GFAP | Scientific Research in GFAP Gene and Alexander Disease
GFAP is one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in the GFAP gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system.

Image reference: www.sites.lafayette.edu/neur401-sp10/methodology/immunohistological-markers
GFAP UltraMab™ Antibody
| SKU# | |
|---|---|
| Target | Homo sapiens glial fibrillary acidic protein (GFAP), transcript variant 1 |
| Host | Mouse |
| Reactivity | Human, Rat |
| Tested Application | WB, IHC, IF |
| Dilution | WB: 1:2000, IHC: 1:100, IF: 1:100 |

Confocal immunofluorescence image of primary rat neurons labeled with GFAP mouse monoclonal antibody (green) (SKU# UM500094) and DAPI (blue) for nuclear. Scale car, 20 µm

IHC staining of FFPE human embryonic cerebellum using GFAP mouse monoclonal antibody (SKU# UM500094). For FFPE tissues, HIER pretreatment with citrate pH 6.0 is required. Detection was done with Polink2 HRP for DAB.
Common Targets In Neuroscience
| Targets | Product Description | SKU |
|---|---|---|
| UCH-L1 (PGP9.5) | Mouse Monoclonal Antibody | |
| Purifed Recombinant Protein | ||
| Over-expression Lysate | ||
| Tagged Lentiviral ORF Clone | ||
| Gene Knockout Kit (CRISPR) | ||
| GFAP | Mouse Monoclonal Antibody | |
| Purifed Recombinant Protein | ||
| Over-expression Lysate | ||
| Tagged Lentiviral ORF Clone | ||
| Gene Knockout Kit (CRISPR) | ||
| N-Cadherin (CCH2) | Mouse Monoclonal Antibody | |
| Purified Recombinant Protein | ||
| Over-expression Lysate | ||
| Tagged Lentiviral ORF Clone | ||
| Gene Knockout Kit (CRISPR) | ||
| IDH1 | Mouse Monoclonal Antibody | |
| Purified Recombinant Protein | ||
| Over-expression Lysate | ||
| Tagged Lentiviral ORF Clone | ||
| Gene Knockout Kit (CRISPR) | ||
| Vimentin (VIM) | Mouse Monoclonal Antibody | |
| Purified Recombinant Protein | ||
| Over-expression Lysate | ||
| Tagged Lentiviral ORF Clone | ||
| Gene Knockout Kit (CRISPR) | ||
| SOX2 | Rabbit Monoclonal Antibody | |
| Purified Recombinant Protein | ||
| Over-expression Lysate | ||
| Tagged Lentiviral ORF Clone | ||
| Gene Knockout Kit (CRISPR) | ||
| Tau (MAPT) | Mouse Monoclonal Antibody | |
| Purified Recombinant Protein | ||
| Over-expression Lysate | ||
| Tagged Lentiviral ORF Clone | ||
| Gene Knockout Kit (CRISPR) |