Superoxide Dismutase 1 (SOD1) (NM_000454) Human Recombinant Protein

CAT#: TP300725

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Recombinant protein of human superoxide dismutase 1, soluble (SOD1)


 Product Datasheet for 'TP300725'

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USD 748.00


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Size
    • 20 ug


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Specifications

Product Data
Description Recombinant protein of human superoxide dismutase 1, soluble (SOD1)
Species Human
Expression Host HEK293T
Expression cDNA Clone or AA Sequence Recombinant protein was produced with TrueORF clone, RC200725. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag C-Myc/DDK
Predicted MW 15.8 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Reference Data
RefSeq NP_000445
Locus ID 6647
Refseq Size 981
Cytogenetics 21q22.11
Refseq ORF 462
Synonyms ALS; ALS1; HEL-S-44; homodimer; hSod1; IPOA; SOD
Summary The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome
Protein Pathways Amyotrophic lateral sclerosis (ALS), Huntington's disease, Prion diseases

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