Protein Citations

OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.

Search citations by gene symbols or target names

Here are some of the recent papers making use of OriGene products by fellow researchers.

Target Research Paper Journal Product SKU
ARID4B is a good biomarker to predict tumour behaviour and decide WHO grades in gliomas and meningiomas J. Clin. Pathol. 2016 Protein LY500001
CDT1 Human replication licensing factor Cdt1 directly links mitotic kinetochores to spindle microtubules bioRxiv 2017 Protein TP301657
NCL Human CCDC47 sandwich immunoassay development with electrochemiluminescence technology J. Immunol. Methods 2017 Protein TP319082
ACO1 An Investigation of the Effect of MN2+ on the FTH1 IRE-IRP Complex Thesis May 2015 Protein TP301857
ACTA2 Phosphoglycerate mutase 1 promotes cancer cell migration independent of its metabolic activity Oncogene 2016 Protein TP327802
ACTN4 Alpha-Actinin-4 is a Possible Target Protein for Aristolochic Acid I in Human Kidney Cells In Vitro Am. J. Chin. Med. Apr 2016 Protein TP302873
AGO2 An alternative microRNA-mediated post-transcriptional regulation of GADD45A by p53 in human non-small-cell lung cancer cells Sci Rep 2017 Protein TP328592
AGTR1 Dopamine D2 and angiotensin II type 1 receptors form functional heteromers in rat striatum Biochem. Pharmacol. May 2015 Protein LY429794
AGTR1 Critical period for dopaminergic neuroprotection by hormonal replacement in menopausal rats Neurobiol. Aging Nov 2014 Protein LY429794
AGTR2 Critical period for dopaminergic neuroprotection by hormonal replacement in menopausal rats Neurobiol. Aging Nov 2014 Protein LY400227
ALDOA Upregulation of the ALDOA/DNA-PK/p53 pathway by dietary restriction suppresses tumor growth Oncogene 2017 Protein TP720179
ALT1 Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity Theranostics, Jan 2014. Protein TP303756
ALT2 Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity Theranostics, Jan 2014. Protein TP309119
AMACR Autoantibodies against oncogenic ERG protein in prostate cancer: potential use in diagnosis and prognosis in a panel with C-MYC, AMACR and HERV-K Gag Genes & Cancer 2016 Protein TP313437
AMBRA1 Ambra1 spatially regulates Src activity and Src/FAK-mediated cancer cell invasion via trafficking networks Elife 2017 Protein TP306255
AMFR Affinity proteomics discovers decreased levels of AMFR in plasma from Osteoporosis patients Proteomics Clin Appl 2016 Protein LY420107
AMFR Affinity proteomics discovers decreased levels of AMFR in plasma from Osteoporosis patients Proteomics Clin Appl 2016 Protein LY420107
AMFR Affinity proteomics discovers decreased levels of AMFR in plasma from Osteoporosis patients Proteomics Clin Appl Feb 2015 Protein LY420107
AMH Anti-mullerian hormone is expressed by endometriosis tissues and induces cell cycle arrest and apoptosis in endometriosis cells J. Exp. Clin. Cancer Res. Jun 2014 Protein TP308397
AMY1A Determination of Molar Mass and Its Relationship with Free Energy of Activation: A Case Study on Human Salivary Alpha Amylase Journal of Scientific Research & Reports 2016 Protein TP317403
ANXA2 Peripheral Blood Monocyte-expressed ANXA2 Gene is Involved in Pathogenesis of Osteoporosis in Humans Mol. Cell. Proteomics, Nov 2011; 10: M111.011700. Protein TP305081
ANXA6 Cytosolic dynamics of annexin A6 triggers feedback regulation of hypertrophy via atrial natriuretic peptide in cardiomyocytes J. Biol. Chem., Jan 2014. Protein LY400463
APEX1 Inhibition of hydrogen sulfide biosynthesis sensitizes lung adenocarcinoma to chemotherapeutic drugs by inhibiting mitochondrial DNA repair and suppressing cellular bioenergetics. Sci Rep 2016 Protein TP720082
APOA2 PI(4,5)P2 Is Translocated by ABCA1 to the Cell Surface Where It Mediates Apolipoprotein A1 Binding and Nascent HDL Assembly. Circ. Res. 2016 Protein TP721104
APOBEC3G The double-domain cytidine deaminase APOBEC3G is a cellular site-specific RNA editing enzyme Sci Rep 2016 Protein LY411904
APOC2 Static and turnover kinetic measurement of protein biomarkers involved in triglyceride metabolism including apoB48 and apoA5 by LC-MS/MS J. Lipid Res. April 2014 Protein TP302771
APOC3 Apolipoprotein C-III in the high-density lipoprotein proteome of cerebral lacunar infarction patients impairs its anti-inflammatory function International Journal of Molecular Medicine 2017 Protein TP306566
APOC3 Static and turnover kinetic measurement of protein biomarkers involved in triglyceride metabolism including apoB48 and apoA5 by LC-MS/MS J. Lipid Res. April 2014 Protein TP306566
APOE PI(4,5)P2 Is Translocated by ABCA1 to the Cell Surface Where It Mediates Apolipoprotein A1 Binding and Nascent HDL Assembly. Circ. Res. 2016 Protein TP723016
APOE Static and turnover kinetic measurement of protein biomarkers involved in triglyceride metabolism including apoB48 and apoA5 by LC-MS/MS J. Lipid Res. April 2014 Protein TP300395
APP Chemoproteomic Profiling of Acetanilide Herbicides Reveals Their Role in Inhibiting Fatty Acid Oxidation ACS Chem. Biol 2017 Protein TP309575
APP Specific Amyloid ß Clearance by a Catalytic Antibody Construct J. Biol. Chem. Feb 2015 Protein TP309575
AQP3 Effects of Recombinant Aquaporin 3 and Seawater Acclimation on the Expression of Aquaporin 3 and 8 mRNAs in the Parr and Smolt Stages of Rainbow Trout, Oncorhynchus mykiss Ocean and Polar Research 2016 Protein TP301856
AQP3 Profiles of hypothalamus-pituitary-interrenal axis gene expression in the parr and smolt stages of rainbow trout, Oncorhynchus mykiss: Effects of recombinant aquaporin 3 and seawater acclimation Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. Dec 2014 Protein TP301856
ASAP1 Antibodies Directed against a Peptide Epitope of a Klebsiella pneumoniae-Derived Protein Are Present in Ankylosing Spondylitis PLoS ONE 2017 Protein LY413020
ASRGL1 Loss of ASRGL1 expression is an independent biomarker for disease-specific survival in endometrioid endometrial carcinoma Gynecol. Oncol. Apr 2015 Protein LY421255
ATF2 Novel Noncatalytic Substrate-Selective p38α-Specific MAPK Inhibitors with Endothelial-Stabilizing and Anti-Inflammatory Activity J. Immunol 2017 Protein TP710017
AXIN1 Small-molecule binding of the axin RGS domain promotes ß-catenin and Ras degradation Nat. Chem. Biol. Jun 2016 Protein TP308349
BCL2L1 Pan-Cancer Analysis Links PARK2 to BCL-XL-Dependent Control of Apoptosis. Neoplasia 2016 Protein TP301314
BDNF U6 snRNA is a Suitable Endogenous Control for microRNA-124 and-134 in Cultured Rat Hippocampal Neurons Sains Malaysiana Jul 2015 Protein TP723035
BECN1 Cytosolic HMGB1 controls the cellular autophagy/apoptosis checkpoint during inflammation J. Clin. Invest. Mar 2015 Protein TP301629
Beta-catenin Phosphorylation of E-cadherin at threonine 790 by protein kinase Cd reduces ß-catenin binding and suppresses the function of E-cadherin Oncotarget 2016 Protein TP308947
BMI1 BMI1, a new target of CK2α Mol. Cancer 2017 Protein TP760041
BMP2 Overexpression of colorectal cancer oncogene CHRDL2 predicts a poor prognosis Oncotarget 2017 Protein TP750012
BPIFA1 Anti-BPIFA1/SPLUNC1: A new autoantibody prevalent in patients with endstage cystic fibrosis Journal of Cystic Fibrosis 23 October 2013 Protein TP313322
BRAF Newly Identified BRAF Mutation in Rheumatoid Arthritis. Arthritis & rheumatology (Hoboken, N.J.) 2016 Protein TP700031
BTN3A2 Structural and functional diversity of metalloproteinases encoded by the Bacteroides fragilis pathogenicity island FEBS J. April 2014 Protein TP301183
BTN3A2 Butyrophilin 3A1 Plays an Essential Role in Prenyl Pyrophosphate Stimulation of Human V{gamma}2V{delta}2 T Cells J. Immunol., Aug 2013; 191: 1029 - 1042. Protein TP301183
C21orf56 Antibody-based Protein Profiling of the Human Chromosome 21 Mol. Cell. Proteomics, Mar 2012; 11: M111.013458. Protein TP324562
C21orf59 Antibody-based Protein Profiling of the Human Chromosome 21 Mol. Cell. Proteomics, Mar 2012; 11: M111.013458. Protein TP300169
calgranulin B Antitumor effects of calgranulin B internalized in human colon cancer cells Oncotarget 2016 Protein TP308250
CALR Anti-Peptide Monoclonal Antibodies Generated for Immuno-Multiple Reaction Monitoring-Mass Spectrometry Assays Have a High Probability of Supporting Western blot and ELISA Mol. Cell Proteomics Feb 2015 Protein LY401384
CAPN1 Early to Intermediate Steps of Tumor Embolic Formation Involve Specific Proteolytic Processing of E-Cadherin Regulated by Rab7 Mol. Cancer Res., Jun 2012; 10: 713 - 726. Protein LY400662
CAPN2 Distinct Roles forµ-Calpain and m-Calpain in Synaptic NMDAR-Mediated Neuroprotection and Extrasynaptic NMDAR-Mediated Neurodegeneration J. Neurosci. 18880-92 Nov 2013 Protein TP305642
CAPN2 Calpain-2-Mediated PTEN Degradation Contributes to BDNF-Induced Stimulation of Dendritic Protein Synthesis J. Neurosci., Mar 2013; 33: 4317 - 4328. Protein TP305642
CAPN2 Early to Intermediate Steps of Tumor Embolic Formation Involve Specific Proteolytic Processing of E-Cadherin Regulated by Rab7 Mol. Cancer Res., Jun 2012; 10: 713 - 726. Protein TP305642
CAPRIN1 Stress Granules Regulate Double-Stranded RNA-Dependent Protein Kinase Activation through a Complex Containing G3BP1 and Caprin1 MBio Mar 2015 Protein TP300300
CCL16 Possible Roles of CC- and CXC-Chemokines in Regulating Bovine Endometrial Function during Early Pregnancy. Int J Mol Sci 2017 Protein TP723266
CCL5 Galectin-3 captures interferon-gamma in the tumor matrix reducing chemokine gradient production and T-cell tumor infiltration Nat Commun 2017 Protein TP303799
CD274 The prognostic role of immune checkpoint markers programmed cell death protein 1 (PD-1) and programmed death ligand 1 (PD-L1) in a large, multicenter prostate cancer cohort oncotarget 2016 Protein LY415473
CD274 Assessing PD-L1 and PD-1 in Non-Small Cell Lung Cancer (NSCLC): a Novel Immunoscore Approach Clinical Lung Cancer 2016 Protein LY415473
CD33 Mono- and dual-targeting triplebodies activate natural killer cells and have anti-tumor activity in vitro and in vivo against chronic lymphocytic leukemia Oncoimmunology 2016 Protein TP307023
CD33 Mono-and dual-targeting triplebodies activate natural killer cells and have anti-tumor activity in vitro and in vivo against chronic lymphocytic leukemia OncoImmunology 2016 Protein TP307023
CD44 A CD44 specific peptide developed by phage display for targeting gastric cancer Biotechnol. Lett. Jul 2015 Protein TP321771
CD44 Anti-Peptide Monoclonal Antibodies Generated for Immuno-Multiple Reaction Monitoring-Mass Spectrometry Assays Have a High Probability of Supporting Western blot and ELISA Mol. Cell Proteomics Feb 2015 Protein LY400203
CD70 Insights into the molecular basis of a bispecific antibody's target selectivity MAbs Mar 2015 Protein TP300410
CD81 Exosomal biomarkers of brain insulin resistance associated with regional atrophy in Alzheimer's disease Hum Brain Mapp 2017 Protein TP317508
CD81 Decreased synaptic proteins in neuronal exosomes of frontotemporal dementia and Alzheimer's disease FASEB J.2016 Protein TP317508
CD81 Cargo proteins of plasma astrocyte-derived exosomes in Alzheimer's disease. FASEB J. 2016 Protein TP317508
CD81 Prediction of conversion from mild cognitive impairment to dementia with neuronally derived blood exosome protein profile Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring May 2016 Protein TP317508
CD81 Dysfunctionally phosphorylated type 1 insulin receptor substrate in neural-derived blood exosomes of preclinical Alzheimer's disease FASEB J. Oct 2014 Protein TP317508
CD81 Identification of preclinical Alzheimer's disease by a profile of pathogenic proteins in neurally derived blood exosomes: A case-control study Alzheimers Dement Aug 2014 Protein TP317508
CD84 A 3 base pair deletion in TBX1 leads to reduced protein expression and transcriptional activity Sci Rep 2017 Protein LY9
CD9 Autoantibodies to tetraspanins (CD9, CD81 and CD82) in demyelinating diseases Journal of Neuroimmunology Feb 2016 Protein TP302000
CDCP1 Identification of anti-tumour biologics using primary tumour models, 3-D phenotypic screening and image-based multi-parametric profiling Mol. Cancer Aug 2015 Protein TP320633
CDH3 Identification of Putative Immunologic Targets for Colon Cancer Prevention Based on Conserved Gene Upregulation from Preinvasive to Malignant Lesions Cancer Prevention Research, Jul 2013; 6: 666 - 674. Protein TP307346
CDK2AP2 Proteome-wide epitope mapping of antibodies using ultra-dense peptide arrays Mol. Cell Proteomics. April 2014 Protein LY417039
CDKN1A Cyclin-dependent kinase 8 mediates chemotherapy-induced tumor-promoting paracrine activities PNAS, Aug 2012; 109: 13799 - 13804. Protein TP301765
CDYL Tubulin acetylation: A novel functional avenue for CDYL in sperm Cytoskeleton (Hoboken) 2017 Protein LY406868
CFL2 Fatigue-Related Gene Networks Identified in CD14+ Cells Isolated From HIV-Infected Patients—Part I: Research Findings Biol Res Nurs, Apr 2013; 15: 137 - 151. Protein LY429663
CHI3L1 Chitinase 3-like 1: prognostic biomarker in clinically isolated syndromes Brain Feb 2015 Protein TP303769
CHRDL2 Overexpression of colorectal cancer oncogene CHRDL2 predicts a poor prognosis Oncotarget 2017 Protein TP320245
CIRBP Cold-inducible RNA-binding protein (CIRP) triggers inflammatory responses in hemorrhagic shock and sepsis J. Bacteriol., Aug 2013; 195: 3468 - 3475. Protein TP301639
CLEC4E Fungal engagement of the C-type lectin mincle suppresses dectin-1-induced antifungal immunity Cell Host Microbe 494-505 15 4. April 2014 Protein TP300244
CLIC2 Association of anti-CLIC2 and anti-HMGB1 autoantibodies with higher disease activity in systemic lupus erythematosus patients J Postgrad Med 2017 Protein TP304727
CLU PEGylated-Nanoliposomal Clusterin for Amyloidogenic Light Chain-Induced Endothelial Dysfunction J Liposome Res 2017 Protein TP311875
CLU Anti-Peptide Monoclonal Antibodies Generated for Immuno-Multiple Reaction Monitoring-Mass Spectrometry Assays Have a High Probability of Supporting Western blot and ELISA Mol. Cell Proteomics Feb 2015 Protein LY433124
CMPK1 Selective Phosphorylation of South and North-Cytidine and Adenosine Methanocarba-Nucleosides by Human Nucleoside and Nucleotide Kinases Correlates with Their Growth Inhibitory Effects on Cultured Cells Nucleosides Nucleotides Nucleic Acids Aug 2015 Protein TP304856
CNN2 Calponin-h2: a potential serum marker for the early detection of human breast cancer? Tumour Biol. Aug 2014 Protein TP321104
CNP Schwann Cells Metabolize Extracellular 2',3'-cAMP to 2'-AMP J. Pharmacol. Exp. Ther. May 2015 Protein TP307038
CORIN Sensitive and low-background electrochemical assay of corin activity via supramolecular recognition and rolling circle amplification Anal. Chim. Acta May 2016 Protein TP312742
CPAMD8 Morgagnian cataract resulting from a naturally occurring nonsense mutation elucidates a role of CPAMD8 in mammalian lens development PLoS ONE 2017 Protein LY414386
CPNE7 CPNE7, a preameloblast-derived factor, regulates odontoblastic differentiation of mesenchymal stem cells Biomaterials Oct 2014 Protein TP306428
CRABP2 Dissecting antibodies with regards to linear and conformational epitopes PLoS ONE Mar 2015 Protein LY419677
CRMP1 Autism-specific maternal autoantibodies recognize critical proteins in developing brain Translational Psychiatry 3, e277 doi:10.1038/tp.2013.50 Protein TP300483
CRMP2 Autism-specific maternal autoantibodies recognize critical proteins in developing brain Translational Psychiatry 3, e277 doi:10.1038/tp.2013.50 Protein LY419992
CSRP3 Aberrant Glycosylation in the Left Ventricle and Plasma of Rats with Cardiac Hypertrophy and Heart Failure PLoS ONE Jun 2016 Protein TP325217
CTAG1B Case-Control Study: Smoking History Affects the Production of Tumor Antigen-Specific Antibodies NY-ESO-1 in Patients with Lung Cancer in Comparison with Cancer Disease-Free Group J Thorac Oncol 2016 Protein TP313318
CTAG1B Expression of tumor antigens on primary ovarian cancer cells compared to established ovarian cancer cell lines Oncotarget 2016 Protein TP313318
CTBP1 ZNF750 interacts with KLF4 and RCOR1, KDM1A, and CTBP1/2 chromatin regulators to repress epidermal progenitor genes and induce differentiation genes Genes Dev. Sep 2014 Protein TP310529
CTBP2 ZNF750 interacts with KLF4 and RCOR1, KDM1A, and CTBP1/2 chromatin regulators to repress epidermal progenitor genes and induce differentiation genes Genes Dev. Sep 2014 Protein TP324861
CTLA4 CTLA-4 expression in the non-small cell lung cancer patient tumor microenvironment: diverging prognostic impact in primary tumors and lymph node metastases Cancer Immunol. Immunother. 2017 Protein LY417438
CTTN Diagnostic utility of cortactin antibodies in myasthenia gravis Ann. N. Y. Acad. Sci.2017 Protein TP301111
CTTN Clinical Characteristics of Patients With Double-Seronegative Myasthenia Gravis and Antibodies to Cortactin JAMA Neurol 2016 Protein TP301111
CTTN Cortactin autoantibodies in myasthenia gravis Autoimmun Rev Sep 2014 Protein TP301111
CTTN Identification of a novel myositis-associated antibody directed against cortactin Autoimmunity Reviews Aug 2014 Protein TP301111
CYLD CaMKII Mediates Recruitment and Activation of the Deubiquitinase CYLD at the Postsynaptic Density PLoS ONE Mar 2014 Protein TP304099
CYP19A1 Prognostic relevance of estrogen receptor a, ß and aromatase expression in non-small cell lung cancer Steroids May 2016 Protein LY400031
CYTL1 Salvianolic acid B regulates gene expression and promotes cell viability in chondrocytes J. Cell. Mol. Med 2017 Protein TP306778
DAXX PTEN regulates glioblastoma oncogenesis through chromatin-associated complexes of DAXX and histone H3.3 Nat Commun 2017 Protein TP326603
DCTN2 Early Cytoskeletal Protein Modifications Precede Overt Structural Degeneration in the DBA/2J Mouse Model of Glaucoma Front Neurosci 2016 Protein TP314771
DCTN2 Early Cytoskeletal Protein Modifications Precede Overt Structural Degeneration in the DBA/2J Mouse Model of Glaucoma Front Neurosci 2016 Protein TP314771
DDX1 A HIV-1 Tat mutant protein disrupts HIV-1 Rev function by targeting the DEAD-box RNA helicase DDX1 Retrovirology Dec 2014 Protein TP308769
DDX3X A HIV-1 Tat mutant protein disrupts HIV-1 Rev function by targeting the DEAD-box RNA helicase DDX1 Retrovirology Dec 2014 Protein TP304171
DDX5 Resveratrol directly targets DDX5 resulting in suppression of the mTORC1 pathway in prostate cancer Cell Death Dis May 2016 Protein TP300371
DDX5 A Novel Anti-Cancer Agent, 1-(3, 5-Dimethoxyphenyl)-4-[(6-fluoro-2-methoxyquinoxalin-3-yl)aminocarbonyl] piperazine (RX-5902),Interferes with ß-Catenin Function through Y593 phospho-p68RNA Helicase J. Cell. Biochem. Feb 2015 Protein TP300371
DHODH Dihydroorotate dehydrogenase (DHODH) inhibitors affect ATP depletion, endogenous ROS and mediate S-phase arrest in breast cancer cells Biochimie 2017 Protein TP309034
DHODH Inhibition of Dihydroorotate Dehydrogenase Overcomes Differentiation Blockade in Acute Myeloid Leukemia Cell Protein TP309034
DHODH Inhibition of Dihydroorotate Dehydrogenase Overcomes Differentiation Blockade in Acute Myeloid Leukemia Cell 2016 Protein TP309034
DICER1 Dicer interacts with SIRT7 and regulates H3K18 deacetylation in response to DNA damaging agents Nucleic Acids Res. Dec 2015 Protein TP319214
DIRAS3 CDK5 Regulates Paclitaxel Sensitivity in Ovarian Cancer Cells by Modulating AKT Activation, p21Cip1- and p27Kip1-Mediated G1 Cell Cycle Arrest and Apoptosis PLoS ONE Jul 2015 Protein TP302787
DISC1 Disrupted-in-Schizophrenia-1 Attenuates Amyloid-ß Generation and Cognitive Deficits in APP/PS1 Transgenic Mice by Reduction of ß-Site APP-Cleaving Enzyme 1 Levels Neuropsychopharmacology 2016 Protein TP312015
DKK1 Shared gene expression patterns in mesenchymal progenitors derived from lung and epidermis in pulmonary arterial hypertension: identifying key pathways in pulmonary vascular disease Pulm Circ 2016 Protein TP723065
DNM1L Protective Role of PGC-1a in Diabetic Nephropathy Is Associated with the Inhibition of ROS through Mitochondrial Dynamic Remodeling PLoS ONE Apr 2015 Protein TP321708
DNMT3A DNA G-quadruplexes show strong interaction with DNA methyltransferases in vitro FEBS Lett. 2016 Protein TP313064
DNMT3B DNA G-quadruplexes show strong interaction with DNA methyltransferases in vitro FEBS Lett. 2016 Protein TP323206
E2F1 Recruitment of Pontin/Reptin by E2f1 amplifies E2f transcriptional response during cancer progression Nat Commun Dec 2015 Protein TP308247
E2F3 Recruitment of Pontin/Reptin by E2f1 amplifies E2f transcriptional response during cancer progression Nat Commun Dec 2015 Protein TP760363
EBI3 A novel IL-23p19/Ebi3 (IL-39) cytokine mediates inflammation in Lupus-like mice Eur. J. Immunol. Mar 2016 Protein TP723851
EEF1A1 Specific Interaction between eEF1A and HIV RT Is Critical for HIV-1 Reverse Transcription and a Potential Anti-HIV Target PLoS Pathog. Dec 2015 Protein TP309697
EEF1A1 The Level of Autoantibodies Targeting Eukaryote Translation Elongation Factor 1 a1 and Ubiquitin-Conjugating Enzyme 2L3 in Nondiabetic Young Adults Diabetes Metab J Nov2015 Protein TP309697
EEF1A1 Identification of Novel Autoantibodies in Type 1 Diabetic Patients Using a High-Density Protein Microarray Diabetes Jun 2014 Protein TP309697
EEF1B2 Specific Interaction between eEF1A and HIV RT Is Critical for HIV-1 Reverse Transcription and a Potential Anti-HIV Target PLoS Pathog. Dec 2015 Protein TP321264
EEF1D Specific Interaction between eEF1A and HIV RT Is Critical for HIV-1 Reverse Transcription and a Potential Anti-HIV Target PLoS Pathog. Dec 2015 Protein TP303202
EEF1G Specific Interaction between eEF1A and HIV RT Is Critical for HIV-1 Reverse Transcription and a Potential Anti-HIV Target PLoS Pathog. Dec 2015 Protein TP319578
EFEMP1 Novel paracrine modulation of Notch-DLL4 signaling by fibulin-3 promotes angiogenesis in high-grade gliomas Cancer Res. Aug 2014 Protein TP314953
Eg5 APC/C is an essential regulator of centrosome clustering Nat Commun 3686 5 . April 2014 Protein TP318842
EGFL7 EGFL7 is expressed in bone microenvironment and promotes angiogenesis via ERK, STAT3, and integrin signaling cascades J. Cell. Physiol. Jun 2014 Protein TP723072
EGFR Inhibition of triple-negative and Herceptin-resistant breast cancer cell proliferation and migration by Annexin A2 antibodies Br. J. Cancer Oct 2014 Protein TP710003
EGLN2 The LINK-A lncRNA activates normoxic HIF1 [alpha] signalling in triple-negative breast cancer Nature cell biology Jan 2016 Protein TP306152
EIF2AK3 Human GRP78 affinity towards its signaling partners Ire1α and PERK is differently modulated by an unfolded protein client Biochem. Biophys. Res. Commun. 2017 Protein TP314993
EIF4G1 DAP5 associates with eIF2ß and eIF4AI to promote Internal Ribosome Entry Site driven translation Nucleic Acids Res. Mar 2015 Protein TP312877
ELAVL1 Oncogenic p95HER2 regulates Na+-HCO3- cotransporter NBCn1 mRNA stability in breast cancer cells via 3'UTR dependent processes Biochem. J. 2016 Protein TP301562
ELAVL1 Tissue-specific control of brain-enriched miR-7 biogenesis Genes & Dev., Jan 2013; 27: 24 - 38. Protein TP301562
ELAVL4 The DPYSL2 gene connects mTOR and schizophrenia Transl Psychiatry 2016 Protein TP318612
ELF1 SDHD promoter mutations ablate GABP transcription factor binding in melanoma Cancer Res 2017 Protein TP760629
ELF1 An interaction proteomics survey of transcription factor binding at recurrent TERT promoter mutations Proteomics Nov 2015 Protein TP760629
ENGASE Repurposing of Proton Pump Inhibitors as first identified small molecule inhibitors of endo-β-N-acetylglucosaminidase (ENGase) for the treatment of NGLY1 deficiency, a rare genetic disease Bioorg. Med. Chem. Lett. 2017 Protein TP311494
EP300 An Ultraconserved Brain-specific Enhancer within ADGRL3 (LPHN3) Underpins ADHD Susceptibility Biological Psychiatry 2016 Protein TP710007
EPRS Identification of a gamma interferon-activated inhibitor of translation-like RNA motif at the 3' end of the transmissible gastroenteritis coronavirus genome modulating innate immune response MBio Mar 2015 Protein TP317559
ERBB2 Expression of tumor antigens on primary ovarian cancer cells compared to established ovarian cancer cell lines Oncotarget 2016 Protein TP312583
ERBB2 Anti-Peptide Monoclonal Antibodies Generated for Immuno-Multiple Reaction Monitoring-Mass Spectrometry Assays Have a High Probability of Supporting Western blot and ELISA Mol. Cell Proteomics Feb 2015 Protein LY417979
ERBB2 Anti-Peptide Monoclonal Antibodies Generated for Immuno-Multiple Reaction Monitoring-Mass Spectrometry Assays Have a High Probability of Supporting Western blot and ELISA Mol. Cell Proteomics Feb 2015 Protein LY423666
ERG Autoantibodies against oncogenic ERG protein in prostate cancer: potential use in diagnosis and prognosis in a panel with C-MYC, AMACR and HERV-K Gag Genes Cancer 2016 Protein TP308093
ERG Autoantibodies against oncogenic ERG protein in prostate cancer: potential use in diagnosis and prognosis in a panel with C-MYC, AMACR and HERV-K Gag Genes & Cancer 2016 Protein TP308093
ERG Analytical platform evaluation for quantification of ERG in prostate cancer using protein and mRNA detection methods Journal of Translational Medicine Jan 2015 Protein TP308093
ERN1 Human GRP78 affinity towards its signaling partners Ire1α and PERK is differently modulated by an unfolded protein client Biochem. Biophys. Res. Commun. 2017 Protein TP315023
ERN1 Hypothermia and Rewarming Activate a Macroglial Unfolded Protein Response Independent of Hypoxic-Ischemic Brain Injury in Neonatal Piglets Dev. Neurosci. 2016 Protein TP315023
ESR1 A Novel High Throughput Screening Assay for Binding Affinities of Perfluoroalkyl Iodide for Estrogen Receptor Alpha and Beta Isoforms Talanta 2017 Protein TP313277
ESR1 Prognostic relevance of estrogen receptor a, ß and aromatase expression in non-small cell lung cancer Steroids May 2016 Protein LY400046
ESR2 A Novel High Throughput Screening Assay for Binding Affinities of Perfluoroalkyl Iodide for Estrogen Receptor Alpha and Beta Isoforms Talanta 2017 Protein TP710031
ESR2 Prognostic relevance of estrogen receptor a, ß and aromatase expression in non-small cell lung cancer Steroids May 2016 Protein LY425704
ESRRG Antimitotic activity of DY131 and the estrogen-related receptor beta 2 (ERRβ2) splice variant in breast cancer Oncotarget 2016 Protein TP312143
ESRRG ERRß Splice Variants Differentially Regulate Cell Cycle Progression Cell Cycle Dec 2014 Protein TP312143
EWSR1 Liquid demixing of intrinsically disordered proteins is seeded by poly(ADP-ribose) Nat Commun Aug 2015 Protein TP303709
EZH2 SKP2 loss destabilizes EZH2 by promoting TRAF6-mediated ubiquitination to suppress prostate cancer Oncogene 2016 Protein TP302054
EZH2 Antisense RNA-Mediated Epigenetic Regulation of Brain-Derived Neurotrophic Factor Thesis Dec2015 Protein TP302054
EZH2 Screening for Small-Molecule Modulators of Long Noncoding RNA-Protein Interactions Using AlphaScreen J Biomol Screen Jul 2015 Protein TP302054
EZR A prospective study of autoantibodies to Ezrin and pancreatic cancer risk Cancer Causes Control Jun 2016 Protein TP300404
EZR Are ERM (ezrin/radixin/moesin) proteins targets for autoantibodies in demyelinating neuropathies? Hum. Immunol. Oct 2014 Protein TP300404
FAM84A Distinct oligoclonal band antibodies in multiple sclerosis recognize ubiquitous self-proteins Proc. Natl. Acad. Sci. U.S.A. Jun 2016 Protein TP308623
FBLN5 LTBP-2 competes with tropoelastin for binding to fibulin-5 and heparin, and is a negative modulator of elastinogenesis Matrix Biol. 2013 Oct 19. pii: S0945-053X(13)00136-4. doi: 10.1016 Protein TP304683
FCER1A Antibody to FceRIa Suppresses Immunoglobulin E Binding to High-Affinity Receptor I in Allergic Inflammation Yonsei Med. J. 2016 Protein LY400730
FCGRT Utility of a human FcRn transgenic mouse model in drug discovery for early assessment and prediction of human pharmacokinetics of monoclonal antibodies MAbs 2016 Protein TP300364
FCGRT Quantitative analysis of human neonatal Fc receptor (FcRn) tissue expression in transgenic mice by online peptide immuno-affinity LC-HRMS Anal. Chem. Mar 2016 Protein TP300364
FGF2 Pluripotent stem cells induced from mouse neural stem cells and small intestinal epithelial cells by small molecule compounds Cell Res. Dec 2015 Protein TP750002
FGF2 Small-Molecule-Driven Direct Reprogramming of Mouse Fibroblasts into Functional Neurons Cell Stem Cell Aug 2015 Protein TP750002
FGF2 Pluripotent stem cells induced from mouse somatic cells by small-molecule compounds. Science. 2013 Aug 9;341(6146):651-4. doi: 10.1126/science.1239278. Protein TP750002
FHL1 Development of autoantibodies against muscle-specific FHL1 in severe inflammatory myopathies J. Clin. Invest. Nov 2015 Protein TP303478
FLNA S6K is a morphogenic protein with a mechanism involving Filamin-A phosphorylation and phosphatidic acid binding FASEB J. Dec 2014 Protein TP326488
FMOD Melanocyte pigmentation inversely correlates with MCP-1 production and angiogenesis-inducing potential FASEB J. Nov 2014 Protein TP306534
FOLR2 Growing Mouse Oocytes Transiently Activate Folate Transport via Folate Receptors As They Approach Full Size Biol. Reprod. Apr 2016 Protein LY400280
FOXO1 Cellular hormetic response to 27-hydroxycholesterol promotes neuroprotection through AICD induction of MAST4 abundance and kinase activity Sci Rep 2017 Protein TP300477
FOXO3 Histone deacetylase 3 associates with MeCP2 to regulate FOXO and social behavior Nat. Neurosci. 2016 Protein TP302894
FOXO3 FOXO3-NF-?B RelA Protein Complexes Reduce Proinflammatory Cell Signaling and Function J. Immunol. Nov 2015 Protein TP309846
Foxp3 Functional characterization of Foxp3-specific spontaneous immune responses Leukemia doi:10.1038/leu.2013.196 Protein TP317580
FUBP1 FUBP1: a new protagonist in splicing regulation of the DMD gene Nucleic Acids Res. Feb 2015 Protein TP315674
FUS Comparative interactomics analysis of different ALS-associated proteins identifies converging molecular pathways Acta Neuropathol. May 2016 Protein TP301808
FUS Liquid demixing of intrinsically disordered proteins is seeded by poly(ADP-ribose) Nat Commun Aug 2015 Protein TP301808
FUS ALS-associated mutations in FUS disrupt the axonal distribution and function of SMN Hum. Mol. Genet., May 2013; 10.1093/hmg/ddt222. Protein TP301808
G0S2 G0/G1 Switch Gene 2 controls adipose triglyceride lipase activity and lipid metabolism in skeletal muscle Molecular Metabolism Apr 2016 Protein TP302063
G6PD Aspirin inhibits glucose-6-phosphate dehydrogenase activity in HCT 116 cells through acetylation: Identification of aspirin-acetylated sites Mol Med Rep 2016 Protein TP320625
GATA3 Transactivation of human osteoprotegerin promoter by GATA-3 Sci Rep Jul 2015 Protein TP301618
Gemin5 The RNA-binding protein Gemin5 binds directly to the ribosome and regulates global translation Nucleic Acids Res. 2016 Protein TP317516
GFPT2 Glutamine–Fructose-6-Phosphate Transaminase 1, 2 (GFPT1, 2) Handbook of Glycosyltransferases and Related Genes, Jan 2014. Protein LY417501
GLI1 Identification of a DYRK1A-mediated phosphorylation site within the nuclear localization sequence of the hedgehog transcription factor GLI1 Biochem. Biophys. Res. Commun. 2017 Protein TP301110
GPNMB The LINK-A lncRNA activates normoxic HIF1 [alpha] signalling in triple-negative breast cancer Nature cell biology Jan 2016 Protein TP307615
GPR4 Short-chain fatty acids and acidic pH up-regulate UT-B, GPR41, and GPR4 in rumen epithelial cells of goats Am. J. Physiol. Regul. Integr. Comp. Physiol. Dec 2014 Protein LY401625
GPR56 Proteome-wide epitope mapping of antibodies using ultra-dense peptide arrays Mol. Cell Proteomics. April 2014 Protein LY428998
GRB10 Antigen-specificity of antiretinal antibodies in patients with noninfectious uveitis Canadian Journal of Ophthalmology / Journal Canadien d'Ophtalmologie 2017 Protein TP306853
GRIA1 Epilepsy-associated gene Nedd4-2 mediates neuronal activity and seizure susceptibility through AMPA receptors PLoS Genet 2017 Protein TP326253
GRINL1A Primary Central Nervous System (CNS) Lymphoma B Cell Receptors Recognize CNS Proteins J. Immunol. Aug 2015 Protein TP319621
GSK3A Direct High Affinity Interaction between Aß42 and GSK3a Stimulates Hyperphosphorylation of Tau. A New Molecular Link in Alzheimer's Disease? ACS Chem Neurosci Dec 2015 Protein TP308698
GZMK Antigen-specificity of antiretinal antibodies in patients with noninfectious uveitis Canadian Journal of Ophthalmology / Journal Canadien d'Ophtalmologie 2017 Protein LY419525
HDAC4 PARP1 Mediates LPS-Induced HMGB1 Release by Macrophages through Regulation of HMGB1 Acetylation J. Immunol. Nov 2014 Protein TP311495
HEK293 cell lysate LAG-3 in non-small cell lung cancer: expression in primary tumors and metastatic lymph nodes is associated with improved survival Clinical Lung Cancer 2017 Protein LY500001
HER-2/neu Case-Control Study: Smoking History Affects the Production of Tumor Antigen-Specific Antibodies NY-ESO-1 in Patients with Lung Cancer in Comparison with Cancer Disease-Free Group J Thorac Oncol 2016 Protein TP312583
HGF PAX2 promoted prostate cancer cell invasion through transcriptional regulation of HGF in an in vitro model Biochim. Biophys. Acta Aug 2015 Protein TP315593
HLA-G1 Soluble factors derived from human amniotic epithelial cells suppress collagen production in human hepatic stellate cells Cytotherapy Mar 2014 Protein TP305216
HMGB1 Association of anti-CLIC2 and anti-HMGB1 autoantibodies with higher disease activity in systemic lupus erythematosus patients J Postgrad Med 2017 Protein TP720309
HNF4A Hepatocyte nuclear factor (HNF) 4a transactivation of cytochrome P450 (Cyp) 2d40 promoter is enhanced during pregnancy in mice Biochem. Pharmacol. Jan 2015 Protein TP317863
HNRNPA1 HNRNPA1 interacts with a 5'-flanking distal element of interleukin-6 and upregulates its basal transcription Genes and Immunity doi:10.1038/gene.2013.41 Protein TP303314
HNRNPA2B1 The cellular protein hnRNP A2/B1 enhances HIV-1 transcription by unfolding LTR promoter G-quadruplexes Sci Rep 2017 Protein TP319318
HNRNPM Heterogeneous nuclear ribonucleoprotein M facilitates enterovirus infection J. Virol. Apr 2015 Protein TP760393
HSPA5 HSPA5 negatively regulates lysosomal activity through ubiquitination of MUL1 in head and neck cancer Autophagy 2017 Protein TP305859
HSPA5 Glucose-regulated protein 78 autoantibody associates with blood-brain barrier disruption in neuromyelitis optica Sci Transl Med 2017 Protein TP305859
HSPA5 Human GRP78 affinity towards its signaling partners Ire1α and PERK is differently modulated by an unfolded protein client Biochem. Biophys. Res. Commun. 2017 Protein TP305859
HSPH1 Extracellular HSP110 skews macrophage polarization in colorectal cancer OncoImmunology Apr 2016 Protein TP307102
HT1011 Epigenetic Regulation of Inflammatory Gene Expression in Macrophages by Selenium The Journal of Nutritoinal Biochemistry Oct 2014 Protein TP790010
HTRA1 HtrA1 Mediated Intracellular Effects on Tubulin Using a Polarized RPE Disease Model EBioMedicine 2017 Protein TP322362
HTRA1 HtrA1 Mediated Intracellular Effects on Tubulin Using a Polarized RPE Disease Model EBioMedicine 2017 Protein TP700208
ID3 PCB153-Induced Overexpression of ID3 Contributes to the Development of Microvascular Lesions PLoS ONE Aug 2014 Protein TP300583
IDE Analysis of the proteolysis of bioactive peptides using a peptidomics approach Nature Protocols 8, 1730-1742 doi:10.1038/nprot.2013.104 Protein TP320700
IDH1 A Highly Facile and Specific Assay for Cancer-Causing Isocitrate Dehydrogenase Mutant Using (13)C4-Labeled a-Ketoglutarate and Heteronuclear NMR Anal. Chem. Dec 2013. Protein TP310582
IFIH1 Neutrophil extracellular traps may contribute to interstitial lung disease associated with anti-MDA5 autoantibody positive dermatomyositis Clin. Rheumatol. 2017 Protein TP315661
IFIH1 Chemokine profiles of interstitial pneumonia in patients with dermatomyositis: a case control study Sci Rep 2017 Protein TP315661
IFIH1 Anti-MDA5 autoantibodies in juvenile dermatomyositis identify a distinct clinical phenotype: a prospective cohort study Arthritis Res. Ther. July 2014 Protein TP315661
IFNG Tripartite Motif-Containing Protein 22 Interacts with Class II Transactivator and Orchestrates Its Recruitment in Nuclear Bodies Containing TRIM19/PML and Cyclin T1 Front Immunol 2017 Protein TP721239
IFT57 BBSome function is required for both the morphogenesis and maintenance of the photoreceptor outer segment PLoS Genet. 2017 Protein LC402637
IGF2BP1 Enhanced CLIP Uncovers IMP Protein-RNA Targets in Human Pluripotent Stem Cells Important for Cell Adhesion and Survival Cell Rep Apr 2016 Protein TP316226
IGFBP5 Apoptosis during embryonic tissue remodeling is accompanied by cell senescence Aging (Albany NY) Nov 2015 Protein TP723173
IL17RD Orphan receptor IL-17RD regulates Toll-like receptor signalling via SEFIR/TIR interactions Nat Commun Mar 2015 Protein TP317198
IL23A Phage-assisted continuous evolution of proteases with altered substrate specificity Nat Commun 2017 Protein TP309680
IL23A A novel IL-23p19/Ebi3 (IL-39) cytokine mediates inflammation in Lupus-like mice Eur. J. Immunol. Mar 2016 Protein TP723221
IL6 Antibody Array Revealed PRL-3 Affects Protein Phosphorylation and Cytokine Secretion PLoS ONE 2017 Protein TP723240
ILK Stabilization of integrin-linked kinase by the Hsp90-CHIP axis impacts cellular force generation, migration and the fibrotic response The EMBO Journal 32, 1409-1424 doi:10.1038/emboj.2013.90 Protein TP320460
INS High Glucose Accelerates Cell Proliferation and Increases the Secretion and mRNA Expression of Osteopontin in Human Pancreatic Duct Epithelial Cells Int J Mol Sci 2017 Protein TP302701
IRF5 Sex Differences in Plasmacytoid Dendritic Cell Levels of IRF5 Drive Higher IFN-a Production in Women J. Immunol. Dec 2015 Protein TP312461
IRF8 Affinity proteomic profiling of plasma, cerebrospinal fluid and brain tissue within multiple sclerosis J. Proteome Res. Sep 2014 Protein LY419485
ITGAL Mutually Exclusive Roles of SHARPIN in Integrin Inactivation and NF-?B Signaling PLoS ONE Nov 2015 Protein TP321297
ITGB2 Mycobacterium tuberculosis Mce3C promotes mycobacteria entry into macrophages through activation of β2 integrin-mediated signalling pathway Cell. Microbiol.2017 Protein TP326157
ITGB2 Mutually Exclusive Roles of SHARPIN in Integrin Inactivation and NF-?B Signaling PLoS ONE Nov 2015 Protein TP326157
JMJD6 Antibody-mediated blockade of JMJD6 interaction with collagen I exerts antifibrotic and antimetastatic activities The FASEB Journal 2017 Protein TP308993
JMJD6 Redistribution of demethylated RNA helicase A during foot-and-mouth disease virus infection: Role of Jumonji C-domain containing protein 6 in RHA demethylation Virology, 3 2014. Protein TP308993
JMJD6 Redistribution of demethylated RNA helicase A during foot-and-mouth disease virus infection: Role of Jumonji C-domain containing protein 6 in RHA demethylation Virology, 3 2014. Protein TP318163
KCNK10 Up-Regulation of TREK-2 Potassium Channels in Cultured Astrocytes Requires De Novo Protein Synthesis: Relevance to Localization of TREK-2 Channels in Astrocytes after Transient Cerebral Ischemia PLoS ONE Apr 2015 Protein LY412052
KDM1A ZNF750 interacts with KLF4 and RCOR1, KDM1A, and CTBP1/2 chromatin regulators to repress epidermal progenitor genes and induce differentiation genes Genes Dev. Sep 2014 Protein TP330555
KEAP1 Ginger Compound [6]-Shogaol and Its Cysteine-Conjugated Metabolite (M2) Activate Nrf2 in Colon Epithelial Cells in Vitro and in Vivo Chem. Res. Toxicol. Sep 2014 Protein TP302189
KEAP1 Identification of UV-protective Activators of Nuclear Factor Erythroid-derived 2-Related Factor 2 (Nrf2) by Combining a Chemical Library Screen with Computer-based Virtual Screening J. Biol. Chem., Sep 2012; 287: 33001 - 33013. Protein TP302189
KIF11 HDAC Inhibitor-Induced Mitotic Arrest Is Mediated by Eg5/KIF11 Acetylation Cell Chem Biol 2017 Protein TP318842
KLF4 Pioneer transcription factors target partial DNA motifs on nucleosomes to initiate reprogramming Cell Apr 2015 Protein TP306691
KLF4 ZNF750 interacts with KLF4 and RCOR1, KDM1A, and CTBP1/2 chromatin regulators to repress epidermal progenitor genes and induce differentiation genes Genes Dev. Sep 2014 Protein TP306691
KMO Development of a Surface Plasmon Resonance Assay for the Characterization of Small-Molecule Binding Kinetics and Mechanism of Binding to Kynurenine 3-Monooxygenase Assay Drug Dev Technol Aug 2015 Protein TP322594
KRAS Selected reaction monitoring approach for validating peptide biomarkers Proc. Natl. Acad. Sci. U.S.A. 2017 Protein TP700052
LACC1 Functional Analyses of the Crohn's Disease Risk Gene LACC1 PLoS ONE 2016 Protein TP307834
LAG3 LAG-3 in non-small cell lung cancer: expression in primary tumors and metastatic lymph nodes is associated with improved survival Clinical Lung Cancer 2017 Protein LY400828
LCP1 L-plastin S-glutathionylation promotes reduced binding to ß-actin and affects neutrophil functions Free Radic. Biol. Med. Apr 2015 Protein TP301670
LECT2 LECT2 induces atherosclerotic inflammatory reaction via CD209 receptor-mediated JNK phosphorylation in human endothelial cells Metab. Clin. Exp. Jun 2015 Protein TP310790
LIG1 Okazaki fragment maturation involves a-segment error editing by the mammalian FEN1/MutSa functional complex EMBO J. Apr 2015 Protein TP310760
LIPC Bioactive lysophospholipids generated by hepatic lipase degradation of lipoproteins lead to complement activation via the classical pathway Invest. Ophthalmol. Vis. Sci. Sep 2014 Protein TP315870
LMNB1 Nuclear matrix metalloproteinase-2 in the cardiomyocyte and the ischemic-reperfused heart J. Mol. Cell. Cardiol. Apr 2016 Protein TP301604
LMO4 Cisplatin-induced Ototoxicity Is Mediated by Nitroxidative Modification of Cochlear Proteins Characterized by Nitration of Lmo4 J. Biol. Chem., May 2012; 287: 18674 - 18686. Protein TP303914
LMOD1 Nodding syndrome may be an autoimmune reaction to the parasitic worm Onchocerca volvulus Sci Transl Med 2017 Protein TP309941
LOX Blocking Surgically Induced Lysyl Oxidase Activity Reduces the Risk of Lung Metastases Cell Rep 2017 Protein TP313323
LOX Characterization of Microfibrillar-Associated Protein 4 (MFAP4) as a Tropoelastin- and Fibrillin-Binding Protein Involved in Elastic Fiber Formation J. Biol. Chem. Nov 2015 Protein TP313323
LOX The hypoxic cancer secretome induces pre-metastatic bone lesions through lysyl oxidase Nature Jun 2015 Protein TP313323
LOX Targeting the LOX/hypoxia axis reverses many of the features that make pancreatic cancer deadly: inhibition of LOX abrogates metastasis and enhances drug efficacy EMBO Mol Med Jun 2015 Protein TP313323
LOX Tissue Transglutaminase, Not Lysyl Oxidase, Dominates Early Calcium-Dependent Remodeling of Fibroblast-Populated Collagen Lattices Cells Tissues Organs (Print) Apr 2015 Protein TP313323
Lox Lysyl Oxidase Plays a Critical Role in Endothelial Cell Stimulation to Drive Tumor Angiogenesis Cancer Res., Jan 2013; 73: 583 - 594. Protein TP313323
LPLUNC1 LPLUNC1 Modulates Innate Immune Responses to Vibrio cholerae The Journal of Infectious Disease, Nov 2011; 204: 1349 - 1357. Protein TP303281
LTC4S Maresin conjugates in tissue regeneration biosynthesis enzymes in human macrophages Proc. Natl. Acad. Sci. U.S.A. 2016 Protein TP306062
LY500004 Matrix Metalloproteinase-19 Promotes Metastatic Behavior In Vitro and is Associated with Increased Mortality in Non-small Cell Lung Cancer Am. J. Respir. Crit. Care Med. Sep 2014 Protein LY500003
LY500005 Matrix Metalloproteinase-19 Promotes Metastatic Behavior In Vitro and is Associated with Increased Mortality in Non-small Cell Lung Cancer Am. J. Respir. Crit. Care Med. Sep 2014 Protein LY500004
LY500007 Matrix Metalloproteinase-19 Promotes Metastatic Behavior In Vitro and is Associated with Increased Mortality in Non-small Cell Lung Cancer Am. J. Respir. Crit. Care Med. Sep 2014 Protein LY500005
LY500009 Matrix Metalloproteinase-19 Promotes Metastatic Behavior In Vitro and is Associated with Increased Mortality in Non-small Cell Lung Cancer Am. J. Respir. Crit. Care Med. Sep 2014 Protein LY500007
LY96 Amniotic Fluid Soluble Myeloid Differentiation-2 (sMD-2) as Regulator of Intra-amniotic Inflammation in Infection-induced Preterm Birth Am. J. Reprod. Immunol. Jan 2015 Protein TP304686
Lysates Development of a coordinated allo T-cell and auto B-cell response against autosomal PTK2B after allogeneic hematopoietic stem cell transplantation Haematologica. 2013 Oct 4 Protein
Lysates Development of a coordinated allo T-cell and auto B-cell response against autosomal PTK2B after allogeneic hematopoietic stem cell transplantation Haematologica. 2013 Oct 4 Protein
Lysates Development of a coordinated allo T-cell and auto B-cell response against autosomal PTK2B after allogeneic hematopoietic stem cell transplantation Haematologica. 2013 Oct 4 Protein
MAGEA4 Case-Control Study: Smoking History Affects the Production of Tumor Antigen-Specific Antibodies NY-ESO-1 in Patients with Lung Cancer in Comparison with Cancer Disease-Free Group J Thorac Oncol 2016 Protein TP318952
MAGEA4 Expression of tumor antigens on primary ovarian cancer cells compared to established ovarian cancer cell lines Oncotarget 2016 Protein TP318952
MARCKS Identification of novel phosphatidic acid-binding proteins in the rat brain Neurosci. Lett. Apr 2015 Protein TP310277
MATR3 Mutations in the Matrin 3 gene cause familial amyotrophic lateral sclerosis Nat. Neurosci. 664-6 17 5. May 2014 Protein TP323258
MAVS Dengue virus subverts host innate immunity by targeting adaptor protein MAVS J. Virol. Jun 2016 Protein TP308175
MBNL1 Muscleblind-like 1 activates insulin receptor exon 11 inclusion by enhancing U2AF65 binding and splicing of the upstream intron J. Cell Sci., Aug 2013; 126: 3782 - 3795. Protein TP323216
MCHERRY Stoichiometries of U2AF35, U2AF65 and U2 snRNP reveal new early spliceosome assembly pathways Nucleic Acids Res. 2016 Protein TP790040
MDA5 Anti-MDA5 Antibodies in a Large Mediterranean Population of Adults with Dermatomyositis Journal of Immunology Research, Feb 2014. Protein TP315661
MDK Intratumoural heterogeneity generated by Notch signalling promotes small-cell lung cancer Nature 2017 Protein TP723299
MDM2 Regulation of Cell Proliferation and Migration by miR-203 via GAS41/miR-10b Axis in Human Glioblastoma Cells PLoS ONE 2016 Protein LY400855
MFN2 Mfn2 Couples Glutamate Excitotoxicity and Mitochondrial Dysfunction in Motor Neurons J. Biol. Chem. Nov 2014 Protein TP326143
MGEA5 Thiamet-G-mediated inhibition of O-GlcNAcase sensitizes human leukemia cells to microtubule-stabilizing agent paclitaxel Biochem. Biophys. Res. Commun. Sep 2014 Protein TP322411
MIB1 ML372 blocks SMN ubiquitination and improves spinal muscular atrophy pathology in mice JCI Insight 2016 Protein TP321377
MIB1 ML372 blocks SMN ubiquitination and improves spinal muscular atrophy pathology in mice JCI Insight 2016 Protein TP321377
MIB1 The E3 ubiquitin ligase mind bomb 1 ubiquitinates and promotes the degradation of survival of motor neuron protein Mol. Biol. Cell, Jun 2013; 24: 1863 - 1871. Protein TP321377
MIIP MIIP?haploinsufficiency induces chromosomal instability and promotes tumour progression in colorectal cancer J. Pathol. 2016 Protein TP300779
MKNK2 Proteome-wide epitope mapping of antibodies using ultra-dense peptide arrays Mol. Cell Proteomics. April 2014 Protein LY413712
MORC3 Calcinosis in juvenile dermatomyositis is influenced by both anti-NXP2 autoantibody status and age at disease onset Rheumatology (Oxford) July 2014 Protein TP310530
MOV10 Mov10 suppresses retroelements and regulates neuronal development and function in the developing brain BMC Biol. 2017 Protein TP300934
MS4A8B Proteome-wide epitope mapping of antibodies using ultra-dense peptide arrays Mol. Cell Proteomics. April 2014 Protein LY403116
MSMP Induction of anti-VEGF therapy resistance by upregulated expression of microseminoprotein (MSMP) Oncogene 2017 Protein TP322527
MSN Are ERM (ezrin/radixin/moesin) proteins targets for autoantibodies in demyelinating neuropathies? Hum. Immunol. Oct 2014 Protein TP305674
MTDH Ezrin binds to DEAD-box RNA helicase DDX3 and regulates its function and protein level Mol. Cell. Biol. Jul 2015 Protein TP307238
MTMR14 The small molecule AUTEN-99 (autophagy enhancer-99) prevents the progression of neurodegenerative symptoms Sci Rep 2017 Protein TP300809
MTMR14 AUTEN-67, an autophagy-enhancing drug candidate with potent antiaging and neuroprotective effects Autophagy Aug 2015 Protein TP300809
MTOR mTORC2 promotes type I insulin-like growth factor receptor and insulin receptor activation through the tyrosine kinase activity of mTOR Cell Res. Nov 2015 Protein TP320457
MUC1 Enhanced binding of antibodies generated during chronic HIV infection to mucus component MUC16 Mucosal Immunol 2016 Protein TP321390
MUC1 Anti-Peptide Monoclonal Antibodies Generated for Immuno-Multiple Reaction Monitoring-Mass Spectrometry Assays Have a High Probability of Supporting Western blot and ELISA Mol. Cell Proteomics Feb 2015 Protein LY422694
MYC Autoantibodies against oncogenic ERG protein in prostate cancer: potential use in diagnosis and prognosis in a panel with C-MYC, AMACR and HERV-K Gag Genes & Cancer 2016 Protein TP301611
MYC Pioneer transcription factors target partial DNA motifs on nucleosomes to initiate reprogramming Cell Apr 2015 Protein TP301611
MYC Reversible linkage of two distinct small molecule inhibitors of myc generates a dimeric inhibitor with improved potency that is active in myc over-expressing cancer cell lines PLoS ONE Apr 2015 Protein TP301611
MYC Sin3b Interacts with Myc and Decreases Myc Levels J. Biol. Chem. Jun 2014 Protein TP301611
NAA50 Chemoproteomic Profiling of Lysine Acetyltransferases Highlights an Expanded Landscape of Catalytic Acetylation J. Am. Chem. Soc. May 2014 Protein TP303388
NANS N-Acetylneuraminic Acid Synthase (NANS) Handbook of Glycosyltransferases and Related Genes, Feb 2014. Protein TP300123
NASP KBILDS: A kinase substrate discovery tool ChemBioChem 2016 Protein TP304052
NASP KBILDS: A kinase substrate discovery tool ChemBioChem 2016 Protein TP304052
NASP K-BILDS: A Kinase Substrate Discovery Tool Chembiochem 2016 Protein TP304052
NCF1 S-Glutathionylation of p47phox sustains superoxide generation in activated neutrophils Biochim. Biophys. Acta 2017 Protein TP301233
NCL The cellular protein nucleolin preferentially binds long-looped G-quadruplex nucleic acids Biochim. Biophys. Acta 2016 Protein TP319082
NCL The G-quadruplex-forming aptamer AS1411 potently inhibits HIV-1 attachment to the host cell Int. J. Antimicrob. Agents Mar 2016 Protein TP319082
NCL Nucleolin promotes in vitro translation of feline calicivirus genomic RNA Virology Dec 2015 Protein TP319082
NCL Nucleolin stabilizes G-quadruplex structures folded by the LTR promoter and silences HIV-1 viral transcription Nucleic Acids Res. Sep 2015 Protein TP319082
Negative Control CTLA-4 expression in the non-small cell lung cancer patient tumor microenvironment: diverging prognostic impact in primary tumors and lymph node metastases Cancer Immunol. Immunother. 2017 Protein LY500001
Negative Control The prognostic role of immune checkpoint markers programmed cell death protein 1 (PD-1) and programmed death ligand 1 (PD-L1) in a large, multicenter prostate cancer cohort oncotarget 2016 Protein LY500001
negative control Assessing PD-L1 and PD-1 in Non-Small Cell Lung Cancer (NSCLC): a Novel Immunoscore Approach Clinical Lung Cancer 2016 Protein LY500001
NEU1 Sialidase inhibitors attenuate pulmonary fibrosis in a mouse model Sci Rep 2017 Protein TP300386
NEU2 Sialidase inhibitors attenuate pulmonary fibrosis in a mouse model Sci Rep 2017 Protein TP319858
NEU3 Sialidase inhibitors attenuate pulmonary fibrosis in a mouse model Sci Rep 2017 Protein TP316537
NEU4 Sialidase inhibitors attenuate pulmonary fibrosis in a mouse model Sci Rep 2017 Protein TP303948
NFKBIE A Map of Human Mitochondrial Protein Interactions Linked to Neurodegeneration Reveals New Mechanisms of Redox Homeostasis and NF-κB Signaling Cell Syst 2017 Protein TP760703
NFKBIE Annexin A4 and A6 induce membrane curvature and constriction during cell membrane repair Nat Commun 2017 Protein TP760703
NIT2 The Enzymology of 2-Hydroxyglutarate, 2-Hydroxyglutaramate and 2-Hydroxysuccinamate and Their Relationship to Oncometabolites Biology (Basel) 2017 Protein TP310660
NLGN3 Neuronal Activity Promotes Glioma Growth through Neuroligin-3 Secretion Cell Apr 2015 Protein TP307955
NLN Analysis of the proteolysis of bioactive peptides using a peptidomics approach Nature Protocols 8, 1730-1742 doi:10.1038/nprot.2013.104 Protein TP312447
NLRP10 Glial Uptake of Amyloid Beta Induces NLRP3 Inflammasome Formation via Cathepsin-Dependent Degradation of NLRP10 Neuromolecular Med. Nov 2013 Protein TP311215
NPTX2 Neuronal Pentraxin 2 is a regulator of clear cell renal cell carcinoma malignancy through activation of the AMPA-selective glutamate receptor 4 Cancer Res. Jun 2014 Protein TP306713
NR1H2 Fungal-derived neoechinulin B as a novel antagonist of liver X receptor, identified by chemical genetics using hepatitis C virus cell culture system J. Virol. 2016 Protein TP308381
NR1H3 Insulin induction of SREBP-1c in rodent liver requires LXRa-C/EBPß complex Proc. Natl. Acad. Sci. U.S.A. 2016 Protein TP323767
NRGN Derivation of a Three Biomarker Panel to Improve Diagnosis in Patients with Mild Traumatic Brain Injury Front Neurol 2017 Protein TP301209
NRGN Derivation of a Three Biomarker Panel to Improve Diagnosis in Patients with Mild Traumatic Brain Injury Front Neurol 2017 Protein TP301209
NUDT1 Addiction to MTH1 protein results in intense expression in human breast cancer tissue as measured by liquid chromatography-isotope-dilution tandem mass spectrometry DNA Repair Jun 2015 Protein LY419314
NXP2 Oral Abstracts 3: Adolescent and Young Adult • O13. Hypermobility is a Risk Factor for Musculoskeletal Pain in Adolescence: Findings From a Prospective Cohort Study Rheumatology, Apr 2013; 52: i33 - i43. Protein TP310530
ODC1 A Label-Free Continuous Fluorescence-Based Assay for Monitoring Ornithine Decarboxylase Activity with a Synthetic Putrescine Receptor SLAS Discovery 2017 Protein TP306858
ODC1 Cystathionine-beta-synthase inhibition for colon cancer: Enhancement of the efficacy of aminooxyacetic acid via the prodrug approach Mol. Med. 2016 Protein TP306858
ODC1 Cystathionine-beta-synthase inhibition for colon cancer: Enhancement of the efficacy of aminooxyacetic acid via the prodrug approach Mol. Med. 2016 Protein TP306858
OLR1 The lipid moiety 7-ketocholesteryl-9-carboxynonanoate mediates binding interaction of oxLDL to LOX-1 and upregulates ABCA1 expression through PPARγ Life Sci. 2017 Protein TP304704
p65 TNF-a Induction of CXCL10 in Endothelial Cells Requires Protein Arginine Methyltransferase 5 (PRMT5)-mediated NF-?B p65 Methylation J. Biol. Chem. April 2014 Protein TA301086
PACRG Pan-Cancer Analysis Links PARK2 to BCL-XL-Dependent Control of Apoptosis. Neoplasia 2016 Protein TP322240
PCBP2 Unique C. elegans telomeric overhang structures reveal the evolutionarily conserved properties of telomeric DNA Nucleic Acids Res. Apr 2015 Protein TP310035
PDCD1 The prognostic role of immune checkpoint markers programmed cell death protein 1 (PD-1) and programmed death ligand 1 (PD-L1) in a large, multicenter prostate cancer cohort oncotarget 2016 Protein LY401555
PDCD1 Assessing PD-L1 and PD-1 in Non-Small Cell Lung Cancer (NSCLC): a Novel Immunoscore Approach Clinical Lung Cancer 2016 Protein LY401555
PDE4A Resveratrol directly targets DDX5 resulting in suppression of the mTORC1 pathway in prostate cancer Cell Death Dis May 2016 Protein TP307765
PDGFD Neuropilin 1 binds platelet-derived growth factor (PDGF)-D and is a co-receptor in PDGF-D/PDGF receptor β signaling J. Cell. Sci 2017 Protein TP760442
PF4 Critical role of CXCL4 in the lung pathogenesis of influenza (H1N1) respiratory infection Mucosal Immunol 2017 Protein TP311322
PFKP PPARγ Links BMP2 and TGFβ1 Pathways in Vascular Smooth Muscle Cells, Regulating Cell Proliferation and Glucose Metabolism Cell Metab. 2017 Protein TP300673
PFN1 Phosphoglycerate mutase 1 promotes cancer cell migration independent of its metabolic activity Oncogene 2016 Protein TP302338
PGLYRP2 A Novel Innate Response of Human Corneal Epithelium to Heat-killed Candida albicans by Producing Peptidoglycan Recognition Proteins PLoS ONE Jun 2015 Protein TP315773
PHLPP1 Role of PHLPP1 in inflammation response: Its loss contributes to gliomas development and progression Int. Immunopharmacol. Mar 2016 Protein TP303930
PHLPP1 An ATP-Site On-Off Switch That Restricts Phosphatase Accessibility of Akt Sci. Signal., May 2012; 5: ra37. Protein TP303930
PICALM Central role for PICALM in amyloid-[beta] blood-brain barrier transcytosis and clearance Nature Neuroscience May 2015 Protein TP313791
PICALM Central role for PICALM in amyloid-ß blood-brain barrier transcytosis and clearance Nat. Neurosci. May 2015 Protein TP313791
PIK3CG Cilostazol Induces PGI2 Production via Activation of the Downstream Epac-1/Rap1 Signaling Cascade to Increase Intracellular Calcium by PLCe and to Activate p44/42 MAPK in Human Aortic Endothelial Cells PLoS ONE Jul 2015 Protein TP307790
PIP Role of dendritic cell maturation factors produced by human invariant NKT cells in immune tolerance J. Leukoc. Biol. 2016 Protein TP303135
PIP Role of dendritic cell maturation factors produced by human invariant NKT cells in immune tolerance J. Leukoc. Biol. 2016 Protein TP303135
PLAUR Ligand binding alters dimerization and sequestering of urokinase receptors in raft-mimicking lipid mixtures Biophys. J. Nov 2014 Protein TP301222
PLK1 HIV-1 blocks the signaling adaptor MAVS to evade antiviral host defense after sensing of abortive HIV-1 RNA by the host helicase DDX3 Nat. Immunol 2016 Protein TP301795
PNP Evidence for purine nucleoside phosphorylase (PNP) release from RAT C6 glioma cells J. Neurochem 2017 Protein TP310759
PODN Podocan is expressed in blood and adipose tissue and correlates negatively with the induction of diabetic nephropathy Journal of Medicinal Chemistry 2017 Protein TP305567
PODXL Membranous expression of podocalyxin-like protein is an independent factor of poor prognosis in urothelial bladder cancer British Journal of Cancer doi:10.1038/bjc.2013.215 Protein LY401657
POT1 An H2A Histone Isotype, H2ac, Associates with Telomere and Maintains Telomere Integrity PLoS ONE May 2016 Protein TP316275
POT1 The OB-fold domain 1 of human POT1 recognizes both telomeric and non-telomeric DNA motifs Biochimie Apr 2015 Protein TP316275
POU5F1 Pioneer transcription factors target partial DNA motifs on nucleosomes to initiate reprogramming Cell Apr 2015 Protein TP311998
PPM1G WIP1 Phosphatase as a Potential Therapeutic Target in Neuroblastoma PLoS ONE Feb 2015 Protein TP313685
PPM1H WIP1 Phosphatase as a Potential Therapeutic Target in Neuroblastoma PLoS ONE Feb 2015 Protein TP317548
PPP1CB Inhibitory Member of the Apoptosis-stimulating Proteins of the p53 Family (iASPP) Interacts with Protein Phosphatase 1 via a Noncanonical Binding Motif J. Biol. Chem., Dec 2011; 286: 43039 - 43044. Protein TP301142
PRMT1 Dynamic arginine methylation of TNF receptor associated factor 6 regulates Toll-like receptor signaling J. Biol. Chem. Jul 2015 Protein TP324239
PROM1 Functional links between gelatinase B/matrix metalloproteinase-9 and prominin-1/CD133 in diabetic retinal vasculopathy and neuropathy Prog Retin Eye Res July 2014 Protein TP321611
PROP1 Involvement of PIT-1-reactive cytotoxic T lymphocytes in anti-PIT-1 antibody syndrome J. Clin. Endocrinol. Metab. Jun 2014 Protein TP318746
PROP1 Involvement of PIT-1-Reactive Cytotoxic TLymphocytes in Anti-PIT-1 Antibody Syndrome J Clin Endocrinol Metab Jun 2014 Protein TP318746
PROS1 An engineered Axl 'decoy receptor' effectively silences the Gas6-Axl signaling axis Nat. Chem. Biol. Sep 2014 Protein TP302073
Protein Inactivation of Chibby affects function of motile airway cilia J. Cell Biol., Apr 2009; 185: 225 - 233. Protein
PRSS1 Antigen-specificity of antiretinal antibodies in patients with noninfectious uveitis Canadian Journal of Ophthalmology / Journal Canadien d'Ophtalmologie 2017 Protein TP721067
PRY2 Proteome-wide epitope mapping of antibodies using ultra-dense peptide arrays Mol. Cell Proteomics. April 2014 Protein LY424151
PS100001 Restored immunosuppressive effect of mesenchymal stem cells on B cells after OAZ downregulation in patients with systemic lupus erythematosus Arthritis & rheumatology Sep 2014 Protein TF81001
PS100001 Matrix Metalloproteinase-19 Promotes Metastatic Behavior In Vitro and is Associated with Increased Mortality in Non-small Cell Lung Cancer Am. J. Respir. Crit. Care Med. Sep 2014 Protein LY500009
PS100010 The Use of a Stably Expressed FRET Biosensor for Determining the Potency of Cancer Drugs PLoS ONE Sep 2014 Protein
PSG1 Cystathionine ß-synthase regulates endothelial function via protein S-sulfhydration FASEB J. Sep 2015 Protein TP304978
PTEN ATM-mediated PTEN phosphorylation promotes PTEN nuclear translocation and autophagy in response to DNA-damaging agents in cancer cells Autophagy Feb 2015 Protein TP710023
PTGIS Calpain 1 cleaves and inactivates prostacyclin synthase in mesenteric arteries from diabetic mice Basic Res. Cardiol 2017 Protein TP311030
PTGR1 Mapping Novel Metabolic Nodes Targeted by Anti-Cancer Drugs that Impair Triple-Negative Breast Cancer Pathogenicity ACS Chem. Biol 2017 Protein TP306692
PTK2 Intracellular HMGB1 Negatively Regulates Efferocytosis J. Immunol., Nov 2011; 187: 4686 - 4694. Protein TP319839
PUF60 PUF60: a prominent new target of the autoimmune response in dermatomyositis and Sjögren's syndrome Ann. Rheum. Dis. Aug 2015 Protein TP323492
PUMA HER2 Phosphorylates and Destabilizes Pro-Apoptotic PUMA, Leading to Antagonized Apoptosis in Cancer Cells PLoS ONE e78836 Nov 2013 Protein TP325345
PVRIG Translational plasticity facilitates the accumulation of nonsense genetic variants in the human population Genome Res. 2016 Protein LY411386
PXN Autophagy Promotes Focal Adhesion Disassembly and Cell Motility of Metastatic Tumor Cells through the Direct Interaction of Paxillin with LC3 Cell Rep May 2016 Protein TP313811
PXN Paxillin and focal adhesion kinase colocalise in human skeletal muscle and its associated microvasculature Histochem. Cell Biol. Mar 2014 Protein TP313811
PXR protein Cyclin-dependent kinase 2 negatively regulates human pregnane X receptor-mediated CYP3A4 gene expression in HepG2 liver carcinoma cells J. Biol. Chem., Sep 2008; 10.1074/jbc.M806132200. Protein TP305691
RAB5C Epigenetic activation of a cryptic TBC1D16 transcript enhances melanoma progression by targeting EGFR Nat. Med. Jun 2015 Protein TP310698
RAB7A Early to Intermediate Steps of Tumor Embolic Formation Involve Specific Proteolytic Processing of E-Cadherin Regulated by Rab7 Mol. Cancer Res., Jun 2012; 10: 713 - 726. Protein TP301776
RAD18 USP7 is essential for maintaining Rad18 stability and DNA damage tolerance Oncogene May 2015 Protein TP301700
RAG1 Physiological significance of Rag1 in neuronal death, especially optic neuropathy FEBS J. Oct 2014 Protein LY424712
RBCK1 The paracaspase MALT1 cleaves HOIL1 reducing linear ubiquitination by LUBAC to dampen lymphocyte NF-?B signalling Nat Commun Nov 2015 Protein TP303906
RBP1 Importance of ALDH1A enzymes in determining human testicular retinoic acid concentrations J. Lipid Res. Dec 2014 Protein TP314515
RBPMS The RNA binding protein RBPMS is a selective marker of ganglion cells in the mammalian retina J. Comp. Neurol. Dec 2013. Protein LY425258
RC219918 The Coordination of Netrin Signal Transduction via TUBB3 and JNK1 in Axon Thesis Jul 2013 Protein TP300755
RDH11 Sample matrix has a major impact on accuracy of peptide quantification: Assessment of calibrator and internal standard selection and method validation Analytical chemistry Dec 2015 Protein TP305003
RDH11 Sample matrix has a major impact on accuracy of peptide quantification: Assessment of calibrator and internal standard selection and method validation Analytical chemistry Dec 2015 Protein PH305003
RDX Are ERM (ezrin/radixin/moesin) proteins targets for autoantibodies in demyelinating neuropathies? Hum. Immunol. Oct 2014 Protein TP307953
RELA The M. tuberculosis HAD phosphatase (Rv3042c) interacts with host proteins and is inhibited by Clofazimine Cellular and Molecular Life Sciences Mar 2016 Protein TP320780
RELA FOXO3-NF-?B RelA Protein Complexes Reduce Proinflammatory Cell Signaling and Function J. Immunol. Nov 2015 Protein TP320780
RELA MYB Elongation Is Regulated by the Nucleic Acid Binding of NF?B p50 to the Intronic Stem-Loop Region PLoS ONE Apr 2015 Protein TP320780
RELA Functional characterization of a competitive peptide antagonist of p65 in human macrophage-like cells suggests therapeutic potential for chronic inflammation Drug Design, Development and Therapy Dec 2014 Protein TP320780
RELA Novel p65 Binding Glucocorticoid-induced Leucine Zipper Peptide Suppresses Experimental Autoimmune Encephalomyelitis J. Biol. Chem., Dec 2011; 286: 44799 - 44810. Protein TP320780
RETN Interaction between Esophageal Squamous Cell Carcinoma and Adipose Tissue in Vitro Am. J. Pathol. Mar 2016 Protein TP310942
RFTN2 Raftlin: a New Biomarker in Human Sepsis Inflammation Dec 2013. Protein TP310724
RIG-I Quantitation of the Dynamic Profiles of the Innate Immune Response Using Multiplex Selected Reaction Monitoring–Mass Spectrometry Mol. Cell. Proteomics, Jun 2013; 12: 1513 - 1529. Protein TP317615
RND3 Rnd3 as a Novel Target to Ameliorate Microvascular Leakage J Am Heart Assoc Apr 2016 Protein TP304479
RNF2 TRIM37 is a new histone H2A ubiquitin ligase and breast cancer oncoprotein Nature Nov 2014 Protein TP303089
RNF214 Proteome-wide epitope mapping of antibodies using ultra-dense peptide arrays Mol. Cell Proteomics. April 2014 Protein LY403969
RNH1 Migration towards SDF-1 selects angiogenin-expressing bone marrow monocytes endowed with cardiac reparative activity in patients with previous myocardial infarction Stem Cell Res Ther Apr 2015 Protein TP308360
ROR1 Spontaneous Immunity Against the Receptor Tyrosine Kinase ROR1 in Patients with Chronic Lymphocytic Leukemia PLoS ONE Nov 2015 Protein TP314967
RPE65 Antigen-specificity of antiretinal antibodies in patients with noninfectious uveitis Canadian Journal of Ophthalmology / Journal Canadien d'Ophtalmologie 2017 Protein TP310433
RPS6KB1 The DPYSL2 gene connects mTOR and schizophrenia Transl Psychiatry 2016 Protein TP317324
RRM2 Anti-Peptide Monoclonal Antibodies Generated for Immuno-Multiple Reaction Monitoring-Mass Spectrometry Assays Have a High Probability of Supporting Western blot and ELISA Mol. Cell Proteomics Feb 2015 Protein LY431390
RUNX1 Hyperglycemia and redox status regulate RUNX2 DNA-binding and an angiogenic phenotype in endothelial cells Microvasc. Res. Oct 2014 Protein TP323854
S100A9 CD16 is indispensable for antibody-dependent cellular cytotoxicity by human monocytes Sci Rep 2016 Protein TP308250
SAE1 Clinical characteristics of anti-SAE antibodies in Chinese patients with dermatomyositis in comparison with different patient cohorts Sci Rep 2017 Protein TP301820
SAG Antigen-specificity of antiretinal antibodies in patients with noninfectious uveitis Canadian Journal of Ophthalmology / Journal Canadien d'Ophtalmologie 2017 Protein TP320057
SAMHD1 The expression profile of sterile alpha motif and histidine-aspartate domain-containing protein 1 (SAMHD1) in feline tissues Veterinary Immunology and Immunopathology 2017 Protein LY414526
SATB1 SATB1 is an independent prognostic factor in radically resected upper gastrointestinal tract adenocarcinoma Virchows Arch. Oct 2014 Protein LY427355
SATB2 SATB1 is an independent prognostic factor in radically resected upper gastrointestinal tract adenocarcinoma Virchows Arch. Oct 2014 Protein LY414656
SCG2 REST Regulates Non-Cell-Autonomous Neuronal Differentiation and Maturation of Neural Progenitor Cells via Secretogranin II J. Neurosci. Nov 2015 Protein TP305382
serpina1 Endothelial-Mesenchymal Transition in Vascular Calcification of Ins2Akita/+ Mice PLoS ONE 2016 Protein TP302082
SERPINA1 Serine Protease Activation Essential for Endothelial-Mesenchymal Transition in Vascular Calcification Circ. Res. Aug 2015 Protein TP302082
SERPINA6 Anti-Peptide Monoclonal Antibodies Generated for Immuno-Multiple Reaction Monitoring-Mass Spectrometry Assays Have a High Probability of Supporting Western blot and ELISA Mol. Cell Proteomics Feb 2015 Protein LY419763
SERPINB1 Plasma serpinB1 is related to insulin sensitivity but not pancreatic β-Cell function in non-diabetic adults Physiol Rep 2017 Protein TP302138
SERPINB1 SerpinB1 Promotes Pancreatic ß Cell Proliferation Cell Metab. Dec 2015 Protein TP302138
SETDB1 Polycomb Repressive Complex 2 Methylates Elongin A to Regulate Transcription Mol. Cell 2017 Protein TP326620
SIRT7 Regulation of Serine-Threonine Kinase Akt Activation by NAD(+)-Dependent Deacetylase SIRT7 Cell Rep 2017 Protein TP305658
SKP2 Inhibiting the role of Skp2 suppresses cell proliferation and tumorigenesis of human gastric cancer cells via the upregulation of p27kip1 Mol Med Rep 2016 Protein TP314001
SLC14A1 Expression and localization of a UT-B urea transporter in the human bladder Am. J. Physiol. Renal Physiol. Sep 2014 Protein TP308509
SLC14A1 Expression and localization of a UT-B urea transporter in the human bladder Am. J. Physiol. Renal Physiol. Sep 2014 Protein LY402465
SLC14A1 Expression and localization of a UT-B urea transporter in the human bladder Am. J. Physiol. Renal Physiol. Sep 2014 Protein LY426961
SLC25A5 The pleiotropic regulation of cyclin D1 by newly identified sesaminol-binding protein ANT2 Oncogenesis 2017 Protein TP308949
SLC6A4 Low-level repeated exposure to diazinon and chlorpyrifos decrease anxiety-like behaviour in adult male rats as assessed by marble burying behaviour Neurotoxicology Aug 2015 Protein TP310187
SLC9A3R1 Expression of Na+/H+ exchanger regulatory factor 1 in autosomal-dominant polycystic kidney disease J. Int. Med. Res. Jul 2015 Protein TP301653
SMAD2 M10, a caspase cleavage product of the hepatocyte growth factor receptor, interacts with Smad2 and demonstrates antifibrotic properties in vitro and in vivo Transl Res Dec 2015 Protein TP304604
SMAD4 M10, a caspase cleavage product of the hepatocyte growth factor receptor, interacts with Smad2 and demonstrates antifibrotic properties in vitro and in vivo Transl Res Dec 2015 Protein TP301828
SMN ALS-associated mutations in FUS disrupt the axonal distribution and function of SMN Hum. Mol. Genet., May 2013; 10.1093/hmg/ddt222. Protein TP321367
SNAP25 SNAP-25 is a promising novel cerebrospinal fluid biomarker for synapse degeneration in Alzheimer's disease Mol Neurodegener Nov 2014 Protein TP302068
SNAP25 Targeting synaptic pathology with a novel affinity mass spectrometry approach Mol. Cell Proteomics Jun 2014 Protein TP302068
SOCS1 IFN-λ4 Attenuates Antiviral Responses by Enhancing Negative Regulation of IFN Signaling J. Immunol. 2017 Protein LY401230
SOX2 Pioneer transcription factors target partial DNA motifs on nucleosomes to initiate reprogramming Cell Apr 2015 Protein TP300757
SOX4 SOXC Transcription Factors Induce Cartilage Growth Plate Formation in Mouse Embryos by Promoting Noncanonical WNT Signaling J. Bone Miner. Res. Mar 2015 Protein TP309139
SOX9 Context-specific role of SOX9 in NF-Y mediated gene regulation in colorectal cancer cells Nucleic Acids Res. Jun 2015 Protein TP308944
SPOP Quantification of mutant SPOP proteins in prostate cancer using mass spectrometry-based targeted proteomics J Transl Med 2017 Protein TP301551
SRP54 Anti-signal recognition particle autoantibody ELISA validation and clinical associations Rheumatology (Oxford) Dec 2014 Protein TP301658
SSAT1 MicroRNAs interfere with DNA methylation in rheumatoid arthritis synovial fibroblasts Rheumatic & Musculoskeletal Diseases 2016 Protein LY401040
STARD13 Proteome-wide epitope mapping of antibodies using ultra-dense peptide arrays Mol. Cell Proteomics. April 2014 Protein LY406044
STAT1a PARP9 and PARP14 cross-regulate macrophage activation via STAT1 ADP-ribosylation Nat Commun 2016 Protein TP313858
STIM1 STIM1 activates CRAC channels through rotation of the pore helix to open a hydrophobic gate Nat Commun 2017 Protein TP305678
STK38 NDR1 protein kinase promotes IL-17- and TNF-α-mediated inflammation by competitively binding TRAF3 EMBO Rep 2017 Protein TP304133
STK38 Stk38 protein kinase preferentially inhibits TLR9-activated inflammatory responses by promoting MEKK2 ubiquitination in macrophages Nat Commun May 2015 Protein TP304133
STK38L Amplification of F-Actin Disassembly and Cellular Repulsion by Growth Factor Signaling Dev. Cell 2017 Protein TP306074
SYNJ1 Human R1441C LRRK2 regulates the synaptic vesicle proteome and phosphoproteome in a Drosophila model of Parkinson's disease Hum. Mol. Genet. 2016 Protein TP315278
SYT1 The pre-synaptic vesicle protein synaptotagmin is a novel biomarker for Alzheimer's disease Alzheimers Res Ther 2016 Protein TP327252
SYT1 The pre-synaptic vesicle protein synaptotagmin is a novel biomarker for Alzheimer's disease Alzheimers Res Ther 2016 Protein TP327252
TAGLN2 Comparative Tissue Proteomics of Microdissected Specimens Reveals Novel Candidate Biomarkers of Bladder Cancer Mol. Cell Proteomics Jun 2015 Protein TP303473
TARBP2 DICER-ARGONAUTE2 Complex in Continuous Fluorogenic Assays of RNA Interference Enzymes PLoS ONE Mar 2015 Protein PH301043
TARDBP A Liver-Enriched Long Non-Coding RNA, lncLSTR, Regulates Systemic Lipid Metabolism in Mice Cell Metab. Mar 2015 Protein TP310639
TARDBP Full-length TDP-43 forms toxic amyloid oligomers that are present in frontotemporal lobar dementia-TDP patients Nat Commun Sep 2014 Protein TP310639
TARDBP Dual vulnerability of TDP-43 to calpain and caspase-3 proteolysis after neurotoxic conditions and traumatic brain injury J. Cereb. Blood Flow Metab. Jun 2014 Protein TP310639
TFAP2A A Functional Variant Associated with Atrial Fibrillation Regulates PITX2c Expression through TFAP2a Am. J. Hum. Genet. 2016 Protein TP304603
TFAP2a A Functional Variant Associated with Atrial Fibrillation Regulates PITX2c Expression through TFAP2a AJHG 2016 Protein TP304603
TFAP2a A Functional Variant Associated with Atrial Fibrillation Regulates PITX2c Expression through TFAP2a AJHG 2016 Protein TP304603
TFEB A novel curcumin analog binds to and activates TFEB in vitro and in vivo independent of MTOR inhibition Autophagy May 2016 Protein TP760282
TGFB1 Oxidative stress is responsible for maternal diabetes-impaired transforming growth factor beta signaling in the developing mouse heart Am. J. Obstet. Gynecol. Jan 2015 Protein TP300973
TMEM5 The functional O-mannose glycan on a-dystroglycan contains a phospho-ribitol primed for matriglycan addition Elife Apr 2016 Protein TP303762
TMEM98 The Secreted Form of Transmembrane Protein 98 Promotes the Differentiation of T Helper 1 Cells J. Interferon Cytokine Res. May 2015 Protein TP301829
TNF IL21R expressing CD14+CD16+ monocytes expand in multiple myeloma patients leading to increased osteoclasts Haematologica 2017 Protein TP306983
TNF Melanocyte pigmentation inversely correlates with MCP-1 production and angiogenesis-inducing potential FASEB J. Nov 2014 Protein TP306983
TNFRSF10B/DR5 Hepatitis B virus-triggered autophagy targets TNFRSF10B/death receptor 5 for degradation to limit TNFSF10/TRAIL response Autophagy 2016 Protein TP319808
TP53 A Novel In Vitro CypD-Mediated p53 Aggregation Assay Suggests a Model for Mitochondrial Permeability Transition by Chaperone Systems J. Mol. Biol. 2016 Protein TP300003
TP53 Species-specific mutual regulation of p53 and miR-138 between human, rat and mouse Sci Rep May 2016 Protein TP300003
TP63 An Immunohistochemical Analysis of a Newly Developed, Mouse Monoclonal p40 (BC28) in Lung, Bladder, Skin, Breast, Prostate, and Head and Neck Cancers Arch. Pathol. Lab. Med., Feb 2014. Protein LY418475
TPK1 The JAK2 Inhibitor Fedratinib Inhibits Thiamine Uptake - A Putative Mechanism for the Onset of Wernicke's Encephalopathy Drug Metab. Dispos. July 2014 Protein TP309721
TRAF6 Ubiquitin-specific Protease 20 Regulates the Reciprocal Functions of β-Arrestin2 in Toll-like Receptor 4-promoted Nuclear Factor κB (NFκB) Activation Journal of Biological Chemistry 2016 Protein TP319528
TRAF6 Dynamic arginine methylation of TNF receptor associated factor 6 regulates Toll-like receptor signaling J. Biol. Chem. Jul 2015 Protein TP319528
TRH Vulnerability of Purkinje Cells Generated from Spinocerebellar Ataxia Type 6 Patient-Derived iPSCs Cell Rep 2016 Protein TP319231
TRIM33 Anti-TIF1 antibodies (anti-p155) in adult patients with dermatomyositis: comparison of different diagnostic assays Ann Rheum Dis, Jan 2012; 10.1136/annrheumdis-2011-200871. Protein TP312497
TRPV3 TRPV3 expression and vasodilator function in isolated uterine radial arteries from non-pregnant and pregnant rats Vascul. Pharmacol. Apr 2016 Protein LY403422
TSPO Discovery of thienopyrrolotriazine derivatives to protect mitochondrial function against Aβ-induced neurotoxicity Eur J Med Chem 2017 Protein TP320107
TSPO Discovery of benzimidazole derivatives as modulators of mitochondrial function: A potential treatment for Alzheimer's disease Eur J Med Chem 2016 Protein TP320107
TSPO Discovery of benzimidazole derivatives as modulators of mitochondrial function: A potential treatment for Alzheimer's disease Eur J Med Chem 2016 Protein TP320107
TUBB Screening Citrullinated Proteins in Synovial Tissues of Rheumatoid Arthritis Using 2-dimensional Western Blotting J Rheumatol, Mar 2013; 40: 219 - 227. Protein TP303629
TUBB3 Coordinated interaction of Down syndrome cell adhesion molecule and deleted in colorectal cancer with dynamic TUBB3 mediates Netrin-1-induced axon branching Neuroscience May 2015 Protein TP300755
TUBB3 Direct binding of TUBB3 with DCC couples netrin-1 signaling to intracellular microtubule dynamics in axon outgrowth and guidance J. Cell Sci., Jul 2013; 126: 3070 - 3081. Protein TP300755
UBE2L3 The Level of Autoantibodies Targeting Eukaryote Translation Elongation Factor 1 a1 and Ubiquitin-Conjugating Enzyme 2L3 in Nondiabetic Young Adults Diabetes Metab J Nov2015 Protein TP308780
UBE2L3 Identification of Novel Autoantibodies in Type 1 Diabetic Patients Using a High-Density Protein Microarray Diabetes Jun 2014 Protein TP308780
UGT2B15 Human Hepatic UGT2B15 Developmental Expression Toxicol. Sci. Jun 2014 Protein TP315344
UMPS Metabolomics Identifies Pyrimidine Starvation as the Mechanism of 5-Aminoimidazole-4-Carboxamide-1-ß-Riboside-Induced Apoptosis in Multiple Myeloma Cells Mol. Cancer Ther., Jul 2013; 12: 1310 - 1321. Protein TP301324
USP20 Ubiquitin-specific Protease 20 Regulates the Reciprocal Functions of β-Arrestin2 in Toll-like Receptor 4-promoted Nuclear Factor κB (NFκB) Activation Journal of Biological Chemistry 2016 Protein TP308051
USP24 EGF-mediated inhibition of ubiquitin-specific peptidase 24 expression has a crucial role in tumorigenesis Oncogene 2016 Protein TP329472
VASH2 Vasohibin 2 promotes human luminal breast cancer angiogenesis in a non-paracrine manner via transcriptional activation of fibroblast growth factor 2 Cancer Lett. 2016 Protein TP308692
VAV1 Phospholipase D2 (PLD2) is a guanine nucleotide exchange factor (GEF) for the GTPase Rac2 PNAS, Dec 2011; 108: 19617 - 19622. Protein TP324806
VAV2 Tyr42 phosphorylation of RhoA GTPase promotes tumorigenesis through nuclear factor (NF)-κB Free Radic. Biol. Med. 2017 Protein TP316175
VCL Autoantibodies against vinculin in patients with chronic inflammatory demyelinating polyneuropathy Journal of Neuroimmunology Oct 2015 Protein TP304576
VHL Protein 4.1 R Influences Myogenin Protein Stability and Skeletal Muscle Differentiation Journal of Biological Chemistry 2016 Protein TP316151
VHL Protein 4.1 R Influences Myogenin Protein Stability and Skeletal Muscle Differentiation Journal of Biological Chemistry 2016 Protein TP316151
VSNL1 A novel method for the rapid detection of post-translationally modified visinin-like protein 1 in rat models of brain injury Brain Inj 2017 Protein TP305337
WNT10A Roles of Heparan Sulfate Sulfation in Dentinogenesis J. Biol. Chem., Apr 2012; 287: 12217 - 12229. Protein LY403062
XPNPEP1 Anti-Peptide Monoclonal Antibodies Generated for Immuno-Multiple Reaction Monitoring-Mass Spectrometry Assays Have a High Probability of Supporting Western blot and ELISA Mol. Cell Proteomics Feb 2015 Protein LY402779
XRCC4 Quantification of XRCC and DNA-PK proteins in cancer cell lines and human tumors by LC-MS/MS Bioanalysis May 2014 Protein TP318029
XRCC4 Quantification of XRCC and DNA-PK proteins in cancer cell lines and human tumors by LC-MS/MS Bioanalysis May 2014 Protein PH318029
XRN2 Hepatitis C Virus Subverts Liver-Specific miR-122 to Protect the Viral Genome from Exoribonuclease Xrn2 Cell Host Microbe Aug 2014 Protein TP323980
YBX1 Autism-specific maternal autoantibodies recognize critical proteins in developing brain Translational Psychiatry 3, e277 doi:10.1038/tp.2013.50 Protein LY417905
YWHAE Epilepsy-associated gene Nedd4-2 mediates neuronal activity and seizure susceptibility through AMPA receptors PLoS Genet 2017 Protein TP300245
ZNF148 Functional characterization of a multi-cancer risk locus on chr5p15.33 reveals regulation of TERT by ZNF148 Nat Commun 2017 Protein TP602963
ZNF750 ZNF750 interacts with KLF4 and RCOR1, KDM1A, and CTBP1/2 chromatin regulators to repress epidermal progenitor genes and induce differentiation genes Genes Dev. Sep 2014 Protein TP760460