TRIM21 (NM_003141) Human Recombinant Protein
$867.00
In Stock*
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 54 kDa |
| Concentration | >0.1 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_003132 |
| Locus ID | 6737 |
| UniProt ID | P19474 |
| Cytogenetics | 11p15.4 |
| RefSeq Size | 1946 |
| RefSeq ORF | 1425 |
| Synonyms | RNF81; Ro/SSA; RO52; SSA; SSA1 |
| Summary | This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined. provided by RefSeq, Jul 2008 |
| Protein Categories | Intracellular Proteins |
| Protein Families | Druggable Genome |
| Protein Pathways | Systemic lupus erythematosus |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "TRIM21" proteins (3)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH302088 | TRIM21 MS Standard C13 and N15-labeled recombinant protein (NP_003132) | 10 ug |
$3,360.00
|
|
| LC401090 | Lyophilized TRIM21 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY401090 | Transient overexpression lysate of tripartite motif-containing 21 (TRIM21) (as WB positive control) | 100 ug |
$436.00
|
|
Citations
TRIM21, a negative modulator of LFG in breast carcinoma MDA-MB-231 cells in vitro
Müller, Maurer, Reimers et al
Int. J. Oncol. (2015)
Müller, Maurer, Reimers et al
Int. J. Oncol. (2015)
Cited by 13
Showing 1-1 of 1 papers.
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complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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