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GFAP | Scientific Research in GFAP Gene and Alexander Disease
GFAP is one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in the GFAP gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system.
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Image reference: www.sites.lafayette.edu/neur401-sp10/methodology/immunohistological-markers
GFAP UltraMab™ Antibody
| SKU# | UM500094 |
|---|---|
| Target | Homo sapiens glial fibrillary acidic protein (GFAP), transcript variant 1 |
| Host | Mouse |
| Reactivity | Human, Rat |
| Tested Application | WB, IHC, IF |
| Dilution | WB: 1:2000, IHC: 1:100, IF: 1:100 |
Confocal immunofluorescence image of primary rat neurons labeled with GFAP mouse monoclonal antibody (green) (SKU# UM500094) and DAPI (blue) for nuclear. Scale car, 20 µm
IHC staining of FFPE human embryonic cerebellum using GFAP mouse monoclonal antibody (SKU# UM500094). For FFPE tissues, HIER pretreatment with citrate pH 6.0 is required. Detection was done with Polink2 HRP for DAB.
Common Targets In Neuroscience
| Targets | Product Description | SKU |
|---|---|---|
| UCH-L1 (PGP9.5) | Mouse Monoclonal Antibody | UM800136 |
| Purifed Recombinant Protein | TP301803 | |
| Over-expression Lysate | LY401345 | |
| Tagged Lentiviral ORF Clone | RC201803L3 | |
| Gene Knockout Kit (CRISPR) | KN401803 | |
| GFAP | Mouse Monoclonal Antibody | UM500094 |
| Purifed Recombinant Protein | TP304548 | |
| Over-expression Lysate | LY419563 | |
| Tagged Lentiviral ORF Clone | RC204548L3 | |
| Gene Knockout Kit (CRISPR) | KN404548 | |
| N-Cadherin (CCH2) | Mouse Monoclonal Antibody | UM500023 |
| Purified Recombinant Protein | TP307170 | |
| Over-expression Lysate | LY419743 | |
| Tagged Lentiviral ORF Clone | RC207170L3 | |
| Gene Knockout Kit (CRISPR) | KN407170 | |
| IDH1 | Mouse Monoclonal Antibody | TA500610 |
| Purified Recombinant Protein | TP310582 | |
| Over-expression Lysate | LY401782 | |
| Tagged Lentiviral ORF Clone | RC210582L3 | |
| Gene Knockout Kit (CRISPR) | KN410582 | |
| Vimentin (VIM) | Mouse Monoclonal Antibody | UM800055 |
| Purified Recombinant Protein | TP301546 | |
| Over-expression Lysate | LY401165 | |
| Tagged Lentiviral ORF Clone | RC201546L3 | |
| Gene Knockout Kit (CRISPR) | KN401546 | |
| SOX2 | Rabbit Monoclonal Antibody | TA591006 |
| Purified Recombinant Protein | TP300757 | |
| Over-expression Lysate | LY401083 | |
| Tagged Lentiviral ORF Clone | RC200757L3 | |
| Gene Knockout Kit (CRISPR) | KN400757 | |
| Tau (MAPT) | Mouse Monoclonal Antibody | UM800131 |
| Purified Recombinant Protein | TP313312 | |
| Over-expression Lysate | LY401790 | |
| Tagged Lentiviral ORF Clone | RC213312L3 | |
| Gene Knockout Kit (CRISPR) | KN413312 |