p73 (TP73) (NM_005427) Human Mass Spec Standard

SKU
PH320864
TP73 MS Standard C13 and N15-labeled recombinant protein (NP_005418)
  $3,360.00
3 Weeks*
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Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC220864
Predicted MW 69.4 kDa
Protein Sequence
Protein Sequence
>RC220864 representing NM_005427
Red=Cloning site Green=Tags(s)

MAQSTATSPDGGTTFEHLWSSLEPDSTYFDLPQSSRGNNEVVGGTDSSMDVFHLEGMTTSVMAQFNLLSS
TMDQMSSRAASASPYTPEHAASVPTHSPYAQPSSTFDTMSPAPVIPSNTDYPGPHHFEVTFQQSSTAKSA
TWTYSPLLKKLYCQIAKTCPIQIKVSTPPPPGTAIRAMPVYKKAEHVTDVVKRCPNHELGRDFNEGQSAP
ASHLIRVEGNNLSQYVDDPVTGRQSVVVPYEPPQVGTEFTTILYNFMCNSSCVGGMNRRPILIIITLEMR
DGQVLGRRSFEGRICACPGRDRKADEDHYREQQALNESSAKNGAASKRAFKQSPPAVPALGAGVKKRRHG
DEDTYYLQVRGRENFEILMKLKESLELMELVPQPLVDSYRQQQQLLQRPSHLQPPSYGPVLSPMNKVHGG
MNKLPSVNQLVGQPPPHSSAATPNLGPVGPGMLNNHGHAVPANGEMSSSHSAQSMVSGSHCTPPPPYHAD
PSLVSFLTGLGCPNCIEYFTSQGLQSIYHLQNLTIEDLGALKIPEQYRMTIWRGLQDLKQGHDYSTAQQL
LRSSNAATISIGGSGELQRQRVMEAVHFRVRHTITIPNRGGPGGGPDEWADFGFDLPDCKARKQPIKEEF
TEAEIH

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_005418
RefSeq Size 2234
RefSeq ORF 1908
Synonyms P73
Locus ID 7161
UniProt ID O15350
Cytogenetics 1p36.32
Summary This gene encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors, and thought to contain multiple tumor suppressor genes. The demonstration that this gene is monoallelically expressed (likely from the maternal allele), supports the notion that it is a candidate gene for neuroblastoma. Many transcript variants resulting from alternative splicing and/or use of alternate promoters have been found for this gene, but the biological validity and the full-length nature of some variants have not been determined. provided by RefSeq, Feb 2011
Protein Families Druggable Genome, Transcription Factors
Protein Pathways Neurotrophin signaling pathway, p53 signaling pathway
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Documents
Resources
Other "p73" proteins (7)
SKU Description Size Price
PH325696 TP73 MS Standard C13 and N15-labeled recombinant protein (NP_001119714) 10 ug
$3,360.00
LC417321 Lyophilized TP73 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC426670 Lyophilized TP73 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY417321 Transient overexpression lysate of tumor protein p73 (TP73), transcript variant 1 (as WB positive control) 100 ug
$665.00
LY426670 Transient overexpression lysate of tumor protein p73 (TP73), transcript variant 4 (as WB positive control) 100 ug
$436.00
TP320864 Recombinant protein of human tumor protein p73 (TP73), transcript variant 1, 20 µg 20 ug
$867.00
TP325696 Purified recombinant protein of Homo sapiens tumor protein p73 (TP73), transcript variant 4, 20 µg 20 ug
$867.00

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