP723266
CCL16 Possible Roles of CC- and CXC-Chemokines in Regulating Bovine Endometrial Function during Early Pregnancy Int J Mol Sci 2017 Protein TP723266
CCL5 Galectin-3 captures interferon-gamma in the tumor matrix reducing chemokine gradient production and T-cell tumor infiltration Nat Commun 2017 Protein TP303799
CCNY Cyclin Y, a novel actin-binding protein, regulates spine plasticity through the cofilin-actin pathway Prog. Neurobiol. 2020 Protein TP317807
CD274 The prognostic role of immune checkpoint markers programmed cell death protein 1 (PD-1) and programmed death ligand 1 (PD-L1) in a large, multicenter prostate cancer cohort oncotarget 2016 Protein LY415473
CD274 Assessing PD-L1 and PD-1 in Non-Small Cell Lung Cancer (NSCLC): a Novel Immunoscore Approach Clinical Lung Cancer 2016 Protein LY415473
CD33 Mono- and dual-targeting triplebodies activate natural killer cells and have anti-tumor activity in vitro and in vivo against chronic lymphocytic leukemia Oncoimmunology 2016 Protein TP307023
CD36 Fatty acid-induced CD36 expression via O-GlcNAcylation drives gastric cancer metastasis Theranostics 2019 Protein TP710013
CD44 A CD44 specific peptide developed by phage display for targeting gastric cancer Biotechnol. Lett. Jul 2015 Protein TP321771
CD44 Anti-Peptide Monoclonal Antibodies Generated for Immuno-Multiple Reaction Monitoring-Mass Spectrometry Assays Have a High Probability of Supporting Western blot and ELISA Mol. Cell Proteomics Feb 2015 Protein LY400203
CD55 Mutation of complement factor B causing massive fluid-phase dysregulation of the alternative complement pathway can result in atypical hemolytic uremic syndrome Kidney Int. 2020 Protein TP720284
CD70 Insights into the molecular basis of a bispecific antibody's target selectivity MAbs Mar 2015 Protein TP300410
CD81 Growth Hormone-Releasing Hormone Administration in Mild Cognitive Impairment and Its Impact on Neuronal Exosome Biomarkers of Dementia J. Alzheimers Dis. 2018 Protein TP317508
CD81 Exosomal biomarkers of brain insulin resistance associated with regional atrophy in Alzheimer's disease Hum Brain Mapp 2017 Protein TP317508
CD81 Decreased synaptic proteins in neuronal exosomes of frontotemporal dementia and Alzheimer's disease FASEB J.2016 Protein TP317508
CD81 Cargo proteins of plasma astrocyte-derived exosomes in Alzheimer's disease FASEB J. 2016 Protein TP317508
CD81 Prediction of conversion from mild cognitive impairment to dementia with neuronally derived blood exosome protein profile Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring May 2016 Protein TP317508
CD81 Dysfunctionally phosphorylated type 1 insulin receptor substrate in neural-derived blood exosomes of preclinical Alzheimer's disease FASEB J. Oct 2014 Protein TP317508
CD81 Identification of preclinical Alzheimer's disease by a profile of pathogenic proteins in neurally derived blood exosomes: A case-control study Alzheimers Dement Aug 2014 Protein TP317508
CD84 A 3 base pair deletion in TBX1 leads to reduced protein expression and transcriptional activity Sci Rep 2017 Protein LY9
CD9 Autoantibodies to tetraspanins (CD9, CD81 and CD82) in demyelinating diseases Journal of Neuroimmunology Feb 2016 Protein TP302000
CDCP1 Identification of anti-tumour biologics using primary tumour models, 3-D phenotypic screening and image-based multi-parametric profiling Mol. Cancer Aug 2015 Protein TP320633
CDH17 Anticipating metastasis through electrochemical immunosensing of tumor hypoxia biomarkers Analytical and bioanalytical chemistry 2021 Protein TP720740
CDH17 Magnetic beads-based electrochemical immunosensing of HIF-1α, a biomarker of tumoral hypoxia Sensors and Actuators B: Chemical 2020 Protein TP720740
CDH17 Dual Amperometric Immunosensor for Improving Cancer Metastasis Detection by the Simultaneous Determination of Extracellular and Soluble Circulating Fraction of Emerging Metastatic Biomarkers Electroanalysis 2019 Protein TP720740
CDH17 Disposable Amperometric Immunosensor for the Determination of the E-Cadherin Tumor Suppressor Protein in Cancer Cells and Human Tissues Electroanalysis 2018 Protein TP720740
CDH3 Identification of Putative Immunologic Targets for Colon Cancer Prevention Based on Conserved Gene Upregulation from Preinvasive to Malignant Lesions Cancer Prevention Research, Jul 2013; 6: 666 - 674. Protein TP307346
CDK2AP2 Proteome-wide epitope mapping of antibodies using ultra-dense peptide arrays Mol. Cell Proteomics. April 2014 Protein LY417039
CDKN1A Chemoproteomics-enabled discovery of covalent RNF114-based degraders that mimic natural product function Cell chemical biology 2021 Protein TP301765
CDKN1A Cyclin-dependent kinase 8 mediates chemotherapy-induced tumor-promoting paracrine activities PNAS, Aug 2012; 109: 13799 - 13804. Protein TP301765
CDT1 Distinct and sequential re-replication barriers ensure precise genome duplication bioRxiv 2020 Protein TP301657
CDT1 Cdt1 stabilizes kinetochore-microtubule attachments via an Aurora B kinase-dependent mechanism J. Cell Biol. 2018 Protein TP301657
CDT1 Human replication licensing factor Cdt1 directly links mitotic kinetochores to spindle microtubules bioRxiv 2017 Protein TP301657
CDYL Tubulin acetylation: A novel functional avenue for CDYL in sperm Cytoskeleton (Hoboken) 2017 Protein LY406868
CEBPA Arctigenin Inhibits Liver Cancer Tumorigenesis by Inhibiting Gankyrin Expression via C/EBPα and PPARα Front Pharmacol 2018 Protein TP760685
CENPA Autoantibody landscape of advanced prostate cancer biorxiv 2020 Protein TP324761
CFL2 Fatigue-Related Gene Networks Identified in CD14+ Cells Isolated From HIV-Infected Patients—Part I: Research Findings Biol Res Nurs, Apr 2013; 15: 137 - 151. Protein LY429663
CHERP RBM17 Interacts with U2SURP and CHERP to Regulate Expression and Splicing of RNA-Processing Proteins Cell Rep 2018 Protein TP761205
CHI3L1 Chitinase 3-like 1: prognostic biomarker in clinically isolated syndromes Brain Feb 2015 Protein TP303769
CHK2 The Viral SUMO-Targeted Ubiquitin Ligase ICP0 is Phosphorylated and Activated by Host Kinase Chk2 J. Mol. Biol. 2020 Protein TP301278
CHK2 The viral SUMO-targeted Ubiquitin Ligase ICP0 is phosphorylated and activated by host kinase Chk2 bioRxiv 2019 Protein TP301278
CHMP4B ADAPT identifies an ESCRT complex composition that discriminates VCaP from LNCaP prostate cancer cell exosomes Nucleic Acids Res. 2020 Protein TP307637
CHRDL2 Overexpression of colorectal cancer oncogene CHRDL2 predicts a poor prognosis Oncotarget 2017 Protein TP320245
CIRBP Extracellular CIRP Activates the IL-6Rα/STAT3/Cdk5 Pathway in Neurons Molecular neurobiology 2021 Protein TP301639
CIRBP Deficiency of cold-inducible RNA-binding protein exacerbated monocrotaline-induced pulmonary artery hypertension through Caveolin1 and CAVIN1 Journal of cellular and molecular medicine 2021 Protein TP301639
CIRBP Cold-inducible RNA-binding protein (CIRP) triggers inflammatory responses in hemorrhagic shock and sepsis J. Bacteriol., Aug 2013; 195: 3468 - 3475. Protein TP301639
CITED2 Aberrant expression of CITED2 promotes prostate cancer metastasis by activating the nucleolin-AKT pathway Nat Commun 2018 Protein TP329801
CLCN1 Abundance of ClC-1 chloride channel in human skeletal muscle: Fibre type specific differences and effect of training J. Appl. Physiol. 2018 Protein LY424940
CLEC4E Fungal engagement of the C-type lectin mincle suppresses dectin-1-induced antifungal immunity Cell Host Microbe 494-505 15 4. April 2014 Protein TP300244
CLIC2 Association of anti-CLIC2 and anti-HMGB1 autoantibodies with higher disease activity in systemic lupus erythematosus patients J Postgrad Med 2017 Protein TP304727
CLU PEGylated-Nanoliposomal Clusterin for Amyloidogenic Light Chain-Induced Endothelial Dysfunction J Liposome Res 2017 Protein TP311875
CLU Anti-Peptide Monoclonal Antibodies Generated for Immuno-Multiple Reaction Monitoring-Mass Spectrometry Assays Have a High Probability of Supporting Western blot and ELISA Mol. Cell Proteomics Feb 2015 Protein LY433124
CMPK1 Selective Phosphorylation of South and North-Cytidine and Adenosine Methanocarba-Nucleosides by Human Nucleoside and Nucleotide Kinases Correlates with Their Growth Inhibitory Effects on Cultured Cells Nucleosides Nucleotides Nucleic Acids Aug 2015 Protein TP304856
CMV Standard protocols for detection of human CMV-specific T cells Research Square 2021 Protein AR03041PU-N
CNN2 Calponin-h2: a potential serum marker for the early detection of human breast cancer? Tumour Biol. Aug 2014 Protein TP321104
CNP Schwann Cells Metabolize Extracellular 2',3'-cAMP to 2'-AMP J. Pharmacol. Exp. Ther. May 2015 Protein TP307038
COL7A1 Development of a Neo-Epitope Specific Assay for Serological Assessment of Type VII Collagen Turnover and Its Relevance in Fibroproliferative Disorders Assay Drug Dev Technol 2018 Protein LY424928
COL9A1 A SMOC2 variant inhibits BMP signaling by competitively binding to BMPR1B and causes growth plate defects Bone 2020 Protein TP318130
COL9A1 A variant in SMOC2, inhibiting BMP signaling by competitively binding to BMPR1B, causes multiple epiphyseal dysplasia BioRxiv 2020 Protein TP318130
COPS5 Berberine diminishes cancer cell PD-L1 expression and facilitates antitumor immunity via inhibiting the deubiquitination activity of CSN5 Acta Pharmaceutica Sinica B 2020 Protein TP300979
CORIN Sensitive and low-background electrochemical assay of corin activity via supramolecular recognition and rolling circle amplification Anal. Chim. Acta May 2016 Protein TP312742
COX20 Bioinformatic analysis of membrane and associated proteins in murine cardiomyocytes and human myocardium Scientific data 2020 Protein LY405090
CPAMD8 Morgagnian cataract resulting from a naturally occurring nonsense mutation elucidates a role of CPAMD8 in mammalian lens development PLoS ONE 2017 Protein LY414386
CPEB4 System Biology-Guided Chemical Proteomics to Discover Protein Targets of Monoethylhexyl Phthalate in Regulating Cell Cycle Environmental science & technology 2021 Protein TP321803
CPNE7 CPNE7 Induces Biological Dentin Sealing in a Dentin Hypersensitivity Model J. Dent. Res. 2019 Protein TP306428
CPNE7 The effect of CPNE7 on periodontal regeneration Connect. Tissue Res. 2019 Protein TP306428
CPNE7 Effect of preameloblast-conditioned medium and CPNE7 on root surfaces in dogs: a histologic and histomorphometric evaluation J. Mol. Histol. 2018 Protein TP306428
CPNE7 CPNE7, a preameloblast-derived factor, regulates odontoblastic differentiation of mesenchymal stem cells Biomaterials Oct 2014 Protein TP306428
CRABP2 Dissecting antibodies with regards to linear and conformational epitopes PLoS ONE Mar 2015 Protein LY419677
CREG1 CREG1 improves the capacity of the skeletal muscle response to exercise endurance via modulation of mitophagy Autophagy 2021 Protein TP750059
CREG1 Recombinant Cellular Repressor of E1A-Stimulated Genes Protects against Renal Fibrosis in Dahl Salt-Sensitive Rats Am. J. Nephrol. 2020 Protein TP301654
CRMP1 Autism-specific maternal autoantibodies recognize critical proteins in developing brain Translational Psychiatry 3, e277 doi:10.1038/tp.2013.50 Protein TP300483
CRMP2 Autism-specific maternal autoantibodies recognize critical proteins in developing brain Translational Psychiatry 3, e277 doi:10.1038/tp.2013.50 Protein LY419992
CRP Modified DNA Aptamers for C-Reactive Protein and Lactate Dehydrogenase-5 with Sub-Nanomolar Affinities Int J Mol Sci 2020 Protein TP317269
CRYBA1 βA1-crystallin regulates glucose metabolism and mitochondrial function in mouse retinal astrocytes by modulating PTP1B activity Communications biology 2021 Protein TP321965
CSF1 Extracellular calcium regulates the adhesion and migration of osteoclast via integrin αv β3 / Rho A/Cytoskeleton signaling Cell Biol. Int. 2018 Protein TP723290
CSNK1E Analysis of binding interfaces of the human scaffold protein AXIN1 by peptide microarrays J. Biol. Chem. 2018 Protein TP302436
CSRP1 Cross-reactivity of a pathogenic autoantibody to a tumor antigen in GABAA receptor encephalitis Proceedings of the National Academy of Sciences of the United States of America 2021 Protein TP307109
CSRP2 Cross-reactivity of a pathogenic autoantibody to a tumor antigen in GABAA receptor encephalitis Proceedings of the National Academy of Sciences of the United States of America 2021 Protein TP301565
CSRP3 Glomerular filtrate proteins in acute cardiorenal syndrome JCI Insight 2019 Protein TP325217
CSRP3 Aberrant Glycosylation in the Left Ventricle and Plasma of Rats with Cardiac Hypertrophy and Heart Failure PLoS ONE Jun 2016 Protein TP325217
CSTF2 RNA Binding Protein CELF2 Regulates Signal-Induced Alternative Polyadenylation by Competing with Enhancers of the Polyadenylation Machinery Cell Rep 2019 Protein TP304450
CTAG1B Autoantibody landscape of advanced prostate cancer biorxiv 2020 Protein TP313318
CTAG1B B cells in esophago-gastric adenocarcinoma are highly differentiated, organize in tertiary lymphoid structures and produce tumor-specific antibodies Oncoimmunology 2019 Protein TP313318
CTAG1B Case-Control Study: Smoking History Affects the Production of Tumor Antigen-Specific Antibodies NY-ESO-1 in Patients with Lung Cancer in Comparison with Cancer Disease-Free Group J Thorac Oncol 2016 Protein TP313318
CTAG1B Expression of tumor antigens on primary ovarian cancer cells compared to established ovarian cancer cell lines Oncotarget 2016 Protein TP313318
CTBP1 ZNF750 interacts with KLF4 and RCOR1, KDM1A, and CTBP1/2 chromatin regulators to repress epidermal progenitor genes and induce differentiation genes Genes Dev. Sep 2014 Protein TP310529
CTBP2 Phenformin Inhibits Hedgehog-Dependent Tumor Growth through a Complex I-Independent Redox/Corepressor Module Cell Rep 2020 Protein TP324861
CTBP2 ZNF750 interacts with KLF4 and RCOR1, KDM1A, and CTBP1/2 chromatin regulators to repress epidermal progenitor genes and induce differentiation genes Genes Dev. Sep 2014 Protein TP324861
CTCF Integration of human adipocyte chromosomal interactions with adipose gene expression prioritizes obesity-related genes from GWAS Nat Commun 2018 Protein TP720882
CTLA4 CTLA-4 expression in the non-small cell lung cancer patient tumor microenvironment: diverging prognostic impact in primary tumors and lymph node metastases Cancer Immunol. Immunother. 2017 Protein LY417438
CTTN Diagnostic utility of cortactin antibodies in myasthenia gravis Ann. N. Y. Acad. Sci.2017 Protein TP301111
CTTN Clinical Characteristics of Patients With Double-Seronegative Myasthenia Gravis and Antibodies to Cortactin JAMA Neurol 2016 Protein TP301111
CTTN Cortactin autoantibodies in myasthenia gravis Autoimmun Rev Sep 2014 Protein TP301111
CTTN Identification of a novel myositis-associated antibody directed against cortactin Autoimmunity Reviews Aug 2014 Protein TP301111
CXCL12 CXCR4 receptor blockage reduces the contribution of tumor and stromal cells to the metastatic growth in the liver Oncol. Rep. 2018 Protein TP307891
CYFRA 21-1 Label-free detection of tumor markers using field effect transistor (FET)-based biosensors for lung cancer diagnosis Sensors and Actuators B: Chemical 2015 Protein BA1026
CYLD CaMKII Mediates Recruitment and Activation of the Deubiquitinase CYLD at the Postsynaptic Density PLoS ONE Mar 2014 Protein TP304099
CYP19A1 Prognostic relevance of estrogen receptor a, ß and aromatase expression in non-small cell lung cancer Steroids May 2016 Protein LY400031
CYTL1 Salvianolic acid B regulates gene expression and promotes cell viability in chondrocytes J. Cell. Mol. Med 2017 Protein TP306778
DAXX PTEN regulates glioblastoma oncogenesis through chromatin-associated complexes of DAXX and histone H3.3 Nat Commun 2017 Protein TP326603
DBI Acyl-CoA-Binding Protein Is a Lipogenic Factor that Triggers Food Intake and Obesity Cell Metab. 2019 Protein TP308982
DCLK1 Alternative splice variants of DCLK1 mark cancer stem cells, promote self-renewal and drug-resistance, and can be targeted to inhibit tumorigenesis in kidney cancer Int. J. Cancer 2018 Protein TP331229
DCTN2 Early Cytoskeletal Protein Modifications Precede Overt Structural Degeneration in the DBA/2J Mouse Model of Glaucoma Front Neurosci 2016 Protein TP314771
DDR1 Selection of Antibodies with Tailored Properties by Application of High-Throughput Multiparameter Fluorescence-Activated Cell Sorting of Yeast-Displayed Immune Libraries Mol. Biotechnol. 2018 Protein TP710264
DDX1 A HIV-1 Tat mutant protein disrupts HIV-1 Rev function by targeting the DEAD-box RNA helicase DDX1 Retrovirology Dec 2014 Protein TP308769
DDX3X A HIV-1 Tat mutant protein disrupts HIV-1 Rev function by targeting the DEAD-box RNA helicase DDX1 Retrovirology Dec 2014 Protein TP304171
DDX5 DDX5-targeting fully human monoclonal autoantibody inhibits proliferation and promotes differentiation of acute promyelocytic leukemia cells by increasing ROS production Cell Death Dis 2020 Protein TP300371
DDX5 ATAD5 restricts R-loop formation through PCNA unloading and RNA helicase maintenance at the replication fork Nucleic Acids Res. 2020 Protein TP300371
DDX5 Resveratrol directly targets DDX5 resulting in suppression of the mTORC1 pathway in prostate cancer Cell Death Dis May 2016 Protein TP300371
DDX5 A Novel Anti-Cancer Agent, 1-(3, 5-Dimethoxyphenyl)-4-[(6-fluoro-2-methoxyquinoxalin-3-yl)aminocarbonyl] piperazine (RX-5902),Interferes with ß-Catenin Function through Y593 phospho-p68RNA Helicase J. Cell. Biochem. Feb 2015 Protein TP300371
DEFA5 Linking bacterial enterotoxins and alpha defensin 5 expansion in the Crohn\'s colitis: A new insight into the etiopathogenetic and differentiation triggers driving colonic inflammatory bowel disease PloS one 2021 Protein TP310219
DHODH Targeting Chikungunya Virus Replication by Benzoannulene Inhibitors Journal of medicinal chemistry 2021 Protein TP309034
DHODH Dihydroorotate dehydrogenase (DHODH) inhibitors affect ATP depletion, endogenous ROS and mediate S-phase arrest in breast cancer cells Biochimie 2017 Protein TP309034
DHODH Inhibition of Dihydroorotate Dehydrogenase Overcomes Differentiation Blockade in Acute Myeloid Leukemia Cell 2016 Protein TP309034
DHX36 RNA structure-wide discovery of functional interactions with multiplexed RNA motif library Nature communications 2020 Protein TP323929
DICER1 Labeling microRNA precursors for Dicer assays Anal. Biochem. 2019 Protein TP319214
DICER1 Structural basis of siRNA recognition by TRBP double-stranded RNA binding domains EMBO J. 2018 Protein TP319214
DICER1 Dicer interacts with SIRT7 and regulates H3K18 deacetylation in response to DNA damaging agents Nucleic Acids Res. Dec 2015 Protein TP319214
DIRAS3 CDK5 Regulates Paclitaxel Sensitivity in Ovarian Cancer Cells by Modulating AKT Activation, p21Cip1- and p27Kip1-Mediated G1 Cell Cycle Arrest and Apoptosis PLoS ONE Jul 2015 Protein TP302787
DISC1 Disrupted-in-Schizophrenia-1 Attenuates Amyloid-ß Generation and Cognitive Deficits in APP/PS1 Transgenic Mice by Reduction of ß-Site APP-Cleaving Enzyme 1 Levels Neuropsychopharmacology 2016 Protein TP312015
DKK1 Balanced Wnt/Dickkopf1 signaling by mesenchymal vascular progenitor cells in the microvascular niche maintains distal lung structure and function Am J Physiol Cell Physiol 2020 Protein TP723065
DKK1 Shared gene expression patterns in mesenchymal progenitors derived from lung and epidermis in pulmonary arterial hypertension: identifying key pathways in pulmonary vascular disease Pulm Circ 2016 Protein TP723065
DLAT Chemical Probes Reveal Sirt2\'s New Function as a Robust \"Eraser\" of Lysine Lipoylation J. Am. Chem. Soc. 2019 Protein TP306640
DLL3 Near infrared photoimmunotherapy targeting DLL3 for small cell lung cancer EBioMedicine 2020 Protein LY413792
DNM1L Protective Role of PGC-1a in Diabetic Nephropathy Is Associated with the Inhibition of ROS through Mitochondrial Dynamic Remodeling PLoS ONE Apr 2015 Protein TP321708
DNM2 A DNM2 Centronuclear Myopathy Mutation Reveals a Link between Recycling Endosome Scission and Autophagy Dev. Cell 2020 Protein TP323585
DNMT3A DNA G-quadruplexes show strong interaction with DNA methyltransferases in vitro FEBS Lett. 2016 Protein TP313064
DNMT3B DNA G-quadruplexes show strong interaction with DNA methyltransferases in vitro FEBS Lett. 2016 Protein TP323206
DNPEP A PAK5-DNPEP-USP4 axis dictates breast cancer growth and metastasis Int. J. Cancer 2019 Protein TP300104
DPYSL2 Increased levels of circulating GFAP and CRMP2 autoantibodies in the acute stage of spinal cord injury predict the subsequent development of neuropathic pain J. Neurotrauma 2018 Protein TP309080
DUPD1 H19 lncRNA Promotes Skeletal Muscle Insulin Sensitivity in Part by Targeting AMPK Diabetes 2018 Protein TP314361
E2F1 Recruitment of Pontin/Reptin by E2f1 amplifies E2f transcriptional response during cancer progression Nat Commun Dec 2015 Protein TP308247
E2F3 Recruitment of Pontin/Reptin by E2f1 amplifies E2f transcriptional response during cancer progression Nat Commun Dec 2015 Protein TP760363
EBI3 A novel IL-23p19/Ebi3 (IL-39) cytokine mediates inflammation in Lupus-like mice Eur. J. Immunol. Mar 2016 Protein TP723851
EEF1A1 HIV-1 Uncoating and Reverse Transcription Require eEF1A Binding to Surface-Exposed Acidic Residues of the Reverse Transcriptase Thumb Domain MBio 2018 Protein TP309697
EEF1A1 Specific Interaction between eEF1A and HIV RT Is Critical for HIV-1 Reverse Transcription and a Potential Anti-HIV Target PLoS Pathog. Dec 2015 Protein TP309697
EEF1A1 The Level of Autoantibodies Targeting Eukaryote Translation Elongation Factor 1 a1 and Ubiquitin-Conjugating Enzyme 2L3 in Nondiabetic Young Adults Diabetes Metab J Nov2015 Protein TP309697
EEF1A1 Identification of Novel Autoantibodies in Type 1 Diabetic Patients Using a High-Density Protein Microarray Diabetes Jun 2014 Protein TP309697
EEF1B2 Specific Interaction between eEF1A and HIV RT Is Critical for HIV-1 Reverse Transcription and a Potential Anti-HIV Target PLoS Pathog. Dec 2015 Protein TP321264
EEF1D Specific Interaction between eEF1A and HIV RT Is Critical for HIV-1 Reverse Transcription and a Potential Anti-HIV Target PLoS Pathog. Dec 2015 Protein TP303202
EEF1G Specific Interaction between eEF1A and HIV RT Is Critical for HIV-1 Reverse Transcription and a Potential Anti-HIV Target PLoS Pathog. Dec 2015 Protein TP319578
EFEMP1 Novel paracrine modulation of Notch-DLL4 signaling by fibulin-3 promotes angiogenesis in high-grade gliomas Cancer Res. Aug 2014 Protein TP314953
Eg5 APC/C is an essential regulator of centrosome clustering Nat Commun 3686 5 . April 2014 Protein TP318842
EGFL7 EGFL7 is expressed in bone microenvironment and promotes angiogenesis via ERK, STAT3, and integrin signaling cascades J. Cell. Physiol. Jun 2014 Protein TP723072
EGFP Gene Transfer in Adeno-Associated Virus Seropositive Rhesus Macaques Following Rapamycin Treatment and Subcutaneous Delivery of AAV6, but Not Retargeted AAV6 Vectors Hum Gene Ther 2020 Protein TP790050
EGFP Facile single-molecule pull-down assay for analysis of endogenous proteins Phys Biol 2019 Protein TP790050
EGFR Quantification of HER1, HER2 and HER3 by time-resolved Förster resonance energy transfer in FFPE triple-negative breast cancer samples British Journal of cancer 2019 Protein TP710011
EGFR Photoinduced Ligand Release from a Silicon Phthalocyanine Dye Conjugated with Monoclonal Antibodies: A Mechanism of Cancer Cell Cytotoxicity after Near-Infrared Photoimmunotherapy ACS Cent. Sci. 2018 Protein TP314877
EGFR Inhibition of triple-negative and Herceptin-resistant breast cancer cell proliferation and migration by Annexin A2 antibodies Br. J. Cancer Oct 2014 Protein TP710003
EGLN2 Proline Hydroxylation Primes Protein Kinases for Autophosphorylation and Activation Mol. Cell 2020 Protein TP306152
EGLN2 The LINK-A lncRNA activates normoxic HIF1 [alpha] signalling in triple-negative breast cancer Nature cell biology Jan 2016 Protein TP306152
EGLN3 The HIF-1α antisense long non-coding RNA drives a positive feedback loop of HIF-1α mediated transactivation and glycolysis Nature communications 2021 Protein TP310319
EGR1 Epigenetic Modulation of Radiation-Induced Diacylglycerol Kinase Alpha Expression Prevents Pro-Fibrotic Fibroblast Response Cancers 2021 Protein LY419625
EHD3 Insufficiency of ciliary cholesterol in hereditary Zellweger syndrome EMBO J. 2020 Protein TP761227
EIF2AK3 Human GRP78 affinity towards its signaling partners Ire1α and PERK is differently modulated by an unfolded protein client Biochem. Biophys. Res. Commun. 2017 Protein TP314993
EIF4A1 CELF1 is an EIF4E binding protein that promotes translation of epithelial-mesenchymal transition effector mRNAs bioRxiv 2019 Protein TP303298
EIF4G1 CELF1 is an EIF4E binding protein that promotes translation of epithelial-mesenchymal transition effector mRNAs bioRxiv 2019 Protein TP312877
EIF4G1 DAP5 associates with eIF2ß and eIF4AI to promote Internal Ribosome Entry Site driven translation Nucleic Acids Res. Mar 2015 Protein TP312877
ELAVL1 Ultra-fast conductive media for RNA electrophoretic mobility shift assays BioTechniques 2019 Protein TP301562
ELAVL1 Oncogenic p95HER2 regulates Na+-HCO3- cotransporter NBCn1 mRNA stability in breast cancer cells via 3'UTR dependent processes Biochem. J. 2016 Protein TP301562
ELAVL1 Tissue-specific control of brain-enriched miR-7 biogenesis Genes & Dev., Jan 2013; 27: 24 - 38. Protein TP301562
ELAVL4 The DPYSL2 gene connects mTOR and schizophrenia Transl Psychiatry 2016 Protein TP318612
ELF1 SDHD promoter mutations ablate GABP transcription factor binding in melanoma Cancer Res 2017 Protein TP760629
ELF1 An interaction proteomics survey of transcription factor binding at recurrent TERT promoter mutations Proteomics Nov 2015 Protein TP760629
EN2 Oncogenic Role of Secreted Engrailed Homeobox 2 (EN2) in Prostate Cancer J Clin Med 2019 Protein TP311220
ENGASE Repurposing of Proton Pump Inhibitors as first identified small molecule inhibitors of endo-β-N-acetylglucosaminidase (ENGase) for the treatment of NGLY1 deficiency, a rare genetic disease Bioorg. Med. Chem. Lett. 2017 Protein TP311494
ENPP2 Multiplexed single-molecule enzyme activity analysis for counting disease-related proteins in biological samples Sci Adv 2020 Protein LY421669
EP300 Aberrant expression of CITED2 promotes prostate cancer metastasis by activating the nucleolin-AKT pathway Nat Commun 2018 Protein TP710007
EP300 An Ultraconserved Brain-specific Enhancer within ADGRL3 (LPHN3) Underpins ADHD Susceptibility Biological Psychiatry 2016 Protein TP710007
EPRS Identification of a gamma interferon-activated inhibitor of translation-like RNA motif at the 3' end of the transmissible gastroenteritis coronavirus genome modulating innate immune response MBio Mar 2015 Protein TP317559
ERBB2 Dual-label time-resolved fluoroimmunoassay for simultaneous measurement of human epidermal growth factor receptor 2 and human epididymis protein 4 in serum J Anal Sci Technol 2020 Protein TP312583
ERBB2 Quantification of HER1, HER2 and HER3 by time-resolved Förster resonance energy transfer in FFPE triple-negative breast cancer samples British Journal of cancer 2019 Protein TP710032
ERBB2 Expression of tumor antigens on primary ovarian cancer cells compared to established ovarian cancer cell lines Oncotarget 2016 Protein TP312583
ERBB2 Anti-Peptide Monoclonal Antibodies Generated for Immuno-Multiple Reaction Monitoring-Mass Spectrometry Assays Have a High Probability of Supporting Western blot and ELISA Mol. Cell Proteomics Feb 2015 Protein LY417979
ERBB2 Anti-Peptide Monoclonal Antibodies Generated for Immuno-Multiple Reaction Monitoring-Mass Spectrometry Assays Have a High Probability of Supporting Western blot and ELISA Mol. Cell Proteomics Feb 2015 Protein LY423666
ERBB3 Quantification of HER1, HER2 and HER3 by time-resolved Förster resonance energy transfer in FFPE triple-negative breast cancer samples British Journal of cancer 2019 Protein TP710089
ERC1 Autophagy lipidation machinery regulates axonal microtubule dynamics but is dispensable for survival of mammalian neurons Nat Commun 2020 Protein TP313864
ERG Autoantibodies against oncogenic ERG protein in prostate cancer: potential use in diagnosis and prognosis in a panel with C-MYC, AMACR and HERV-K Gag Genes & Cancer 2016 Protein TP308093
ERG Analytical platform evaluation for quantification of ERG in prostate cancer using protein and mRNA detection methods Journal of Translational Medicine Jan 2015 Protein TP308093
ERN1 PRKCSH contributes to tumorigenesis by selective boosting of IRE1 signaling pathway Nat Commun 2019 Protein TP315023
ERN1 Human GRP78 affinity towards its signaling partners Ire1α and PERK is differently modulated by an unfolded protein client Biochem. Biophys. Res. Commun. 2017 Protein TP315023
ERN1 Hypothermia and Rewarming Activate a Macroglial Unfolded Protein Response Independent of Hypoxic-Ischemic Brain Injury in Neonatal Piglets Dev. Neurosci. 2016 Protein TP315023
ESR1 Butyl octyl phthalate interacts with estrogen receptor α in MCF‑7 breast cancer cells to promote cancer development World Academy of Sciences Journal 2021 Protein TP313277
ESR1 Bisphenolic compounds alter gene expression in MCF-7 cells through interaction with estrogen receptor α Toxicol. Appl. Pharmacol. 2020 Protein TP313277
ESR1 Indeno[1,2,3-cd]pyrene and picene mediate actions via estrogen receptor α signaling pathway in in vitro cell systems, altering gene expression Toxicol. Appl. Pharmacol. 2020 Protein TP313277
ESR1 Organophosphate ester tri-o-cresyl phosphate interacts with estrogen receptor α in MCF-7 breast cancer cells promoting cancer growth Toxicol. Appl. Pharmacol. 2020 Protein TP313277
ESR1 A Novel High Throughput Screening Assay for Binding Affinities of Perfluoroalkyl Iodide for Estrogen Receptor Alpha and Beta Isoforms Talanta 2017 Protein TP313277
ESR1 Prognostic relevance of estrogen receptor a, ß and aromatase expression in non-small cell lung cancer Steroids May 2016 Protein LY400046
ESR2 A Novel High Throughput Screening Assay for Binding Affinities of Perfluoroalkyl Iodide for Estrogen Receptor Alpha and Beta Isoforms Talanta 2017 Protein TP710031
ESR2 Prognostic relevance of estrogen receptor a, ß and aromatase expression in non-small cell lung cancer Steroids May 2016 Protein LY425704
ESRRG Antimitotic activity of DY131 and the estrogen-related receptor beta 2 (ERRβ2) splice variant in breast cancer Oncotarget 2016 Protein TP312143
ESRRG ERRß Splice Variants Differentially Regulate Cell Cycle Progression Cell Cycle Dec 2014 Protein TP312143
ETV7 ETV7 is an essential component of a rapamycin-insensitive mTOR complex in cancer Sci Adv 2018 Protein TP307742
EWSR1 Cohesin SA1 and SA2 are RNA binding proteins that localize to RNA containing regions on DNA Nucleic Acids Res. 2020 Protein TP303709
EWSR1 EWS-FLI1 increases transcription to cause R-loops and block BRCA1 repair in Ewing sarcoma Nature 2018 Protein TP303709
EWSR1 Liquid demixing of intrinsically disordered proteins is seeded by poly(ADP-ribose) Nat Commun Aug 2015 Protein TP303709
EZH2 SKP2 loss destabilizes EZH2 by promoting TRAF6-mediated ubiquitination to suppress prostate cancer Oncogene 2016 Protein TP302054
EZH2 Antisense RNA-Mediated Epigenetic Regulation of Brain-Derived Neurotrophic Factor Thesis Dec2015 Protein TP302054
EZH2 Screening for Small-Molecule Modulators of Long Noncoding RNA-Protein Interactions Using AlphaScreen J Biomol Screen Jul 2015 Protein TP302054
EZR A prospective study of autoantibodies to Ezrin and pancreatic cancer risk Cancer Causes Control Jun 2016 Protein TP300404
EZR Are ERM (ezrin/radixin/moesin) proteins targets for autoantibodies in demyelinating neuropathies? Hum. Immunol. Oct 2014 Protein TP300404
F2 Fully validated SRM-MS-based method for absolute quantification of PIVKA-II in human serum: Clinical applications for patients with HCC J Pharm Biomed Anal 2018 Protein TP308589
FAM162A Bioinformatic analysis of membrane and associated proteins in murine cardiomyocytes and human myocardium Scientific data 2020 Protein LY415331
FAM192A Time-Resolved Analysis Reveals Rapid Dynamics and Broad Scope of the CBP/p300 Acetylome Cell 2018 Protein TP304378
FAM3A The Stat3-Fam3a axis promotes muscle stem cell myogenic lineage progression by inducing mitochondrial respiration Nat Commun 2019 Protein TP303495
FAM46C FAM46C/TENT5C functions as a tumor suppressor through inhibition of Plk4 activity Commun Biol 2020 Protein TP315475
FAM84A Distinct oligoclonal band antibodies in multiple sclerosis recognize ubiquitous self-proteins Proc. Natl. Acad. Sci. U.S.A. Jun 2016 Protein TP308623
FBLN5 LTBP-2 competes with tropoelastin for binding to fibulin-5 and heparin, and is a negative modulator of elastinogenesis Matrix Biol. 2013 Oct 19. pii: S0945-053X(13)00136-4. doi: 10.1016 Protein TP304683
FBXO44 FBXO44 promotes DNA replication-coupled repetitive element silencing in cancer cells Cell 2020 Protein TP760409
FBXO48 A Fbxo48 inhibitor prevents pAMPKα degradation and ameliorates insulin resistance Nature chemical biology 2021 Protein TP760375
FCER1A Antibody to FceRIa Suppresses Immunoglobulin E Binding to High-Affinity Receptor I in Allergic Inflammation Yonsei Med. J. 2016 Protein LY400730
FCGRT Utility of a human FcRn transgenic mouse model in drug discovery for early assessment and prediction of human pharmacokinetics of monoclonal antibodies MAbs 2016 Protein TP300364
FCGRT Quantitative analysis of human neonatal Fc receptor (FcRn) tissue expression in transgenic mice by online peptide immuno-affinity LC-HRMS Anal. Chem. Mar 2016 Protein TP300364
FGF2 Identification of YAP1 as a novel downstream effector of the FGF2/STAT3 pathway in the pathogenesis of renal tubulointerstitial fibrosis Journal of cellular physiology 2021 Protein TP750002
FGF2 Interaction of Nerve Growth Factor β with Adiponectin and SPARC Oppositely Modulates its Biological Activity Int J Mol Sci 2019 Protein TP750002
FGF2 Single-Cell RNA-Seq Reveals Dynamic Early Embryonic-like Programs during Chemical Reprogramming Cell Stem Cell 2018 Protein TP750002
FGF2 Efficient derivation of extended pluripotent stem cells from NOD-scid Il2rg-/- mice Protein Cell 2018 Protein TP750002
FGF2 Genome-wide DNA methylation analysis reveals that mouse chemical iPSCs have closer epigenetic features to mESCs than OSKM-integrated iPSCs Cell Death Dis 2018 Protein TP750002
FGF2 Pluripotent stem cells induced from mouse neural stem cells and small intestinal epithelial cells by small molecule compounds Cell Res. Dec 2015 Protein TP750002
FGF2 Small-Molecule-Driven Direct Reprogramming of Mouse Fibroblasts into Functional Neurons Cell Stem Cell Aug 2015 Protein TP750002
FGF2 Pluripotent stem cells induced from mouse somatic cells by small-molecule compounds Science. 2013 Aug 9;341(6146):651-4. doi: 10.1126/science.1239278. Protein TP750002
FGF8 Haploinsufficiency of RREB1 causes a Noonan-like RASopathy via epigenetic reprogramming of RAS-MAPK pathway genes Nat Commun 2020 Protein TP723101
FHL1 Development of autoantibodies against muscle-specific FHL1 in severe inflammatory myopathies J. Clin. Invest. Nov 2015 Protein TP303478
FLNA S6K is a morphogenic protein with a mechanism involving Filamin-A phosphorylation and phosphatidic acid binding FASEB J. Dec 2014 Protein TP326488
FMOD Differentiated Cancer Cell-Derived Fibromodulin Promotes Angiogenesis and Tumor Growth Through Paracrine Signaling in Endothelial Cells SSRN Electronic Journal 2021 Protein LY419579
FMOD Melanocyte pigmentation inversely correlates with MCP-1 production and angiogenesis-inducing potential FASEB J. Nov 2014 Protein TP306534
FMR1 Fragile X mental retardation protein modulates the stability of its m6A-marked messenger RNA targets Human Molecular Genetics 2018 Protein TP322699
FOLR2 Growing Mouse Oocytes Transiently Activate Folate Transport via Folate Receptors As They Approach Full Size Biol. Reprod. Apr 2016 Protein LY400280
FOXM1 Reciprocal Regulation Between Forkhead Box M1/NF-kB and Methionine Adenosyltransferase 1A Drives Liver Cancer Hepatology 2020 Protein TP761576
FOXO1 Cellular hormetic response to 27-hydroxycholesterol promotes neuroprotection through AICD induction of MAST4 abundance and kinase activity Sci Rep 2017 Protein TP300477
FOXO3 Muscle Phenotype, Proteolysis, and Atrophy Signaling During Reloading in Mice: Effects of Curcumin on the Gastrocnemius Nutrients 2020 Protein LY400566
FOXO3 Histone deacetylase 3 associates with MeCP2 to regulate FOXO and social behavior Nat. Neurosci. 2016 Protein TP302894
FOXO3 FOXO3-NF-?B RelA Protein Complexes Reduce Proinflammatory Cell Signaling and Function J. Immunol. Nov 2015 Protein TP309846
FOXP1 Identification of a de novo FOXP1 mutation and incidental discovery of inherited genetic variants contributing to a case of autism spectrum disorder and epilepsy Mol Genet Genomic Med 2019 Protein LC403191
FOXP3 PD-1 Inhibitory Receptor Downregulates Asparaginyl Endopeptidase and Maintains Foxp3 Transcription Factor Stability in Induced Regulatory T Cells Immunity 2018 Protein TP317580
Foxp3 Functional characterization of Foxp3-specific spontaneous immune responses Leukemia doi:10.1038/leu.2013.196 Protein TP317580
FUBP1 FUBP1: a new protagonist in splicing regulation of the DMD gene Nucleic Acids Res. Feb 2015 Protein TP315674
FUS Molecular Dissection of FUS Points at Synergistic Effect of Low-Complexity Domains in Toxicity Cell Rep 2018 Protein TP301808
FUS EWS-FLI1 increases transcription to cause R-loops and block BRCA1 repair in Ewing sarcoma Nature 2018 Protein TP301808
FUS Comparative interactomics analysis of different ALS-associated proteins identifies converging molecular pathways Acta Neuropathol. May 2016 Protein TP301808
FUS Liquid demixing of intrinsically disordered proteins is seeded by poly(ADP-ribose) Nat Commun Aug 2015 Protein TP301808
FUS ALS-associated mutations in FUS disrupt the axonal distribution and function of SMN Hum. Mol. Genet., May 2013; 10.1093/hmg/ddt222. Protein TP301808
G0S2 G0/G1 Switch Gene 2 controls adipose triglyceride lipase activity and lipid metabolism in skeletal muscle Molecular Metabolism Apr 2016 Protein TP302063
G6PD Aspirin inhibits glucose-6-phosphate dehydrogenase activity in HCT 116 cells through acetylation: Identification of aspirin-acetylated sites Mol Med Rep 2016 Protein TP320625
GAPDH Cannabidiol and Oxygen-Ozone Combination Induce Cytotoxicity in Human Pancreatic Ductal Adenocarcinoma Cell Lines Cancers (Basel) 2020 Protein TA802519
GAPDH Anti-GAPDH Autoantibody Is Associated with Increased Disease Activity and Intracranial Pressure in Systemic Lupus Erythematosus J Immunol Res 2019 Protein TP302309
GATA3 Gata3-controlled nucleosome eviction drives Myc enhancer activity in T-cell development and leukemia Cancer Discov 2019 Protein TP301618
GATA3 Transactivation of human osteoprotegerin promoter by GATA-3 Sci Rep Jul 2015 Protein TP301618
GDF15 GDF-15 negatively regulates excess erythropoiesis and its overexpression is involved in erythroid hyperplasia Experimental Cell Research 2020 Protein TP790167
GDNF Identification of Patulin from Penicillium coprobium as a Toxin for Enteric Neurons Molecules 2019 Protein TP723138
Gemin5 The RNA-binding protein Gemin5 binds directly to the ribosome and regulates global translation Nucleic Acids Res. 2016 Protein TP317516
GFAP Increased levels of circulating GFAP and CRMP2 autoantibodies in the acute stage of spinal cord injury predict the subsequent development of neuropathic pain J. Neurotrauma 2018 Protein TP304548
GFPT2 Glutamine–Fructose-6-Phosphate Transaminase 1, 2 (GFPT1, 2) Handbook of Glycosyltransferases and Related Genes, Jan 2014. Protein LY417501
GLI1 Immunohistochemical visualization of the signature of activated Hedgehog signaling pathway in cutaneous epithelial tumors J. Dermatol. 2018 Protein TP301110
GLI1 Identification of a DYRK1A-mediated phosphorylation site within the nuclear localization sequence of the hedgehog transcription factor GLI1 Biochem. Biophys. Res. Commun. 2017 Protein TP301110
GMFB Substrate Specific Inhibitor Designed against the Immunomodulator GMF-beta Reversed the Experimental Autoimmune Encephalomyelitis Sci Rep 2020 Protein TP723145
GNAS ADCK2 Haploinsufficiency Reduces Mitochondrial Lipid Oxidation and Causes Myopathy Associated with CoQ Deficiency J Clin Med 2019 Protein TP314318
GNAS DHHC5 Mediates b-Adrenergic Signaling in Cardiomyocytes by Targeting Ga Proteins Biophysical Journal 2019 Protein TP314318
GNAS DHHC5 Mediates β-Adrenergic Signaling in Cardiomyocytes by Targeting Gα Proteins Biophys. J. 2019 Protein TP314318
GP2 Inflammatory Bowel Disease–associated GP2 Autoantibodies Inhibit Mucosal Immune Response to Adherent-invasive Bacteria Inflamm. Bowel Dis. 2020 Protein TP307512
GPLD1 Structure-function relationships of HDL in diabetes and coronary heart disease JCI Insight 2019 Protein TP317578
GPNMB The LINK-A lncRNA activates normoxic HIF1 [alpha] signalling in triple-negative breast cancer Nature cell biology Jan 2016 Protein TP307615
GPR4 Short-chain fatty acids and acidic pH up-regulate UT-B, GPR41, and GPR4 in rumen epithelial cells of goats Am. J. Physiol. Regul. Integr. Comp. Physiol. Dec 2014 Protein LY401625
GPR56 Proteome-wide epitope mapping of antibodies using ultra-dense peptide arrays Mol. Cell Proteomics. April 2014 Protein LY428998
GRB10 Antigen-specificity of antiretinal antibodies in patients with noninfectious uveitis Canadian Journal of Ophthalmology / Journal Canadien d'Ophtalmologie 2017 Protein TP306853
GREM1 ECM1 secreted by HER2-overexpressing breast cancer cells promotes formation of a vascular niche accelerating cancer cell migration and invasion Lab. Invest. 2020 Protein TP723147
GRIA1 Loss of Fragile X Protein FMRP Impairs Homeostatic Synaptic Downscaling through Tumor Suppressor p53 and Ubiquitin E3 Ligase Nedd4-2 Hum. Mol. Genet. 2018 Protein TP326253
GRIA1 Epilepsy-associated gene Nedd4-2 mediates neuronal activity and seizure susceptibility through AMPA receptors PLoS Genet 2017 Protein TP326253
GRINL1A Primary Central Nervous System (CNS) Lymphoma B Cell Receptors Recognize CNS Proteins J. Immunol. Aug 2015 Protein TP319621
GRN A Highly Sensitive Sandwich ELISA to Detect CSF Progranulin: A Potential Biomarker for CNS Disorders J. Neuropathol. Exp. Neurol. 2019 Protein TP302139
GSK3A Direct High Affinity Interaction between Aß42 and GSK3a Stimulates Hyperphosphorylation of Tau. A New Molecular Link in Alzheimer's Disease? ACS Chem Neurosci Dec 2015 Protein TP308698
GTSE1 A liquid-like spindle domain promotes acentrosomal spindle assembly in mammalian oocytes Science 2019 Protein TP761627
GZMK Antigen-specificity of antiretinal antibodies in patients with noninfectious uveitis Canadian Journal of Ophthalmology / Journal Canadien d'Ophtalmologie 2017 Protein LY419525
HADH Metabolomics and In Silico Docking-Directed Discovery of Small-Molecule Enzyme Targets Analytical chemistry 2021 Protein TP301752
HCAR2 4-Hydroxynonenal-induced GPR109A activation elicits bipolar responses, Gαi-mediated anti-inflammatory effects, and Gβγ-mediated cell death Br. J. Pharmacol. 2018 Protein TP306527
HDAC4 PARP1 Mediates LPS-Induced HMGB1 Release by Macrophages through Regulation of HMGB1 Acetylation J. Immunol. Nov 2014 Protein TP311495
HEK293 cell lysate LAG-3 in non-small cell lung cancer: expression in primary tumors and metastatic lymph nodes is associated with improved survival Clinical Lung Cancer 2017 Protein LY500001
HER-2/neu Case-Control Study: Smoking History Affects the Production of Tumor Antigen-Specific Antibodies NY-ESO-1 in Patients with Lung Cancer in Comparison with Cancer Disease-Free Group J Thorac Oncol 2016 Protein TP312583
HGF PAX2 promoted prostate cancer cell invasion through transcriptional regulation of HGF in an in vitro model Biochim. Biophys. Acta Aug 2015 Protein TP315593
HIC1 Variants in the fetal genome near pro-inflammatory cytokine genes on 2q13 associate with gestational duration Nat Commun 2019 Protein TP322752
HIC1 Variants in the fetal genome near pro-inflammatory cytokine genes on 2q13 are associated with gestational duration bioRxiv 2018 Protein TP322752
HLA-A Identifying Novel Drug Targets by iDTPnd: A Case Study of Kinase Inhibitors Genomics, proteomics & bioinformatics 2021 Protein TP300661
HLA-A Identifying Novel Targets by using Drug-binding Site Signature: A Case Study of Kinase Inhibitors bioRxiv 2019 Protein TP300661
HLA-B Identifying Novel Drug Targets by iDTPnd: A Case Study of Kinase Inhibitors Genomics, proteomics & bioinformatics 2021 Protein TP310631
HLA-B Identifying Novel Targets by using Drug-binding Site Signature: A Case Study of Kinase Inhibitors bioRxiv 2019 Protein TP310631
HLA-G Is there a role for HLA-G in the induction of regulatory T cells during the maintenance of a healthy pregnancy? Am. J. Reprod. Immunol. 2020 Protein TP305216
HLA-G Human Herpesvirus 6A and 6B inhibit in vitro angiogenesis by induction of Human Leukocyte Antigen G Sci Rep 2018 Protein TP305216
HLA-G1 Soluble factors derived from human amniotic epithelial cells suppress collagen production in human hepatic stellate cells Cytotherapy Mar 2014 Protein TP305216
HLAG Effects of everolimus and HLA-G on cellular proliferation and neutrophil adhesion in an in vitro model of cardiac allograft vasculopathy Am. J. Transplant. 2018 Protein TP305216
HMGB1 Association of anti-CLIC2 and anti-HMGB1 autoantibodies with higher disease activity in systemic lupus erythematosus patients J Postgrad Med 2017 Protein TP720309
HMGCR Anti-HMGCR Specificity of HALIP: A Confirmatory Study Journal of Immunology Research 2020 Protein TP762035
HNF4A Christmas disease in a Hovawart family resembling human hemophilia B Leyden is caused by a single nucleotide deletion in a highly conserved transcription factor binding site of the F9 gene promoter Haematologica 2019 Protein TP317863
HNF4A Sodium bicarbonate cotransporter NBCe2 gene variants increase sodium and bicarbonate transport in human renal proximal tubule cells PLoS ONE 2018 Protein TP317863
HNF4A Bile acids regulate cysteine catabolism and glutathione regeneration to modulate hepatic sensitivity to oxidative injury JCI Insight 2018 Protein TP316588
HNF4A Hepatocyte nuclear factor (HNF) 4a transactivation of cytochrome P450 (Cyp) 2d40 promoter is enhanced during pregnancy in mice Biochem. Pharmacol. Jan 2015 Protein TP317863
HNRNPA1 Identification of hnRNP-A1 as a pharmacodynamic biomarker of type I PRMT inhibition in blood and tumor tissues Scientific reports 2020 Protein TP303314
HNRNPA1 Blocking of an intronic splicing silencer completely rescues IKBKAP exon 20 splicing in familial dysautonomia patient cells Nucleic Acids Res. 2018 Protein TP303314
HNRNPA1 HNRNPA1 interacts with a 5'-flanking distal element of interleukin-6 and upregulates its basal transcription Genes and Immunity doi:10.1038/gene.2013.41 Protein TP303314
HNRNPA2B1 The cellular protein hnRNP A2/B1 enhances HIV-1 transcription by unfolding LTR promoter G-quadruplexes Sci Rep 2017 Protein TP319318
HNRNPC Alternatively Spliced ANLN Isoforms Synergistically Contribute To The Progression of Head and Neck Squamous Cell Carcinoma Research Square 2021 Protein TP315956
HNRNPK A dynamic i-motif with a duplex stem-loop in the long terminal repeat promoter of the HIV-1 proviral genome modulates viral transcription Nucleic Acids Res. 2019 Protein TP301843
HNRNPM Heterogeneous nuclear ribonucleoprotein M facilitates enterovirus infection J. Virol. Apr 2015 Protein TP760393
HNRNPU The RNA-binding protein hnRNPU regulates the sorting of microRNA-30c-5p into large extracellular vesicles Journal of Extracellular Vesicles 2020 Protein TP301627
HRAS A comprehensive screening method for investigating the potential binding targets of doxorubicin based on protein microarray European journal of pharmacology 2021 Protein TP316409
HRAS The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2 Mol. Cell 2019 Protein TP316409
HSD11B1 11Beta-Hydroxysteroid Dehydrogenase 1 Human Tissue Distribution, Selective Inhibitor and Role in Doxorubicin Metabolism Drug Metab. Dispos. 2018 Protein TP312093
HSD17B10 Metabolomics and In Silico Docking-Directed Discovery of Small-Molecule Enzyme Targets Analytical chemistry 2021 Protein TP301734
HSD17B13 Genome-wide association study of non-alcoholic fatty liver and steatohepatitis in a histologically-characterised cohort J. Hepatol. 2020 Protein TP313132
HSP90 The rapid and direct determination of ATPase activity by ion exchange chromatography and the application to the activity of heat shock protein-90 J Pharm Biomed Anal 2018 Protein AR03017PU-L
HSP90 The rapid and direct determination of ATPase activity by ion exchange chromatography and the application to the activity of heat shock protein-90 J Pharm Biomed Anal 2018 Protein AR03017PU-N
HSP90 The rapid and direct determination of ATPase activity by ion exchange chromatography and the application to the activity of heat shock protein-90 J Pharm Biomed Anal 2018 Protein AR03017PU-S
HSPA1A Warming enhances lanthanum accumulation and toxicity promoting cellular damage in glass eels (Anguilla anguilla) Environ. Res. 2020 Protein TP300270
HSPA1A Toxicity Evaluation of Quantum Dots (ZnS and CdS) Singly and Combined in Zebrafish (Danio rerio) IJERPH 2019 Protein TP300270
HSPA5 HSPA5 negatively regulates lysosomal activity through ubiquitination of MUL1 in head and neck cancer Autophagy 2017 Protein TP305859
HSPA5 Glucose-regulated protein 78 autoantibody associates with blood-brain barrier disruption in neuromyelitis optica Sci Transl Med 2017 Protein TP305859
HSPA5 Human GRP78 affinity towards its signaling partners Ire1α and PERK is differently modulated by an unfolded protein client Biochem. Biophys. Res. Commun. 2017 Protein TP305859
HSPA8 A micropeptide encoded by lncRNA MIR155HG suppresses autoimmune inflammation via modulating antigen presentation Sci. Adv. 2020 Protein TP302209
HSPH1 Extracellular HSP110 skews macrophage polarization in colorectal cancer OncoImmunology Apr 2016 Protein TP307102
HTRA1 N-Terminomics identifies HtrA1 cleavage of thrombospondin-1 with generation of a proangiogenic fragment in the polarized retinal pigment epithelial cell model of age-related macular degeneration Matrix Biol. 2018 Protein TP700208
HTRA1 N-Terminomics identifies HtrA1 cleavage of thrombospondin-1 with generation of a proangiogenic fragment in the polarized retinal pigment epithelial cell model of age-related macular degeneration Matrix Biol. 2018 Protein TP322362
HTRA1 HtrA1 Mediated Intracellular Effects on Tubulin Using a Polarized RPE Disease Model EBioMedicine 2017 Protein TP322362
HTRA1 HtrA1 Mediated Intracellular Effects on Tubulin Using a Polarized RPE Disease Model EBioMedicine 2017 Protein TP700208
ID3 PCB153-Induced Overexpression of ID3 Contributes to the Development of Microvascular Lesions PLoS ONE Aug 2014 Protein TP300583
IDE The core sequence of PIF competes for insulin/amyloid β in insulin degrading enzyme: potential treatment for Alzheimer's disease Oncotarget 2018 Protein TP320700
IDE Analysis of the proteolysis of bioactive peptides using a peptidomics approach Nature Protocols 8, 1730-1742 doi:10.1038/nprot.2013.104 Protein TP320700
IDH1 Antibody Validation for Western blot: By the User, for the User J. Biol. Chem. 2019 Protein TP310582
IDH1 Antibody Validation for Western blot: By the User, for the User J. Biol. Chem. 2019 Protein LY401782
IDH1 Antibody Validation for Western blot: By the User, for the User J. Biol. Chem. 2019 Protein LC810112
IDH1 A Highly Facile and Specific Assay for Cancer-Causing Isocitrate Dehydrogenase Mutant Using (13)C4-Labeled a-Ketoglutarate and Heteronuclear NMR Anal. Chem. Dec 2013. Protein TP310582
IDNK Fibrinolysis and proliferative endarteritis: two related processes in chronic infections? The model of the blood-borne pathogen Dirofilaria immitis PLoS ONE 2018 Protein BA522
IDO1 Synthesis, Docking and Biological Evaluation of a Novel Class of Imidazothiazoles as IDO1 Inhibitors Molecules 2019 Protein TP306592
IDUA Using the 2A Protein Coexpression System: Multicistronic 2A Vectors Expressing Gene(s) of Interest and Reporter Proteins Methods Mol. Biol. 2018 Protein TP319336
IFIH1 Neutrophil extracellular traps may contribute to interstitial lung disease associated with anti-MDA5 autoantibody positive dermatomyositis Clin. Rheumatol. 2017 Protein TP315661
IFIH1 Chemokine profiles of interstitial pneumonia in patients with dermatomyositis: a case control study Sci Rep 2017 Protein TP315661
IFIH1 Anti-MDA5 autoantibodies in juvenile dermatomyositis identify a distinct clinical phenotype: a prospective cohort study Arthritis Res. Ther. July 2014 Protein TP315661
IFNG High-Content Screening Differentiation and Maturation Analysis of Fetal and Adult Neural Stem Cell-Derived Oligodendrocyte Precursor Cell Cultures Journal of visualized experiments : JoVE 2021 Protein TP721239
IFNG CIITA-transduced glioblastoma cells uncover a rich repertoire of clinically relevant tumor-associated HLA-II antigens Molecular & cellular proteomics : MCP 2020 Protein TP723162
IFNG CIITA-related block of HLA class II expression, upregulation of HLA class I, and heterogeneous expression of immune checkpoints in hepatocarcinomas: implications for new therapeutic approaches Oncoimmunology 2019 Protein TP723162
IFNG Tripartite Motif-Containing Protein 22 Interacts with Class II Transactivator and Orchestrates Its Recruitment in Nuclear Bodies Containing TRIM19/PML and Cyclin T1 Front Immunol 2017 Protein TP721239
IFT57 BBSome function is required for both the morphogenesis and maintenance of the photoreceptor outer segment PLoS Genet. 2017 Protein LC402637
IGF1 Antagonistic Autoantibodies to Insulin-Like Growth Factor-1 Receptor Associate with Poor Physical Strength Int J Mol Sci 2020 Protein TP312527
IGF1R Non-peptidyl small molecule, adenosine, 5'-Se-methyl-5'-seleno-, 2',3'-diacetate, activates insulin receptor and attenuates hyperglycemia in type 2 diabetic Leprdb/db mice Cell. Mol. Life Sci. 2019 Protein TP314928
IGF2BP1 Dynamic expression of tRNA-derived small RNAs define cellular states EMBO Rep. 2019 Protein TP316226
IGF2BP1 Enhanced CLIP Uncovers IMP Protein-RNA Targets in Human Pluripotent Stem Cells Important for Cell Adhesion and Survival Cell Rep Apr 2016 Protein TP316226
IGFALS A draft map of the human ovarian proteome for tissue engineering and clinical applications Mol. Cell Proteomics 2018 Protein TP306542
IGFBP5 Apoptosis during embryonic tissue remodeling is accompanied by cell senescence Aging (Albany NY) Nov 2015 Protein TP723173
IgG2a Platelet Glycoprotein VI dependent Thrombus Stabilization is Essential for the Intraportal Engraftment of Pancreatic Islets Am J Transplant 2020 Protein SA021
IKBKB Development of novel NEMO-binding domain mimetics for inhibiting IKK/NF-κB activation PLoS Biol. 2018 Protein TP319154
IL16 IL-16/miR-125a axis controls neutrophil recruitment in pristane-induced lung inflammation JCI Insight 2018 Protein TP720036
IL17A High-Content Screening Differentiation and Maturation Analysis of Fetal and Adult Neural Stem Cell-Derived Oligodendrocyte Precursor Cell Cultures Journal of visualized experiments : JoVE 2021 Protein TP723199
IL17RD Orphan receptor IL-17RD regulates Toll-like receptor signalling via SEFIR/TIR interactions Nat Commun Mar 2015 Protein TP317198
IL1B High-Content Screening Differentiation and Maturation Analysis of Fetal and Adult Neural Stem Cell-Derived Oligodendrocyte Precursor Cell Cultures Journal of visualized experiments : JoVE 2021 Protein TP723210
IL1B Autoimmune inner ear disease patient–associated 28-kDa proinflammatory IL-1β fragment results from caspase-7–mediated cleavage in vitro JCI insight 2020 Protein TP302079
IL20 A systematic CRISPR screen reveals an IL-20/IL20RA-mediated immune crosstalk to prevent the ovarian cancer metastasis eLife 2021 Protein TP723795
IL23A Human neutrophils activated by TLR8 agonists, with or without IFNγ, synthesize and release EBI3, but not IL-12, IL-27, IL-35, or IL-39 J. Leukoc. Biol. 2020 Protein TP309680
IL23A Phage-assisted continuous evolution of proteases with altered substrate specificity Nat Commun 2017 Protein TP309680
IL23A A novel IL-23p19/Ebi3 (IL-39) cytokine mediates inflammation in Lupus-like mice Eur. J. Immunol. Mar 2016 Protein TP723221
IL6 High-Content Screening Differentiation and Maturation Analysis of Fetal and Adult Neural Stem Cell-Derived Oligodendrocyte Precursor Cell Cultures Journal of visualized experiments : JoVE 2021 Protein TP723240
IL6 Antibody Array Revealed PRL-3 Affects Protein Phosphorylation and Cytokine Secretion PLoS ONE 2017 Protein TP723240
IL9 Mogroside IIE Inhibits Digestive Enzymes via Suppression of Interleukin 9/Interleukin 9 Receptor Signalling in Acute Pancreatitis Front Pharmacol 2020 Protein TP723249
ILK Stabilization of integrin-linked kinase by the Hsp90-CHIP axis impacts cellular force generation, migration and the fibrotic response The EMBO Journal 32, 1409-1424 doi:10.1038/emboj.2013.90 Protein TP320460
INS High Glucose Accelerates Cell Proliferation and Increases the Secretion and mRNA Expression of Osteopontin in Human Pancreatic Duct Epithelial Cells Int J Mol Sci 2017 Protein TP302701
IPMK Identification of Small-Molecule Inhibitors of Human Inositol Hexakisphosphate Kinases by High-Throughput Screening ACS Pharmacology & Translational Science 2021 Protein TP309343
IPMK IPMK Mediates Activation of ULK Signaling and Transcriptional Regulation of Autophagy Linked to Liver Inflammation and Regeneration Cell Reports 2019 Protein TP309343
IREB2 Perturbation of Iron Metabolism by Cisplatin through Inhibition of Iron Regulatory Protein 2 Cell Chem Biol 2018 Protein TP321385
IRF5 Sex Differences in Plasmacytoid Dendritic Cell Levels of IRF5 Drive Higher IFN-a Production in Women J. Immunol. Dec 2015 Protein TP312461
IRF8 Affinity proteomic profiling of plasma, cerebrospinal fluid and brain tissue within multiple sclerosis J. Proteome Res. Sep 2014 Protein LY419485
ITGAL Mutually Exclusive Roles of SHARPIN in Integrin Inactivation and NF-?B Signaling PLoS ONE Nov 2015 Protein TP321297
ITGB2 Mycobacterium tuberculosis Mce3C promotes mycobacteria entry into macrophages through activation of β2 integrin-mediated signalling pathway Cell. Microbiol.2017 Protein TP326157
ITGB2 Mutually Exclusive Roles of SHARPIN in Integrin Inactivation and NF-?B Signaling PLoS ONE Nov 2015 Protein TP326157
JMJD6 JMJD6 regulates histone H2A.X phosphorylation and promotes autophagy in triple-negative breast cancer cells via a novel tyrosine kinase activity Oncogene 2018 Protein TP318163
JMJD6 Antibody-mediated blockade of JMJD6 interaction with collagen I exerts antifibrotic and antimetastatic activities The FASEB Journal 2017 Protein TP308993
JMJD6 Redistribution of demethylated RNA helicase A during foot-and-mouth disease virus infection: Role of Jumonji C-domain containing protein 6 in RHA demethylation Virology, 3 2014. Protein TP308993
JMJD6 Redistribution of demethylated RNA helicase A during foot-and-mouth disease virus infection: Role of Jumonji C-domain containing protein 6 in RHA demethylation Virology, 3 2014. Protein TP318163
JUNB Activating transcription factor 3 inhibits endometrial carcinoma aggressiveness via JunB suppression Int. J. Oncol. 2020 Protein TP303595
JUNB Time-Resolved Analysis Reveals Rapid Dynamics and Broad Scope of the CBP/p300 Acetylome Cell 2018 Protein TP303595
JUP PRDM14 directly interacts with heat shock proteins HSP90α and glucose-regulated protein 78 Cancer Sci. 2018 Protein TP304209
KAT3 Selective and competitive inhibition of kynurenine aminotransferase 2 by glycyrrhizic acid and its analogues Sci Rep 2019 Protein TP314155
KCNE5 The IKs Channel Response to cAMP Is Modulated by the KCNE1:KCNQ1 Stoichiometry Biophys. J. 2018 Protein TP306502
KCNK10 Up-Regulation of TREK-2 Potassium Channels in Cultured Astrocytes Requires De Novo Protein Synthesis: Relevance to Localization of TREK-2 Channels in Astrocytes after Transient Cerebral Ischemia PLoS ONE Apr 2015 Protein LY412052
KCNQ1 The IKs Channel Response to cAMP Is Modulated by the KCNE1:KCNQ1 Stoichiometry Biophys. J. 2018 Protein LY405589
KDM1A ZNF750 interacts with KLF4 and RCOR1, KDM1A, and CTBP1/2 chromatin regulators to repress epidermal progenitor genes and induce differentiation genes Genes Dev. Sep 2014 Protein TP330555
KEAP1 Seaweed natural products modify the host inflammatory response via Nrf2 signaling and alter colon microbiota composition and gene expression Free Radic. Biol. Med. 2019 Protein TP302189
KEAP1 Ginger Compound [6]-Shogaol and Its Cysteine-Conjugated Metabolite (M2) Activate Nrf2 in Colon Epithelial Cells in Vitro and in Vivo Chem. Res. Toxicol. Sep 2014 Protein TP302189
KEAP1 Identification of UV-protective Activators of Nuclear Factor Erythroid-derived 2-Related Factor 2 (Nrf2) by Combining a Chemical Library Screen with Computer-based Virtual Screening J. Biol. Chem., Sep 2012; 287: 33001 - 33013. Protein TP302189
KERA Immunolocalization of Keratan Sulfate in Rat Spinal Tissues Using the Keratanase Generated BKS-1(+) Neoepitope: Correlation of Expression Patterns with the Class II SLRPs, Lumican and Keratocan Cells 2020 Protein LY416127
KHDRBS1 Intronic tRNAs of mitochondrial origin regulate constitutive and alternative splicing Genome biology 2020 Protein TP300263
KIF11 HDAC Inhibitor-Induced Mitotic Arrest Is Mediated by Eg5/KIF11 Acetylation Cell Chem Biol 2017 Protein TP318842
KITL Prostaglandin E2, Produced by Mast Cells in Colon Tissues from Patients with Irritable Bowel Syndrome, Contributes to Visceral Hypersensitivity in Mice Gastroenterology 2020 Protein TP723398
KLF4 Pioneer transcription factors target partial DNA motifs on nucleosomes to initiate reprogramming Cell Apr 2015 Protein TP306691
KLF4 ZNF750 interacts with KLF4 and RCOR1, KDM1A, and CTBP1/2 chromatin regulators to repress epidermal progenitor genes and induce differentiation genes Genes Dev. Sep 2014 Protein TP306691
KMO Full-length in meso structure and mechanism of rat kynurenine 3-monooxygenase inhibition Communications biology 2021 Protein TP322594
KMO Development of a Surface Plasmon Resonance Assay for the Characterization of Small-Molecule Binding Kinetics and Mechanism of Binding to Kynurenine 3-Monooxygenase Assay Drug Dev Technol Aug 2015 Protein TP322594
KNG1 Identification of a novel natriuretic protein in patients with cerebral-renal salt wasting - implications for enhanced diagnosis The American Journal of the Medical Sciences 2020 Protein TP308879
KRAS The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2 Mol. Cell 2019 Protein TP700052
KRAS Selected reaction monitoring approach for validating peptide biomarkers Proc. Natl. Acad. Sci. U.S.A. 2017 Protein TP700052
KRT8 Tumor-associated autoantibodies from mouse breast cancer models are found in serum of breast cancer patients npj Breast Cancer 2021 Protein TP309570
KYAT1 A Novel Assay Method to Determine the β-Elimination of Se-Methylselenocysteine to Monomethylselenol by Kynurenine Aminotransferase 1 Antioxidants (Basel) 2020 Protein TP316317
LACC1 Functional Analyses of the Crohn's Disease Risk Gene LACC1 PLoS ONE 2016 Protein TP307834
LAG3 LAG-3 in non-small cell lung cancer: expression in primary tumors and metastatic lymph nodes is associated with improved survival Clinical Lung Cancer 2017 Protein LY400828
LAP3 Computational analysis of ligand dose range thermal proteome profiles bioRxiv 2020 Protein TP309052
LCP1 L-plastin S-glutathionylation promotes reduced binding to ß-actin and affects neutrophil functions Free Radic. Biol. Med. Apr 2015 Protein TP301670
LCP2 T cell receptor-dependent S-acylation of ZAP-70 controls activation of T cells bioRxiv 2020 Protein TP721201
LECT2 LECT2 induces atherosclerotic inflammatory reaction via CD209 receptor-mediated JNK phosphorylation in human endothelial cells Metab. Clin. Exp. Jun 2015 Protein TP310790
LGALS3 Targeting galectin-3 with a high-affinity antibody for inhibition of high-grade serous ovarian cancer and other MUC16/CA-125-expressing malignancies Scientific reports 2021 Protein TP308785
LIG1 Okazaki fragment maturation involves a-segment error editing by the mammalian FEN1/MutSa functional complex EMBO J. Apr 2015 Protein TP310760
LIPC Bioactive lysophospholipids generated by hepatic lipase degradation of lipoproteins lead to complement activation via the classical pathway Invest. Ophthalmol. Vis. Sci. Sep 2014 Protein TP315870
LIPG Blocking endothelial lipase with monoclonal antibody MEDI5884 durably increases high density lipoprotein in nonhuman primates and in a phase 1 trial Science translational medicine 2021 Protein TP309248
LMNB1 Nuclear matrix metalloproteinase-2 in the cardiomyocyte and the ischemic-reperfused heart J. Mol. Cell. Cardiol. Apr 2016 Protein TP301604
LMO4 Cisplatin-induced Ototoxicity Is Mediated by Nitroxidative Modification of Cochlear Proteins Characterized by Nitration of Lmo4 J. Biol. Chem., May 2012; 287: 18674 - 18686. Protein TP303914
LMOD1 Nodding syndrome may be an autoimmune reaction to the parasitic worm Onchocerca volvulus Sci Transl Med 2017 Protein TP309941
LOX Enzyme-Initiated Assembly of an Extracellular-Like Two-Dimensional Nanonetwork as a Method to Detect Procancerous Activity ACS sensors 2021 Protein TP313323
LOX Lysyl Oxidase Directly Contributes to Extracellular Matrix Production and Fibrosis in Systemic Sclerosis Am J Physiol Lung Cell Mol Physiol 2020 Protein TP313323
LOX Disrupted copper availability in sporadic ALS: Implications for CuII (atsm) as a treatment option BioRxiv 2020 Protein TP313323
LOX Blocking Surgically Induced Lysyl Oxidase Activity Reduces the Risk of Lung Metastases Cell Rep 2017 Protein TP313323
LOX Characterization of Microfibrillar-Associated Protein 4 (MFAP4) as a Tropoelastin- and Fibrillin-Binding Protein Involved in Elastic Fiber Formation J. Biol. Chem. Nov 2015 Protein TP313323
LOX The hypoxic cancer secretome induces pre-metastatic bone lesions through lysyl oxidase Nature Jun 2015 Protein TP313323
LOX Targeting the LOX/hypoxia axis reverses many of the features that make pancreatic cancer deadly: inhibition of LOX abrogates metastasis and enhances drug efficacy EMBO Mol Med Jun 2015 Protein TP313323
LOX Tissue Transglutaminase, Not Lysyl Oxidase, Dominates Early Calcium-Dependent Remodeling of Fibroblast-Populated Collagen Lattices Cells Tissues Organs (Print) Apr 2015 Protein TP313323
Lox Lysyl Oxidase Plays a Critical Role in Endothelial Cell Stimulation to Drive Tumor Angiogenesis Cancer Res., Jan 2013; 73: 583 - 594. Protein TP313323
LPLUNC1 LPLUNC1 Modulates Innate Immune Responses to Vibrio cholerae The Journal of Infectious Disease, Nov 2011; 204: 1349 - 1357. Protein TP303281
LTBP3 Cell-Type-Specific Gene Regulatory Networks Underlying Murine Neonatal Heart Regeneration at Single-Cell Resolution Cell reports 2020 Protein TP326379
LTC4S Maresin conjugates in tissue regeneration biosynthesis enzymes in human macrophages Proc. Natl. Acad. Sci. U.S.A. 2016 Protein TP306062
LUM Immunolocalization of Keratan Sulfate in Rat Spinal Tissues Using the Keratanase Generated BKS-1(+) Neoepitope: Correlation of Expression Patterns with the Class II SLRPs, Lumican and Keratocan Cells 2020 Protein AR51311PU-S
LUZP4 Leucine Zipper 4 Autoantibody: A Novel Germ Cell Tumor and Paraneoplastic Biomarker Annals of neurology 2021 Protein TP760382
LY500004 Matrix Metalloproteinase-19 Promotes Metastatic Behavior In Vitro and is Associated with Increased Mortality in Non-small Cell Lung Cancer Am. J. Respir. Crit. Care Med. Sep 2014 Protein LY500003
LY500005 Matrix Metalloproteinase-19 Promotes Metastatic Behavior In Vitro and is Associated with Increased Mortality in Non-small Cell Lung Cancer Am. J. Respir. Crit. Care Med. Sep 2014 Protein LY500004
LY500007 Matrix Metalloproteinase-19 Promotes Metastatic Behavior In Vitro and is Associated with Increased Mortality in Non-small Cell Lung Cancer Am. J. Respir. Crit. Care Med. Sep 2014 Protein LY500005
LY500009 Matrix Metalloproteinase-19 Promotes Metastatic Behavior In Vitro and is Associated with Increased Mortality in Non-small Cell Lung Cancer Am. J. Respir. Crit. Care Med. Sep 2014 Protein LY500007
LY96 Amniotic Fluid Soluble Myeloid Differentiation-2 (sMD-2) as Regulator of Intra-amniotic Inflammation in Infection-induced Preterm Birth Am. J. Reprod. Immunol. Jan 2015 Protein TP304686
LYAR Surface plasmon resonance based analysis of the binding of LYAR protein to the rs368698783 (G>A) polymorphic Aγ-globin gene sequences mutated in β-thalassemia Anal Bioanal Chem 2019 Protein LC428988
Lysates Development of a coordinated allo T-cell and auto B-cell response against autosomal PTK2B after allogeneic hematopoietic stem cell transplantation Haematologica. 2013 Oct 4 Protein
MACC1 Saffron Crudes and Compounds Restrict MACC1-Dependent Cell Proliferation and Migration of Colorectal Cancer Cells Cells 2020 Protein TP324774
MAGEA4 Case-Control Study: Smoking History Affects the Production of Tumor Antigen-Specific Antibodies NY-ESO-1 in Patients with Lung Cancer in Comparison with Cancer Disease-Free Group J Thorac Oncol 2016 Protein TP318952
MAGEA4 Expression of tumor antigens on primary ovarian cancer cells compared to established ovarian cancer cell lines Oncotarget 2016 Protein TP318952
MAP1LC3A Disrupted-in-schizophrenia-1 protects synaptic plasticity in a transgenic mouse model of Alzheimer's disease as a mitophagy receptor Aging Cell 2018 Protein TP760032
MAP2 Sex-Based Differences in Plasma Autoantibodies to Central Nervous System Proteins in Gulf War Veterans versus Healthy and Symptomatic Controls Brain sciences 2021 Protein TP316775
MAP2 Using Plasma Autoantibodies of Central Nervous System Proteins to Distinguish Veterans with Gulf War Illness from Healthy and Symptomatic Controls Brain sciences 2020 Protein TP316775
MAP2K6 The senescence-associated secretory phenotype is potentiated by feedforward regulatory mechanisms involving Zscan4 and TAK1 Nat Commun 2018 Protein TP304481
MAP3K1 Combating acquired resistance to MAPK inhibitors in melanoma by targeting Abl1/2-mediated reactivation of MEK/ERK/MYC signaling Nat Commun 2020 Protein TP314358
MAPKAP1 The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2 Mol. Cell 2019 Protein TP311745
MARCKS Identification of novel phosphatidic acid-binding proteins in the rat brain Neurosci. Lett. Apr 2015 Protein TP310277
MATR3 RNP-MaP: In-cell analysis of protein interaction networks defines functional hubs in RNA bioRxiv 2020 Protein TP323258
MATR3 Mutations in the Matrin 3 gene cause familial amyotrophic lateral sclerosis Nat. Neurosci. 664-6 17 5. May 2014 Protein TP323258
MAVS Zika virus antagonizes interferon response in patients and disrupts RIG-I-MAVS interaction through its CARD-TM domains Cell Biosci 2019 Protein TP308175
MAVS Dengue virus subverts host innate immunity by targeting adaptor protein MAVS J. Virol. Jun 2016 Protein TP308175
MAX Discovery of a Functional Covalent Ligand Targeting an Intrinsically Disordered Cysteine within MYC Cell chemical biology 2020 Protein TP306812
MBNL1 Muscleblind-like 1 activates insulin receptor exon 11 inclusion by enhancing U2AF65 binding and splicing of the upstream intron J. Cell Sci., Aug 2013; 126: 3782 - 3795. Protein TP323216
MCAM Characterization of novel neutralizing mouse monoclonal antibody JM1-24-3 developed against MUC18 in metastatic melanoma Journal of experimental & clinical cancer research : CR 2020 Protein TP308937
MCHERRY Gene Transfer in Adeno-Associated Virus Seropositive Rhesus Macaques Following Rapamycin Treatment and Subcutaneous Delivery of AAV6, but Not Retargeted AAV6 Vectors Hum Gene Ther 2020 Protein TP790040
MCHERRY mCherry Protein as an In Vivo Quantitative Reporter of Gene Expression in the Chloroplast of Chlamydomonas reinhardtii Mol. Biotechnol. 2020 Protein TP790040
MCHERRY Analysis of cytoplasmic and membrane molecular crowding in genetically programmed synthetic cells Biomacromolecules 2020 Protein TP790040
MCHERRY Stoichiometries of U2AF35, U2AF65 and U2 snRNP reveal new early spliceosome assembly pathways Nucleic Acids Res. 2016 Protein TP790040
MCM7 Replication stress induced by CCNE1 overexpression creates a dependency on XRCC2 at the replication fork bioRxiv 2018 Protein TP313809
MDA5 Increased Serum Matrix Metalloproteinase-9 Levels are Associated with Anti-Jo1 but not Anti-MDA5 in Myositis Patients Aging Dis 2019 Protein TP315661
MDA5 Anti-MDA5 Antibodies in a Large Mediterranean Population of Adults with Dermatomyositis Journal of Immunology Research, Feb 2014. Protein TP315661
MDK Intratumoural heterogeneity generated by Notch signalling promotes small-cell lung cancer Nature 2017 Protein TP723299
MDM2 Regulation of Cell Proliferation and Migration by miR-203 via GAS41/miR-10b Axis in Human Glioblastoma Cells PLoS ONE 2016 Protein LY400855
METRN Meteorin-like/Meteorin-β protects heart against cardiac dysfunction The Journal of experimental medicine 2021 Protein TP761464
MFN2 Obesity leads to impairments in the morphology and organization of human skeletal muscle lipid droplets and mitochondrial networks, which are resolved with gastric bypass surgery-induced improvements in insulin sensitivity Acta Physiol (Oxf) 2018 Protein TP302218
MFN2 Mfn2 Couples Glutamate Excitotoxicity and Mitochondrial Dysfunction in Motor Neurons J. Biol. Chem. Nov 2014 Protein TP326143
MGEA5 Thiamet-G-mediated inhibition of O-GlcNAcase sensitizes human leukemia cells to microtubule-stabilizing agent paclitaxel Biochem. Biophys. Res. Commun. Sep 2014 Protein TP322411
MIB1 A high-throughput genome-wide RNAi screen identifies modifiers of survival motor neuron protein Cell reports 2021 Protein TP321377
MIB1 ML372 blocks SMN ubiquitination and improves spinal muscular atrophy pathology in mice JCI Insight 2016 Protein TP321377
MIB1 The E3 ubiquitin ligase mind bomb 1 ubiquitinates and promotes the degradation of survival of motor neuron protein Mol. Biol. Cell, Jun 2013; 24: 1863 - 1871. Protein TP321377
MIIP MIIP?haploinsufficiency induces chromosomal instability and promotes tumour progression in colorectal cancer J. Pathol. 2016 Protein TP300779
MITF A Basic Domain-Derived Tripeptide Inhibits MITF Activity by Reducing its Binding to the Promoter of Target Genes The Journal of investigative dermatology 2021 Protein TP761494
MITF New level of regulation of MITF activity by direct interaction with RAF proteins Research Square 2021 Protein TP761396
MITF A signal transduction approach for multiplexed detection of transcription factors by integrating DNA nanotechnology, multi-channeled isothermal amplification, and chromatography Journal of Chromatography A 2020 Protein TP761396
MITF Detecting transcription factors with allosteric DNA-Silver nanocluster switches Anal. Chim. Acta 2019 Protein LY424990
MITF Detecting transcription factors with allosteric DNA-Silver nanocluster switches Analytica Chimica Acta 2018 Protein TP761396
MKNK2 Proteome-wide epitope mapping of antibodies using ultra-dense peptide arrays Mol. Cell Proteomics. April 2014 Protein LY413712
MORC3 Differential clinical associations of anti-nuclear matrix protein-2 autoantibodies in patients with idiopathic inflammatory myopathies Arthritis & rheumatology (Hoboken, N.J.) 2018 Protein TP310530
MORC3 Calcinosis in juvenile dermatomyositis is influenced by both anti-NXP2 autoantibody status and age at disease onset Rheumatology (Oxford) July 2014 Protein TP310530
MOV10 Mov10 suppresses retroelements and regulates neuronal development and function in the developing brain BMC Biol. 2017 Protein TP300934
MRE11 SPRTN protease-cleaved MRE11 decreases DNA repair and radiosensitises cancer cells Cell death & disease 2021 Protein TP761120
MRE11A UFL1 promotes histone H4 ufmylation and ATM activation Nat Commun 2019 Protein TP309414
MS4A8B Proteome-wide epitope mapping of antibodies using ultra-dense peptide arrays Mol. Cell Proteomics. April 2014 Protein LY403116
MSMP Induction of anti-VEGF therapy resistance by upregulated expression of microseminoprotein (MSMP) Oncogene 2017 Protein TP322527
MSN Are ERM (ezrin/radixin/moesin) proteins targets for autoantibodies in demyelinating neuropathies? Hum. Immunol. Oct 2014 Protein TP305674
MTDH Ezrin binds to DEAD-box RNA helicase DDX3 and regulates its function and protein level Mol. Cell. Biol. Jul 2015 Protein TP307238
MTF1 MTF1 binds to metal-responsive element e within the ATP7B promoter and is a strong candidate in regulating the ATP7B expression Ann. Hum. Genet. 2019 Protein TP304861
MTMR14 The small molecule AUTEN-99 (autophagy enhancer-99) prevents the progression of neurodegenerative symptoms Sci Rep 2017 Protein TP300809
MTMR14 AUTEN-67, an autophagy-enhancing drug candidate with potent antiaging and neuroprotective effects Autophagy Aug 2015 Protein TP300809
MTOR Tanc2-mediated mTOR inhibition balances mTORC1/2 signaling in the developing mouse brain and human neurons Nature communications 2021 Protein TP320457
MTOR Non-Thermal Plasma Induces Antileukemic Effect Through mTOR Ubiquitination Cells 2020 Protein TP320457
MTOR The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2 Mol. Cell 2019 Protein TP320457
MTOR mTOR kinase leads to PTEN-loss-induced cellular senescence by phosphorylating p53 Oncogene 2018 Protein TP320457
MTOR ETV7 is an essential component of a rapamycin-insensitive mTOR complex in cancer Sci Adv 2018 Protein TP320457
MTOR mTOR inhibition via displacement of phosphatidic acid induces enhanced cytotoxicity specifically in cancer cells Cancer Res. 2018 Protein TP320457
MTOR mTORC2 promotes type I insulin-like growth factor receptor and insulin receptor activation through the tyrosine kinase activity of mTOR Cell Res. Nov 2015 Protein TP320457
MUC1 Single‐Molecule Bioelectronic Label‐Free Assay of both Protein and Genomic Markers of Pancreatic Mucinous Cysts’ in Whole Blood Serum Advanced Electronic Materials 2021 Protein TP321390
MUC1 Enhanced binding of antibodies generated during chronic HIV infection to mucus component MUC16 Mucosal Immunol 2016 Protein TP321390
MUC1 Anti-Peptide Monoclonal Antibodies Generated for Immuno-Multiple Reaction Monitoring-Mass Spectrometry Assays Have a High Probability of Supporting Western blot and ELISA Mol. Cell Proteomics Feb 2015 Protein LY422694
MVP Proteomic analyses Identify Major Vault Protein as a Prognostic Biomarker for Fatal Prostate Cancer Carcinogenesis 2021 Protein LY413762
MYC Discovery of a Functional Covalent Ligand Targeting an Intrinsically Disordered Cysteine within MYC Cell chemical biology 2020 Protein TP301611
MYC Autoantibodies against oncogenic ERG protein in prostate cancer: potential use in diagnosis and prognosis in a panel with C-MYC, AMACR and HERV-K Gag Genes & Cancer 2016 Protein TP301611
MYC Pioneer transcription factors target partial DNA motifs on nucleosomes to initiate reprogramming Cell Apr 2015 Protein TP301611
MYC Reversible linkage of two distinct small molecule inhibitors of myc generates a dimeric inhibitor with improved potency that is active in myc over-expressing cancer cell lines PLoS ONE Apr 2015 Protein TP301611
MYC Sin3b Interacts with Myc and Decreases Myc Levels J. Biol. Chem. Jun 2014 Protein TP301611
MYOG Alternative utrophin mRNAs contribute to phenotypic differences between dystrophin-deficient mice and Duchenne muscular dystrophy FEBS Lett. 2018 Protein LY400882
NAA50 Chemoproteomic Profiling of Lysine Acetyltransferases Highlights an Expanded Landscape of Catalytic Acetylation J. Am. Chem. Soc. May 2014 Protein TP303388
NANS N-Acetylneuraminic Acid Synthase (NANS) Handbook of Glycosyltransferases and Related Genes, Feb 2014. Protein TP300123
NASP K-BILDS: A Kinase Substrate Discovery Tool Chembiochem 2016 Protein TP304052
NCF1 S-Glutathionylation of p47phox sustains superoxide generation in activated neutrophils Biochim. Biophys. Acta 2017 Protein TP301233
NCL Toward G-Quadruplex-Based Anticancer Agents: Biophysical and Biological Studies of Novel AS1411 Derivatives Int J Mol Sci 2020 Protein TP319082
NCL Specific suppression of D-RNA G-quadruplex-protein interaction with an L-RNA aptamer Nucleic Acids Res. 2020 Protein TP319082
NCL A novel nucleolin-binding peptide for Cancer Theranostics Theranostics 2020 Protein TP319082
NCL Aberrant expression of CITED2 promotes prostate cancer metastasis by activating the nucleolin-AKT pathway Nat Commun 2018 Protein TP319082
NCL Human CCDC47 sandwich immunoassay development with electrochemiluminescence technology J. Immunol. Methods 2017 Protein TP319082
NCL The cellular protein nucleolin preferentially binds long-looped G-quadruplex nucleic acids Biochim. Biophys. Acta 2016 Protein TP319082
NCL The G-quadruplex-forming aptamer AS1411 potently inhibits HIV-1 attachment to the host cell Int. J. Antimicrob. Agents Mar 2016 Protein TP319082
NCL Nucleolin promotes in vitro translation of feline calicivirus genomic RNA Virology Dec 2015 Protein TP319082
NCL Nucleolin stabilizes G-quadruplex structures folded by the LTR promoter and silences HIV-1 viral transcription Nucleic Acids Res. Sep 2015 Protein TP319082
NCOA7 The Ncoa7 locus regulates V-ATPase formation and function, neurodevelopment and behaviour Cellular and molecular life sciences : CMLS 2020 Protein TP321673
NEDD4L E3 ligase Nedd4l promotes antiviral innate immunity by catalyzing K29-linked cysteine ubiquitination of TRAF3 Nature communications 2021 Protein TP327866
NEFH Correlations between serum and CSF pNfH levels in ALS, FTD and controls: a comparison of three analytical approaches Clin. Chem. Lab. Med. 2019 Protein TP313487
NEFH Neurofilament changes in serum and cerebrospinal fluid after acute ischemic stroke Neurosci. Lett. 2018 Protein TP313487
Negative Ccontrol Transcriptomic profiling of cell-free and vesicular microRNAs from matched arterial and venous sera Journal of Extracellular Vesicles 2019 Protein LY500001
Negative Control Interactions of Antibodies to the Gram-Negative Gastric Bacterium Helicobacter pylori with the Synaptic Calcium Sensor Synaptotagmin 5, Correlate to Impaired Vesicle Recycling in SiMa Human Neuroblastoma Cells J. Mol. Neurosci. 2020 Protein LY500001
Negative Control A systematic approach to quantitative Western blot analysis Analytical Biochemistry 2020 Protein LY500001
Negative Control Antibody Validation for Western blot: By the User, for the User J. Biol. Chem. 2019 Protein LY500001
Negative Control Comparing small urinary extracellular vesicle purification methods with a view to RNA sequencing-Enabling robust and non-invasive biomarker research Biomol Detect Quantif 2019 Protein LY500001
Negative Control Highly specific monoclonal antibodies for allosteric inhibition and immunodetection of the human pancreatic zinc transporter ZnT8 J. Biol. Chem. 2018 Protein LY500001
Negative Control CTLA-4 expression in the non-small cell lung cancer patient tumor microenvironment: diverging prognostic impact in primary tumors and lymph node metastases Cancer Immunol. Immunother. 2017 Protein LY500001
Negative Control The prognostic role of immune checkpoint markers programmed cell death protein 1 (PD-1) and programmed death ligand 1 (PD-L1) in a large, multicenter prostate cancer cohort oncotarget 2016 Protein LY500001
negative control Assessing PD-L1 and PD-1 in Non-Small Cell Lung Cancer (NSCLC): a Novel Immunoscore Approach Clinical Lung Cancer 2016 Protein LY500001
NEO1 Hamster neogenin, a host-cell protein contained in a respiratory syncytial virus candidate vaccine, induces antibody responses in rabbits but not in clinical trial participants Hum Vaccin Immunother 2020 Protein TP316942
NEU1 Sialidase inhibitors attenuate pulmonary fibrosis in a mouse model Sci Rep 2017 Protein TP300386
NEU2 Sialidase inhibitors attenuate pulmonary fibrosis in a mouse model Sci Rep 2017 Protein TP319858
NEU3 Reduced Sialylation and Bioactivity of the Antifibrotic Protein Serum Amyloid P in the Sera of Patients with Idiopathic Pulmonary Fibrosis Immunohorizons 2020 Protein TP316537
NEU3 Sialidase inhibitors attenuate pulmonary fibrosis in a mouse model Sci Rep 2017 Protein TP316537
NEU4 Sialidase inhibitors attenuate pulmonary fibrosis in a mouse model Sci Rep 2017 Protein TP303948
NFE2L2 The Oncogenic Action of NRF2 Depends on De-glycation by Fructosamine-3-Kinase Cell 2019 Protein TP760529
NFKBIE A Map of Human Mitochondrial Protein Interactions Linked to Neurodegeneration Reveals New Mechanisms of Redox Homeostasis and NF-κB Signaling Cell Syst 2017 Protein TP760703
NFKBIE Annexin A4 and A6 induce membrane curvature and constriction during cell membrane repair Nat Commun 2017 Protein TP760703
NIT2 The Enzymology of 2-Hydroxyglutarate, 2-Hydroxyglutaramate and 2-Hydroxysuccinamate and Their Relationship to Oncometabolites Biology (Basel) 2017 Protein TP310660
NLGN3 Targeting neuronal activity-regulated neuroligin-3 dependency in high-grade glioma Nature 2017 Protein TP307955
NLGN3 Neuronal Activity Promotes Glioma Growth through Neuroligin-3 Secretion Cell Apr 2015 Protein TP307955
NLN Analysis of the proteolysis of bioactive peptides using a peptidomics approach Nature Protocols 8, 1730-1742 doi:10.1038/nprot.2013.104 Protein TP312447
NLRP10 Glial Uptake of Amyloid Beta Induces NLRP3 Inflammasome Formation via Cathepsin-Dependent Degradation of NLRP10 Neuromolecular Med. Nov 2013 Protein TP311215
NOL4 Cancer Testis Antigen, NOL4, Is an Immunogenic Antigen Specifically Expressed in Small-Cell Lung Cancer Current oncology (Toronto, Ont.) 2021 Protein TP322286
NONO IGFBP-3 interacts with NONO and SFPQ in PARP-dependent DNA damage repair in triple-negative breast cancer Cell. Mol. Life Sci. 2019 Protein TP326567
NOTUM A Strategy for Discovery of Endocrine Interactions with Application to Whole-Body Metabolism Cell Metab. 2018 Protein TP309331
NOXA1 CHIP ubiquitylates NOXA and induces its lysosomal degradation in response to DNA damage Cell death & disease 2020 Protein TP308357
NPM1 Time-Resolved Analysis Reveals Rapid Dynamics and Broad Scope of the CBP/p300 Acetylome Cell 2018 Protein TP303841
NPTX2 Neuronal Pentraxin 2 is a regulator of clear cell renal cell carcinoma malignancy through activation of the AMPA-selective glutamate receptor 4 Cancer Res. Jun 2014 Protein TP306713
NR1H2 Photoaffinity Labeling and Quantitative Chemical Proteomics Identify LXRβ as the Functional Target of Enhancers of Astrocytic apoE Cell Chem Biol 2020 Protein TP308381
NR1H2 Fungal-derived neoechinulin B as a novel antagonist of liver X receptor, identified by chemical genetics using hepatitis C virus cell culture system J. Virol. 2016 Protein TP308381
NR1H3 Insulin induction of SREBP-1c in rodent liver requires LXRa-C/EBPß complex Proc. Natl. Acad. Sci. U.S.A. 2016 Protein TP323767
NR4A1 Molecular, Chemical, and Structural Characterization of Prostaglandin A2 as a Novel Agonist for Nur77 Biochem. J. 2019 Protein TP302202
NRAS The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2 Mol. Cell 2019 Protein TP701004
NRAS The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2 Mol. Cell 2019 Protein TP302681
NRGN Derivation of a Three Biomarker Panel to Improve Diagnosis in Patients with Mild Traumatic Brain Injury Front Neurol 2017 Protein TP301209
NT5C1A Anti-cN-1A autoantibodies are absent in juvenile dermatomyositis Arthritis & rheumatology (Hoboken, N.J.) 2021 Protein TP324617
NT5C1A HLA-DRB1 allele and autoantibody profiles in Japanese patients with inclusion body myositis PLoS ONE 2020 Protein TP324617
NT5C1A Anti-NT5c1A Autoantibodies as Biomarkers in Inclusion Body Myositis Front Immunol 2019 Protein TP324617
NT5E Virtual Screening Approach for the Identification of Hydroxamic Acids as Novel Human Ecto-5\'-Nucleotidase Inhibitors J Chem Inf Model 2019 Protein TP720666
NUDT1 Addiction to MTH1 protein results in intense expression in human breast cancer tissue as measured by liquid chromatography-isotope-dilution tandem mass spectrometry DNA Repair Jun 2015 Protein LY419314
NUDT15 The existence of MTH1-independent 8-oxodGTPase activity in cancer cells as a compensatory mechanism against on-target effects of MTH1 inhibitors Mol. Cancer Ther. 2019 Protein TP310477
NXP2 Oral Abstracts 3: Adolescent and Young Adult • O13. Hypermobility is a Risk Factor for Musculoskeletal Pain in Adolescence: Findings From a Prospective Cohort Study Rheumatology, Apr 2013; 52: i33 - i43. Protein TP310530
OCRL A phosphoglycolate phosphatase/AUM-dependent link between triacylglycerol turnover and epidermal growth factor signaling Biochim. Biophys. Acta 2018 Protein TP320672
ODC1 A Label-Free Continuous Fluorescence-Based Assay for Monitoring Ornithine Decarboxylase Activity with a Synthetic Putrescine Receptor SLAS Discovery 2017 Protein TP306858
ODC1 Cystathionine-beta-synthase inhibition for colon cancer: Enhancement of the efficacy of aminooxyacetic acid via the prodrug approach Mol. Med. 2016 Protein TP306858
OGG1 Reactive oxygen species induced by icaritin promote DNA strand breaks and apoptosis in human cervical cancer cells Oncol. Rep. 2018 Protein TP720109
OGN Transforming Growth Factor-β3 Regulates Adipocyte Number in Subcutaneous White Adipose Tissue Cell Rep 2018 Protein TP323948
OLR1 The lipid moiety 7-ketocholesteryl-9-carboxynonanoate mediates binding interaction of oxLDL to LOX-1 and upregulates ABCA1 expression through PPARγ Life Sci. 2017 Protein TP304704
OSCP1 In vivo tunable CRISPR mediates efficient somatic mutagenesis to generate tumor models Protein Cell 2018 Protein TP318808
OSM Hyaluronic acid-alendronate conjugate: A macromolecular drug delivery system for intra-articular treatment of osteoarthritis Osteoarthritis and Cartilage Open 2021 Protein TP723340
OSM Amphiphilic peptide-based MMP3 inhibitors for intra-articular treatment of knee OA Bioorganic & Medicinal Chemistry 2021 Protein TP304277
OXR1 Oxidation resistance 1 regulates post-translational modifications of peroxiredoxin 2 in the cerebellum Free Radic. Biol. Med. 2018 Protein TP760961
OXR1 Oxidation resistance 1 is a novel senolytic target Aging Cell 2018 Protein TP760961
p65 TNF-a Induction of CXCL10 in Endothelial Cells Requires Protein Arginine Methyltransferase 5 (PRMT5)-mediated NF-?B p65 Methylation J. Biol. Chem. April 2014 Protein TA301086
PABPC1 CELF1 is an EIF4E binding protein that promotes translation of epithelial-mesenchymal transition effector mRNAs bioRxiv 2019 Protein TP307354
PACRG Pan-Cancer Analysis Links PARK2 to BCL-XL-Dependent Control of Apoptosis Neoplasia 2016 Protein TP322240
PAK4 Human CPPED1 belongs to calcineurin-like metallophosphoesterase superfamily and dephosphorylates PI3K-AKT pathway component PAK4 Journal of cellular and molecular medicine 2021 Protein TP302302
PARN The H/ACA complex disrupts triplex in hTR precursor to permit processing by RRP6 and PARN Nat Commun 2018 Protein TP307220
PARP1 MORC2 regulates DNA damage response through a PARP1-dependent pathway Nucleic Acids Research 2019 Protein TP710053
PCBP2 Unique C. elegans telomeric overhang structures reveal the evolutionarily conserved properties of telomeric DNA Nucleic Acids Res. Apr 2015 Protein TP310035
PCBP3 Prevalence and architecture of posttranscriptionally impaired synonymous mutations in 8,320 genomes across 22 cancer types Nucleic Acids Res. 2020 Protein TP329176
PDCD1 Direct therapeutic targeting of immune checkpoint PD-1 in pancreatic cancer Br. J. Cancer 2018 Protein LY401555
PDCD1 The prognostic role of immune checkpoint markers programmed cell death protein 1 (PD-1) and programmed death ligand 1 (PD-L1) in a large, multicenter prostate cancer cohort oncotarget 2016 Protein LY401555
PDCD1 Assessing PD-L1 and PD-1 in Non-Small Cell Lung Cancer (NSCLC): a Novel Immunoscore Approach Clinical Lung Cancer 2016 Protein LY401555
PDE1C A dominant variant in the PDE1C gene is associated with nonsyndromic hearing loss Hum. Genet. 2018 Protein TP760557
PDE4A Resveratrol directly targets DDX5 resulting in suppression of the mTORC1 pathway in prostate cancer Cell Death Dis May 2016 Protein TP307765
PDGFD Neuropilin 1 binds platelet-derived growth factor (PDGF)-D and is a co-receptor in PDGF-D/PDGF receptor β signaling J. Cell. Sci 2017 Protein TP760442
PDIA3 Protein disulfide isomerase plasma levels in healthy humans reveal proteomic signatures involved in contrasting endothelial phenotypes Redox Biology 2019 Protein TP305940
PDIA6 Tumor-associated autoantibodies from mouse breast cancer models are found in serum of breast cancer patients npj Breast Cancer 2021 Protein TP301710
PDIA6 Protein disulfide isomerase plasma levels in healthy humans reveal proteomic signatures involved in contrasting endothelial phenotypes Redox Biology 2019 Protein TP301710
PDK4 Functional Consequences of PDK4 Deficiency in Doberman Pinscher Fibroblasts Sci Rep 2020 Protein TP301656
PF4 Critical role of CXCL4 in the lung pathogenesis of influenza (H1N1) respiratory infection Mucosal Immunol 2017 Protein TP311322
PFKP PPARγ Links BMP2 and TGFβ1 Pathways in Vascular Smooth Muscle Cells, Regulating Cell Proliferation and Glucose Metabolism Cell Metab. 2017 Protein TP300673
PFN1 Phosphoglycerate mutase 1 promotes cancer cell migration independent of its metabolic activity Oncogene 2016 Protein TP302338
PGLYRP2 A Novel Innate Response of Human Corneal Epithelium to Heat-killed Candida albicans by Producing Peptidoglycan Recognition Proteins PLoS ONE Jun 2015 Protein TP315773
PGR Integration of Multitargeted Polymer-Based Contrast Agents with Photoacoustic Computed Tomography: An Imaging Technique to Visualize Breast Cancer Intratumor Heterogeneity ACS nano 2021 Protein TP321303
PHB2 Rabdosianone I, a Bitter Diterpene from an Oriental Herb, Suppresses Thymidylate Synthase Expression by Directly Binding to ANT2 and PHB2 Cancers 2021 Protein TP760501
PHLPP1 Role of PHLPP1 in inflammation response: Its loss contributes to gliomas development and progression Int. Immunopharmacol. Mar 2016 Protein TP303930
PHLPP1 An ATP-Site On-Off Switch That Restricts Phosphatase Accessibility of Akt Sci. Signal., May 2012; 5: ra37. Protein TP303930
PI3 High Serum Elafin Prediction of Poor Prognosis of Locoregional Esophageal Squamous Cell Carcinoma Cancers 2021 Protein TP303136
PICALM Central role for PICALM in amyloid-[beta] blood-brain barrier transcytosis and clearance Nature Neuroscience May 2015 Protein TP313791
PIK3CG Cilostazol Induces PGI2 Production via Activation of the Downstream Epac-1/Rap1 Signaling Cascade to Increase Intracellular Calcium by PLCe and to Activate p44/42 MAPK in Human Aortic Endothelial Cells PLoS ONE Jul 2015 Protein TP307790
PIN1 Analysis of binding interfaces of the human scaffold protein AXIN1 by peptide microarrays J. Biol. Chem. 2018 Protein TP302543
PIP Role of dendritic cell maturation factors produced by human invariant NKT cells in immune tolerance J. Leukoc. Biol. 2016 Protein TP303135
PISD The Mitochondrial Transacylase, Tafazzin, Regulates for AML Stemness by Modulating Intracellular Levels of Phospholipids Cell Stem Cell 2019 Protein TP761730
PKM The HIF-1α antisense long non-coding RNA drives a positive feedback loop of HIF-1α mediated transactivation and glycolysis Nature communications 2021 Protein TP721212
PLA2G12A Tumor-promoting effects of pancreatic cancer cell exosomes on THP-1-derived macrophages PLoS ONE 2018 Protein TP302955
PLAUR Ligand binding alters dimerization and sequestering of urokinase receptors in raft-mimicking lipid mixtures Biophys. J. Nov 2014 Protein TP301222
PLIN Autoantibodies Against Perilipin 1 as a Cause of Acquired Generalized Lipodystrophy Front Immunol 2018 Protein TP306292
PLK1 HIV-1 blocks the signaling adaptor MAVS to evade antiviral host defense after sensing of abortive HIV-1 RNA by the host helicase DDX3 Nat. Immunol 2016 Protein TP301795
PMPCB GRP75 overexpression rescues frataxin deficiency and mitochondrial phenotypes in Friedreich Ataxia cellular models Hum. Mol. Genet. 2018 Protein TP315039
PNP Evidence for purine nucleoside phosphorylase (PNP) release from RAT C6 glioma cells J. Neurochem 2017 Protein TP310759
PODN Podocan is expressed in blood and adipose tissue and correlates negatively with the induction of diabetic nephropathy Journal of Medicinal Chemistry 2017 Protein TP305567
PODXL Membranous expression of podocalyxin-like protein is an independent factor of poor prognosis in urothelial bladder cancer British Journal of Cancer doi:10.1038/bjc.2013.215 Protein LY401657
POLK A stapled POL κ peptide targets REV1 to inhibit mutagenic translesion synthesis Environ. Mol. Mutagen. 2020 Protein TP319806
POMT1 Enhanced influenza A H1N1 T cell epitope recognition and cross-reactivity to protein-O-mannosyltransferase 1 in Pandemrix-associated narcolepsy type 1 Nature communications 2021 Protein LC421404
PON1 PON1 deficiency promotes TREM2 pathway-mediated microglial phagocytosis and inhibits LPS-induced pro-inflammatory cytokines release Research Square 2020 Protein TP310356
POT1 An H2A Histone Isotype, H2ac, Associates with Telomere and Maintains Telomere Integrity PLoS ONE May 2016 Protein TP316275
POT1 The OB-fold domain 1 of human POT1 recognizes both telomeric and non-telomeric DNA motifs Biochimie Apr 2015 Protein TP316275
POU5F1 A systematic approach to quantitative Western blot analysis Analytical Biochemistry 2020 Protein LY400950
POU5F1 Pioneer transcription factors target partial DNA motifs on nucleosomes to initiate reprogramming Cell Apr 2015 Protein TP311998
PPIA Cyclosporine A binding to COX-2 reveals a novel signaling pathway that activates the IRE1α unfolded protein response sensor Sci Rep 2018 Protein TP303307
PPM1G WIP1 Phosphatase as a Potential Therapeutic Target in Neuroblastoma PLoS ONE Feb 2015 Protein TP313685
PPM1H WIP1 Phosphatase as a Potential Therapeutic Target in Neuroblastoma PLoS ONE Feb 2015 Protein TP317548
PPP1CB Inhibitory Member of the Apoptosis-stimulating Proteins of the p53 Family (iASPP) Interacts with Protein Phosphatase 1 via a Noncanonical Binding Motif J. Biol. Chem., Dec 2011; 286: 43039 - 43044. Protein TP301142
PPP2R5D Dysregulation of PP2A-Akt Interaction Contributes to Sucrose Non-Fermenting Related Kinase (SNRK) deficiency Induced Insulin Resistance in Adipose Tissue Molecular Metabolism 2019 Protein TP301945
PRMT1 Dynamic arginine methylation of TNF receptor associated factor 6 regulates Toll-like receptor signaling J. Biol. Chem. Jul 2015 Protein TP324239
PRMT5 Aberrant expression of CITED2 promotes prostate cancer metastasis by activating the nucleolin-AKT pathway Nat Commun 2018 Protein TP303458
PROM1 Functional links between gelatinase B/matrix metalloproteinase-9 and prominin-1/CD133 in diabetic retinal vasculopathy and neuropathy Prog Retin Eye Res July 2014 Protein TP321611
PROP1 DNA aptamers against the DUX4 protein reveal novel therapeutic implications for FSHD FASEB J. 2020 Protein TP318746
PROP1 Involvement of PIT-1-reactive cytotoxic T lymphocytes in anti-PIT-1 antibody syndrome J. Clin. Endocrinol. Metab. Jun 2014 Protein TP318746
PROP1 Involvement of PIT-1-Reactive Cytotoxic TLymphocytes in Anti-PIT-1 Antibody Syndrome J Clin Endocrinol Metab Jun 2014 Protein TP318746
PROS1 An engineered Axl 'decoy receptor' effectively silences the Gas6-Axl signaling axis Nat. Chem. Biol. Sep 2014 Protein TP302073
Protein Inactivation of Chibby affects function of motile airway cilia J. Cell Biol., Apr 2009; 185: 225 - 233. Protein
PROZ Identification of a novel natriuretic protein in patients with cerebral-renal salt wasting - implications for enhanced diagnosis The American Journal of the Medical Sciences 2020 Protein LC401283
PRSS1 Antigen-specificity of antiretinal antibodies in patients with noninfectious uveitis Canadian Journal of Ophthalmology / Journal Canadien d'Ophtalmologie 2017 Protein TP721067
PRY2 Proteome-wide epitope mapping of antibodies using ultra-dense peptide arrays Mol. Cell Proteomics. April 2014 Protein LY424151
PS100001 Restored immunosuppressive effect of mesenchymal stem cells on B cells after OAZ downregulation in patients with systemic lupus erythematosus Arthritis & rheumatology Sep 2014 Protein TF81001
PS100001 Matrix Metalloproteinase-19 Promotes Metastatic Behavior In Vitro and is Associated with Increased Mortality in Non-small Cell Lung Cancer Am. J. Respir. Crit. Care Med. Sep 2014 Protein LY500009
PS100010 The Use of a Stably Expressed FRET Biosensor for Determining the Potency of Cancer Drugs PLoS ONE Sep 2014 Protein
PSG1 Cystathionine ß-synthase regulates endothelial function via protein S-sulfhydration FASEB J. Sep 2015 Protein TP304978
PSMA1 Ultrasensitive detection of cancer biomarkers by nickel-based isolation of polydisperse extracellular vesicles from blood EBioMedicine 2019 Protein TP760007
PTBP1 RNP-MaP: In-cell analysis of protein interaction networks defines functional hubs in RNA bioRxiv 2020 Protein TP301779
PTCH1 Hedgehog signaling in the airway epithelium of patients with chronic obstructive pulmonary disease Sci Rep 2019 Protein LY424834
PTEN The Axonal Membrane Protein PRG2 Inhibits PTEN and Directs Growth to Branches Cell Rep 2019 Protein TP302627
PTEN ATM-mediated PTEN phosphorylation promotes PTEN nuclear translocation and autophagy in response to DNA-damaging agents in cancer cells Autophagy Feb 2015 Protein TP710023
PTGIS Calpain 1 cleaves and inactivates prostacyclin synthase in mesenteric arteries from diabetic mice Basic Res. Cardiol 2017 Protein TP311030
PTGR1 Mapping Novel Metabolic Nodes Targeted by Anti-Cancer Drugs that Impair Triple-Negative Breast Cancer Pathogenicity ACS Chem. Biol 2017 Protein TP306692
PTK2 Intracellular HMGB1 Negatively Regulates Efferocytosis J. Immunol., Nov 2011; 187: 4686 - 4694. Protein TP319839
PTK7 PTK7-Targeting CAR T-cells for the Treatment of Lung Cancer and other Malignancies Research Square 2020 Protein TP323416
PTK7 Sgc8-c Aptamer as a Potential Theranostic Agent for Hemato-Oncological Malignancies Cancer Biother. Radiopharm. 2020 Protein TP700163
PTP4A3 PRL-3 promotes ubiquitination and degradation of AURKA and colorectal cancer progression via dephosphorylation of FZR1 Cancer Res. 2018 Protein TP312193
PUF60 The prevalence and clinical significance of anti-PUF60 antibodies in patients with idiopathic inflammatory myopathy Clin. Rheumatol. 2018 Protein TP323492
PUF60 PUF60: a prominent new target of the autoimmune response in dermatomyositis and Sjögren's syndrome Ann. Rheum. Dis. Aug 2015 Protein TP323492
PUMA HER2 Phosphorylates and Destabilizes Pro-Apoptotic PUMA, Leading to Antagonized Apoptosis in Cancer Cells PLoS ONE e78836 Nov 2013 Protein TP325345
PVRIG Translational plasticity facilitates the accumulation of nonsense genetic variants in the human population Genome Res. 2016 Protein LY411386
PXN Autophagy Promotes Focal Adhesion Disassembly and Cell Motility of Metastatic Tumor Cells through the Direct Interaction of Paxillin with LC3 Cell Rep May 2016 Protein TP313811
PXN Paxillin and focal adhesion kinase colocalise in human skeletal muscle and its associated microvasculature Histochem. Cell Biol. Mar 2014 Protein TP313811
PXR protein Cyclin-dependent kinase 2 negatively regulates human pregnane X receptor-mediated CYP3A4 gene expression in HepG2 liver carcinoma cells J. Biol. Chem., Sep 2008; 10.1074/jbc.M806132200. Protein TP305691
RAB10 Vitamin B12 modulates Parkinson's disease LRRK2 kinase activity through allosteric regulation and confers neuroprotection Cell research 2019 Protein TP301464
RAB3A Novel antibodies reveal presynaptic localization of C9orf72 protein and reduced protein levels in C9orf72 mutation carriers Acta Neuropathol Commun 2018 Protein TP303973
RAB3C Novel antibodies reveal presynaptic localization of C9orf72 protein and reduced protein levels in C9orf72 mutation carriers Acta Neuropathol Commun 2018 Protein TP301436
RAB3D Novel antibodies reveal presynaptic localization of C9orf72 protein and reduced protein levels in C9orf72 mutation carriers Acta Neuropathol Commun 2018 Protein LY418099
RAB3IP Insufficiency of ciliary cholesterol in hereditary Zellweger syndrome EMBO J. 2020 Protein TP760069
RAB5C Epigenetic activation of a cryptic TBC1D16 transcript enhances melanoma progression by targeting EGFR Nat. Med. Jun 2015 Protein TP310698
RAB7A α-Catenin levels determine direction of YAP/TAZ response to autophagy perturbation Nature communications 2021 Protein TP301776
RAB7A Early to Intermediate Steps of Tumor Embolic Formation Involve Specific Proteolytic Processing of E-Cadherin Regulated by Rab7 Mol. Cancer Res., Jun 2012; 10: 713 - 726. Protein TP301776
RACK1 A novel UBE2T inhibitor suppresses Wnt/β-catenin signaling hyperactivation and gastric cancer progression by blocking RACK1 ubiquitination Oncogene 2020 Protein TP305092
RAD18 USP7 is essential for maintaining Rad18 stability and DNA damage tolerance Oncogene May 2015 Protein TP301700
RAG1 Physiological significance of Rag1 in neuronal death, especially optic neuropathy FEBS J. Oct 2014 Protein LY424712
RAGE A novel monoclonal antibody targeting carboxymethyllysine, an advanced glycation end product in atherosclerosis and pancreatic cancer PLoS ONE 2018 Protein TP720357
RASA1 Small Molecule KRAS Agonist for Mutant KRAS Cancer Therapy Mol. Cancer 2019 Protein TP305473
RASGRP1 Small Molecule KRAS Agonist for Mutant KRAS Cancer Therapy Mol. Cancer 2019 Protein TP312473
RASGRP2 Memory B Cells Activate Brain-Homing, Autoreactive CD4+ T Cells in Multiple Sclerosis Cell 2018 Protein TP312719
RBCK1 The paracaspase MALT1 cleaves HOIL1 reducing linear ubiquitination by LUBAC to dampen lymphocyte NF-?B signalling Nat Commun Nov 2015 Protein TP303906
RBP1 Identification of a novel natriuretic protein in patients with cerebral-renal salt wasting - implications for enhanced diagnosis The American Journal of the Medical Sciences 2020 Protein TP314515
RBP1 Importance of ALDH1A enzymes in determining human testicular retinoic acid concentrations J. Lipid Res. Dec 2014 Protein TP314515
RBPJ Autophagy Controls CSL/RBPJκ Stability through a p62/SQSTM1-Dependent Mechanism Cell Rep 2018 Protein TP760429
RBPMS The RNA binding protein RBPMS is a selective marker of ganglion cells in the mammalian retina J. Comp. Neurol. Dec 2013. Protein LY425258
RC219918 The Coordination of Netrin Signal Transduction via TUBB3 and JNK1 in Axon Thesis Jul 2013 Protein TP300755
RDH11 Sample matrix has a major impact on accuracy of peptide quantification: Assessment of calibrator and internal standard selection and method validation Analytical chemistry Dec 2015 Protein TP305003
RDH11 Sample matrix has a major impact on accuracy of peptide quantification: Assessment of calibrator and internal standard selection and method validation Analytical chemistry Dec 2015 Protein PH305003
RDX Are ERM (ezrin/radixin/moesin) proteins targets for autoantibodies in demyelinating neuropathies? Hum. Immunol. Oct 2014 Protein TP307953
RELA Highly efficient expression of circular RNA aptamers in cells using autocatalytic transcripts Nat. Biotechnol. 2019 Protein TP320780
RELA Detecting transcription factors with allosteric DNA-Silver nanocluster switches Analytica Chimica Acta 2018 Protein TP320780
RELA The M. tuberculosis HAD phosphatase (Rv3042c) interacts with host proteins and is inhibited by Clofazimine Cellular and Molecular Life Sciences Mar 2016 Protein TP320780
RELA FOXO3-NF-?B RelA Protein Complexes Reduce Proinflammatory Cell Signaling and Function J. Immunol. Nov 2015 Protein TP320780
RELA MYB Elongation Is Regulated by the Nucleic Acid Binding of NF?B p50 to the Intronic Stem-Loop Region PLoS ONE Apr 2015 Protein TP320780
RELA Functional characterization of a competitive peptide antagonist of p65 in human macrophage-like cells suggests therapeutic potential for chronic inflammation Drug Design, Development and Therapy Dec 2014 Protein TP320780
RELA Novel p65 Binding Glucocorticoid-induced Leucine Zipper Peptide Suppresses Experimental Autoimmune Encephalomyelitis J. Biol. Chem., Dec 2011; 286: 44799 - 44810. Protein TP320780
RETN Interaction between Esophageal Squamous Cell Carcinoma and Adipose Tissue in Vitro Am. J. Pathol. Mar 2016 Protein TP310942
RFTN2 Raftlin: a New Biomarker in Human Sepsis Inflammation Dec 2013. Protein TP310724
RHOB Mutations disrupting neuritogenesis genes confer risk for cerebral palsy Nat Genet 2020 Protein TP701009
RIG-I Quantitation of the Dynamic Profiles of the Innate Immune Response Using Multiplex Selected Reaction Monitoring–Mass Spectrometry Mol. Cell. Proteomics, Jun 2013; 12: 1513 - 1529. Protein TP317615
RIPK1 Receptor-interacting Ser/Thr kinase 1 (RIPK1) and myosin IIA-dependent ceramidosomes form membrane pores that mediate blebbing and necroptosis J. Biol. Chem. 2018 Protein TP302050
RND3 Rnd3 as a Novel Target to Ameliorate Microvascular Leakage J Am Heart Assoc Apr 2016 Protein TP304479
RNF114 Chemoproteomics-enabled discovery of covalent RNF114-based degraders that mimic natural product function Cell chemical biology 2021 Protein TP309752
RNF114 Chemoproteomics-Enabled Ligand Screening Yields Covalent RNF114-Based Degraders that Mimic Natural Product Function bioRxiv 2020 Protein TP309752
RNF2 TRIM37 is a new histone H2A ubiquitin ligase and breast cancer oncoprotein Nature Nov 2014 Protein TP303089
RNF214 Proteome-wide epitope mapping of antibodies using ultra-dense peptide arrays Mol. Cell Proteomics. April 2014 Protein LY403969
RNH1 Migration towards SDF-1 selects angiogenin-expressing bone marrow monocytes endowed with cardiac reparative activity in patients with previous myocardial infarction Stem Cell Res Ther Apr 2015 Protein TP308360
ROR1 Spontaneous Immunity Against the Receptor Tyrosine Kinase ROR1 in Patients with Chronic Lymphocytic Leukemia PLoS ONE Nov 2015 Protein TP314967
RORA The CH25H-CYP7B1-RORα axis of cholesterol metabolism regulates osteoarthritis Nature 2019 Protein TP302926
RPE65 Antigen-specificity of antiretinal antibodies in patients with noninfectious uveitis Canadian Journal of Ophthalmology / Journal Canadien d'Ophtalmologie 2017 Protein TP310433
RPS4X Identification of Ribosomal Protein S4, Y-Linked 1 as a cyclosporin A plus corticosteroid resistance gene J. Autoimmun. 2020 Protein LY423563
RPS4Y1 Identification of Ribosomal Protein S4, Y-Linked 1 as a cyclosporin A plus corticosteroid resistance gene J. Autoimmun. 2020 Protein LY423389
RPS6KB1 Activation of mTORC1 at late endosomes misdirects T cell fate decision in older individuals Science immunology 2021 Protein TP317324
RPS6KB1 The DPYSL2 gene connects mTOR and schizophrenia Transl Psychiatry 2016 Protein TP317324
RRM1 Antibody-assisted target identification reveals afatinib, an EGFR covalent inhibitor, down-regulating ribonucleotide reductase Oncotarget 2018 Protein TP300726
RRM2 Antibody-assisted target identification reveals afatinib, an EGFR covalent inhibitor, down-regulating ribonucleotide reductase Oncotarget 2018 Protein TP305718
RRM2 Anti-Peptide Monoclonal Antibodies Generated for Immuno-Multiple Reaction Monitoring-Mass Spectrometry Assays Have a High Probability of Supporting Western blot and ELISA Mol. Cell Proteomics Feb 2015 Protein LY431390
RUNX1 Hyperglycemia and redox status regulate RUNX2 DNA-binding and an angiogenic phenotype in endothelial cells Microvasc. Res. Oct 2014 Protein TP323854
RUNX2 A RUNX2 stabilization pathway mediates physiologic and pathologic bone formation Nat Commun 2020 Protein TP760214
S100A9 CD16 is indispensable for antibody-dependent cellular cytotoxicity by human monocytes Sci Rep 2016 Protein TP308250
SAA2 Renal progenitor cells revert LPS-induced endothelial-to-mesenchymal transition by secreting CXCL6, SAA4, and BPIFA2 antiseptic peptides FASEB J. 2019 Protein TP304977
SAA2 Continuous PTH in Male Mice Causes Bone Loss Because It Induces Serum Amyloid A (SAA) Endocrinology 2018 Protein TP304977
SAE1 Clinical characteristics of anti-SAE antibodies in Chinese patients with dermatomyositis in comparison with different patient cohorts Sci Rep 2017 Protein TP301820
SAG Antigen-specificity of antiretinal antibodies in patients with noninfectious uveitis Canadian Journal of Ophthalmology / Journal Canadien d'Ophtalmologie 2017 Protein TP320057
SAMHD1 Conserved Herpesvirus Protein Kinases Target SAMHD1 to Facilitate Virus Replication Cell Rep 2019 Protein TP306013
SAMHD1 The expression profile of sterile alpha motif and histidine-aspartate domain-containing protein 1 (SAMHD1) in feline tissues Veterinary Immunology and Immunopathology 2017 Protein LY414526
SATB1 SATB1 is an independent prognostic factor in radically resected upper gastrointestinal tract adenocarcinoma Virchows Arch. Oct 2014 Protein LY427355
SATB2 SATB1 is an independent prognostic factor in radically resected upper gastrointestinal tract adenocarcinoma Virchows Arch. Oct 2014 Protein LY414656
SBSN Sox2 induces tumorigenesis and angiogenesis of early stage esophagealsquamous cell carcinoma through secretion of Suprabasin Carcinogenesis 2020 Protein TP319831
SCG2 REST Regulates Non-Cell-Autonomous Neuronal Differentiation and Maturation of Neural Progenitor Cells via Secretogranin II J. Neurosci. Nov 2015 Protein TP305382
SCGB2A2 Nanoscale flow cytometry for immunophenotyping and quantitating extracellular vesicles in blood plasma Nanoscale 2021 Protein TP324550
SEC24B Auto-regulation of Secretory Flux by Sensing and Responding to the Folded Cargo Protein Load in the Endoplasmic Reticulum Cell 2019 Protein TP319074
SERBP1 Tumor-associated autoantibodies from mouse breast cancer models are found in serum of breast cancer patients npj Breast Cancer 2021 Protein TP301092
SERCA2 JNK2, A Newly-Identified SERCA2 Enhancer, Augments an Arrhythmic [Ca2+]SR Leak-Load Relationship Circulation research 2020 Protein TP762182
serpina1 Endothelial-Mesenchymal Transition in Vascular Calcification of Ins2Akita/+ Mice PLoS ONE 2016 Protein TP302082
SERPINA1 Serine Protease Activation Essential for Endothelial-Mesenchymal Transition in Vascular Calcification Circ. Res. Aug 2015 Protein TP302082
SERPINA6 Anti-Peptide Monoclonal Antibodies Generated for Immuno-Multiple Reaction Monitoring-Mass Spectrometry Assays Have a High Probability of Supporting Western blot and ELISA Mol. Cell Proteomics Feb 2015 Protein LY419763
SERPINB1 Plasma serpinB1 is related to insulin sensitivity but not pancreatic β-Cell function in non-diabetic adults Physiol Rep 2017 Protein TP302138
SERPINB1 SerpinB1 Promotes Pancreatic ß Cell Proliferation Cell Metab. Dec 2015 Protein TP302138
SERPINB2 Post-injury nose-to-brain delivery of Activin A and SerpinB2 reduces brain damage in a mouse stroke model Molecular Therapy 2018 Protein TP303139
SERPINB3 The kinetic profile and clinical implication of SCC-Ag in squamous cervical cancer patients undergoing radical hysterectomy using the Simoa assay: a prospective observational study BMC Cancer 2020 Protein TP302683
SETDB1 Polycomb Repressive Complex 2 Methylates Elongin A to Regulate Transcription Mol. Cell 2017 Protein TP326620
SF268 ANGPTL4 Induces TMZ Resistance of Glioblastoma by Promoting Cancer Stemness Enrichment via the EGFR/AKT/4E-BP1 Cascade Int J Mol Sci 2019 Protein LY500060
SGPL1 Site-Dependent Cysteine Lipidation Potentiates the Activation of Proapoptotic BAX Cell Rep 2020 Protein TP308705
SIGLEC12 AK002, a Humanized Sialic Acid-Binding Immunoglobulin-Like Lectin-8 Antibody that Induces Antibody-Dependent Cell-Mediated Cytotoxicity against Human Eosinophils and Inhibits Mast Cell-Mediated Anaphylaxis in Mice Int. Arch. Allergy Immunol. 2019 Protein TP307808
SIRT1 Rescue of retinal ganglion cells in optic nerve injury using cell-selective AAV mediated delivery of SIRT1 Gene therapy 2021 Protein TP318134
SIRT7 Regulation of Serine-Threonine Kinase Akt Activation by NAD(+)-Dependent Deacetylase SIRT7 Cell Rep 2017 Protein TP305658
SKP2 Inhibiting the role of Skp2 suppresses cell proliferation and tumorigenesis of human gastric cancer cells via the upregulation of p27kip1 Mol Med Rep 2016 Protein TP314001
SLC14A1 Expression and localization of a UT-B urea transporter in the human bladder Am. J. Physiol. Renal Physiol. Sep 2014 Protein TP308509
SLC14A1 Expression and localization of a UT-B urea transporter in the human bladder Am. J. Physiol. Renal Physiol. Sep 2014 Protein LY402465
SLC14A1 Expression and localization of a UT-B urea transporter in the human bladder Am. J. Physiol. Renal Physiol. Sep 2014 Protein LY426961
SLC16A1 Bioinformatic analysis of membrane and associated proteins in murine cardiomyocytes and human myocardium Scientific data 2020 Protein LY401069
SLC22A15 Deorphaning a solute carrier 22 family member, SLC22A15, through functional genomic studies FASEB J 2020 Protein TP305541
SLC25A5 Rabdosianone I, a Bitter Diterpene from an Oriental Herb, Suppresses Thymidylate Synthase Expression by Directly Binding to ANT2 and PHB2 Cancers 2021 Protein TP308949
SLC25A5 The pleiotropic regulation of cyclin D1 by newly identified sesaminol-binding protein ANT2 Oncogenesis 2017 Protein TP308949
SLC2A1 Insulin signaling via the PI3-kinase/Akt pathway regulates airway glucose uptake and barrier function in a CFTR-dependent manner Am. J. Physiol. Lung Cell Mol. Physiol. 2017 Protein LC416593
SLC2A10 Insulin signaling via the PI3-kinase/Akt pathway regulates airway glucose uptake and barrier function in a CFTR-dependent manner Am. J. Physiol. Lung Cell Mol. Physiol. 2017 Protein LC410718
SLC35B1 AXER is an ATP/ADP exchanger in the membrane of the endoplasmic reticulum Nat Commun 2018 Protein LY401770
SLC6A4 Low-level repeated exposure to diazinon and chlorpyrifos decrease anxiety-like behaviour in adult male rats as assessed by marble burying behaviour Neurotoxicology Aug 2015 Protein TP310187
SLC7A5 The amino acid transporter SLC7A5 confers a poor prognosis in the highly proliferative breast cancer subtypes and is a key therapeutic target in luminal B tumours Breast Cancer Res. 2018 Protein LY401180
SLC9A3R1 Expression of Na+/H+ exchanger regulatory factor 1 in autosomal-dominant polycystic kidney disease J. Int. Med. Res. Jul 2015 Protein TP301653
SLURP1 Cholinergic Signaling Mechanisms and Early Implant Healing Phases in Healthy Versus Generalized Aggressive Periodontitis Patients: A prospective, case-control study J. Clin. Periodontol. 2019 Protein LY412478
SMAD2 M10, a caspase cleavage product of the hepatocyte growth factor receptor, interacts with Smad2 and demonstrates antifibrotic properties in vitro and in vivo Transl Res Dec 2015 Protein TP304604
SMAD4 M10, a caspase cleavage product of the hepatocyte growth factor receptor, interacts with Smad2 and demonstrates antifibrotic properties in vitro and in vivo Transl Res Dec 2015 Protein TP301828
SMARCB1 A lncRNA-SWI/SNF complex crosstalk controls transcriptional activation at specific promoter regions Nat Commun 2020 Protein TP317885
SMN ALS-associated mutations in FUS disrupt the axonal distribution and function of SMN Hum. Mol. Genet., May 2013; 10.1093/hmg/ddt222. Protein TP321367
SMPD3 Interaction of Synaptosomal-Associated Protein 25 with Neutral Sphingomyelinase 2: Functional Impact on the Sphingomyelin Pathway Neuroscience 2019 Protein TP318441
SNAP25 Interaction of Synaptosomal-Associated Protein 25 with Neutral Sphingomyelinase 2: Functional Impact on the Sphingomyelin Pathway Neuroscience 2019 Protein TP302068
SNAP25 Nanobodies reveal an extra-synaptic population of SNAP-25 and Syntaxin 1A in hippocampal neurons MAbs 2018 Protein TP302068
SNAP25 SNAP-25 is a promising novel cerebrospinal fluid biomarker for synapse degeneration in Alzheimer's disease Mol Neurodegener Nov 2014 Protein TP302068
SNAP25 Targeting synaptic pathology with a novel affinity mass spectrometry approach Mol. Cell Proteomics Jun 2014 Protein TP302068
SNAP29 Regulation of Autophagic Flux by the 20S Proteasome Cell Chem Biol 2019 Protein TP302179
SNRPC The process of somatic hypermutation increases polyreactivity for central nervous system antigens in primary central nervous system lymphoma Haematologica 2020 Protein TP318418
SNTG1 Enhanced influenza A H1N1 T cell epitope recognition and cross-reactivity to protein-O-mannosyltransferase 1 in Pandemrix-associated narcolepsy type 1 Nature communications 2021 Protein TP311170
SOCS1 IFN-λ4 Attenuates Antiviral Responses by Enhancing Negative Regulation of IFN Signaling J. Immunol. 2017 Protein LY401230
SOX18 Functional domain analysis of SOX18 transcription factor using a single-chain variable fragment-based approach MAbs 2018 Protein LY413065
SOX2 Functional domain analysis of SOX18 transcription factor using a single-chain variable fragment-based approach MAbs 2018 Protein LY401083
SOX2 Pioneer transcription factors target partial DNA motifs on nucleosomes to initiate reprogramming Cell Apr 2015 Protein TP300757
SOX4 SOXC Transcription Factors Induce Cartilage Growth Plate Formation in Mouse Embryos by Promoting Noncanonical WNT Signaling J. Bone Miner. Res. Mar 2015 Protein TP309139
SOX9 Context-specific role of SOX9 in NF-Y mediated gene regulation in colorectal cancer cells Nucleic Acids Res. Jun 2015 Protein TP308944
SP1 Transcriptional suppression of CPI-17 gene expression in vascular smooth muscle cells by TNF, KLF4, and Sp1 is associated with LPS-induced vascular hypocontractility, hypotension, and mortality Mol. Cell. Biol. 2019 Protein TP760592
SPAST HIPK2 Phosphorylates the Microtubule-Severing Enzyme Spastin at S268 for Abscission Cells 2019 Protein TP320458
SPI1 MeCP2 Promotes Colorectal Cancer Metastasis by Modulating ZEB1 Transcription Cancers (Basel) 2020 Protein AR51789PU-N
SPOP Quantification of mutant SPOP proteins in prostate cancer using mass spectrometry-based targeted proteomics J Transl Med 2017 Protein TP301551
SPP1 Osteopontin isoforms differentially promote arteriogenesis in response to ischemia via macrophage accumulation and survival Lab. Invest. 2018 Protein TP310592
SPP1 Osteopontin isoforms differentially promote arteriogenesis in response to ischemia via macrophage accumulation and survival Lab. Invest. 2018 Protein TP305118
SPP1 Osteopontin isoforms differentially promote arteriogenesis in response to ischemia via macrophage accumulation and survival Lab. Invest. 2018 Protein TP304803
SPTAN1 Serum SNTF, a Surrogate Marker of Axonal Injury, Is Prognostic for Lasting Brain Dysfunction in Mild TBI Treated in the Emergency Department Front Neurol 2020 Protein TP318210
SRP54 Anti-signal recognition particle autoantibody ELISA validation and clinical associations Rheumatology (Oxford) Dec 2014 Protein TP301658
SRSF10 Identification of SRSF10 as a regulator of SMN2 ISS-N1 Human mutation 2020 Protein TP321759
SSAT1 MicroRNAs interfere with DNA methylation in rheumatoid arthritis synovial fibroblasts Rheumatic & Musculoskeletal Diseases 2016 Protein LY401040
STARD13 Proteome-wide epitope mapping of antibodies using ultra-dense peptide arrays Mol. Cell Proteomics. April 2014 Protein LY406044
STAT1a PARP9 and PARP14 cross-regulate macrophage activation via STAT1 ADP-ribosylation Nat Commun 2016 Protein TP313858
STIM1 STIM1 activates CRAC channels through rotation of the pore helix to open a hydrophobic gate Nat Commun 2017 Protein TP305678
STK38 NDR1 protein kinase promotes IL-17- and TNF-α-mediated inflammation by competitively binding TRAF3 EMBO Rep 2017 Protein TP304133
STK38 Stk38 protein kinase preferentially inhibits TLR9-activated inflammatory responses by promoting MEKK2 ubiquitination in macrophages Nat Commun May 2015 Protein TP304133
STK38L Amplification of F-Actin Disassembly and Cellular Repulsion by Growth Factor Signaling Dev. Cell 2017 Protein TP306074
STX1A Nanobodies reveal an extra-synaptic population of SNAP-25 and Syntaxin 1A in hippocampal neurons MAbs 2018 Protein TP328784
STX5 Plasma membrane cholesterol trafficking in steroidogenesis FASEB J. 2018 Protein TP304213
SYCE2 Somatic role of SYCE2: an insulator that dissociates HP1α from H3K9me3 and potentiates DNA repair Life Sci. Alliance 2018 Protein TP325261
SYK Interplay between HGAL and Grb2 proteins regulates B-cell receptor signaling Blood Adv 2019 Protein TP300413
SYNJ1 Human R1441C LRRK2 regulates the synaptic vesicle proteome and phosphoproteome in a Drosophila model of Parkinson's disease Hum. Mol. Genet. 2016 Protein TP315278
SYT1 CSF levels of synaptosomal-associated protein 25 and synaptotagmin-1 in first-episode psychosis subjects IBRO Reports 2020 Protein PH327252
SYT1 The pre-synaptic vesicle protein synaptotagmin is a novel biomarker for Alzheimer's disease Alzheimers Res Ther 2016 Protein TP327252
SYT5 Interactions of Antibodies to the Gram-Negative Gastric Bacterium Helicobacter pylori with the Synaptic Calcium Sensor Synaptotagmin 5, Correlate to Impaired Vesicle Recycling in SiMa Human Neuroblastoma Cells J. Mol. Neurosci. 2020 Protein LY418847
TACC3 A Highly Potent TACC3 Inhibitor as a Novel Anti-cancer Drug Candidate Mol. Cancer Ther. 2020 Protein TP310754
TAGLN2 Comparative Tissue Proteomics of Microdissected Specimens Reveals Novel Candidate Biomarkers of Bladder Cancer Mol. Cell Proteomics Jun 2015 Protein TP303473
TARBP2 DICER-ARGONAUTE2 Complex in Continuous Fluorogenic Assays of RNA Interference Enzymes PLoS ONE Mar 2015 Protein PH301043
TARDBP TDP-43 stabilizes G3BP1 mRNA: relevance to amyotrophic lateral sclerosis/frontotemporal dementia Brain : a journal of neurology 2021 Protein TP310639
TARDBP TDP-43 regulates the alternative splicing of hnRNP A1 to yield an aggregation-prone variant in amyotrophic lateral sclerosis Brain 2018 Protein TP710010
TARDBP A Liver-Enriched Long Non-Coding RNA, lncLSTR, Regulates Systemic Lipid Metabolism in Mice Cell Metab. Mar 2015 Protein TP310639
TARDBP Full-length TDP-43 forms toxic amyloid oligomers that are present in frontotemporal lobar dementia-TDP patients Nat Commun Sep 2014 Protein TP310639
TARDBP Dual vulnerability of TDP-43 to calpain and caspase-3 proteolysis after neurotoxic conditions and traumatic brain injury J. Cereb. Blood Flow Metab. Jun 2014 Protein TP310639
TBC1D1 WNK1 phosphorylation sites in TBC1D1 and TBC1D4 modulate cell surface expression of GLUT1 Arch. Biochem. Biophys. 2019 Protein TP307980
TBC1D4 WNK1 phosphorylation sites in TBC1D1 and TBC1D4 modulate cell surface expression of GLUT1 Arch. Biochem. Biophys. 2019 Protein TP312105
TBX19 Isolated adrenocorticotropic hormone deficiency as a form of paraneoplastic syndrome Pituitary 2018 Protein TP310787
TBX21 PD-1 Inhibitory Receptor Downregulates Asparaginyl Endopeptidase and Maintains Foxp3 Transcription Factor Stability in Induced Regulatory T Cells Immunity 2018 Protein TP307902
TBX5 SNP located in an AluJb repeat downstream of TMCO1, rs4657473, is protective for POAG in African Americans Br J Ophthalmol 2019 Protein TP316520
TDRP Immuno-moodulin: a new anxiogenic factor produced by Annexin-A1 transgenic autoimmune-prone T cells Brain, Behavior, and Immunity 2020 Protein TP313199
TDRP Immuno-moodulin: a new anxiogenic factor produced by autoimmune-prone T cells bioRxiv 2019 Protein TP313199
TFAP2a A Functional Variant Associated with Atrial Fibrillation Regulates PITX2c Expression through TFAP2a AJHG 2016 Protein TP304603
TFEB A novel curcumin analog binds to and activates TFEB in vitro and in vivo independent of MTOR inhibition Autophagy May 2016 Protein TP760282
TFPI2 Tissue factor pathway inhibitor‑2 is specifically expressed in ovarian clear cell carcinoma tissues in the nucleus, cytoplasm and extracellular matrix Oncology Reports 2021 Protein TP760523
TGFB1 A Novel Bioreactor System Capable of Simulating the In Vivo Conditions of Synovial Joints Tissue engineering. Part C, Methods 2020 Protein TP300973
TGFB1 Local Sympathectomy Promotes Antiinflammatory Responses and Relief of Paclitaxel-induced Mechanical and Cold Allodynia in Mice Anesthesiology 2020 Protein TP723438
TGFB1 Molecular mechanisms involved in TGF-β1-induced Muscle-derived stem cells differentiation to smooth muscle cells Am J Transl Res 2019 Protein TP300973
TGFB1 Oxidative stress is responsible for maternal diabetes-impaired transforming growth factor beta signaling in the developing mouse heart Am. J. Obstet. Gynecol. Jan 2015 Protein TP300973
THBS1 POSTN Promotes the Proliferation of Spermatogonial Cells by Activating the Wnt/β-Catenin Signaling Pathway Reproductive sciences (Thousand Oaks, Calif.) 2021 Protein TP314802
THBS1 Identification of a novel natriuretic protein in patients with cerebral-renal salt wasting - implications for enhanced diagnosis The American Journal of the Medical Sciences 2020 Protein TP314802
TIA1 Analysis of RNA-protein networks with RNP-MaP defines functional hubs on RNA Nat Biotechnol 2020 Protein TP319386
TIA1 RNP-MaP: In-cell analysis of protein interaction networks defines functional hubs in RNA bioRxiv 2020 Protein TP319386
TIMP2 Use of a Recombinant Biomarker Protein DDA Library Increases DIA Coverage of Low Abundance Plasma Proteins Journal of proteome research 2021 Protein TP723886
TJP1 Protein painting, an optimized MS-based technique, reveals functionally relevant interfaces of the PD-1/PD-L1 complex and the YAP2/ZO-1 complex J. Biol. Chem. 2019 Protein TP322836
TMEM173 Redox homeostasis maintained by GPX4 facilitates STING activation Nat. Immunol. 2020 Protein TP308418
TMEM240 The TMEM240 Protein, Mutated in SCA21, Is Expressed in Purkinje Cells and Synaptic Terminals Cerebellum 2020 Protein TP325178
TMEM5 The functional O-mannose glycan on a-dystroglycan contains a phospho-ribitol primed for matriglycan addition Elife Apr 2016 Protein TP303762
TMEM98 TMEM98, a novel secretory protein, promotes endothelial cell adhesion as well as vascular smooth muscle cell proliferation and migration Can. J. Physiol. Pharmacol. 2020 Protein TP301829
TMEM98 The Secreted Form of Transmembrane Protein 98 Promotes the Differentiation of T Helper 1 Cells J. Interferon Cytokine Res. May 2015 Protein TP301829
TMIE TMIE Defines Pore and Gating Properties of the Mechanotransduction Channel of Mammalian Cochlear Hair Cells Neuron 2020 Protein TP320050
TMPRSS4 Transmembrane protease, serine 4 (TMPRSS4) is upregulated in IPF lungs and increases the fibrotic response in bleomycin-induced lung injury PLoS ONE 2018 Protein TP303972
TNF Bone Marrow CX3CL1/Fractalkine is a New Player of the Pro-Angiogenic Microenvironment in Multiple Myeloma Patients Cancers (Basel) 2019 Protein TP723451
TNF Effect of tumor necrosis factor-α on the expression of the ammonia transporter Rhcg in the brain in mice with acute liver failure J Neuroinflammation 2018 Protein TP306983
TNF IL21R expressing CD14+CD16+ monocytes expand in multiple myeloma patients leading to increased osteoclasts Haematologica 2017 Protein TP306983
TNF Melanocyte pigmentation inversely correlates with MCP-1 production and angiogenesis-inducing potential FASEB J. Nov 2014 Protein TP306983
TNFRSF10B/DR5 Hepatitis B virus-triggered autophagy targets TNFRSF10B/death receptor 5 for degradation to limit TNFSF10/TRAIL response Autophagy 2016 Protein TP319808
TNFRSF11B Effect of Substrate Reduction Therapy in Comparison to Enzyme Replacement Therapy on Immune Aspects and Bone Involvement in Gaucher Disease Biomolecules 2020 Protein TP723343
TNFRSF1A Use of a Recombinant Biomarker Protein DDA Library Increases DIA Coverage of Low Abundance Plasma Proteins Journal of proteome research 2021 Protein TP723870
TNFSF10 Epigenome-wide DNA methylation profiling of portal vein tumor thrombosis (PVTT) tissues in hepatocellular carcinoma patients Neoplasia 2020 Protein TP750004
TNFSF11 Extracellular calcium regulates the adhesion and migration of osteoclast via integrin αv β3 / Rho A/Cytoskeleton signaling Cell Biol. Int. 2018 Protein TP723423
TP53 Upregulation of nucleoprotein AHNAK is associated with poor outcome of pancreatic ductal adenocarcinoma prognosis via mediating epithelial-mesenchymal transition J. Cancer 2019 Protein TP710022
TP53 mTOR kinase leads to PTEN-loss-induced cellular senescence by phosphorylating p53 Oncogene 2018 Protein TP300003
TP53 Analysis of binding interfaces of the human scaffold protein AXIN1 by peptide microarrays J. Biol. Chem. 2018 Protein TP300003
TP53 A Novel In Vitro CypD-Mediated p53 Aggregation Assay Suggests a Model for Mitochondrial Permeability Transition by Chaperone Systems J. Mol. Biol. 2016 Protein TP300003
TP53 Species-specific mutual regulation of p53 and miR-138 between human, rat and mouse Sci Rep May 2016 Protein TP300003
TP63 An Immunohistochemical Analysis of a Newly Developed, Mouse Monoclonal p40 (BC28) in Lung, Bladder, Skin, Breast, Prostate, and Head and Neck Cancers Arch. Pathol. Lab. Med., Feb 2014. Protein LY418475
TPH2 Serotonin and tryptophan metabolites, autoantibodies and gut microbiome in APECED Endocr Connect 2019 Protein TP321193
TPK1 The JAK2 Inhibitor Fedratinib Inhibits Thiamine Uptake - A Putative Mechanism for the Onset of Wernicke's Encephalopathy Drug Metab. Dispos. July 2014 Protein TP309721
TRAF3 E3 ligase Nedd4l promotes antiviral innate immunity by catalyzing K29-linked cysteine ubiquitination of TRAF3 Nature communications 2021 Protein TP318682
TRAF6 TRAF6 function as a novel co-regulator of Wnt3a target genes in prostate cancer EBioMedicine 2019 Protein TP319528
TRAF6 Ubiquitin-specific Protease 20 Regulates the Reciprocal Functions of β-Arrestin2 in Toll-like Receptor 4-promoted Nuclear Factor κB (NFκB) Activation Journal of Biological Chemistry 2016 Protein TP319528
TRAF6 Dynamic arginine methylation of TNF receptor associated factor 6 regulates Toll-like receptor signaling J. Biol. Chem. Jul 2015 Protein TP319528
TRH Vulnerability of Purkinje Cells Generated from Spinocerebellar Ataxia Type 6 Patient-Derived iPSCs Cell Rep 2016 Protein TP319231
TRIM33 The IgG2 isotype of anti-transcription intermediary factor 1-gamma autoantibodies is a biomarker of mortality in adult dermatomyositis Arthritis & rheumatology (Hoboken, N.J.) 2019 Protein TP312497
TRIM33 Time-Resolved Analysis Reveals Rapid Dynamics and Broad Scope of the CBP/p300 Acetylome Cell 2018 Protein TP710251
TRIM33 Anti-TIF1 antibodies (anti-p155) in adult patients with dermatomyositis: comparison of different diagnostic assays Ann Rheum Dis, Jan 2012; 10.1136/annrheumdis-2011-200871. Protein TP312497
TRPV3 TRPV3 expression and vasodilator function in isolated uterine radial arteries from non-pregnant and pregnant rats Vascul. Pharmacol. Apr 2016 Protein LY403422
TSPO Discovery of thienopyrrolotriazine derivatives to protect mitochondrial function against Aβ-induced neurotoxicity Eur J Med Chem 2017 Protein TP320107
TSPO Discovery of benzimidazole derivatives as modulators of mitochondrial function: A potential treatment for Alzheimer's disease Eur J Med Chem 2016 Protein TP320107
TTC33 Time-Resolved Analysis Reveals Rapid Dynamics and Broad Scope of the CBP/p300 Acetylome Cell 2018 Protein TP302360
TUBA1A Cross-talk between CDK4/6 and SMYD2 regulates gene transcription, tubulin methylation, and ciliogenesis Sci Adv 2020 Protein TP308669
TUBA3C Anti-tubulin-α-1C autoantibody in systemic lupus erythematosus: a novel indicator of disease activity and vasculitis manifestations Clin. Rheumatol. 2018 Protein TP304072
TUBB Screening Citrullinated Proteins in Synovial Tissues of Rheumatoid Arthritis Using 2-dimensional Western Blotting J Rheumatol, Mar 2013; 40: 219 - 227. Protein TP303629
TUBB3 Coordinated interaction of Down syndrome cell adhesion molecule and deleted in colorectal cancer with dynamic TUBB3 mediates Netrin-1-induced axon branching Neuroscience May 2015 Protein TP300755
TUBB3 Direct binding of TUBB3 with DCC couples netrin-1 signaling to intracellular microtubule dynamics in axon outgrowth and guidance J. Cell Sci., Jul 2013; 126: 3070 - 3081. Protein TP300755
TXN Up-regulation of thioredoxin 1 by aerobic exercise training attenuates endoplasmic reticulum stress and cardiomyocyte apoptosis following myocardial infarction Sports Medicine and Health Science 2020 Protein TP308876
TXNIP TXNIP Regulates Natural Killer Cell-Mediated Innate Immunity by Inhibiting IFN-γ Production during Bacterial Infection International journal of molecular sciences 2020 Protein TP310804
UBAP2L UBAP2L arginine methylation by PRMT1 modulates stress granule assembly Cell Death Differ. 2019 Protein TP301371
UBE2L3 The Level of Autoantibodies Targeting Eukaryote Translation Elongation Factor 1 a1 and Ubiquitin-Conjugating Enzyme 2L3 in Nondiabetic Young Adults Diabetes Metab J Nov2015 Protein TP308780
UBE2L3 Identification of Novel Autoantibodies in Type 1 Diabetic Patients Using a High-Density Protein Microarray Diabetes Jun 2014 Protein TP308780
UBE2T CaMKII-δ9 promotes cardiomyopathy through disrupting UBE2T-dependent DNA repair Nat. Cell Biol. 2019 Protein TP300748
UBR7 Manumycin Polyketides Act as Molecular Glues Between UBR7 and P53 to Impair Breast Cancer Pathogenicity bioRxiv 2019 Protein TP318298
UCMA In vivo protective effects of UCMA against cartilage degeneration in monosodium iodoacetate-induced osteoarthritis model Can. J. Physiol. Pharmacol. 2020 Protein TP721011
UCP2 Reduction of elevated proton leak rejuvenates mitochondria in the aged cardiomyocyte eLife 2020 Protein TP761109
UGT2B15 Human Hepatic UGT2B15 Developmental Expression Toxicol. Sci. Jun 2014 Protein TP315344
UMPS Metabolomics Identifies Pyrimidine Starvation as the Mechanism of 5-Aminoimidazole-4-Carboxamide-1-ß-Riboside-Induced Apoptosis in Multiple Myeloma Cells Mol. Cancer Ther., Jul 2013; 12: 1310 - 1321. Protein TP301324
UPF1 CSL controls telomere maintenance and genome stability in human dermal fibroblasts Nat Commun 2019 Protein TP308018
USP20 Ubiquitin-specific Protease 20 Regulates the Reciprocal Functions of β-Arrestin2 in Toll-like Receptor 4-promoted Nuclear Factor κB (NFκB) Activation Journal of Biological Chemistry 2016 Protein TP308051
USP24 USP24 promotes drug resistance during cancer therapy Cell death and differentiation 2021 Protein TP329472
USP24 USP24 induces IL-6 in tumor-associated microenvironment by stabilizing p300 and β-TrCP and promotes cancer malignancy Nat Commun 2018 Protein TP329472
USP24 EGF-mediated inhibition of ubiquitin-specific peptidase 24 expression has a crucial role in tumorigenesis Oncogene 2016 Protein TP329472
VASH2 Vasohibin 2 promotes human luminal breast cancer angiogenesis in a non-paracrine manner via transcriptional activation of fibroblast growth factor 2 Cancer Lett. 2016 Protein TP308692
VAV1 Phospholipase D2 (PLD2) is a guanine nucleotide exchange factor (GEF) for the GTPase Rac2 PNAS, Dec 2011; 108: 19617 - 19622. Protein TP324806
VAV2 Tyr42 phosphorylation of RhoA GTPase promotes tumorigenesis through nuclear factor (NF)-κB Free Radic. Biol. Med. 2017 Protein TP316175
VCL Autoantibodies against vinculin in patients with chronic inflammatory demyelinating polyneuropathy Journal of Neuroimmunology Oct 2015 Protein TP304576
VEGFC Myeloid-Derived Lymphatic Endothelial Cell Progenitors Significantly Contribute to Lymphatic Metastasis in Clinical Breast Cancer Am. J. Pathol. 2019 Protein TP723474
VGF Longitudinal CSF proteomics identifies NPTX2 as a prognostic biomarker of Alzheimer\'s disease Alzheimer's & dementia : the journal of the Alzheimer's Association 2021 Protein TP309477
VHL Protein 4.1 R Influences Myogenin Protein Stability and Skeletal Muscle Differentiation Journal of Biological Chemistry 2016 Protein TP316151
VIM A Binding Potency Assay for Pritumumab and Ecto-Domain Vimentin Methods Mol. Biol. 2019 Protein TP301546
VSNL1 A novel method for the rapid detection of post-translationally modified visinin-like protein 1 in rat models of brain injury Brain Inj 2017 Protein TP305337
WNT10A Roles of Heparan Sulfate Sulfation in Dentinogenesis J. Biol. Chem., Apr 2012; 287: 12217 - 12229. Protein LY403062
WWTR1 Yorkie Growth-Promoting Activity Is Limited by Atg1-Mediated Phosphorylation Dev. Cell 2020 Protein TP304082
XPNPEP1 Anti-Peptide Monoclonal Antibodies Generated for Immuno-Multiple Reaction Monitoring-Mass Spectrometry Assays Have a High Probability of Supporting Western blot and ELISA Mol. Cell Proteomics Feb 2015 Protein LY402779
XRCC1 Efficient embryonic homozygous gene conversion via RAD51-enhanced interhomolog repair Cell 2021 Protein TP304952
XRCC4 Quantification of XRCC and DNA-PK proteins in cancer cell lines and human tumors by LC-MS/MS Bioanalysis May 2014 Protein TP318029
XRCC4 Quantification of XRCC and DNA-PK proteins in cancer cell lines and human tumors by LC-MS/MS Bioanalysis May 2014 Protein PH318029
XRCC6 CSL controls telomere maintenance and genome stability in human dermal fibroblasts Nat Commun 2019 Protein TP304048
XRN2 Hepatitis C Virus Subverts Liver-Specific miR-122 to Protect the Viral Genome from Exoribonuclease Xrn2 Cell Host Microbe Aug 2014 Protein TP323980
YAP1 Yorkie Growth-Promoting Activity Is Limited by Atg1-Mediated Phosphorylation Dev. Cell 2020 Protein TP325864
YAP1 Protein painting, an optimized MS-based technique, reveals functionally relevant interfaces of the PD-1/PD-L1 complex and the YAP2/ZO-1 complex J. Biol. Chem. 2019 Protein TP325864
YBX1 Single mRNP Analysis Reveals that Small Cytoplasmic mRNP Granules Represent mRNA Singletons Cell Rep 2019 Protein TP309835
YBX1 Single mRNP analysis by super-resolution microscopy and fluorescence correlation spectroscopy reveals that small mRNP granules represent mRNA singletons bioRxiv 2019 Protein TP309835
YBX1 Autism-specific maternal autoantibodies recognize critical proteins in developing brain Translational Psychiatry 3, e277 doi:10.1038/tp.2013.50 Protein LY417905
YWHAE Epilepsy-associated gene Nedd4-2 mediates neuronal activity and seizure susceptibility through AMPA receptors PLoS Genet 2017 Protein TP300245
YWHAZ The proteome of human Fallopian tube lavages during the phase of embryo transit reveals candidate proteins for the optimization of preimplantation embryo culture Human reproduction (Oxford, England) 2020 Protein TP326999
YY1 Transcriptional regulation of human abraxas brother protein 1 expression by yin yang 1 Biochem. Cell Biol. 2020 Protein TP721191
ZC3H12A MCPIP1 reduces HBV-RNA by targeting its epsilon structure Scientific reports 2020 Protein TP301381
ZFYVE21 ZFYVE21 is a complement-induced Rab5 effector that activates non-canonical NF-κB via phosphoinosotide remodeling of endosomes Nat Commun 2019 Protein TP303337
ZNF148 Functional characterization of a multi-cancer risk locus on chr5p15.33 reveals regulation of TERT by ZNF148 Nat Commun 2017 Protein TP602963
ZNF750 ZNF750 interacts with KLF4 and RCOR1, KDM1A, and CTBP1/2 chromatin regulators to repress epidermal progenitor genes and induce differentiation genes Genes Dev. Sep 2014 Protein TP760460