STING(TMEM173) (NM_198282) Human Recombinant Protein

CAT#: TP308418

Recombinant protein of human transmembrane protein 173 (TMEM173)

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 Product Datasheet for 'TP308418'

USD 680.00


Availability*
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Size
    • 20 ug

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Specifications

Product Data
Description Recombinant protein of human transmembrane protein 173 (TMEM173)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence Recombinant protein was produced with TrueORF clone, RC208418. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag C-MYC/DDK
Predicted MW 42 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Reference Data
RefSeq NP_938023
Locus ID 340061
Refseq Size 1714
Cytogenetics 5q31.2
Refseq ORF 1137
Synonyms ERIS; hMITA; hSTING; MITA; MPYS; NET23; SAVI; STING
Summary This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014].
Protein Pathways
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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